/Aateria^e.dica 




LIBRA! )NGRESS. 

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' Copyright No. 



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597 



UNITED STATES OF AMERICA. 



TEXT-BOOK 



OF 



MATERIA MEDICA 

FOR NURSES 



COMPILED BY 

LAVINIA L. DOCK 

GRADUATE OF BELLEVUE TRAINING SCHOOL FOR NURSES 



THIRD EDITION, REVISED AND ENLARGED 
ELEVENTH THOUSAND 



G. P. PUTNAM'S SONS 

NEW YORK LONDON 

27 WEST TWENTY-THIRD STREET 24 BEDFORD STREET, STRAND 

Vyt guxickerbockw IpHSS 
1897 

a:. 




TWO C9Hf:S RECEIVED 






Copyright 1890 

BY 

LAVINIA L. DOCK 



Copyright 1897 

BY 

G. P. PUTNAM'S SONS 



Ube Iknfcfcerbocfcetr press, mew lorfc 



CONTENTS 



PAGE 

Part I. — The Inorganic Materia Medica : 

The Alkalies and Alkaline Earths ..... I 

The Metals . . ' 18 

Non-Metallic Elements ,49 

Inorganic Acids ........ 63 

Organic Acids . . . . . . . .68 

The Carbon Compounds ....... 76 

Part II. — The Organic Materia Medica : 

The Vegetable Kingdom . . . . . . .113 

The Animal Kingdom . . . . . . 204 

New Drugs Arranged Alphabetically .... 211 

Appendix. 223 

Index 227 



PREFACE- 



The study of materia medica is made, to some ex- 
tent, a part of the course in all our training schools for 
nurses ; bat, so far, no text-book has been prepared 
along the special lines followed in class recitations. 

Those special lines are well defined, and are limited. 
They begin and end with medicines, and do not run 
into therapeutics. The application of medicine to dis- 
ease is no part of a nurse's study, and there are there- 
fore some inconveniences met with in using — as text- 
books — works on materia medica which are written 
solely for the use of the medical profession. 

Large works, containing all the points which a nurse 
needs to know, contain also an immense amount of mat- 
ter with which she has nothing to do, and are very ex- 
pensive ; while those which are more concise usually 
presuppose a large amount of information, and are, in- 
deed, not intended to be used at the beginning of a 
course of study, but rather at the end. 

It is in the hope of filling this middle place that this 
text-book has been compiled, and the attempt made to 
collect from all available sources the scattered points 
which concern a nurse, and to give them simply and 
directly. The outlines followed are those of the classes 
in materia medica as taught in most of our Training 
Schools for nurses, and include something of the source 
and composition of drugs ; their physiological actions ; 
signs indicating their favorable or unfavorable results ; 
the symptoms of poisons with their antidotes ; and prac- 
tical points on administration. 

For material I am indebted to the following works : 
" Materia Medica and Therapeutics," by Dr. H. C. Wood ; 



VI PREFACE. 

" Quiz Compend of Materia Medica," by Dr. S. 0. Potter ; 
" Materia Medica and Therapeutics," by Dr. R. Bartho- 
low ; " Lectures on Materia Medica and Therapeutics," 
by Dr. Thomson, edited by Dr. Le Fevre ; " Manual 
of Pharmacology, Therapeutics, and Materia Medica," 
by Dr. T. Lauder Brunton ; " Materia Medica and 
Therapeutics," by Dr. J. Mitchell Bruce ; and Dr. 
Farquharson's " Guide to Therapeutics and Materia 
Medica," edited by Dr. Woodbury. 

I gratefully acknowledge the kind permission accorded 
by the authors and publishers of the first five works to 
make extracts from them. For the use of the two lat- 
ter I am indebted to the courtesy of Messrs. Lea Brothers. 
Sincere thanks are due also to Dr. Charles Rice for 
much kindness in giving assistance and information, 
and in contributing a table of comparison between 
minims and drops ; and to Dr. George Dock for revi- 
sion and corrections and for many practical suggestions. 
The classification follows that used by Dr. Brunton 
and Dr. Bruce. The doses are taken from Dr. Wood's 
" Materia Medica and Therapeutics." 



PREFACE TO THE THIRD EDITION. 



In response to various suggestions I have added a 
number of drugs, both old'and new, and have given the 
metric system of dosage in addition to the old measure- 
ments. 

For all of the work on the preliminary chapter descrip- 
tive of the metric system, the classification of drugs ac- 
cording to their physiological effects, and the table of 
poisons and antidotes, I am indebted to Miss Mary 
Cloud Bean of the Johns Hopkins Training School for 
Nurses. 



INTRODUCTION. 

The broad meaning of medicine {Medicina) is " the 
science and art of healing and curing the sick " (Gould) ; 
but aside from this meaning the word is used in a re- 
stricted sense, to signify a drug used for the cure or re- 
lief of disease. The word drug means " a substance, 
simple or compound, natural or prepared, single or mixed 
with other substances, used as a medicine " (Gould); and 
" Materia Medica " covers the entire list of such sub- 
stances, with their whole history. 

On beginning the study of Materia Medica a general 
knowledge should be acquired of the classification of 
drugs considered from three standpoints : 
I. Their source or derivation. 
II. Their physiological actions. 

III. Their ultimate forms and appearance as prepared 
in the pharmacy by definite, standard formulae, for ad- 
ministration. 

I. Both the organic and inorganic worlds furnish ma- 
terial useful for medicine, and in the former both the 
animal and vegetable kingdoms are represented. The 
class of inorganic drugs is large, and comprises alkalies, 
alkaline earths, acids, metals and non-metals, and com- 
plex chemical compounds, as the carbon compounds. 
Among them all are many familiar elements, as lead, 
iron, etc. 

The animal kingdom furnishes but a small quota. The 
drugs of vegetable origin are by far the most numerous, 
and are obtained from green and flowering plants, both 
fresh and dry, fungi, and lichens. The whole plant may 
be represented or a part only, as the flowers, seeds, fruit, 



X INTRODUCTION. 

stems, or roots. The constituents of vegetable drugs are 
many and varied in character, some of them being of 
great potency. They are extracted from the plant and 
isolated in a pure form by elaborate chemical processes, 
and by means of especially constructed appliances. 

The principal ones are as follows : Aromatic, odorous, 
and bitter principles, albuminous bodies, starches and 
sugars, glucosides, oils, gums, resins and oleo-resins, and 
alkaloids. Gums are exudations from the stems of plants. 
Resins are solid, brittle, non-volatile substances, insoluble 
in water ; and oleo-resins may be broken up into resins 
and volatile oils. 

The alkaloids are the most important, forming as they 
do a class of poisons of marked characteristics and great 
intensity. They are nitrogenous compounds, many of 
them of deadly power, and are spoken of as the " active 
principles " of those drugs in which they are found, and 
to which they lend their own distinctive properties. The 
name alkaloid is given to them from their similarity in 
many ways to alkalies. 

The other constituents of vegetable drugs are relatively 
unimportant. 

II. In considering drugs in reference to the second 
division we find them grouped according to the effect 
they have on the human organism in disease. This mode 
of classification must be grasped broadly, not by rule. It 
is impossible to assign fixed and definite places to all 
medicines from this standpoint, or to draw sharp lines of 
division. Remembering the complex nature of plants, 
and that one drug may contain more than one active alka- 
loid, and a number of the less important substances just 
named, it is evident that one medicine may have several 
actions ; and practically it is found that their effects arc 
as scales of varying gradation, and run insensibly into 
one another. The same drug that in small doses acts as 
a beneficent agent, may in large ones be an overwhelming 
poison. One given to quiet the nervous system may also 
constipate ; another given for purgation may seriously 
reduce the strength of the heart ; another given to 
strengthen the heart may also increase the flow of urine, 



IN TROD UCTION. XI 

so that classification may well be sometimes a little 
puzzling. 

It will dispel bewilderment to remember that the most 
important and prominent characteristic of a drug is usu- 
ally taken -as its representative quality, the others being 
for the time ignored. 

Individual peculiarities have much to do in modifying 
the physiological actions of drugs. The more highly 
strung nervous organizations respond more quickly, as a 
rule, to the actions of drugs than do those of coarser fibre, 
and more quickly show evidence of over-dosing and mild 
poisoning. Among these temperaments are found many 
examples of what is called " idiosyncrasy " — that is, an 
increased susceptibility to the effects of a drug which en- 
tirely forbids its use, and for which no reason can be 
discovered. 

Custom makes a decided difference, and the action of 
a medicine is more energetic with one unused to it. With 
frequent repetition comes "toleration," when the, system 
accommodates itself to the drug, and larger doses can be 
taken with relatively less effect. Beyond this point comes 
"habit," when the system not only tolerates but craves 
the drug in ever increasing quantities, and with the result 
of a progressive degradation of the will power, as is most 
strikingly shown in the ascendency of alcohol and opium 
over the individual. 

" Accumulation " and " cumulative action " of drugs 
are expressions often met and are self-explanatory up to 
a certain point. While it might be difficult to explain the 
exact processes in the body tissues by which drugs are 
stored up or accumulate in them, it is, fortunately, sufficient 
for practical purposes to know that a number of drugs do 
become apparently fixed in the tissues, and that many 
others accumulate by being given more rapidly than they 
can be excreted. 

Age is an important factor to consider. Strong drugs, 
and especially those that act on the brain, are given with 
much care to children and to the aged. The condition of 
the stomach is another point to consider. Medicines act 
more rapidly on an empty stomach, and any irritating 



Xll INTRODUCTION. 

properties they may have are then more marked. Given 
with or soon after food the action is more gentle and slow. 
The kinds of food taken are to be thought of, and any 
which might neutralize the medicine should be put off for 
a safe interval. In giving medicines to produce sleep, all 
conditions favorable to sleep must first be secured. The 
good effect of many a hypnotic is lost through the failure 
to provide darkness, warmth, and quiet before giving it. 

In general the effects of medicines are classed as pri- 
mary and secondary, immediate or remote. By the primary 
or immediate action is meant the first definite result of 
the drug, and subsequent changes which are brought 
about by this first result are termed the secondary or re- 
mote effects, viz., if a diuretic is administered to a drop- 
sical patient a copious flow of urine soon occurs as the 
primary effect. As a result of increased urination fluid 
is largely abstracted from the body tissues, and the con- 
sequent diminution of the dropsy is the secondary effect. 
The classes of medicine according to their physiological 
actions are arranged alphabetically as follows : 

Antispasmodics. — Those which relieve convulsions 
and spasmodic pains (Gould): 

Anaesthetics. — Those which produce a state of in- 
sensibility to pain. They may be (a) general, as ether ; 
or {b) local, as cocaine. 

v Astringents. — Those which tend to contract the 
tissues, thus checking secretions. 

Alteratives. — A rather vague term, not universally 
approved, applied to certain drugs which have an unex- 
plainable power over the nutritive processes. 

Anodynes, Analgesics. — Those which give relief 
from pain. 

Antiperiodics. — Those which break up the rhythmical 
character of some manifestations of disease, as chills in 
ague. 

Antipyretics. — Those which reduce fever. 

Antacids. — Those which counteract acidity. 

Anthelmintics. — Those used to expel (vermifuge) or 
kill (vermicide) intestinal parasites. 

Absorbents. — Those which produce absorption and 
exudation of diseased tissue (Gould). 



INTRODUCTION. xill 

Analeptics. — Restorative medicines, or food. 

Antiarthritics. — Medicines which relieve gout. 

Antihydropics. — Those which relieve dropsical con- 
ditions. 

Antilithics. — Those which dissolve calculi. 

Antiseptics. — Medicines which prevent putrefaction. 

Antizymotics. — Those which have power to kill 
disease germs. 

Aromatics. — Medicines characterized by a spiciness 
of odor and taste, stimulant to the gastro-intestinal mu- 
cous membrane. 

Bitters— Simple. — Medicines which have a bitter 
taste and power of stimulating the gastro-intestinal tract 
without affecting the general system. 

Bitters — aromatic. — Those which unite the proper- 
ties of the aromatics and the bitters. 

Carminatives are slightly stimulant, and expel gas 
from the stomach and intestines. 

Cardiac Stimulants. — Those which strengthen the 
heart's action. 

Cardiac Depressants. — Those which weaken the 
heart's action. 

Cathartics, Purgatives.— Those which produce 
evacuation of the bowels. They are subdivided as fol- 
lows : laxatives, or aperients, those of gentle actiom 
among which are fruits and some vegetables ; drastic 
cathartics, those of severe action causing griping ; hydra- 
gogue cathartics, those which remove water freely from 
the intestines. Some of the drastics belong to this class, 
and all salines. Saline cathartics produce a copious flow 
of serum from the intestinal walls into the canal. The 
blood serum being of one degree of alkalinity and the 
salts a much stronger solution, an active exchange takes 
place until the two are equalized. It was formerly taught 
that salts should be given in a large quantity of water, but 
Dr. Hay teaches giving them in saturated solution, and 
states that it is not the amount of water in the canal, but 
in the tissues that is of importance, and that purgation 
may be prevented by withholding water from the diet for 
a day or two. 



XIV ' INTRODUCTION. 

Calefacients. — Those used to produce a sense of 
warmth. 

Caustics. — Drugs which have the power of destroy- 
ing living tissue. 

CholagOgues. — Those which cause a flow of bile. 

ConvulsantS — Those which cause convulsions. 

Correctives. — Medicines used to correct or render 
more pleasant the action of other remedies, especially 
purgatives. 

Diluents. — Those which dilute the secretions of or- 
gans. 

Diaphoretics. — Those which increase the action of 
the skin and produce perspiration. 

Diuretics. — Those which increase the flow of urine. 

Depresso-Motors. — Those which lessen the activity 
of the spinal cord and motor centres (Gould). 

Demulcents. — Mucilaginous principles which are 
used in solution to soothe and protect irritated mucous 
membranes or other tissues. 

Deodorants. — Substances which destroy or hide foul 
odors. 

Depilatories.— Those used to remove hair. 

Depurants. — Medicines which stimulate excretions 
and so purify the system. 

Detergents. — Those which cleanse wounds, ulcers, 
etc. 

Disinfectants. — Those which have the power of 
destroying disease germs or noxious properties of or- 
ganic matter. 

Excito-Motors. — Those which increase the activity 
of the spinal cord and motor centres (Gould). 

Emetics. — Those which produce emesis or vomiting : 
(a) local emetics, those that act directly on the nerves of 
the mucous membrane of the stomach, and (fi) systemic 
emetics, those that act on the vomiting centres in the 
medulla. 

Expectorants. — Those which increase bronchial 
secretions. 

Emmenagogues. — Those which stimulate the men- 
strual flow. 



IN TROD UCTION. XV 

Ecbolics. — Those which produce abortion. 

Emollients. — Substances used to soften and protect 
tissue. 

Errhines. — Medicines which increase the nasal se- 
cretion. 

Evacuants. — A term applied to purgatives. 

Epispastics, Escharotics. — Those which produce 
blisters and sloughing. 

Febrifuges. — Medicines which dissipate fever. 

GalactagOgues. — Those which increase the secretion 
of milk. 

v Hypnotics. — Those which produce sleep, but have 
no power over pain. All anodynes are also hypnotics, 
but all hypnotics are not anodynes. 

Haemostatics. — Such as arrest hemorrhage. 

Mydriatics. — Drugs which cause mydriasis or dilata- 
tion of the pupil. 

Myotics. — Those which cause myosis or contraction 
of the pupil. 

Narcotics. — Those which have intensified ano- 
dyne and hypnotic power, producing a condition of 
stupor. 

Neurotics. — Those which act on the nervous sys- 
tem. 

Nutriants. — Drugs which modify nutritive pro- 
cesses. 

Nutrients. — Substances which nourish. 

Oxytocics. — Medicines which stimulate uterine con- 
tractions. 

Prophylactics. — Medicines which prevent the taking 
or development of a disease. 

Refrigerants. — Those which lessen the body tem- 
perature. 

Revulsants. — Those which, by causing irritation, 
serve to draw the blood from a distant diseased part. 
Counter-irritants. 

Rubefacients. — Those which redden the skin by 
distending the capillaries. Rubefacients, epispastics, and 
escharotics must be classified loosely, as many drugs have 
all three actions, according to the length of time and 



xvi INTRODUCTION. 

seventy of application. Nitrate of silver is an eschar- 
otic which does not belong to the other two classes. 

Sedatives. — Those which have a soothing effect by 
lowering functional activity (Gould). 

Stomachics. — Stimulants exciting the functional 
activity of the stomach. 

Sialagogues. — Those which produce an increased 
flow of saliva. 

Sorbefacients. — Medicines which cause absorp- 
tion. 

Sudorifics. — Those which produce sweating. 

Somnifacients and Soporifics. — Those which cause 
sleep. 

Specifics. — Those which have direct curative influ- 
ence on certain individual diseases. 

Stimulants. — Those which increase functional ac- 
tivity. 

Styptics. — The same as haemostatics. 

Taeniacides. — Drugs which kill tape-worms. 

Tonics. — Those which promote nutrition and give 
tone to the system. 

Vesicatories. — Blisters. 

III. The preparation of medicines from the crude 
drug is carried on in drug mills and pharmacies by 
many processes of great nicety and by exact formulae 
which place them, when completed, in distinct classes, 
each class differing from all others in one -or more 
particulars. To standardize the preparation of drugs, 
each country has its Pharmacopeia, or authorized publi- 
cation containing the list of such drugs and their prep- 
arations as are declared official for that country. 
Abroad the national Pharmacopeias are established by 
law. In this country, representatives of the medical 
and pharmaceutical professions together formulate the 
U. S. P., and appoint a committee to revise it every ten 
years. 

Dispensatories are private unofficial publications — com- 
mentaries on the Pharmacopeia, treating with much detail 
not only those official drugs contained in it, but unofficial 
ones, and their preparations also. The Dispensatory gives 



INTRODUCTION. 



XV11 



doses, but the Pharmacopeia does not. The classes of 
preparations of the U. S. P. are as follows, a few being 
omitted as unimportant : 



LIQUID PREPARATIONS. 

Decoctions, Decocta. 
Infusions, Infusa. 
Solutions, Liquores. 
Waters, Aquce. 
Tinctures, Tincturce. 
Fluid extracts, Extracta Jluida. 
Spirits, Spiritus. 
Wines, Vina. 
Mixtures, Misturce. 
Vinegars, Aceta. 
Oleates, Oleata. 
Oleo-resins, Oleoresince. 
Glycerites, Glycerita. 
Syrups, Syrupi. 
Mucilages, Mucilagines. 
Liniments, Linimenta. 



SOLID PREPARATIONS. 

Extracts, Extracta. 
Resins, Eesina. 
Cerates, Cerata. 
Confections, Confectiones. 
Pills, Pilulce. 
Powders, Pulveres. 
Papers, Charta. 
Ointments, Unguenta. 
Plasters, Emplastra. 
Lozenges, Trochisci. 
Suppositories, Suppositoria. 



LIQUID PREPARATIONS. 

Decoctions.— Made by boiling the drug in water. A 
method used for hard fibrous or wood plants. There are 
but two official decoctions. They are made in a strength 
of 5 ^ unless otherwise directed. 

Infusions. — Made by treating a vegetable drug with 
either hot or cold water without boiling. Four official. 
The strength is the same as that of decoctions. 

Solutions. — Preparations of non-volatile drugs dis- 
solved in water. Twenty-four official. 

Waters. — Solutions of volatile principles dissolved 
in water. 

Tinctures. — Preparations of non-volatile substances 
(except one, iodine) dissolved in alcohol. In the revis- 
ion of the Phar ma copeia of 1890, the proportion of drug 
to the finished tincture has been made, wherever practi- 
cable, either 5, 10, 15, or 20 </ by volume. There are, 
however, exceptions to this general rule. There are 
seventy-one official tinctures. 

Fluid Extracts. — Concentrated tinctures or alco- 



XV 1 1 1 INTRODUC TION. 

holic extracts of definite strength. One c.c. of a fluid 
extract represents i gramme of the drug ; or, i minim 
represents i grain, approximately. Eighty-eight official. 

Spirits. — Solutions of volatile substances in alcohol. 
Twenty-five official. 

Wines. — Preparations made with a basis of wine. 
Ten official. 

Mixtures. — Watery preparations holding an insoluble 
substance, finely subdivided, in suspension. Emulsions 
belong to this class, an oil being suspended in the mix- 
ture. There are four official mixtures and four official 
emulsions. 

Vinegars. — Preparations made with dilute acetic 
acid. 

Oleates. — Preparations made with oleic acid. Three 
official. 

Oleo-resins. — Preparations containing a mixture of 
natural oils and resins extracted from vegetable sub- 
stances by the action of ether. They are the most con- 
centrated of liquid preparations. Six official. 

Glycerites. — Preparations made with a basis of glycer- 
ine. Six official. 

Syrups. — Preparations made with sugar and water, 
sometimes containing alcohol. Simple syrup is sugar 
and water. Thirty-two official. 

Mucilages. — Preparations of soluble gummy sub- 
stances dissolved in water. They spoil very quickly. 
Four official. 

Liniments. — Preparations for external application 
with friction. They have an oily or soapy character. 
Nine official. 

SOLID PREPARATIONS. 

Extracts. — Semi-solid or solid preparations, made by 
evaporation. Thirty-two official. 

Resins. — Peculiar substances soluble in alcohol and 
insoluble in water. Obtained from saturated tinctures 
bv precipitating with water. It is the resinous con- 
stituent which causes the thick precipitate seen when 



INTRODUCTION. XIX 

compound tinctures are diluted with water. Such prep- 
arations are better diluted with weak wine. Four 
official. 

Cerates. — Preparations made for inunction with 
white wax. Six official. 

Confections. — Medicinal substances prepared with a 
mass of sugar and honey. Two official. 

Pills. — Fifteen official. Need no general description. 

Powders. — Nine official. Need no general de- 
scription. 

Papers. — Papers impregnated with medicinal sub- 
stances. Two official, which are for vesication. The 
word " charta " also means the small papers in which 
powders are done up, or, by inference, the powder itself. 

Ointments. — Preparations with a basis of vaseline, 
fixed oils, or lard, to be used by inunction. Twenty- 
three official. 

Plasters. — Medicinal substances mixed with usually 
a lead preparation or Burgundy pitch spread upon coarse 
muslin, and adherent at the body temperature to the 
skin. Thirteen official. ^ 

Lozenges.— There are fifteen off ial. 

Suppositories. — Slender cone-shaped appliances for 
insertion into the rectum. The basis is usually cocoa 
butter. 

We find the metallic poisons, as prepared for medicinal 
use, usually in solution, after being changed in form by 
the action of various other chemical agents. Among 
tinctures, on the other hand, are found many of those 
vegetable drugs from which are obtained the powerful 
alkaloids. But if the pure alkaloids alone are desired, as 
they are insoluble in water and only partly so in alcohol, 
they must be treated as the metals are, and combined 
with an acid to make them ready for ingestion. In this 
combination both metals and alkaloids form what are 
called " salts" — being perfectly soluble in water yet re- 
taining all their medicinal qualities. Thus one reads of 
the " salts " of iron, the " salts " of strychnia, etc. Various 
acids are used, but the most common one is sulphuric 
acid, as it is cheap. These salts are then finally pre- 



XX INTR OD UC TION. 

pared for use in solution, and distinguished from each 
other by the name of the acid used — e.g., " the solution 
of the sulphate of morphia," the " hydrochlorate of co- 
caine," etc. 

As solutions are made in varying strengths the face of 
the bottle is always carefully marked either with the per- 
centage or with the amount to the drachm. 

A saturated solution is one that cannot be made any 
stronger The water holds in solution all that it can 
dissolve, and any additional solid material would be 
deposited as a sediment. All saturated solutions are 
not of the same strength, as water dissolves different sol- 
ids in different proportions. Solutions decompose very 
readily. The appearance of a fungus shows when decom- 
position has occurred. 

Almost all preparations of drugs are injured by age ex- 
cept whiskey, brandy, etc. Tinctures and fluid extracts 
become stronger by reason of evaporation of their alcohol. 
Infusions lose their strength Many preparations are in- 
jured by light and air, as the silver solutions, and others 
are unstable as to composition. 

Medicinal agents maybe applied: (i) to the skin in 
various ways, viz., by inunction, as oils, liniments, and 
ointments rubbed into the skin ; by simple contact with* 
out rubbing, as medicated baths, cooling or sedative mix* 
tures, blisters, plasters, powders, etc , and by painting, as 
iodine ; (2) to mucous membranes, as gargles, insuffla- 
tions, sprays, and douches ; (3) to wounds and diseaseo. 
tissue, as antiseptic powders, ointments, and solutions ; 
or they may be administered (4) by inhalation, as fumes 
or vapor ; (5) by hypodermic injection into the subcuta- 
neous tissues ; (6) by the mouth, or by the rectum, into 
the alimentary canal. 

By the first three ways, the effects produced are, gen- 
erally speaking, local (though in many instances the local 
impression may be deepened into a general one) and 
results are slow. 

Inhalation is a rapid mode of impressing the system, 
but only a few drugs are fitted for use in this way. 

Drugs given hypodermically act most promptly, because 



IN TR OD UC 1 ION. XXI 

they go directly into the blood current, and are diffused 
through the tissues in a short time. Only highly concen- 
trated or powerful agents which are active in small bulk 
can be given in this way ; and of these, many, otherwise 
available, are forbidden on account of their irritant 
properties. 

Medicines are most often given by way of the aliment- 
ary canal, and the rectum is used when for any reason it 
is not desirable to use the stomach. 

Having entered the circulation by whatever route, a 
drug is carried by the blood to the tissues, and is finally 
eliminated, or cast off as waste product, by the excretory 
organs. 

As the methods of administering medicines, giving hy- 
podermic injections, and otherwise applying drugs are 
fully discussed in nursing text-books, they will not be 
touched on here. The measurements commonly used in 
this country are the minim — TTI, the fluid drachm — 3, 
and the fluid ounce — J , or half ounce — ss. 

The minim is not by any means the exact equivalent of 
a drop, nor are all drops alike. A medicine ordered in 
minims must not be measured by drops, nor one ordered 
in drachms, by a teaspoon. 

It is hardly necessary to say that the nurse should 
always know what she is giving, and in what proportions. 
It is therefore essential that she should learn to read pre- 
scriptions, to recognize the most important ingredient or 
ingredients contained therein, and to find out by arith- 
metical process the exact amount of such ingredients con- 
tained in a given dose. 



A CLASSIFICATION OF DRUGS 

ACCORDING TO THEIR 
PROMINENT 'THERAPEUTICAL ACTIONS. 

This classification of the Materia Medica, being de- 
signed for the use of nurses, follows the order in which 
Anatomy is commonly taught in training schools for 
nurses ;. as it is thought that the study of those remedies 
most frequently employed in diseases of the various sys- 
tems of the body, taken in conjunction with the anatomy 
and physiology of each system, may induce a clearer com- 
prehension of both our Materia Medica and Anatomy, 
and at the same time serve to fix both in the mind. 
The page on which each drug is found is given in con- 
nection with its most prominent physiological action. 

THE CIRCULATORY SYSTEM. 

Drugs Acting on the Heart. 

Cardiac Stimulants, — increase both force and number of 
heart beats. 



Alcohol. 

Ether. 

Chloroform. 



Strychnine. 

Ammonia. 

Atropine. 



Normal salt solution, one of the most efficient cardiac 
stimulants, has only a mechanical action, supplying a 
fluid of the same specific gravity as the blood, which the 
heart pumps upon until the natural circulation is restored: 

Cardiac Tonics, — increase force of heart's contraction, 
lessening frequency. 

Strychnine. 
Convallaria. 196. 
Adonis Vernalis. 118. 



Digitalis. 178. 
Strophanthus. 170. 
Squill. 194. 
Caffeine. 



Sparteine. 139. 



A CLASSIFICATION OF DRUGS. XXlll 



Cardiac Sedatives , — lessen force and frequency of pulse. 



Aconite. 113. 
Veratrum Viride. 197. 
Antimony. 46. 



Pilocarpine. 

Ergot. 

Digitalis. 



Drugs Acting on the Vessels. 



Vascular Stimulants, — dilate the vessels through vaso- 
motor centres, equalizing blood-pressure. 

Liquor Ammoniae Acetatis. 

Alcohol. 

Ether. 



Nitro-glycerine. 95. 
Amyl Nitrite. 93. 
Lobelia. 



Vascular Sedatives. 
See Haematinics and Antiphlogistics. 

THE RESPIRATORY SYSTEM. 

Drugs Acting on Respiration. 

Respiratory Stimulants, — stimulate respiration by action 
on brain centres. 



Strychnine. 
Ammonia. 12. 
Aconite. 



Belladonna. 171. 
Hyoscyamus. 176. 
Stramonium. 175. 



Respiratory Depressants, — lower action of respiratory 
centre. 
Opium. Chloroform. 

Chloral. | Ether. 

Drugs Acting on the Bronchial Tubes. 

Pulmonary Sedatives, — relieve cough and dyspnoea. 

Opium. Belladonna. 

Hydrocyanic Acid. 72. Wild Cherry. 

Expectorants, — modify bronchial secretion and aid its 
expulsion. 

(1) Depressant Expectorants. 

Antimony. Alkalies. 

Ipecac. 



XXIV 



A CLASSIFICATION OF DRUGS. 



(2) Stimulant Expectorants. 

Ammonium Carbonate. 14. 

Ammonium Chloride. 13. 

Squill. 

Balsam of Peru. 141. 

Balsam of Tolu. 141. 

Inhalations, — used to stimulate 
secretions, or relieve spasm. 

Benzoin. 

Creasote. 

Turpentine. 

Oil of Eucalyptus. 



Terebene. 220. 
Senega. 130. 
Benzosol. 213. 
Creasote. 99. 
Acids. Syrups. 

the bronchi, disinfect 



Amyl Nitrite. 
Stramonium. 
Conium. 
Steam. 



THE DIGESTIVE SYSTEM. 
Drugs Acting on the Salivary Glands. 

Sialagogues, — increase flow of saliva. 



Pilocarpus. 
Mercurials. 




Pungents. 

Acids. 

Ether. 


Anti- Sialagogues, — decrease flo 


w of saliva. 


Atropine. 
Opium. 


Alkalies. 


Refrigerants, — allay thirst. 




Cold drinks. 
Dilute acids. 




Fruit juices. 
Many diaphoretics 



Drugs Acting on the Stomach. 



Emetics, — cause vomitinj 
Tartar Emetic. 46. 
Apomorphine. 129. 
Ipecac. 155. 
Sulphate of Zinc. 26. 



Mustard. 

Alum. 

Salt. 

Warm Water. 



Anti- Emetics, — relieve nausea and vomiting. 



Bromides. 

Chloral. 

Morphine. 

Cocaine. 

Creosote. 



Carbolic Acid. 

Iodine. 

Cerium Oxalate. 

Lime Water. 

Chloroform. 



18, 



A CLASSIFICATION OF DRUGS. 



XXV 



Carminatives. — aid in expulsion of gas from stomach and 

intestines. 



Asafoetida. 




Ginger. 189. 


Capsicum. 


177. 


Peppermint. 181. 


Cardamom. 


189. 


Cinnamon. 184. 


Camphor. 




Musk. 



Gastric Tonics or Stomachics, — excite the functional ac- 
tivity of the stomach, and thus increase appetite and 
aid digestion. 



Dilute Acids — 

Hydrochloric, etc. 
Vegetable Bitters — 

Gentian. 169. 

Quinine. 

Quassia. 137. 

Calumba. 119. 

Hydrastis. 118. 

Eucalyptus. 144. 

Wild Cherry. 144. 

Eupatorium. 

Chamomile. 

Taraxacum. 160. 

Cascarilla. 185. 

Aloes. 

Rhubarb. 

Pulsatilla. 

Nux Vomica. 



Antacids — 
All Alkalies- 
Potassium Bicarbonate. 
Sodium Bicarbonate. 
Aromatic Ammonia. 
Lime Water. 
Magnesia. 
Liquor Potassae. 
Liquor Sodae. 

Pepsin. 205. 

Pancreatin. 205. 
Alcohol. 



Drugs Acting on the Intestines. 

Cathartics, or Purgatives, — hasten intestinal evacuation. 



(1) Laxatives, — of moderate action. 

Sulphur. 60. 

Tamarinds. 

Prunes. 



Castor Oil. 186. 
Olive Oil. 164. 
Glycerine, in. 
Magnesia. 17. 

(2) Simple Purgatives - 
griping pari. 

Aloes. 195. 

Castor Oil. 

Cascara Sagrada. 138. 

Eupatorium. 



142. 



Figs. 



-produce active peristalsis and 



Senna. 142. 
Rhubarb. 182. 
Glycyrrhiza. 140. 
Licorice powder. 



XXVI 



A CLASSIFICATION- OF DRUGS. 



(3) Drastic Purgatives, — intense action, watery stools ; 
much pain. 



Scammony. 170. 

Jalap. 170. 

Aloes. 

Compound Cathartic Pills. 



Croton Oil. 185. 
Colocynth. 146. 
Elaterium. 147. 
Podophyllum. 116. 
Gamboge. 

(4) Saline Purgatives, — slight pain ; very watery evacu- 
ations. 
Salts of— 



Magnesium. 17. 
Sodium. 9. 
Potassium. 2. 



Saline Waters. 



(5) Cholagogue Purgatives, — remove bile from the in- 
testines. 
Mercurials — Podophyllum. 

Calomel. 40. Iris. 

Blue Mass. 41. 



Gray Powder. 41. 

Intestinal Antiseptics, — destroy low organisms ; 
fermentation (antizymotics). 

Salol. 102. Naphthalin. 104. 

Beta Naphtol. Silver Nitrate. 

Benzosol. Oil of Turpentine. 

Intestinal Astringents, — check secretion. 



check 



Bismuth Subnitrate. 

Alum. 

Lead Acetate. 

Silver Nitrate. 

Zinc Oxide. 

Iron. 



Tannic Acid. 
Gallic Acid. 
Sulphuric Acid. 64. 



Opium. 
Blackberry. 



143. 



Drugs Acting on the Liver. 



Hepatic Stimulants, or Cholagogues, — increase secretion 
of bile. 
Calomel. Colchicum. 



Podophyllin. 
Aloes. 
Colocynth. 
Rhubarb. 



Scammony. 

Jalap. 

Potassium Sulphate. 

Sodium Phosphate. 



A CLASSIFICATION OF DRUGS. 



XXVll 



Anthelmintics, — destroy (vermicides) or expel {vermifuges) 
intestinal worms of three kinds. 
(i) Tape worm, — 



Filix Mas. 204. 
Turpentine. 



Pelletierine. 145. 
Pepo. 148. 

( 2 ) Round worm, — 

Santonin. 159. I Spigelia. 164. 

Senna. | 

(3) Thread wor?n, — 

Sodium Chloride. Quassia. 157. 

Alum. Tannin. 

By enema. 

THE NERVOUS SYSTEM. 

Drugs Acting on the Spinal Cord and Nerves. 

Spinal Stimulants and Motor- Excitants, — stimulate cells 
of spinal cord ; act on motor nerves ; increase reflex 
excitability. 
Nux Vomica. 166. | Picrotoxin. 120. 

Spinal and Motor-Depressants, — lower the activity of 
spinal cord and motor apparatus. 



Bromides. 
Chloral. 
Belladonna. 
Nitrite of Amyl. 
Physostigmine. 141. 
Gelsemium. 164. 



Lobelia. 162. 
Tobacco. 177. 
Alcohol. 
Ether. 
Chloroform. 



Drugs Acting on the Brain and Nerves. 

Cerebral Stimulants, — increase the activity of the brain, 
most of them producing delirium if taken in large 
doses. Some (as alcohol) are narcotics at last. 



Cannabis Indica. 
Coca. 131. 
Coffee. 157. 
Tea. 158. 
Guarana. 131. 
Opium. 
Belladonna. 
Stramonium. 



Hyoscyamus. 
Chloral. 
Camphor. 
Alcohol — 76. 

Brandy. 81. 

Whiskey. 81. 

Wines. 82. 



XXV111 



A CLASSIFICATION OF DRUGS. 



lower or suspend the activity of 

— produce sleep. 
Hyoscine. 177. 
Cocaine. 128. 
Exalgine. 109. 
Trional. 221. 
Methylal. 217. 
Hypnal. 216. 
Somnal. 219. 



93- 



Cerebral Depressants, 
the brain. 

(1) Hypnotics, or Soporifics 

Bromides — 

Sodium. 55. 

Potassium. 54. 

Ammonium. 54. 

Lithium. 55. 
Chloral. 88. 
Amylene Hydrate. 
Paraldehyde. 91. 

(2) Narcotics, intensified hypnotic power. 
Opium. 120. J Bromal Hydrate 
Cannabis Indica. And others. 

Anesthetics, — produce insensibility to pain. 

( 1 ) General Ancesthetics. 
Ether. 86. 
Alcohol. 
Chloroform. 83. 

(2) Local Anesthetics. 
Cocaine. 131. 
Eucaine. 215. 
Ethyl Hydrate. 



213. 



Nitrous Oxide Gas. 
Many derivatives of 
Alcohols and Ethers. 



Carbolic Acid. 
Cold. 

Sterile water hypoder- 
mically. 



Anodynes, or Analgesics, — terms applied to relief of mild 
pain. 



( t ) General Anodynes. 
Belladonna. 
Stramonium. 

(2) Local Anodynes. 
Aconite. 
Carbolic Acid. 
Cocaine. 
Menthol. 181. 



All narcotics. 
Many hypnotics. 



Opium. 

Chloroform and other 

Liniments. 



Antispasmodics, — prevent or relieve spasm of muscle by 
action on nerve centres. 



Aromatic Oils. 
Asafoetida. 150. 
Valerian. 159. 
Amyl Nitrite. 
Bromides. 
Chloroform. 



Ether- 
Hoffman's Anodyne,etc, 
87. 
Alcohol. 
Camphor. 182. 
Musk. 



A CLASSIFICATION OF DRUGS. 



XXIX 



THE URINARY ORGANS. 

Drugs Acting on the Kidneys. 

Diuretics, — increase the quantity of urine. 

(i) Refrigerant, — modify character ; act on secret- 
ing cells ; increase quantity of both solids and 
fluids. 
Liquor Potassae. 4. Sodium. 

Potassium — Water — 

Acetate. 5. Pure. 

Citrate. 5. Carbonated. 

Nitrate. 8. Saline. 

Bitartrate. 7. 

(2) Hydragogue, — increase water in urine by local 

and general rise of arterial pressure. 

Digitalis. Scoparius. 139. 

Diuretin. 103. Convallaria. 

Spirits of Nitre. 87. Squill. 

Strophanthus. 

(3) Stimulant, — act locally, causing irritation of 
mucous membrane of entire genito-urinary tract. 



Copaiba. 140. 
Capsicum. 
Cubeb. 
Juniper. 193. 
Turpentine. 

Urinary Alkalinizers, 

Salts of— 
Potassium. 2. 



Buchu. 136. 
Cantharides. 
Taraxacum. 
Zea Mays. 
Alcohol. 



-render the urine alkaline. 



Lithium. 12. 
Sodium. 9. 



Urinary Acidifiers, — render the urine acid. 

Benzoic Acid. 163. | Salicylic Acid. 100. 

Lithontriptics, or Antilithics, — prevent deposition of the 
solids of the urine or assist in their resolution. 



Salts of— 
Potassium. 
Lithium. 
Sodium. 

Benzoic Acid. 



Ammonium Benzoate. 
Salicylic Acid. 
Piperazine. 219. 
Uricedin. 221. 
Lycetol. 217. 



XXX 



A CLASSIFICATION OF DRUGS. 



Drugs Acting on the Bladder. 

Vesical Sedatives, or Tonics, — improve the condition of 
muscle and mucous membrane of bladder and urethra, 
reducing inflammation. 



Zea Mays. 

Buchu. 

Copaiba. 

Cubeb. 

Eucalyptus. 

Belladonna. 

Opium. 



Strychnine. 

Salts of— 
Potassium. 
Lithium. 

Local antiseptic and as- 
tringent applications. 



THE GENERATIVE ORGANS. 

Emmenagogues, — restore or regulate the menstrual flow. 
Most of them are tonic and sedative to the uterus and 



ovaries. 

Hydrastis. 

Pulsatilla. 

Viburnum Prunifolium. 

Ergot. 

Myrrh. 

Oil of Rue. 136. 

Savine. 193. 

Tansy. 160. 



5i 



Indirect Tonics — 
Iron. 

Strychnine. 
Manganese. 
Cod-liver Oil. 
Aloetic Purgatives. 
Hot hip bath. 
Foot bath. 



Ecbolics, or Oxytocics, — cause contraction of the gravid 
uterus or of the uterus following childbirth. 



Ergot. 202. 

Quinine. 

Savine. 



Rue. 

Hydrastis. 
Cotton-root Bark. 



Uterine Depressants, — restrain contraction of the uterus. 

Opium. Chloroform. 

Chloral. Viburnum Prunifolium. 

Bromides. Cannabis Indica. 

Galactogogues, — increase the secretion of milk. 

Pilocarpus. I Milk. 

Leaves of Castor Oil plant. Fluids. 



A ntigalactogogues,- 
Belladonna. 



-decrease the secretion of miik. 
I Camphor. 



A CLASSIFICATION OF DRUGS. 



XXXI 



THE SKIN. 

Diaphoretics, — increase the secretion of sweat. Indirectly 
they aid the kidneys and reduce temperature. 

136. 



Pilocarpine. 
Salicylates. 
Dover's Powder. 
Nitrous Ether. 
Antimony. 
Eupatorium. 160. 
Potassium. 



127. 



Ammonium. 

Camphor. 

Alcohol. 

Heat. 

Acetanilid. 

Antipyrine. 

Asaprol. 212. 

And other synthetics. 



Anhidrotics, — diminish secretion of sweat. 
Atropine. Picrotoxin. 

Hyoscyamus. | Cold. 

Irritants. — Many drugs when applied to the skin pro- 
duce vascular excitement or irritation ; called counter- 
irritants if applied to excite reflex influence at a re- 
mote point. 

(1) Rubefacients, — cause redness of the skin. 



Mustard. 

Ammonia. 

Capsicum. 

Camphor. 

Veratrine. 



29. 



199. 



Iodine. 

Turpentine. 191. 
Arnica. 161. 
Heat. 
Friction. 



(2) Vesicants, or Epispastics, — produce blisters, or 
collection of serum beneath the epidermis. 

Cantharides. 207. | Mustard. 

(3) Pustulants, — produce pustules, or small collec- 

tions of white-blood corpuscles. 
Croton Oil. 185. | Tartar Emetic. 

Caustics, or Escharotics, — destroy the vitality of the 
tissues, producing a slough. 



Zinc Chloride. 
Nitrate of Silver. 

Mercury. 

Copper. 
Chloride of Antimony. 
Bromine. 



Lime. 

Caustic Soda. 

Potash. 

Acids- 
Carbolic. 
Sulphuric. 
Nitric. 64. 
Acetic (glacial). 



68. 



XXX11 



A CLASSIFICATION OF DRUGS. 



Astringents, — produce contraction of vessels and tissue 
and lessen secretion from mucous membrane. Known 
as remote or local astringents according as they act on 
internal organs or affect the part to which they are 
applied. 

As they chiefly affect the vessels they may also be 
considered in relation to the circulation. 



Gallic Acid. 72. 
Tannic Acid (71) and all 
substances containing 
it ; as — 
Galls. 

Hamamelis. 
Catechu, etc. 
Alum. 29. 



Acetic Acid. 
Salts of— 

Iron. 

Lead. 18. 

Silver. 23. 

Zinc. 25. 

Copper. 27. 

Bismuth. 



Antiphlogistics, — agents reducing or subduing inflam- 
mation or fever (Gould). They include all medicines 
and means to this end. 

Styptics, or H&iiiostatics, — arrest hemorrhage. 

All Astringents. 
Actual Cautery. 
Heat. Cold. 

■soften and protect skin or 



Ergot. 

Strychnine. 

Digitalis. 

Emollients and Demulcents, 
mucous membranes. 

Olive Oil. 
Vaseline, no. 
Lanolin. 204. 
Lard. 206. 
Cacao butter. 135. 
Glycerine. 
Starch. 

Lycopodium. 204. 
Borax. 12. 



Licorice. 140. 
White of egg. 
Barley water. 
Rice water. 
Flax Seed. 133. 
Tragacanth. 139. 
Acacia and other muci- 
laginous substances. 



Protectives, — used to cover a part. 

Collodion. 135. | Guttapercha, etc. 

THE EYE. 

Mydriatics, — cause dilatation of the pupil of the eye. 

Atropine. Cocaine. 

Duboisine. 



A CLASSIFICATION OF DRUGS. 



XXXlll 



Myotics, — contract the pupil. 
Physostigmine (Eserine). | 



Opium, etc. 



SUBSTANCES HA VING GENERAL SYSTEMIC 
EFFECT ON BLOOD AND TISSUE. 



Restoratives, — promote constructional tissue change. 

(i) Foods, — supply new material for repair and oxi- 
dation. 



Albumins. 

Starches. 

Sugars. 

Sodium Chloride. 9. 

Calcium Phosphate. 

Water. 



Fats. 

Oils- 
Olive. 164. 
Cod-liver. 206. 

Alcohol and other sub- 
stances. 



(2) Hcematinics, — increase the haemoglobin (red 
coloring matter) in the blood. 

Iron. 30. I Manganese. 35. 

(3) Tonics, — promote nutrition and give tone to the 
system. 



Strychnine. 
Quinine. 
Iron. 

Arsenic. 42. 
Vegetable Bitters. 
Phosphates. 49. 
Hypophosphites. 52. 
Cod-liver Oil. 



Acids- 
Hydrochloric. 65. 
Nitro-Hydrochloric, 
Phosphoric. 66. 
Lactic. 72. 
Citric. 69. 

Salicin 188. 

And other drugs. 



66. 



morbid 



Alteratives, — by some unknown process alter 
conditions and improve the nutrition of the body. 

Gold and Sodium Chloride. 



Sarsaparilla. 195. 
Colchicum. 200. 
Cod-liver Oil. 



[24. 



Mercury. 
Iodine. 56. 
Arsenic. 
Antimony. 

Antipyretics, — reduce fever (1) by promoting loss of heat 
and (2) by lessening its production. 



Cold. 

Antipyrine. 105. 
Acetanilid. 106. 
Salicylic Acid. 
Guaiacol. 100. 
Resorcin. 107. 



Phenacetine. 
Aconite. 
Quinine. 
Chinolin. 104. 
Asaprol 212. 
And others. 



108, 



XXXIV 



A CLASSIFICATION OF DRUGS. 



Antiperiodics, — lessen the severity or prevent the return 
of certain periodically recurring diseases. 

Quinine. 153. [ Eucalyptus. 

Hydrastis. 



ANTISEPTICS AND DISINFECTANTS. 



Antiseptics, — arrest the growth of or destroy micro- 
organisms. 

Disinfection relates to the complete destruction of the 
organism. 



Bichloride of Mercury. 37. 

Carbolic Acid. 96. 

Boric Acid and 67. 

Borax. 

Chloride of Zinc. 26. 

Oxalic Acid. 75. [36. 

Permanganate of Potassium. 

Salicylic Acid. 

Peroxide of Hydrogen. 63. 

Oil of Eucalyptus. 144. 

Thymol. 182. 

Quinine. 

Bismuth. 



Sulphurous Acid. 67. 
Iodoform. 59. 
Europhen. 215. 
Benzoin. 163. 
Lysol. 217. 
Aristol. 212. 
Dermatol. 214. 
Pyrogallol. 
Chlorine. 52. 
Naphthalin. 
Lime. 15. 
Creolin 214. 
And others. 



Deodorants, — remove disagreeable odors. 

Potassium Permanganate. Charcoal and 

Chloride of Lime. 53. 
Chlorinated Soda. 53. 



.Pa?-asiticides, 



Many others, 
destroy parasites on the skin. 



Staphisagria. 
Picrotoxin. 
Ichthyol. 62. 
Mercurials. 



116. 



Sulphur. 
Ether. 
Alcohol. 
Carbolic Acid. 



A TABLE OF POISONS: 
THEIR ANTIDOTES AND ANTAGONISTS. 

Antidotes act upon the poisons in the alimentary canal, 
and by combination or removal prevent their toxic 
action. 

Antagonists counteract the effect of the poison upon 
the system, and may be used after its absorption, when 
antidotes are too late. 



Acids — 

Hydrochloric. 
Phosphoric. 
Nitric. 
Sulphuric. 



Carbolic. 



Oxalic. 
Tartaric. 

Acetic. 



Hydrocyanic. 



Aconite. 



Alcohol. 



Alkalies — as Soda. 
Magnesia, Chalk, 
Lime-water, 
White-wash, Soap. 
Oil ; Albumen ; Milk. 
Demulcent Drinks. 

Sulphate of Magnesia. 
Sulphate of Soda. 
Lime-water ; Syrup of 

Lime. 
Milk. 
Vegetable demulcent 

drinks. No oil. 

Syrup of Lime; Chalk; 
Lime with water or 

milk. Emetics. 
Bland drinks. 

Emetics ; Stomach 

pump. 
Acts too quickly for 
any antidote to be of 

use. 



Empty and wash out 
stomach. 



Stomach tube or 
emetics. 



Stimulants. 
Opium. 



Atropine. 
Chloral. 
Stimulants. 
External heat. 



Stimulants. 
External heat. 



Artificial respiration. 

Cold water to head and 
spine. 

Stimulants by inhal- 
ation and hypoder- 
mically. 

Recumbent position. 
Artificial respiration. 
Heat. Atropine ; 
Ammonia ; Alcohol. 

Cold to head ; heat to 
extremities. Inhal- 
ation of Ammonia. 

Electricity. Coffee. 



XXXVI 



A TABLE OF POISON'S. 



POISON. 


ANTIDOTAL 
TREATMENT. 


ANTAGONISTIC 
TREATMENT. 


Alkalies- 
Ammonia. 
Caustic Potash. 
Caustic Soda. 
Lime. 


Dilute Acids. 
Vinegar. 
Lemon juice. 
Milk. 
Oil. 


For Ammonia — 
Aconite. 
Digitalis. 
Cold air. 


Anaesthetics — 

Chloroform. 
Ether, etc. 




Artificial respiration. 
Inversion of patient. 
Atropine ; Strychnine. 
Stimulants. Heat. 


Antimony — 

Tartar Emetic. 
Wine of Antimony. 
Syrup of Squills. 


Wash out stomach if 

necessary. 
Tannic Acid — as tea, 

etc. 
Demulcent drinks. 


Opium. 
Alcohol. 


Arsenic — 

Fowler's solution. 
Paris Green. 
Rough on Rats. 
Arsenous Acid. 


Emetics. Hydrated 
Oxide of Iron with 
Magnesia ; or the 
Hydrated Sesquiox- 
ide of Iron ; Dia- 
lyzed Iron. 

Demulcent drinks. 


Stimulants. 


Belladonna — 

Atropine. 


Evacuate stomach. 
Tannic Acid. 


Opium. 

Artificial respiration. 

External stimulants. 


Chloral. 


Wash out stomach with 
tea or coffee and give 
these per rectum. 


Heat. Mustard ap- 
plications. 
Artificial respiration. 
Alcoholic stimulants. 
Atropine (carefully). 


Copper. 


Albumens — as white 
of egg, milk, etc. 

Wash out stomach im- 
mediately after. 

Demulcents. 




Digitalis. 


Tannic Acid. 
Emetics, — as Sulphate 

of Zinc or of Copper, 

mustard, etc. 
Stomach tube. 


Recumbent position. 

Aconite. 
Stimulants. 



A TABLE OF POISONS. 



XXXV11 



POISON 


ANTIDOTAL 


ANTAGONISTIC 




TREATMENT. 


TREATMENT. 


Gases — 




Fresh air. 


Illuminating. 




Artificial respiration. 


Carbon dioxide. 




Stimulants. 


Chlorine. 






Gelsemium. 


Emetics. 


Opium. Stimulants. 
Artificial respiration. 
Heat. Electricity. 


Hyoscyamus. 


Same as Belladonna. 


Same as Belladonna. 


Iodine. 


Starch or flour with 

water. 
Emetics. 




Lead. 


Sulphate of Soda. 
Magnesia. Albumens. 
Emetics. 


Opium. 


Lobelia. 


Tannic Acid to wash 


Stimulants. 




out stomach. 


Strychnine. 


Mercury. 


White of an egg to 4 
gr. of the poison , 
milk ; flour. 

Wash out stomach. 




Mushrooms 


Wash out stomach. 


Atropine. 


(non-edible). 


Cathartic. 


Stimulants. 


Nitrate of Silver. 


Common salt. 




Strychnine. 


Tannic Acid. 


Quiet. Chloroform for 




Emetic quickly. 


convulsions. 
Chloral. Opium. 


Opium — 


Emetics. 


Keep patient awake. 


Laudanum. 


Stomach pump. 


Artificial respiration. 


Paregoric. 


Permanganate of 


Electricity. 


Morphine, etc. 


Potassium. 


External heat (care- 
fully). 

Coffee by mouth and 
rectum. 


Phosphorus. 


Emetics. 

No fats or oils. 


Atropine (with care). 




Old Oil of Turpentine. 


» 


Stramonium. 


Same as Belladonna. 


Same as Belladonna. 



THE METRIC SYSTEM. 

This system of weights and measures, first instituted 
by the French, is now in general use on the Continent of 
Europe, and is legalized in the United States, where it 
is employed in certain departments of the government 
and by scientific people at large. Many physicians and 
surgeons make use of the system, particularly in the 
prescription of medicines and in operating-room work. 
It therefore has become necessary that a nurse should 
understand it, while its simplicity, convenience, and 
accuracy commend the system to everyone. 

The metric tables which most concern a nurse's work 
are as follows : 

Weights. 



i milligramme = 
i centigramme = 
i decigramme = 
i gramme (gin.) = 
i decagramme = 
i hectogramme = 
i kilogramme = 



o.ooi 

O.OI 
O.I 
I.O 

IO.O 
IOO.O 

IOOO.O 



gramme. 



;rammes. 



metre. 



Length. 

i millimetre o.ooi 

i centimetre (cm.) o.oi 
i decimetre o.i 

i metre (m.) i.o 

Volume. 

It is unnecessary here to consider any other measure 
than the cubic centimetre, (cc), which is equal in 
volume to one millimetre. One cubic centimetre of 
water at a temperature of 4 Centigrade weighs one 
gramme, the unit of weight. 



THE METRIC SYSTEM. XXxix 

Capacity. 



i millilitre = 






o.ooi litre. 


i centilitre = 






O.OI " 


i decilitre = 






O.I 


i litre (1.) 


OR 




l.O 


I cc. = 


I 


erm. of water. 


IO " = 


IO 


a 


a a 


IOO " = 


IOO 


it 


a << 


IOOO " = 


IOOO 


u 


a <( _ 



= i kilo. 

The primary unit of the metric system is the metre 
(39.37 inches), which is approximately one ten-mil- 
lionth part of the distance from the equator to the 
north pole ; and from this as a basis the units of weight 
and capacity are readily derived, the remaining measure- 
ments in each table being obtained from their units by 
decimal subdivision and multiplication. It will be ob- 
served that any term less than the unit is expressed by 
the aid of a Latin prefix (deci, centi, milli), while Greek 
prefixes (deka, hecto, kilo) express multiplication, or 
terms greater. 

To mention the correspondence between the metric 
denominations and those of the United States currency, 
which is a metric currency, may serve to make under- 
standing more clear. It will be noticed that metres — 
for instance — correspond to dollars, decimetres to dimes, 
centimetres to cents, and millimetres to mills. Somewhat 
analogous to our method of reading currency is that of 
reading the metric system generally. 

For instance in the figures $5.25 we have represented 
dollars and cents, the latter being equal to t 2 q 5 o of a 
dollar. Similarly in the metric system these figures 
would stand for 5 and -f^Q of whatever the measure 
might be — whether of length or of capacity. 

Practically, of the table of capacities the litre and its 
multiplications only are used, as the cc. is more con- 
venient for small quantities. Frequently, instead of the 
litre, the term 1000 cc. is employed. The cubic centi- 
metre (cc), centimetre (cm.), and gramme (gm.) are the 



xl THE METRIC SYSTEM. 

terms the nurse most often meets with. The method of 
obtaining the gramme, the unit of the standard for 
weighing both solids and liquids, has been explained. 
In writing prescriptions this word is not expressed. 
Thus — 

Quininae sulphas 10.0. 

Common Measure and Metric Equivalents. 



i grain = 

i ounce Troy = 

i pound avoirdupois = 


0.065 gm, 

3 I - 10 3 " 
453-6 " 


i fluid drachm = 


3.70 cc. 


i fluid ounce = 


29 .57 ;; 


i pint = 


473.11 " 


i inch 


2.539 cm - 


i gramme = 
i kilo = 


I5-43 2 grains. 
2.204 1DS - av< 


i cubic centimetre = 


16.23 minims. 



1 litre (1000 cc.) = 33.81 fluid ounces. 

1 centimetre = °-393 inch. 

1 metre = 39-37 inches. 

Approximate Equivalents. 



I cc. = 
4*cc. = 


15 minims. 
1 fluid drachm. 


30 cc. = 


1 " ounce. 


1 gramme = 
1 decigramme = 


15! grams. 
t|- grains. 


1 centigramme 
1 milligramme 
1 litre = 
1 kilo = 


■£■ grain. 
eV grain. 

1 quart. 
2 -J- lbs. avoirdupois. 


1 cm. = 


f inch. 



To obtain the number of grammes, approximately, re- 
duce the quantity to grains and divide by 15. Or 

Reduce the quantity to drachms and multiply by 4 ; 
and proceed on like principles with other denominations. 



Table showing quantities from five grains down, ac- 
cording to the old tables, with their equivalents under 
the metric system : 





Grains 


Grammes. 








in decimal fractions. 


in common fractions 
(approximate). 


O.324 


5 


5 


O.29I 


4-5 


4* 


O.259 


4 


4 


O.226 


3-5 


3i 


O.I94 


3 


3 


O.162 


2.5 


H 


O.I3O 


2 


2 


O.O97 


1-5 


1* 


O.065 


1 


1 


O.061 


0.94 


1 5 


O.060 


0.93 


♦ 


O.057 


0.88 


7/8 


0.053 


0.82 


tf 


O.050 


0.77 


l 


O.049 


0.76 


O.045 


0.69 


u 


O.040 


0.62 


12 


O.036 


0.56 


♦ 


O.032 


0-5 


x /a 


O.028 


0.43 


A 


O.025 


o.39 


2 
5 


O.024 


o.37 


3 


0.020 


0.31 


* 


O.OI6 


0.24 


s /4 


O.OI2 


0.18 


A 


O.O08 


0.12 


Vs 


O.OC4 


0.06 


rV 


O.OO32 


0.05 


A 


O.OO27 


0.04 


A 


0.0022 


0.033 


A 


O.OOI8 


0.028 


A 


O.OOI6 


0.025 


A 


O.OOI3 


0.02 


A. 


O.OOII 


0.017 


A 


O.OOI 


0.015 


A 


0.0006 


O.OI 


xro' 


0.0005 


0.008 


T2¥ 


0.0004 


0.0065 


TO 


0.0003 


0.005 


¥inr 


0.0002 


0.003 


TSTT 


0.000 1 


0.0015 


•g-TTT 



2 MATERIA MEDICA FOR NURSES. 

the same physiological and therapeutic actions as the 
alkaloid. 

Potassa (Potassa). 

There are three great natural sources from which 
potassa arid its salts are derived, viz. : i. Wood ashes. 
2. Argol, the deposit left in wine-casks during the fer- 
mentation of grape-juice. 3. Beds of saline earths, 
found chiefly in India, but also to some extent in other 
countries. 

Physiological Actions. 

Potassa depresses the muscular, nervous, and cardiac 
tissues. Given long or in concentrated doses it destroys 
muscle and nerve tissue and nerve-centres. 

It is extremely diffusible, and is rapidly excreted, 
principally by the kidneys, but also to some extent by 
the salivary, mammary, and intestinal glands, and by 
the skin. 

In the living organism it is found chiefly in the blood 
corpuscles and muscles. 

Being so quickly removed from the body, the danger 
to the tissues, even from large doses, is comparatively 
slight, except when there is disease of the .excretory 
organs, or when it is given for a long time, and under 
these circumstances a dyscrasia or unhealthy condition 
results, characterized by impoverishment and excessive 
fluidity of the blood. 

Symptoms of Poisoning. 

In poisoning by the salts of potassa there is violent in- 
flammation of the alimentary canal ; intense burning pain 
about the epigastrium ; nausea and vomiting, sometimes 
of bloody mucus ; and profuse and watery, sometimes 
dysenteric, stools. With these there are the symptoms 
of depression of the general system : a weak, rapid 
pulse ; shrunken face ; cold skin ; coma ; and insensi- 
bility. There is sometimes paralysis of the lower limbs, 
and death may occur with great suddenness. 



THE ALKALIES AND ALKALINE EARTHS. 3 

Treatment of Poisoning. 

In potassa poisoning dilute vinegar, lemon juice, and 
cider are. given as antidotes; the stomach and bowels 
are emptied, and oils, with bland demulcent drinks, 
such as gum tragacanth, barley water, flaxseed tea, milk, 
white of egg, or gruel, given to relieve the irritation 
of the mucous membranes, and stimulants to sustain the 
heart. 



Preparations of Potassa. 

Potassii Carbonas. 
Potassium Carbonate. 

A white, granular powder, with strongly alkaline taste, 
which liquefies on exposure to the air by absorbing 
moisture from it. Dose, gr. ii.-x. (0.1-0.65 gm.) 



Potassii Bicarbonas. 
Potassium Bicarbonate. 

Sometimes called saleratus. It is not deliquescent 1 nor 
corrosive, nor as irritating as the carbonate ; otherwise 
their qualities are the same. They are antacid sto- 
machics and mild diuretics ; stimulants of the liver ; 
expectorants, and have some slight diaphoretic 
action. 

In small doses on an empty stomach they promote the 
formation of gastric juice by increasing the diffusion of 
the blood constituents from which the gastric juice is 
formed. Large doses irritate the stomach, and, taken 
during digestion, decompose the gastric juice. 

These salts are given before or after meals according to 
the effect desired. The alkalinizing action on the stom- 
ach and kidneys is more pronounced when they are 

1 Melting by absorbing moisture from the air. 



4 MATERIA MEDICA FOR NURSES. 

taken during digestion. They must be well diluted, in 
mucilaginous or sweetened water. Dose, gr. v.- 3 i. 

Liquor Potassse. 
Solution of Potassa. 

A clear, colorless liquid, strongly alkaline, made from 
potassium bicarbonate. Dose fl], ii.-xv. (= gtt. ii.-xv.), 
well diluted, (o.i-i. gm.) 

Potassa. 
Caustic Potash. 

Grayish-white pencils, hard but very deliquescent. 

Caustic potash is very powerfully corrosive. When 
applied to the skin it melts slowly, destroying the tissues 
by its affinity for moisture and power of dissolving albu- 
min. Its application is very painful and great care is 
required to avoid injury to the surrounding tissues. It 
differs from nitrate of silver in extending its action far 
below the surface ; for this reason it is used in cases 
which require deep-reaching action. The healing pro- 
cess takes place more slowly after the application of caus- 
tic potash than after that of any escharotic in use. A 
grayish slough is formed, with inflammation of the parts 
near by. The slough remains for a time varying from six 
to twelve days, when it separates, leaving a rather indolent 
ulcerated surface. 

In using caustic potash the surrounding tissues should 
be protected by adhesive plaster, having a hole cut in it 
the size of the spot to be cauterized. The surface of the 
plaster is oiled, but the oil must not touch the skin. After 
sufficient action has been obtained, and the plaster re- 
moved, the spot may be washed with dilute vinegar. 

In cases of poisoning by caustic potash, the corrosive 
action is seen about the lips and fauces in bloody oozing, 
sloughs of mucous membrane, and vomiting of shreds of 
sloughing and bloody tissue. Deformity of the mouth 
and contraction of the oesophagus and of the cardiac and 



THE ALKALIES AND ALKALINE EARTHS. 5 

pyloric orifices may remain after recovery, interfering 
mechanically with nutrition, and resulting in death after 
periods of time varying from six weeks to one or two 
years. 

Potassii Citras. 
Potassium Citrate. 

Made with citric acid and potassium carbonate. The 
least unpleasant of all the preparations of potash except 
the tartrates. It has diuretic and refrigerant diapho- 
retic action. In the blood it is decomposed, and is 
excreted by the urine in the form of alkaline carbonate. 
Dose, gr. v.- 3 ss., well diluted. (0.3-2. gm.) 

Potassii Acetas. 
Potassium Acetate. 

It is antacid, strongly diuretic, and, in large doses, 
mildly cathartic. It increases the flow of urine and 
diminishes the secretion of urea and uric acid. Dose, 
gr. x.-3 i., largely diluted. {0.65-4. gm.) 

• 

Potassii Chloras. 
Potassium Chlorate. 

The powder is white, odorless, with a cool, salty taste. 
It is not deliquescent. In combination with organic 
matters it is explosive. Soluble in 16 parts of cold and 
2J parts of boiling water. 

Physiological Action. 

Potassium chlorate acts as a stimulant to mucous mem- 
branes and ulcerated surfaces, and its use as an applica- 
tion for sore throat is familiar. In medicinal doses it has 
no marked effect upon the system, but taken continuously 
it is very irritating to the kidneys, and causes chronic 
nephritis or inflammation of those organs. 



6 MATERIA MEDIC A FOR NURSES. 

This fact is not very generally understood among non- 
professional people, and potassium chlorate is used to 
excess by numbers of persons, without the authority of a 
physician, under the impression that it is perfectly harm- 
less. A nurse has many opportunities of observing 
habits of this kind, and should use all her influence to 
discourage them. Potassium chlorate is eliminated un- 
changed by the urine. 



Symptoms of Poisoning. 

Taken in sufficient quantities potassium chlorate is 
a powerful poison and has often caused death. The 
symptoms may be acute or subacute. In the former 
case there are violent vomiting, profuse diarrhoea, and 
great dyspnoea and cyanosis. After death, which occurs 
from heart failure, the blood is of a chocolate color. In 
subacute cases there are severe gastro-intestinal symp- 
toms ; vomiting of blackish-green matters and swelling 
of the liver and spleen. The urine is albuminous, dimin- 
ished, and sometimes suppressed. Its color is dark, 
reddish brown, or black, and under the microscope the 
detritus of red blood corpuscles, which had choked the 
tubules of the kidney, may be seen. The nervous symp- 
toms are headache, loss of appetite, great pains in the 
abdomen and other parts of the body, marked abdominal 
tenderness, tonic and clonic cramps, a peculiar stiffness 
of the extremities, delirium, and coma. Small ecchy- 
moses sometimes appear on the surface of the body, 
and there is frequently a general jaundice. In some 
cases there is a fatal relapse after the patient seems in a 
fair way to recover. The smallest poisonous dose is not 
known, but in one case death was caused by a little over 
5 ss. A child one year old died from 3 i. given in a 
night, and a child of three years from 3 iii- In one case 
death took place a week after taking f i. 

Dose, gr. x.-xxx., well diluted. (0.65-2. gm.) 



THE ALKALIES AND ALKALINE EARTHS. *] 

Potassii Cyanidum 
Potassium Cyanide. 

It has the odor of hydrocyanic acid and similar though 
somewhat alkaline taste. It is soluble in water. When 
taken into the stomach the acids there convert it into 
hydrocyanic acid. 



Physiological Actions. 

The physiological, therapeutic, and toxic effects of this 
salt are like those of hydrocyanic acid. Death, how- 
ever, does not occur so soon, and insensibility is some- 
times not manifested for several minutes. Cases of 
poisoning have occurred from inhalation of the vapor ; 
also from absorption through the hands, among photogra- 
phers. There is, usually, little time to employ treatment. 
A weak solution of sulphate of iron has the effect of 
decomposing the poison and converts it into Prussian 
blue. Cold affusions and other treatment, the same as 
used for hydrocyanic-acid poisoning, may be tried. 
Death has been caused by gr. v. 

A solution of potassium cyanide, in the strength of 2 
to 4 grains in § i. of water, will remove" the stains of 
nitrate of silver. 

Dose, gr. yV-rV (0.006-0.005 gm.) 

Potassii Bitartras. 
Potassium Bitartrate. 
Cream Tartar. 

Made from argol, and from lees of wine by purifica- 
tion and evaporation. White crystalline masses of 
pleasant acid taste, not readily soluble in water, requir- 
ing for solution in cold water about 180 parts, or more. 
An active diuretic and hydragogue cathartic. It 
is agreeably given as "cream of tartar lemonade." The 
quantity ordered is dissolved in hot water, and when 



8 MATERIA ME DIC A FOR NURSES. 

cool, the clear solution is poured off, flavored with lemon 
juice, and sweetened to taste. In excessive doses it will 
produce gastro-intestinal troubles, and one case of 
poisoning is recorded after taking over | ss. 

Potassii Nitras. 
Potassium Nitrate. 
Saltpetre. 

Obtained for medicinal use chiefly by purification of 
native nitre found in beds of saline earths in India. 
It is also found in saltpetre caves in the United States, 
and is manufactured artificially in nitre beds formed 
of animal and vegetable matter, wood ashes, and cal- 
careous earth ; and, finally, is obtained from old plaster 
rubbish. 

Nitre is refrigerant, diaphoretic, diuretic, and in 
large doses laxative. In excessive or concentrated 
doses it may act as a fatal poison, producing gastro- 
enteritis and derangement of the nervous system. 



Symptoms of Poisoning. 

Burning pain in throat and stomach ; bloody stools ; 
syncope ; collapse and death, sometimes preceded by 
convulsions. Death has been caused by | i., but when 
in weak solution much larger quantities may be safely 
taken than would cause death if concentrated. There is 
no known antidote. Mucilaginous drinks should be 
given, vomiting freely promoted, and the stomach-pump 
used. 

Dose, gr. ii.-x. well diluted with barley water or other 
demulcent. (0.1-0.65 gm.) 

Potassii et Sodii Tartras. 
Potassium and Sodium Tartrate. 
Rochelle Salt. 

Made by adding carbonate of soda to a solution of 
potassium bitartrate. A mild saline purgative, less effi- 



THE ALKALIES AND ALKALINE EARTHS. O, 

cient but less offensive to the taste than Epsom salt. It 
is given very hot or very cold, in a saturated solution. 
If given in hot water, the addition of tr. ginger, gtt. x - 
xv , makes it more agreeable to the taste. If cold, 
it may be- given in seltzer or carbonated water. It 
should be given early in the day and on an empty 
stomach. 

Soda (Soda). 

There are four natural sources of the official salts of 
soda and their preparations, viz. : 
i. Sodium, a metallic element. 

2. Sodium chloride, or common salt, obtained from 
sea-water by evaporation and from salt mines. 

3. Sodium nitrate. Found native in Chili and puri- 
fied by crystallization from water. 

4. Sodium borate or borax ; a native product found 
in various localities. 

Physiological Actions. 

The salts of soda are absorbed into the blood and 
excreted from it more slowly than the salts of potassa, 
and for this reason the action of soda upon the alimen- 
tary canal is stronger than that of potash. It is diuretic, 
but not as strongly so as potash ; antacid, and purga- 
tive. It is less depressing than potash and more 
easily borne by the stomach. The soda salts are 
taken into the organism in large quantities with food, 
especially vegetables and fruits, and are the chief source 
of the natural alkalinity of the blood. Soda is excreted 
by all the mucous surfaces, by the kidneys, the liver, and, 
possibly, by the skin. 

Sodii Chloridum. Sodium Chloride. 
Common Salt. 

Salt performs a very important part in the human 
economy. It exists normally in the blood in the propor- 
tion of 4 to 1000, and is very abundant in various normal 



io materia medic a for nurses. 

secretions. Active tissue changes are promoted by the 
presence of salt. It stimulates the desire for food, and 
aids in its thorough alteration and absorption. It is the 
natural antiseptic of the blood ; aids osmosis, 1 and keeps 
the fibrin and albumin of the blood in solution. Water 
alone is injurious to cut tissues, but a weak solution of 
salt makes it non-irritant. During the course of an 
inflammation sodium chloride, being needed for its 
solvent action, accumulates in the inflamed area, disap- 
pearing temporarily from the urine. This is notably the 
case in pneumonia, and the return of the chloride to the 
urine marks a favorable change in the condition of the 
patient. In substance or in strong solution it is irritat- 
ing to cut surfaces, mucous membranes, muscle and 
nerve tissue. Taken into the stomach in large quantities 
it causes vomiting, and when absorbed in excess of the 
needs of the system it causes the nervous irritation which 
produces the sensation of thirst, and which is relieved by 
taking enough water to dissolve the salt and carry it 
away to be excreted by the kidneys. Salt dissolves in 2f 
parts of water. 

In convalescence patients often crave some salty arti- 
cle of food which, being indigestible, must be denied 
them, but the need of the system which is thus expressed, 
may be satisfied by giving salt in another way. 

In feeding babies and young children a pinch of salt 
should always be added to the milk, as its action opposes 
the formation of hard curds in the milk. 

Salt water in strong solution is an anthelmintic. 

» 
Sodii Carbonas. Sodium Carbonate. 

Called sal soda, or washing soda. Transparent color- 
less crystals, soluble in two parts of water Its effects 
are similar to those of the potassium carbonate, but 
it is rarely used medicinally. In large quantities it is 



1 The force by which fluids pass through moist membranes. 



THE ALKALIES AND ALKALINE EARTHS. II 

an irritant poison for which oils and acids are the 
antidotes. It is an excellent material for cleaning 
glass, china, and wood. Poured in strong solution 
into drains and water-pipes it carries away grease. It 
will remove the stains made by bichloride of mercury 
on china and glass. 

Sodii Bicarbonas. 
Sodium Bicarbonate. 

Soluble in 12 parts water (saturated solution). So- 
dium bicarbonate has a soothing action in burns, erup- 
tions, and irritation of the skin. Dose, as an antacid, 
gr. x.-xx. It is pleasantly administered in carbonated 
water — Seltzer or Vichy. (0.65-1.3 gm.) 

Pulvis Effervescens Compositus. 
Compound Effervescing Powder. 
Seidlitz Powder. 

Seidlitz powder is put up in two packets, a white paper 
containing gr. xxv. of tartaric acid (the acid of grapes), 
and a blue one containing gr. xl. of sodium bicarbonate 
and gr. cxx. or 3 ii- of Rochelle salt. They are dis- 
solved separately in very cold water, the acid in one or 
two ounces, and the salt in five or six. They are then 
poured together and taken after the first escape of gas, 
while still effervescing. It is hardly necessary to say 
that they should not be mixed at a distance from the 
patient, but at his side and at the precise moment when 
he is ready to take the dose. The glass must be large, to 
allow for the effervescence, and it is well to have a saucer 
under it, to avoid the annoyance of having it effervesce 
over the top and sides. The powders must be kept dry. 
Exposed to the air they become damp and lose their 
effervescing quality. Seidlitz powder is refrigerant and 
laxative, and should be given in the morning on an 



12 MATERIA MEDIC A FOR NURSES. 

empty stomach. One powder is usually sufficient for a 
dose, acting in from three to six hours. 

Sodii Boras. Sodium Borate. 
Borax. 

Borax is found as a native product in several localities. 
It is also artificially made by combining native boric acid 
with soda. On the skin it acts as a soap — removing the 
epidermis. Added to " hard " water, it softens it pleas- 
antly for bathing purposes, and is useful in many local 
and external applications by means of its cleansing 
properties. 

Lithium. 

Lithium is obtained from several minerals, and traces 
of it are found in certain mineral waters. 

Lithium salts have strong alkaline properties, and act 
on the human organism as do the other members of the 
group. It is stated that lithium salts alkalinize the 
urine more decidedly even than salts of potassium. 

Preparations. 

Lithii Carbonas. Lithium Carbonate. Dose, gr. ii.-x. 

(0.1-0.65 gm.) 
Lithii Citras. Lithium Citrate. Dose, gr. v.-x. (0.3-0.65 gm.) 
Lithii Benzoas. Lithium Benzoate. Dose, gr. ii.-xv. 
Lithii Salicylas. Lithium Salicylate. Dose, gr. v.-xv. 

Ammonia (Ammonia). 

Ammonia is a gaseous compound of hydrogen and 
nitrogen ; colorless, irrespirable, highly irritant, of strong 
alkaline reaction and pungent odor. It is obtained in 
the manufacture of coal gas, and occurs as a result of 
the decay of organic substances. 

Physiological Actions. 

Applied to the skin, ammonia is a powerful irritant, 
causing redness, blistering, and sloughing. Inhaled, it 
causes severe irritation of the air-passages, with sneezing, 



THE ALKALIES AND ALKALINE EARTHS. 1 3 

disturbed respirations, flow of water from the eyes and 
nose, and quickened pulse. Ammonia acts as a general 
Stimulant to the heart and nervous system, especially 
the spinal cord and respiratory centre. Being rapidly 
diffused, its action is prompt but somewhat transitory. 
It is excreted by the kidneys and mucous membranes. 

Symptoms of Poisoning. 

In large amount ammonia is a corrosive poison, pro- 
ducing violent abdominal pain, vomiting and purging of 
bloody matters, with convulsions, collapse, and death. 
Consciousness may remain until the last, or coma may 
precede death. In some cases death has taken place 
within five minutes, having been caused probably by 
cedema of the larynx. The symptoms come on at once 
in poisoning by ammonia. 

Treatment of Poisoning. 

Dilute vinegar or lemon juice are given to counteract 
the alkali ; oils and bland liquids to soothe the mucous 
membrane, which is corroded. Heat favors the action 
of ammonia, and cold antagonizes it ; therefore, in pois- 
oning by ammonia plenty of cold fresh air should be 
admitted, if possible, and cold applications made to the 
head. The feet must be kept warm. 

Preparations of Ammonia. 

Ammonii Chloridum. . 
Ammonium Chloride. 

Made by neutralizing ammoniacal gas liquor with hydro- 
chloric acid, evaporating, and purifying. The action of 
ammonium chloride on the skin is soothing rather than 
irritating, as applied in lotions. It has a cooling effect, 
and is a tonic to the sensory nerves, and reduces local 
external inflammation. It has a Stimulant action on the 
liver ; is diuretic and diaphoretic, and, like other 
preparations of ammonia, a stimulant expectorant. 
The taste is very nauseous, resembling sea-water. 

Dose, gr. v.-xx., well diluted with cold water. (0.3- 
i.3 g m -) 



14 MATERIA MEDICA FOR NURSES. 

Ammonii Carbonas. 
Ammonium Carbonate. 

A very active and quickly diffusible Stimulant to the 
heart and respiration, and an expectorant, acting in 
the latter capacity by liquefying the bronchial secretions, 
which are thus more easily raised, and the air-cells kept 
free. In large doses (gr. xxx.) ammonium carbonate acts 
as an emetic. It has a nauseous taste, is very pungent, 
and must be well diluted. It may be given in milk. 

Dose, gr. v.-x. (0.3-0.65 gm.) 

Aqua Ammoniae Fortior. 
Stronger Ammonia Water. 

Has a strength of 26 per cent., and has been used as 
an application to the bites of poisonous animals or 
serpents. It may be used as a vesicant, but its action 
is apt to be more severe than is desirable. It acts more 
quickly than cantharides, and does not affect the urinary 
organs. 

Aqua Ammoniae. 
Ammonia Water. 

A solution of the gas in water, 10 per cent, in strength, 
It may be used externally as a counter-irritant. Ap- 
plied in dilute solution to the bites made by insects, it 
relieves the sting. Taken internally, it is a general 
stimulant and antacid. 

Dose, TTi v.-xxv. (lU x. = gtt. x.), largely diluted. 
(0.3-1.6 gm.) 

Spiritus Ammoniae Aromaticus. 
Aromatic Spirit of Ammonia. 

Contains ammonia water, and 4 per cent, of the car- 
bonate, with oil of nutmeg, of lemon, and of lavender ; 
alcohol and water. It is an antacid and stomachic, over- 
coming a feeling of nausea, and a general stimulant. It 
is not unpleasant. 

Dose, 3 ss.- 3 i. {y\, x. = gtt. xxv.), well diluted in 
milk or water. (2.-4. gm.) 



THE ALKALIES AND ALKALINE EARTHS. 1 5 

Liquor Ammonii Acetatis. 
Solution of Ammonium Acetate. 
Spirit of Mindererus. 

Made from carbonate of ammonia and acetic acid. It 
is more active than the other preparations, as a dia- 
phoretic, especially if the body be kept warm. If the 
skin be kept cool, its diuretic action is more pro- 
nounced. It is also a nervous stimulant. Dose, 3 i.- 
3 iv., well diluted with water. (4.-32. gm.) 

Linimentum Ammoniae. 
Ammonia Liniment. 

A mixture of ammonia water with alcohol and cotton- 
seed oil. It should be freshly made. 
Raspail's Sedative Water. 

A mixture of ammonia water, sodium chloride, and 
camphorated spirits of wine, with water. For sponge 
baths ; cooling and sedative. 

Calcium (Lime). 

Lime is obtained from four sources : 1, Chalk. 2. 
Marble. 3. Native sulphate, or plaster-of-Paris. 4. 
Bone-ash. Lime is an exceedingly important constituent 
of the body, being found, in the form of solution of 
phosphate of lime, in every animal tissue and fluid. It 
gives solidity to bones, and accumulates wherever rapid 
tissue changes are taking place. The preparations of 
lime are antacid and slightly astringent. Locally 
they are sedative to mucous membrane. Lime is a 
valuable antidote in poisoning by oxalic acid, chloride 
of zinc, and the mineral acids. It can always be obtained 
for this purpose in the form of wall-plaster or whitewash. 

Preparations of Calcium. 

Calx. 
Lime. 

Made from chalk or limestone by calcining (purifying 
and rendering friable by the action of heat). In this 
state it has the form of compact white masses, which 



1 6 MATERIA MEDIC A EOR NURSES, 

readily absorb water, crack, evolve heat, and fall into 
powder. It is then called slaked lime, or quick-lime. 
If it should come in contact with the eye, it should be 
washed out with a solution of boric acid. 

Liquor Calcis. 
Lime-Water. 

Lime-water is a saturated solution of lime containing 
about f of a grain to § i. of water. It is made by wash- 
ing slaked lime and shaking it up in distilled water, 
preferably, though ordinary water may be used. After 
it settles, the water is poured off from the sediment and 
strained. It is colorless, inodorous, and has a disagree- 
able alkaline taste. By exposure to the air it absorbs 
carbonic acid, and should therefore always be kept well 
corked. Lime-water acts as a gastric sedative, and 
added to milk prevents its curdling in large lumps. The 
ordinary proportion is lime-water | ss. to milk § v., in- 
creased, according to circumstances, to -J or even \ lime- 
water. Lime-water is slightly constipating. 
Milk of Lime. Whitewash. 

To one part of slaked lime, as above, four parts of 
water are added. This, mixed thoroughly with infectious 
stools, and added until the mixture gives a strong alka- 
line reaction when tested with litmus paper, is considered 
the most efficient disinfectant for cholera and typhoid 
stools. Next to it in value comes chloride of lime, 
which is not effective unless fresh. This is to be made 
in a solution of six ounces to one gallon of water. 

Syrupus Calcis. 
Syrup of Lime. 

Five parts of lime to one hundred parts syrup. Dose* 

3i. (4- gm.) 

Linimentum Calcis. 
Lime Liniment. 
Carron Oil. 

A mixture of lime-water and olive oil or linseed oil, in 
equal parts, for external use. It is an excellent appli- 
cation for burns, and has the merit of cheapness. 



THE ALKALIES AND ALKALINE EARTHS. 1 7 

Creta Praeparata. 
Prepared Chalk. 

Made from chalk by a cleansing and drying process. 
A smooth white powder, insoluble in water, and of as- 
tringent -action. Externally, it is used as a dusting- 
powder. When taken internally it may be administered 
in glycerine or syrup. Dose, gr. v.- 3 i. (°-3 - 4- g m -) 

Mistura Cretae, 
Chalk Mixture. 

Contains prepared chalk gr. xxx. to f i., and is an 
astringent. Dose, 3 i - ? ss. (4 ~3 2 - g m -) 

Magnesia (Magnesia). 

The officinal preparations of magnesia are all derived, 
directly or indirectly, from the sulphate. 

Physiological Actions. 

Magnesia, in the form of the oxide and carbonates, 
forms insoluble and comparatively harmless compounds 
with the mineral acids. It is therefore used as an anti- 
dote for these poisons, the oxide being preferable, and to 
be very freely given. 

Magnesia has antacid, purgative, and diuretic 
qualities. Entering the circulation, it increases the al- 
kalinity of the plasma, and is partly excreted by the 
kidneys, rendering the urine more abundant and less 
acid. 

Preparations of Magnesia. 

Magnesii Sulphas. 
Magnesium Sulphate. 
Epsom Salt. 

Made from dolomite, or magnesian limestone, by solu- 
tion in sulphuric acid and purification. A quickly acting 
hydragogue cathartic, easily borne by the stomach, 
though of nauseous taste. Ordinary laxative doses act 
in a few hours. Large doses ( § i.-ii.) produce a result 



1 8 MATERIA MEDIC A FOR NURSES. 

almost immediately, and cause griping and abdominal 
distension. It should be given well diluted and on an 
empty stomach. It is soluble in 2J parts of water. 
Dose, § ss., in carbonated, Seltzer, or Vichy water. 

Liquor Magnesii Citratis. 
Solution of Magnesium Citrate. 

In small does a laxative, in large ones cathartic, 
acting in from four to six hours. It is effervescent, and 
should be kept cold and taken at the moment it is poured 
out. If the whole amount is not taken at once the bot- 
tle should be stood on the corked end or laid on its side. 
Dose, § iv.-vii. 

Magnesii Citras Effervescens. 

Effervescent Magnesium Citrate (Citrate of Magnesia). 

A white coarse-grained salt of refreshing taste, very 
soluble and effervescent, acting in the same way as the 
liquor. 

Dose, 3 i.-iv. stirred up in cold water. (4-~3 2 - g m -) 

Cerium (Cerium). 

A metal of which the oxalate only is used. 

Cerii Oxalas. 
Cerium Oxalate. 

A white granular powder, insoluble in water, alcohol 
or ether. It is a gastric sedative, and is given dry or 
the tongue. Dose, gr. i.-v. (0.06-0.3 g m -) 

THE METALS. 

Plumbum (Lead). 

Lead is found native in small masses. It is a dull, 
whitish metal with a tint of blue, and is not given in its 
native state, medicinally, but in the form of salts. 



THE METALS. 1 9 

Physiological Actions. 

The special property of the lead salts is astringency, 
and they are, in consequence, sedative, anti-phlogis- 
tic, and haemostatic. 

Used in dilute solutions externally as applications to 
ulcers, mucous surfaces, etc., they precipitate the albumi- 
nous fluids which cover the surface, contract the small 
blood-vessels, and harden the tissues of the young grow- 
ing cells. Applied in concentrated solutions, they are 
irritant, causing inflammation, or increasing it. Taken 
internally, their action is first evident as a peculiar as- 
tringent taste, with a dry feeling of the throat. In the 
stomach and intestines the same action is shown. Lead 
dries the secretions, contracts the vessels, and checks 
peristaltic action, thus causing constipation. 

It is changed by the intestinal juices into an albuminate, 
and so enters the blood. It is rapidly deposited in the 
tissues, especially in the central nervous system, the kid- 
neys, liver, and bones. It is excreted, but slowly, in the 
bile, the urine, and perspiration ; also by the mammary 
glands. It diminishes the excretion of uric acid by the 
kidneys. 



Poisoning by Lead. 

Acute lead poisoning is rare, and will be spoken of in 
connection with the acetate. Chronic poisoning is quite 
common, the poison being introduced into the system in 
one or more of the following ways : By absorption 
through the unbroken skin, as in the case of painters, 
glaziers, etc. — the fine particles of metal which are rubbed 
off and adhere to the skin being changed by its secre- 
tions into soluble salts which are readily absorbed ; by 
absorption through ulcers, wounds, etc., from the exces- 
sive application of ointments ; by the use of food put up 
in cans soldered with lead, cooking utensils made of 
painted wood or imperfectly burnt pottery, and by eating 
buns, cake, etc., colored with chromate of lead ; by the 



ZO MATERIA MEDIC A FOR NURSES. 

habit of biting silk thread adulterated with lead ; by 
sleeping or working in newly painted rooms,. and by the 
poisoning of a water supply from lead pipes. This 
does not occur with " hard " water — viz., that contain- 
ing salts of lime, as an insoluble coating is then deposited 
on the lining of the pipes ; but with pure, or " soft " 
water, the lead is slowly dissolved in the form of a car- 
bonate. The first symptoms of poisoning are : A feeling 
of pain, with a sense of sinking in the region of the 
navel ; loss of appetite, thirst, and dryness of the mouth 
and throat, with a metallic astringent taste ; pale face 
and skin generally ; fetor of the breath ; constipation ; 
emaciation and wasting of the muscles, especially those 
of the arms ; swelling of the joints, and rheumatic pains. 
Colic is a very pronounced symptom, sometimes coming 
on very suddenly, sometimes after several days' illness. 
The pain is intense and varies in character, sometimes 
being sharp, sometimes dull, or, again, " twisting," and 
seems to centre about the umbilicus. This fact of its 
being localized differentiates it from hepatic colic, which 
goes through to the back, and from renal colic, which 
radiates along the line of the ureters. The abdominal 
walls are violently retracted and rigid, and neuralgic 
pains seize the abdominal muscles and shoot along those 
of the thorax and extremities, especially the flexors. The 
skin and conjunctivae sometimes become jaundiced, and 
the urine tinged with bile. 

A very striking feature of lead poisoning, occurring 
both in acute and chronic cases, is the dark slate-colored 
line on the gums along the margin of the incisor teeth. 
It is said to be more marked in those cases where the 
tooth-brush is not used. 

The chronic nervous symptoms of lead poisoning may 
be developed after the first attack of colic, or they may 
come on without marked abdominal disturbance. The 
most common and noticeable one is the paralysis of 
the extensor muscles of the forearms, causing what is 
termed " wrist-drop." With this there is sometimes 
either partial or complete anaesthesia of the affected 
members. 



THE METALS. 21 

Paralysis of the laryngeal muscles sometimes occurs, 
resulting in aphonia. The pulse is incompressible and 
tense, full, and infrequent. There may be anaesthesia of 
the optic nerve, as a result of the direct action of lead, 
or dimness of sight may result from the albuminuria, 
which is often present ; and, finally, there may be a con 
dition of cerebral disturbance known as " encephalopatliia 
saturnina," or lead encephalopathy, beginning with head- 
ache, and characterized by delirium, stupor, epileptiform 
convulsions, and coma. Death may follow, although 
severe cases have been known to recover. Death may 
also result from the gradual failure of nutrition, or from 
an extension of paralysis to the muscles of respiration. 



Treatment of Poisoning. 

In treating chronic lead poisoning, large doses of 
purgatives are given Potassium iodide aids in elimina- 
tion of the poison, and baths of potassium sulphide are 
also used for this purpose. Workers in lead may guard 
against poisoning by personal cleanliness, which is of 
great importance, by the use of sulphuric-acid lemonade, 
and milk, as a food, in large quantities. 



Preparations of Lead. 

Plumbi Acetas. 
Lead Acetate. 
Sugar of Lead. 

Made by the action of acetic acid on litharge, or lead 
oxide. This is the only preparation of lead given inter- 
nally. Acute poisoning has been caused by the lead 
acetate, although, as it acts as an emetic, it is rarely fatal. 
The symptoms appear in from half an hour to two hours 



22 MATERIA MEDIC A FOR NURSES. 

after taking it, and are essentially the same as described 
under chronic poisoning Recovery may take place 
within a few days, although symptoms recur, occasion- 
ally, after a long interval. The fatal dose is between 
§ i. and ii. The treatment consists of large doses of 
Glauber's and Epsom salts ; castor oil ; emetics, if vom- 
iting is not already excited ; opium ; and albuminous 
drinks freely given. 

Dose, gr. ii.-v., always in pill. 

Liquor Plumbi Subacetatis. 
Solution of Lead Subacetate. 
Goulard's Extract. 

Used only externally. It should be diluted, in a 
strength of J i.-iv. to O i. of water. 

Ceratum Plumbi Subacetatis. 
Cerate of Lead Subacetate. 
Goulard's Cerate. 

Composed of white wax, olive oil, camphor, and Gou- 
lard's extract. For external use. 

Emplastrum Plumbi. 
Lead Plaster. 
Diachylon Plaster. 

Made with lead oxide, olive oil, and water. 

Emplastrum Resinae. 
Resin Plaster. 
Adhesive Plaster. 

Made of resin, lead plaster, and yellow wax. 

Emplastrum Saponis. 
Soap Plaster. 

Made of soap, lead plaster, and water. 

Unguentum Diachylon. 
Diachylon Ointment. 

Made of lead plaster, olive oil, and oil of lavender. 



THE METALS. 27, 

Argentum (Silver). 

The metal silver itself is not used in medicine, and its 
preparations are not numerous. The properties of silver 
will be described under its most important salt. 

Argenti Nitras. 
Silver Nitrate. 

Prepared by dissolving silver in nitric acid. 

Physiological Actions. 

Silver nitrate has locally a caustic Or corrosive 
action. It combines with the albumin of the tissues, 
forming a superficial slough. It has a strong metallic 
and styptic taste, and in the stomach produces a feeling 
of warmth. It is decomposed by the gastric juice, and, 
therefore, does not act as an irritant to the stomach, 
unless taken in poisonous doses. Silver enters the blood 
as an albuminate, and, if continued for some time, a part 
of it remains permanently in the connective tissues, 
staining them a dull slate-gray, which cannot be removed. 
This tinge first appears as a line along the gums and 
teeth, and on the mucous membrane inside the lips and 
cheeks. In small doses silver is astringent and anti- 
spasmodic, Stimulates secretion and nutritive pro- 
cesses, and is a nerve tonic. Long continued it 
disorders digestion, and produces a general waste of 
tissue, albuminuria, rapid and irregular heart action, 
disturbed respiration, and nervous symptoms, viz. : te- 
tanic convulsions, loss of the power of co-ordination, 
and paralysis. 

Symptojns of Poisoning. 

In toxic doses silver causes gastro-enteritis, and the 
antidote is common salt, given very freely in solution. 
It forms an insoluble chloride, and also acts as an 
emetic. 



24 MATERIA MEDICA FOR NURSES. 

Preparations of Silver. 

Dose of the nitrate, gr. J-J, 1 in pill, given after meals, 
unless otherwise ordered. Silver nitrate is quickly 
decomposed, if in solution, by organic matter and by the 
action of light, and is for that reason kept in dark-colored 
bottles, and should never be left uncorked. With tannin 
it forms an explosive compound. 

Argenti Nitras Fusus. 
Silver Nitrate. 
Lunar Caustic. 

Made by evaporating silver nitrate and forming it in 
pencil-shaped moulds. It is used externally as a caustic. 
It is not deliquescent ; its action is superficial and does 
not extend beyond the point touched ; and the slough 
formed is rapidly healed. In applying silver nitrate the 
pencil should always be washed in an antiseptic solution 
before and after using, and especially before it is put 
away, carefully dried. 

Argenti Nitras Dilutus. 
Diluted Silver Nitrate. 
Mitigated Caustic. 

Made with silver nitrate and potassium nitrate. For 
local use externally, and is used as an application to 
the eyelids. 

Aurum (Gold). 
Preparations of Gold. 

Auri et Sodii Chloridum. 
Gold and Sodium Chloride. 

This salt is a somewhat deliquescent powder of salty 
metallic taste, soluble in water. The precise physiologi- 
cal action of the salts of gold are not well understood. 
Clinically the gold preparations are looked upon as alter- 
atives and nerve tonics, improving general nutrition, and 
more especially the nutrition of the nervous system. 
The most prominent use of gold is in connection with 

1 (0.015 — 0.03 gm.) 



THE METALS. 2$ 

the alcohol habit. It is believed that in the Keeley insti- 
tutes for the cure of alcoholism the treatment consists in 
part at least of the gold and sodium chloride, with inter- 
vening doses of strychnia and atropine. 

The dose in solution or pill form is gr. -j^-J. (0.006 
-0.02 gm.) Hypodermically it is irritating and painful. 

Auri Chloridum. 
Gold Chloride. 

It is claimed that this salt is useful in lupus and other 
tubercular diseases. Dose, gr. T ^. (0.00043 gm.) 

Auri et Potassii Bromidum. 
Gold and Potassium Bromide. 

This drug is used in the treatment of epileptic condi- 
tions. It is usually given hypodermically. Unpleasant 
symptoms referable to the cardiac region may be caused 
by it, as pain and rigor, but they do not last long. Dose, 
gr. -H|. (0.02-0.04 gm.) 

Zincum (Zinc), 

There are two sources of the salts and preparations of 
zinc, viz. : the metal, zinc, and the native carbonate, 
calamine. 

Physiological Actions. 

The salts of zinc are, in their stronger forms, caustic ; 
in weaker forms, astringent and antiphlogistic. The 
activity of the different preparations is in proportion to 
their solubility and diffusibility. Applied to a broken 
surface or mucous membrane, the salts of zinc harden 
the albuminous secretions, check the growth of new 
cells, and contract the vessels, though in a lesser degree 
than do lead and silver. The salts of zinc, in the blood, 
take the form of albuminates. They enter the circula- 
tion slowly, do not have the tendency to accumulate and 
remain fixed in the tissues as do lead, mercury, and 
copper, and are much more rapidly excreted. They are 
eliminated by the liver, kidneys, intestinal and mammary 
glands. 



26 MATERIA MEDIC A FOR NURSES. 

Symptoms of Poisoning. 

If the use of zinc be long continued there may result a 
series of symptoms similar to those of lead-poisoning, 
though less severe — viz., wasting of the tissues and loss 
of strength ; pallor ; muscular weakness and trembling ; 
colic ; fetid breath and constipation ; feeble mind ; and 
paralysis. 

Treatment of Poisoning. 

In cases of acute poisoning by zinc salts the antidotes 
are lime-water, tannin, in the form of strong tea, carbo- 
nate of sodium or potassium, soap-suds, and mucilaginous 
drinks, milk, etc. Vomiting should be encouraged and, 
if necessary, the stomach washed out. 

Preparations of Zinc. 

Zinci Chloridum. 
Zinc Chloride. 

Made by dissolving zinc which has been melted and 
poured into cold water, in dilute hydrochloric acid, and 
boiling. It then goes through several purifying pro- 
cesses. A whitish - gray, deliquescent substance, soft, 
like wax, and with very corrosive and irritant action. 
It is used as a caustic and acts powerfully, causing 
destruction of the part, with severe pain, followed by 
sloughing which heals slowly. An impure solution 
known as Burnett's fluid, containing 200 grains to § i. of 
water, is sold as a disinfectant and has caused numerous 
cases of poisoning. The symptoms, which are those of 
severe gastro-enteritis and collapse, come on immedi- 
ately, and death may result in a few hours, or be delayed 
for several days. 

Zinci Sulphas. 1 
Zinc Sulphate. 

Made by dissolving zinc in dilute sulphuric acid, and 
crystallizing. Soluble in water. In small doses sulphate 

1 Zinc solution for the disinfection of white clothing. Sulphate of 
dnc, § ii. Common salt, § iv. Water, 1 gallon. Soak clothes for 
4 to 6 hours, boil, and wash. 



THE METALS. 2J 

of zinc has tonic and astringent properties. Contin- 
ued long in medicinal doses it may cause ulceration 
of the mucous membrane of the alimentary canal. 
Zinc sulphate is a specific emetic. It acts promptly 
and entirely by its local irritant action, not being 
absorbed, and causing no flow of secretions. It is not 
constitutionally depressing, and causes but little nausea 
either before or after the act of vomiting. 

Dose (medicinal), gr. iV~i. (0006-0.06 gm.) 
Dose (emetic), gr. xv.-xx. largely diluted with warm 
water, and given every fifteen minutes until vomiting 
occurs. (1.-1.3 gm.) 

Zinci Oxidum. 
Oxide of Zinc. 

A yellowish white powder, insoluble in water, and used 
principally to dust over the skin as an astringent. 
Sometimes used as an astringent internally. 

Dose, gr. ss.-v. (0.03-0.3 gm.) 

Unguentum Zinci Oxidi. 
Zinc Ointment. 

Made of oxide of zinc, usually twenty parts, to ben- 
zoinated lard — eighty parts. 



Cuprum (Copper). 

The action of copper is very similar to that of silver 
and zinc. Metallic copper is inert. The salts are not 
absorbed by the unbroken skin, but applied to mucous 
membranes and exposed tissues they are caustic, 
Stimulant, and astringent. Internally in small doses 
they have the two latter, and also tonic, qualities ; and 
in large doses act on the stomach as irritants, causing 
vomiting, and on the intestines as irritant purgatives. 
Copper salts enter the blood very slowly, and are elimi« 
nated by the saliva, bile, faeces, and urine. 



28 ' MATERIA MEDICA FOR NURSES, 

Preparations of Copper. 

Cupri Sulphas. 
Cupric Sulphate. 
Copper Sulphate. 



Sometimes called blue vitriol, or Milestone. 
Externally it is used as an escharotic, and internally 
as a tonic and astringent. 

Symptoms of Poisoning. 

In cases of acute poisoning by blue vitriol, as much 
as | ss. or upwards, will produce the following symp- 
toms, which come on in a few minutes : A strong 
metallic taste in the mouth ; nausea, and vomiting of 
bluish or greenish liquids ; a feeling of constriction in 
the throat ; a distended abdomen ; colicky pains in 
the stomach and bowels ; diarrhoea and tenesmus. 
These symptoms are fully developed in one or two 
hours : then follow rapid and difficult breathing ; small, 
quick, pulse ; great thirst ; cold perspiration ; weak' 
ness giddiness, stupor, coma, convulsions, and paral- 
ysis. Death may occur in a few hours, or delay several 
days. 

Treatment of Poisoning. 

Albumin, as white of egg, milk, wheat flour, should be 
given, and then, as the albuminate of copper is not en- 
tirely harmless, the stomach should be well washed out 
with plenty of warm water. Stomach-pump used if 
necessary. The chemical antidote is potassium ferro- 
cyanide, but with this, too, emesis should follow 
promptly. 

Dose (medicinal), gr. T V~ }. (0.004-0.015 gm.) 

Dose (emetic), gr. vi.-xii. (0.3-1. gm.) 



THE METALS. 29 

Copper poisoning, acute and chronic, may result from 
the use of dirty copper dishes and cooking utensils, and 
from cooking acid fruits in copper. Chronic poisoning 
is also caused by the inhalation of the fumes of copper, 
as in certain occupations, and by the adulteration of 
certain articles of food, as pickles, which are sometimes 
colored green with copper. Chronic poisoning presents 
the same symptoms as the acute form, but in a lesser 
degree, and death may result from exhaustion. 



Alumen (Alum). 

Alum has a crystalline form and taste which is both 
acid and sweetish, and also astringent. It is soluble 
in water, but insoluble in alcohol. 

Physiological Actions. 

Alum is an astringent and styptic. In doses of 
3 i. it is an irritant but non-depressing emetic, and in 
large doses a purgative. Taken into the mouth, the 
flow of saliva is first increased by alum, and afterwards 
diminished, as it hardens the albumin of the secretions 
and contracts the capillaries. 

The same effect is shown on the mucous membrane 
of the stomach. Alum is absorbed into the blood, 
notwithstanding its power of coagulating albumin, and 
checks capillary hemorrhage by constricting the vessels. 
Alum should always be given alone, and it is to be 
remembered that it has a very injurious action on the 
teeth. 

Symptoms of Poisoning. 

In large doses alum produces gastro-enteritis, with 
frothing at the mouth. The treatment consists in pro- 
moting vomiting and washing out the stomach, giving 
magnesium hydrate in large quantities, or a weak 



30 MATERIA MEDICA FOR NURSES. 

solution of ammonium carbonate at intervals. Death 
has been caused in eight hours in an adult by J ii. 
of alum. 

Preparations of Alum. 

Alumini Sulphas. 
Aluminum Sulphate. 

Should be given diluted and with a glass tube. Dose, 
gr. x.-xx. (0.65-1.3 gm.) 

Alumen Exsiccatum, 
Dried Alum. 

Alum which has been deprived of its water by heat, 
and powdered. Combined with alcohol (in which it is 
insoluble), in the proportion of 3 L-iv. to alcohol f v.-vi., 
it is used to harden the skin, as a preventive of bed-sores. 

Ferrum (Iron). 

All the salts and preparations of iron are made directly 
or indirectly from the metal. 

Physiological Actions. 

Iron is the most important of the mineral tonics, and 
may be more properly described as a food rather than 
as a medicine, being one of the most essential constitu- 
ents of the red blood corpuscles. It exists normally in 
the blood in the proportion of 1 part iron to 230 parts 
red corpuscles, and in a state of health enough iron is 
taken with various kinds of food, to supply the demand. 
Beef especially, as an article of diet, provides iron, as it 
contains 1 part iron to 194 parts red corpuscles. 

Iron has been called the great respiratory food. In 
the lungs it takes up oxygen from the inspired air, and 
carries it to all the tissues. No function of the body 
can be carried on without oxygen ; the muscular system 
especially is dependent for its perfect activity on the 



THE METALS. 3 1 

presence of oxygen, and muscular power is in direct 
proportion to the efficiency of the respirations. 

The feeling of tone and energy, both bodily and 
mental, which belongs to perfect health, comes from an 
ample supply of oxygen, and it is in this primary way 
that iron acts as a tonic ; stimulates and strengthens 
the heart, nerves, and muscles; raises the tem- 
perature of the body and increases the appetite. 

It is not absorbed by the unbroken skin, but on ex- 
posed tissue and mucous surfaces its action is astringent, 
coagulating the albumin of tissue and plasma, diminish- 
ing the circulation by compression of the vessels, and 
arresting hemorrhage. Iron is thus classed as a Styptic 
or haemostatic. 

Taken internally there is an astringent taste, and the 
tongue and teeth are darkened by a sulphide which is 
deposited as a result of decomposition. If given in 
excess or on an empty stomach it decomposes the diges- 
tive fluid, and acts as an irritant and astringent upon 
the mucous membrane. 

The digestion or absorption of iron takes place partly 
in the stomach and partly in the intestines, and depends 
upon the presence, in normal quantities, of the gastric 
and intestinal juices. 

Iron has sometimes an irritant action on the bladder ; 
its astringency in the alimentary canal causes constipa- 
tion ; and it is said that it decreases the secretion of 
milk in nursing women. An excess of iron is eliminated 
from the system in almost every possible way, but prin- 
cipally by the faeces, which it colors black by forming a 
sulphide. 

The local irritant action of iron explains why it is 
always given well diluted and after meals. 

Incidental Effects. 

In administering a course of iron any one or more of 
the following symptoms may be noticed, indicating an 
excess in the system : Frontal headache, slight disturb- 
ances of the digestion, irritation of the stomach or of 
the bladder, a feeling of weight at the epigastrium, con* 



32 MATERIA MEDIC A FOR NURSES. 

stipaiion, a feverish condition. An acne of the face 
and chest is sometimes produced by iron, and the reduced 
iron causes eructations of gas. 

It is very important to remember that all preparations 
of iron stain clothing, carpets, — in fact every thing 
touched, and that the stains are with difficulty removed. 
Silver spoons should never be used for iron, but if they 
have been used, the stain will come off if rubbed with 
ammonia water undiluted. Oxalic acid will take the 
stains out of muslin or linen. 

Preparations of Iron. 

(Saline Combinations^) 

Tinctura Ferri Chloridi. 
Tincture of Ferric Chloride. 



Sometimes called the muriated tincture. 

It is reddish-yellow in color, and has peculiar proper- 
ties. It is the most frequently used of all the prepara- 
tions of iron. It is astringent, irritating', and some- 
what corrosive. It has diuretic and antispasmodic 
qualities, owing probably to the ether, and is antiseptic 
by virtue of the chlorine and iron ; tonic, as are all iron 
preparations. It contains about 4 $ of metallic iron. 

Tr. of iron should never be given at the same time 
with tea, or with other medicines containing tannin, as 
an ink-like combination results. It should not be added 
to whiskey, but may be well given in milk, being dropped 
in at the moment when it is to be taken. Iron attacks 
the teeth, unless properly diluted, and should always be 
given through a glass tube. When the throat is gargled 
with iron, the teeth should be brushed after each appli- 
cation, or washed off with salt water. 

Dose, TI[ ii.-xv. {y\ x. = gtt. xxv.), half an hour after 
meals, in a tumblerful of water. (0.1-1. gm.) 



THE METALS. 33 

Liquor Ferri et Ammoniae Acetatis. 
Solution of Acetate of Iron and Ammonia. 
Basham's Mixture. 

Composed of tr. of ferric chloride, dilute acetic acid, 
solution of ammonium acetate, elixir of orange, syrup, 
and water. It should be freshly made. 

Dose, § ss.-i., well diluted. 
(16.-32. gm.) 

Syrupus Ferri Iodidi. 
Syrup of Ferrous Iodide. 

Iodide of iron affects the teeth seriously. It has 
iodine, iron, and syrup, and exerts a special action on 
nutrition by means of the iodine. 

Dose, TTl v.-xl. (TT[ x. = gtt. xiii.), largely diluted. 
(0.3-2.6 gm.) 

Liquor Ferri Acetatis. 
Solution of Ferric Acetate. 

Contains about 7 $ of metallic iron. 
Dose, HI ii.-x. (fit x. = gtt. x.). 
(0.1-0.65 gm.) 

Mistura Ferri Composita. 
Compound Iron Mixture. 
Griffith's Mixture. 

Contains ferrous sulphate, potassium carbonate, and 
myrrh. 

Dose, § i.-ii. 

(32.-64. gm.) 

Liquor Ferri Subsulphatis. 

Monsel's Solution. 

Solution of Ferric Subsulphate. 

Contains about 13 </ of metallic iron. 

Ferrous sulphate, sulphuric and nitric acids are con- 
stituents of Monsel's solution. It has a deep red color 
and the consistency of syrup. It is an active Styptic, 



34 MATERIA MEDICA FOR NURSES. 

but it is rather uncertain in its action, sometimes causing 
severe sloughing, and is not much used. 

Pilulae Ferri Carbonatis. 
Pills of Ferrous Carbonate. 
Blaud's Pills. 

Contain sulphate of iron and carbonate of potassium, 
tragacanth, and glycerine. Dose, pil. i. 

Ferrum Reductum. 
Reduced Iron. 
Quevenne's Iron. 

A light gray powder, quite tasteless, and of all the 
preparations of iron the most free from astringency. 
Dose, 2-5 gr. (0.1-0.3 g m -)> taken after meals in pill 
form. It may be given to children in candy or lozenges. 

Pilulae Ferri Iodidi. 
Pills of Ferrous Iodide. 

Contain reduced iron, iodine, glycyrrhiza, acacia, and 
balsam of tolu. 

{Antidotes to Arsenic.) 

Ferri Oxidum Hydratum. 
Ferric Hydrate. 
Hydrated Oxide of Iron. 

As an antidote to arsenic this preparation of iron 
must be fresh, and may be quickly prepared by adding 
to several ounces of the tr. ferri chlor. enough ammonia 
water or sodium carbonate to form a precipitate, which 
will appear almost instantly. Continue adding the 
alkali until no more of the precipitate falls ; then turn it 
into a piece of muslin or a fine strainer and wash it well 
by letting cold water run freely through it, until all 
traces of the soda or ammonia are removed. Stir up a 
tablespoonful of the precipitate in milk or water, and 
give it, repeating as often as necessary. It is harmless ; 



THE METALS. 35 

and about 8 grains of it are required to neutralize i grain 
of the poison. 

Ferri Oxidum Hydratum cum Magnesia. 
Ferric Hydrate with Magnesia. 

Made by combining the solution of the ferric sulphate 
with magnesia. It is said to be the best antidote for 
arsenic. 

Dialyzed Iron. 

An antidote to arsenic ; also given medicinally. It is 
said that it does not blacken the teeth nor constipate. 
Dose, from 20 to 40 drops. It should always be given 
alone. 

Manganesium (Manganese). 



Manganese is found native in the form of the black 
oxide. 



Physiological Actions. 

Manganese is found in the human body associated 
with iron. They are found together in the blood, hair, 
and bile, the proportion in the blood being 1 part of 
manganese to 20 of iron. The preparations of manga- 
nese are gastro-intestinal irritants. In small doses they 
aid digestion and promote appetite. They enter 
the blood probably as albuminates. Used in excess 
they lower the heart action, diminish the pulse rate, and 
cause loss of muscular power and paralysis. 

The action of manganese on the tissues, blood, and 
excretory organs is not clearly defined. It is supposed 
that the salts are decomposed before being absorbed, ex- 
cept when in poisonous doses. 



36 MATERIA MEDIC A EOR NURSES. 

Preparations of Manganese. 

Potassii Permanganas. 
Potassium Permanganate. 

Made from the black oxide of manganese, potassium 
chlorate, and a solution of caustic potash, by a very 
elaborate chemical process. It has the form of dark- 
purple slender prisms, inodorous, with an astringent 
sweet taste ; soluble in 16 parts of water. It should be 
kept in the dark. 

Potassium permanganate in the pure state is irritant 
and caustic. In solution it is stimulating and heal- 
ing. In the latter form it gives out oxygen in the form 
of ozone, and changes into hydrated peroxide of man- 
ganese, losing its purple color and becoming brown. 
This change does not occur with the crystals. 

This oxidizing power gives it special attributes as an 
antiseptic, disinfectant, and deodorant, but practi- 
cally it is not useful in disinfecting excreta, as the 
amount required to be effectual would make it enor- 
mously expensive. 

It is oftenest and most satisfactorily used as a deodor- 
izer, in the one-per-cent solution, as a wash, douche, 
spray, or gargle, for foul, carious, or gangrenous dis- 
charges. It is also used in skin disinfection, in a super- 
saturated solution. 

The stains made upon linen by this salt may be 
removed with oxalic acid (lemon juiced, or water with 
muriatic acid. 

Given internally, the dose, gr. ss.-ii., is freely diluted 
with distilled water ; or, if given in pellets, boiled or 
filtered water should be given with it to dilute it after 
being swallowed. It should be given on an empty 
stomach. 

Mangani Sulphas. 
Manganese Sulphate. 

In full doses an emetic and cathartic, with action 
on the liver, a<? is shown by the bile discharged after 
purgative doses. Dose, gr. ii-v. (0.1-0.3 gm.) 



THE METALS. 37 

Hydrargyrum (Mercury). 
Quicksilver. 

Mercury is obtained from cinnabar by roasting and 
distilling with lime. It is a silver-white metal, liquid, 
and giving off vapor at ordinary temperatures, and capa- 
ble of being entirely volatilized by heat. All the different 
preparations are derived directly or indirectly from the 
metal itself. 

Physiological Actions. 

In the metallic form mercury is inert, large amounts 
of the pure metal having been swallowed and discharged 
from the intestines without poisoning or injury ; but in 
the form of vapor, or any of its preparations, it is very 
readily absorbed by the pulmonary and other mucous 
membranes, by the alimentary canal, and by the skin 
and tissues, either whole or broken. The constitutional 
effects may be reached in any one or all of these ways. 

All mercurials are antiseptic and disinfectant. 

The local action of mercury in moderate strength, 
either externally or internally, is astringent, antiphlo- 
gistic, and Stimulant. In large or concentrated doses 
it is irritant to the stomach and intestines, and in some 
forms is a locally acting purgative. 

In various pathological conditions of the system 
mercury exerts an influence as an alterative, through 
some power over nutrition which is not perfectly under- 
stood. It is considered a specific in some forms of 
syphilis. 

Mercury is excreted by the saliva, perspiration, milk, 
urine, and bile. 

Symptoms of Poisoning. 

The mildest evidences of ov^r-doses of mercury are : 
slight fetor of the breath and soreness if the teeth are 



38 MATERIA MED1CA FOR NURSES. 

knocked together or struck ; a metallic taste next ap- 
pears. After this comes salivation, an abnormal amount 
of fluid being poured out from the salivary glands, and 
small ulcers appear on the lips, gums, and tongue. A 
feeling of constriction of the throat, which is found 
among the symptoms of acute poisoning, has been caused 
in some susceptible persons by a single medicinal dose of 
mercury. 

When its use is continued beyond this point salivation 
increases. The gums become swollen and spongy, and 
bleed easily. The tongue swells, sometimes protruding 
from the mouth. The teeth are loosened, and a dark 
line is seen at their upper margin. In some cases ulcera- 
tion of the soft parts and necrosis of the jaw-bones result, 
In pronounced chronic poisoning, in addition to these 
symptoms, there are abdominal pains, nausea, vomiting, 
and diarrhoea, anaemia, emaciation and general weak- 
ness ; aching pains in the bones and joints ; loss of 
hair ; a trembling or shaking palsy ; and paralysis, with 
a brown tint of the skin. In some cases there is wrist- 
drop. Chronic poisoning may be caused indirectly by 
exposure to the metal or its fumes, as in various occupa- 
tions, and it may come on very suddenly. 

Acute poisoning will be described under corrosive 
sublimate. 

Preparations of Mercury. 

Hydrargyri Chloridum Corrosivum. 

Corrosive Sublimate ; Corrosive Mercuric Chloride. 

Known as bichloride of mercury, or " bichloride." 
Made by subliming bisulphate of mercury with chloride 
of sodium. Soluble in 1 6 parts of cold water. It is a 
powerful germicide under certain conditions, and is ordi- 
narily used as a disinfectant solution for the skin, for 
dressings, etc., in a strength of i-iooo. It is not an effi- 
cient disinfectant in the case of stools, or bloody or 
purulent discharges, as it hardens albumin, thus forming 
a protective shell within which germs retain perfectly 
their vitality. 



THE METALS. 39 

White materials are stained yellow by bichloride of 
mercury, and it is not always desirable therefore as a 
disinfectant for clothing. 1 

The external use of bichloride of mercury, as in 
dressing surgical and obstetrical cases, may produce 
symptoms of poisoning which must not be overlooked. 
Among the latter class of cases an eruption of small 
pimples appears about the buttocks and may extend 
down the limbs. Sore gums, fetid breath, and salivation 
may follow. The eruption should always be reported as 
soon as noticed. In chronic poisoning by this prepara- 
tion there is more tendency to abdominal pains, diarrhoea, 
and colic. 

Internally in small over-doses it causes nausea, burning 
in the stomach, colicky abdominal pain, and diarrhoea ; 
or, these symptoms may not be prominent and a sore 
ulcerated mouth may show the toxic action. In poison- 
ous doses it is a violent irritant and caustic, and the 
symptoms appear in a few moments — viz., a metallic 
taste, the mucous lining of the mouth sometimes glazed 
and white, vomiting of mucus and blood, dysenteric 
purging, tenesmus, and cramps, with fetid breath. Vio- 
lent abdominal pain is sometimes, not always, present. 
The urine is diminished, may contain blood and albu- 
min, may be suppressed. In the course of two or three 
hours there is collapse, with small, quick, irregular pulse, 
pinched, anxious face, cold extremities, syncope, convul- 
sions, coma, and death. 

The smallest fatal dose is not absolutely certain, but 
may be put at 3 to 5 grains. Death usually takes place 
in from 1 to 5 days, but may be earlier or later than 
this. On recovery the convalescence is long and tedious. 

The antidote is albumin, milk, gluten (flour), or, best 
of all, the white of egg, in proportion of 1 egg to 4 grains 
of the poison. More than this is said to redissolve the 
mercury. 

Vomiting should be promptly induced and actively kept 
up for a time after taking the antidote. 

1 For this purpose the solution of salt and sulphate of zinc is better- 
See zinc. 



40 MATERIA MEDICA FOR NURSES. 

Dose, gr. 5*5— jfo, we ^ diluted and given after meals. 
All other non-purgative preparations are, as a rule, taken 
after meals also. (0.0013-0.003 gm.) 

Hydrargyri Oxidum Flavum. 
Yellow Mercuric Oxide. 

Dose, gr. t^-tV (0.0013-0.006 gm.) 
Hydrargyri Iodidum Viride. 
Green Iodide of Mercury. 
Protiodide of Mercury. 

Dose, gr. ^-\. (0.006-0.03 g m -) 
Hydrargyri Iodidum Rubrum. 
Red Iodide of Mercury. 
Biniodide of Mercury. 

Dose, gr. ^ -tV- (0.002-0.006 gm.) 
Hydrargyri Cyanidum. 
Mercuric Cyanide. 

Dose, gr. t1o - to- (0.0006-0.006 gm.) 
Hydrargyri Chloridum Mite. 
Mild Mercurous Chloride. 
Calomel. 

Made by subliming sulphate of mercury and chloride 
of sodium. A white, insoluble powder, used as a 
cathartic and indirect cholagogue. 

It increases the amount of bile evacuated from the in- 
testines without directly increasing the amount secreted 
by the liver. In the ordinary routine of digestion part 
of the bile in the intestines is re-absorbed and carried 
back to the liver ; but by the action of calomel this is all 
expelled from the body, the result being that the next 
quantity secreted must all be newly formed, out of fresh 
materials. 

Salivation occurs more frequently from the use of 
calomel than from other mercurials except blue pill, and 
it has an insidious harmful effect on the teeth, tending to 
retract the gums and expose the unprotected roots. Be- 
ing tasteless and insoluble, it is best given dry on the 
tongue, with some water after it. It is slow in its action, 



THE METALS. 4 1 

requiring from 8 to 12 hours if given alone. Salty food 
should not be taken after calomel, as alkaline chlorides 
change it into bichloride. Acids also are often forbid- 
den, though this is not now considered very important. 

Children bear relatively larger doses of calomel than do 
adults. Dose, gr. y^-gr. x. (0.006-0.65 g m -) 

Massa Hydrargyri. 
Blue Mass. 

Made by combining mercury in the metallic state with 
glycyrrhiza, althaea, etc. It contains one third its weight 
of the metal, and is used, like calomel, as a purgative, 
but is milder. Each pill contains usually from 3 to 5 
grains of the mass, equalling gr. \ of metal. Dose, gr. 
i.-x. (0.06-0.65 g m -) 

Hydrargyrum cum Creta. 
Mercury with Chalk. 

A gray powder, similar in its properties and strength, 
to blue mass. It may be placed dry on the tongue 
or mixed with glycerine. Dose, gr. i-x. The mercurial 
purgatives are abused by numbers of persons who 
prescribe for themselves. They should never be taken 
without authority, and it is also to be remembered that 
many quack purgative medicines, " liver pills," etc., con- 
tain mercury in uncertain quantities, and are harmful. 

Unguentum Hydrargyri. 
Mercurial Ointment. 
Blue Ointment. 

Composed of mercury, lard, suet, and oleate of mercury. 
Unguentum Hydrargyri Oxidi Flavi. 
Ointment of Yellow Oxide of Mercury. 

Strength, 10 </ . 
Unguentum Hydrargyri Oxidi Rubri. 
Ointment of Red Oxide of Mercury. 

Strength. 10 f . 
Unguentum Hydrargyri Nitratis. 
Ointment of Nitrate of Mercury. 
Citrine Ointment. 



42 MATERIA MEDIC A EOR NURSES. 

Strength, 7 $. Contains also nitric acid. 
Black Wash. 

Calomel 3 i, lime-water Oj. Used externally. 
Yellow Wash. 

Corrosive sublimate 3 ss, lime-water Oj. Used ex- 
ternally. 

These two washes depend for their efficacy on the 
black and yellow oxides which are formed by the union 
with lime-water. They are used for syphilitic ulcers. 
The yellow wash is the most stimulating. 

Mercury, besides being given internally, is used in the 
form of vapor baths and inunctions. There are many 
preparations, and with all of them constitutional symp- 
toms are likely to appear, and must always be watched for. 

It is of great importance that the diet of persons 
taking mercury should be ample and nutritious. 

Mercurial ointment should be rubbed in with a piece 
of flannel ; nurses have been salivated by using their 
hands for this purpose. 

Arsenium (Arsenic). 

Metallic arsenic is inert, and is not used in medicine. 

Acidum Arsenosum. 
Arsenous Acid. 
White Arsenic. 

Obtained principally as a secondary product in the 
roasting of cobalt ores. It is not a true acid, but an 
anhydride, or acid deprived of its water. All the 
preparations of arsenic are derived from white arsenic. 

Physiological Actions. 

Arsenic in concentrated form applied to the tissues 
causes inflammation, followed by ulceration and slough- 
ing. It has therefore been used as an escharotic, but 



THE METALS. 43 

its action is very painful and is attended with danger, 
as arsenic is readily absorbed from broken skin, ulcers, 
and mucous membrane, unless there is enough inflamma- 
tion to throw it off ; it being understood that when 
an inflammatory process is going on, the absorptive 
capacity of that part is checked. 

In the stomach in medicinal doses arsenic does not 
combine with the albuminous contents of the organ, but 
remains unchanged and acts directly on the mucous 
membrane, stimulating the nerves and vessels, causing a 
sense ot heat and hunger, and promoting the gastric 
functions. 

Arsenic enters all organs and tissues, increases tissue 
changes and the vital activity of the whole system. It 
does not combine with the tissues, and is excreted 
chiefly by the urine, and also by the skin, liver, and 
intestines. Arsenic is therefore, in medicinal doses, a 
stomachic and general tonic, increasing the appetite 
and improving digestion and general nutrition. 

It stimulates the secretions, peristaltic action, the brain, 
heart, and respiratory centre. 

Symptoms of Poisoning. 

In giving arsenic, the first signs which indicate over- 
dosing are : a slight puffiness about the eyelids, without 
redness, and noticeable first in the early morning, dis- 
appearing later ; an itching of the eyelids ; tingling or 
itching of the fingers, abdominal pain or soreness. 
Increasing symptoms of over-dosing are : a metallic 
taste, nausea, vomiting, diarrhoea, and sometimes dysen- 
teric stools, with tenesmus ; an irritable and feeble heart 
action ; palpitations and oppressed breathing ; eczema 
and other skin eruptions ; trembling and stiffness of the 
joints ; and albuminuria. 

In acute poisoning the symptoms are of two varieties, 
gastro-intestinal and cerebral. The former is much more 
common, and is marked by a burning pain at the epigas- 
trium, radiating over the abdomen ; violent and uncon- 
trollable vomiting of matter, first mucous, then bilious, 
and finally serous ; intense thirst and dryness of the 



44 MATERIA MEDICA FOR NURSES, 

mouth and throat ; stools bloody and offensive, some* 
times involuntary ; strangury ; sometimes bloody urine, 
or suppression ; great restlessness and agitation ; dysp- 
noea ; a rapid, weak, intermittent pulse ; cold breath ; 
shrunken face ; cold and clammy skin, and final col- 
lapse, consciousness being retained until death occurs. 
In the cerebral form there is sudden and deep insensi- 
bility, ending in death, without intestinal symptoms. 
Occasionally there is a combination of both sets of 
symptoms ; also they may vary according to the form 
and dose in which the poison has been taken. The time 
in which they come on is usually from half an hour to an 
hour after taking the poison, and death has occurred in 
a few hours, but the average length of time is about 
twenty-five. It often happens that recovery is made 
from the first effects, with death from exhaustion or 
secondary causes many days, or even weeks, after. 

The fatal dose for an adult may be put at from 2 to 4 
grains. 

Treatment of Poisoning. 

In treating poisoning by arsenic, if vomiting has not 
already been caused by the poison, emetics should be 
given : a tablespoonful of mustard in a glass of warm 
water, followed by large quantities of mucilaginous and 
albuminous drinks, such as flaxseed tea, milk, with white 
of egg, etc. The antidotes, hydrated sesquioxide of 
iron and hydrated magnesia, have been described under 
iron and may be given in water, a tablespoonful at a 
time, every few minutes while necessary. Castor-oil 
should be given to clear the bowels. If the poison has 
been taken in solution the antidotes will precipitate it in 
an insoluble form, but no confidence can be placed in 
them if the powder has been taken, as rat-poison (often 
used in suicidal cases). The early and complete re- 
moval of the poison by emetics and purgatives is then 
the only real hope. The urine must be watched, as 
suppression may occur, and, while the patient lives, q 
daily specimen saved for examination. 



THE METALS. 45 

Arsenic is not accumulative, and is an irritant, not a 
corrosive poison. After death the stomach and in- 
testines are found to be deeply reddened and inflamed, 
but not ulcerated. The post-mortem appearances, as 
well as many of the symptoms, resemble those of cholera 
very strongly. Chronic poisoning is caused by the in- 
halation of arsenical fumes, by the use of wall-papers 
and clothing dyed with materials containing arsenic, and 
by eating adulterated candy and other articles of food. 

Preparations of Arsenic. 

Acidum Arsenosum. 
Arsenous Acid. 

Dose, gr. -^o- T V> we ll diluted and given after meals. 
(0.0013-0.006 gm.) 
Liquor Acidi Arsenosi. 
Solution of Arsenous Acid. 

Contains arsenous acid 1 part in 100, and hydrochloric 
acid 1 part in 200. 

Dose, TT[ ii.-x. (v\ x. = gtt. x.), well diluted and given 
after meals. (0.1-0.65 g m -) 
Liquor Potassii Arsenitis. 
Solution of Potassium Arsenite. 
Fowler's Solution of Arsenic. 

Contain tr. of lavender and arsenous acid and bi- 
carbonate of potassium, 1 part of each in 100. Five 
minims represent gr. £±. 

Dose, TTl ii.-x. (tt[ x. = gtt. x.), well diluted and given 
soon after meals. (0.1-0.65 g m 
Arseni lodidum. 
Iodide of Arsenic. 

Dose, gr. io~\. 
Liquor Arseni et Hydrargyri Iodidi. 
Solution of Arsenic and Mercuric Iodide. 
Donovan's Solution. 

A very powerful alterative, containing 1 <f> each of 



46 MATERIA MEDICA FOR NURSES. 

iodide of arsenic and red iodide of mercury. It is cap- 
able of acting as a corrosive poison, and may salivate. 
Locally it is a violent irritant. 

Dose, 3-10 mm., well diluted. (0.008-0.65 gm.) 

Cupri Arsenis. 
Paris Green. 

Is not used medicinally, but is often taken as a means 
of suicide. 

It may be repeated in conclusion that all preparations 
of arsenic should be given well diluted, and soon after 
meals, to avoid the local irritant action on the stomach ; 
and that it is necessary to keep close watch for the con- 
stitutional symptoms, which may at first be so unobtru- 
sive as to escape notice. 

Antimonium (Antimony). 

The metal itself (stibium) is not official, all prepara- 
tions being derived from black antimony, which is ob- 
tained from siliceous matter, purified and powdered. 

Antimonii et Potassii Tartras. 
Antimony and Potassium Tartrate. 
Tartar Emetic. 

Made by boiling cream of tartar and water with oxide 
of antimony. 

Tartar emetic, applied to the skin, is a strong counter^ 
irritant, and excites an eruption closely resembling that 
of smallpox, viz., small papules, becoming vesicular and 
finally pustular. It is now but little used in this way. 
Internally it is irritant, and, as an emetic, its action is 
partly direct— that is, acting immediately on the walls of 
the stomach, and partly indirect, or acting on the nerve- 
centre in the medulla which controls vomiting. Tartar 
emetic causes nausea and depression both before and 
after the act of vomiting, and is therefore not well 
suited to cases where rapid action with as little depres- 
sion as possible is required, as in poisoning. 



THE METALS. 47 

In small continued doses the local action of tartar 
emetic is apt to produce loss of appetite, nausea, diar- 
rhoea, and pain. In the tissues antimony has an alter- 
ative action, the special results being an increase of the 
waste products of the body, with a lessening of oxygena- 
tion, and fatty degeneration of the organs. 

Tartar emetic depresses the circulation even in small 
doses, the first effect visible after a therapeutic dose being 
a diminution of the pulse and increase of perspiration. 

With a continuance of the medicine the pulse becomes 
weakened, soft, and compressible, infrequent and irreg- 
ular, and fainting may occur. Respiration is weakened, 
inspiration being shortened, and expiration lengthened. 

The nervous system is depressed, a feeling of languor, 
sleepiness, and lassitude being produced by a moderate 
dose. It affects the muscular system so powerfully that 
before chloroform came into use tartar emetic was em- 
ployed to produce muscular relaxation in the reduction of 
dislocations, etc., and the depressed state so brought about 
lasted for six or eight days in spite of heart stimulants. 

Emetic doses cause great muscular weakness, tremors, 
and aching of the muscles, loss of power to stand, with 
free perspiration and an increase of saliva. 

Antimony is excreted by all the mucous surfaces, the 
liver, kidneys, and skin. 

Its excretion by the bile shows it to be a hepatic 
Stimulant ; in passing through the kidneys it acts as a 
diuretic, and through the skin as a diaphoretic. 

The characteristic pustular eruption is sometimes 
caused by its internal use. 

Symptoms of Poisoning. 

The symptoms of poisoning are very like those of the 
collapse of cholera, viz. : shrunken features, cold surface 
and breath ; great epigastric pain, vomiting, and purging ; 
small, rapid, soft, and irregular pulse ; cyanosis ; syn- 
cope ; cramps of the lower extremities ; insensibility to 
stimulants ; intense prostration ; delirium ; tetanic spasms 
in some cases, or aphonia. 

The quantity of tartar emetic which will destroy life is 



48 MATERIA MED1CA FOR NURSES. 

not definitely known. The smallest fatal dose recorded 
is f of a grain in the case of a child ; gr. ii. has caused 
death in an adult, while doses have been recovered 
from, ranging from gr. xx. to § i. It is probable that, 
under ordinary circumstances favoring the action of the 
poison, gr. x. or xv. would destroy life, if taken at once, 
or a smaller quantity, if divided. The symptoms come 
on rapidly, and death may occur in a few hours, or days, 
or may be delayed for several weeks. 

Treatment of Poisoning. 

The antidote is tannic acid ; or substances containing 
it, as strong tea. Opium, and alcoholic stimulants, with 
demulcent drinks, are given. 

Dose of tartar emetic, gr. yg-i., diluted. (0.005- 
0.06 gm.) 

Vinum Antimonii. 
Wine of Antimony. 

Contains of tartar emetic gr. ii. to § i. 
This preparation decomposes on being kept, and a 
fungoid growth takes place in it which unfits it for use. 
Dose, TT[ v. (fT[ x. = gtt. xii.)-3 ss. (0.3-2. gm.) 

Pilulae Antimonii Compositae. 
Compound Pills of Antimony. 
Plummer's Pills. 

Contain sulphurated antimony, mild mercuric chloride, 
guiac, and castor oil. 

Syrupus Scillae Compositus. 
Compound Syrup of Squill. 

Contains squill, senega, phosphate of lime, and dilute 
alcohol, with tartar emetic, about gr. f to § i. Syrup of 
squill is sometimes used as a domestic remedy for chil- 
dren, without a physician's order, and as tartar emetic is 
not a safe medicine for children, its unauthorized use has 
sometimes had fatal effects, and should always be strongly 
discouraged. 

Bismuthum (Bismuth). 

A crystalline metal, impure in its crude state, and con- 
taining arsenic as one of the impurities. It goes through 
various chemical processes by way of purification. 



NON-METALLIC ELEMENTS. 49 

Physiological Actions. 

Externally and internally bismuth acts as a mild seda- 
tive and astringent. It is useful as a dry application 
in the first stages of bed-sores, as a dressing for burns and 
blisters, and may be satisfactorily used on small fresh 
wounds. It is given internally as an astringent, and in 
large quantities colors the faeces black or dark-gray. 

Bismuthi Subnitras. 
Subnitrate of Bismuth. 

A heavy white powder, odorless and almost tasteless, 
insoluble in water. The easiest way to give it is mixed 
in a little glycerine and diluted with milk or water ; or 
it may be given in wine, or placed dry on the tongue. 

Dose, gr. v.- 3 i. (0.3-4. gm.) 



NON-METALLIC ELEMENTS. 

Phosphorus (Phosphorus). 

A non-metallic element made from bones, by treating 
bone-ash with sulphuric acid and water. It is a semi- 
transparent, almost colorless, wax-like solid, with a 
peculiar garlic odor : it is luminous in the dark, is in- 
soluble in water, and soluble in ether and in oils. 

Phosphorus is a constituent of the most important 
tissues of the body, especially of the nervous system, 
where it exists as phosphorized fats. In the bones it is 
present as phosphate of calcium, magnesium, and sodium. 
It is contained in various articles of food, especially 
in fish and vegetables. 

Physiological Actions. 

In small doses phosphorus acts as a tonic and alter- 
ative, and stimulates the nutritive processes, especially in 
the case of the nervous and bony tissues. Given for a 
considerable length of time in small doses it affects the 
structure of bone, and makes the spongy portion firm and 
compact. The heart is stimulated by medicinal doses of 
phosphorus, and the temperature slightly raised. 
4 



50 MATERIA MEDIC A FOR NURSES. 

Full doses given for a long time disturb the stomach, 
producing eructations of gas (phosphide of hydrogen), 
and depress the heart. Perspiration and urine are in- 
creased by phosphorus, and the latter becomes reddish 
and has the odor of violets. 

Symptoms of Poisoning. 

Phosphorus is an irritant poison, and the symptoms 
vary somewhat according to the state in which it is taken, 
appearing more quickly after taking a solution in oil, or 
the paste used as a vermin killer, than after match heads 
or ordinary phosphorus have been used. In the latter 
case the symptoms do not come on at once ; some hours 
usually — sometimes one or two days — intervening before 
they show themselves. Then epigastric pain and burning 
begin, with a burning sensation in the throat, a taste of 
garlic in the mouth, and an odor of garlic to the breath ; 
great thirst, nausea, and vomiting. During the first 
eight or ten hours the vomited matters have a garlic odor 
and are luminous in the dark, and if purging occurs, the 
faecal matters are sometimes luminous, as is also the urine. 
Vomiting sometimes continues through the whole of the 
attack, but usually stops about the second or third day. 
Jaundice is a characteristic but not an invariable symp- 
tom. It appears from the third to the fifth day, and with 
it vomiting may reappear, exuded blood giving a 
peculiar appearance which is described as "coffee- 
ground." There is great prostration, with a small, 
frequent, almost imperceptible pulse, and cold skin. The 
mind may remain clear, or there may be noisy delirium,, 
Sometimes convulsions occur, or paralysis. Death may 
take place suddenly from collapse and paralysis of the 
heart, but more commonly the patient dies comatose 
from gradual failure of respiration and circulation. The 
time at which death occurs varies from a few hours to 
several weeks, the average time being several days or a 
week. 

The fatal dose is stated to be between gr. f and ii., 
though it may vary according to circumstances, and 
large quantities have been recovered from. 



NON-ME TALLIC ELEMENTS. 5 [ 

Treatment of Poisoning. 

The chemical antidote is the crude French acid 
turpentine, which is given in doses of 3 ss. every fifteen 
minutes. After the poison has entered the blood there 
is no known antidote, and therefore, emetics and pur- 
gatives are of the greatest importance. Sulphate of cop- 
per is the emetic used, and forms an insoluble compound, 
phosphide of copper. It is given in dilute solution, gr. 
ii. at a time, every five minutes until vomiting is caused? 
and after that in small doses, gr. J, every twenty minutes 
as long as ordered. Hydrated magnesia may be used as 
a purgative. Mucilaginous and albuminous drinks are 
given, and all oils and fats carefully avoided, both in 
medicine and nourishment, as they dissolve phosphorus 
and hasten its absorption. 

Chronic phosphorus poisoning is found among art- 
isans who are exposed to the fumes, and is especially 
characterized by necrosis of the jaw. This form of 
poisoning is not as common now, since improved 
ways of making matches have been introduced, as it 
once was. 



Preparations of Phosphorus. 

Oleum Phosphoratum. 
Phosphorated Oil. 

Contains stronger ether, oil of almond, with phospho- 
rus in a strength of 1 in 100. One minim equals gr. y^ 
of phosphorus. 

Dose, TU i.-iii. (TT[ x. = gtt. xv.). (0.06-0.02 gm.) 

Pilulae Phosphori. 
Pills of Phosphorus. 

Each contains gr. y-J-g- of phosphorus. (0.0006 gm.) 



52 MATERIA MEDIC A FOR NURSES, 

Calcii \ 

Fern \ Hypophosphis. 
Potassii I 

Sodii ) 

Dose, gr. x.- 3 ss. (0.65-2. gm.) 

Syrupus Hypophosphitum. 
Syrup of Hypophosphites. 

Contains hypophosphite of lime, about gr. iii. to 3 i. y 
and of soda and potash each about gr. i. to 3 i-, with 
citric acid, spirits of lemon, and sugar. 

Dose, 3 i.- 3 ii., diluted. (4.-8. gm.) 

Chlorum (Chlorine). 

Chlorine is a greenish-yellow gas, belonging to the 
halogen group of elements. The title " halogen " is 
derived from the Greek word meaning sea, and is so 
given because the most important members of the group 
are obtained directly or indirectly from the ocean — viz. : 
chlorine, obtained from sea-salt ; bromine, from sea- 
water ; and iodine, from sea-weed. 

Chlorine itself is not official, but is represented in 
medicine by several of its compounds ; also by hydro- 
chloric acid and chlorinated lime, by which it is fur- 
nished. Chlorine is irrespirable, and of strong penetrating 
odor. It is soluble in water, in the proportion of two 
parts gas to one part water. If inhaled in any quantity 
it irritates the lining of the air-passages, causes spasm of 
the glottis, and narcotizes the brain. 

It is a most powerful disinfectant, antiseptic, and 
deodorant, its great activity in these respects being due 
to its affinity for hydrogen, by which it decomposes com- 
pounds containing hydrogen, and sets oxygen free in its 
most active state, as ozone. It is not used in disinfect- 
ing clothing, as it destroys the color and texture of 
fabrics, nor the person, as it cannot be breathed in a 
strength sufficient to destroy germs. For disinfecting 
rooms it may be prepared as follows : Mix equal parts 



NON-METALLIC ELEMENTS. 53 

of common salt and black oxide of manganese. To a 
tablespoonful of this powder, in a saucer, add a table- 
spoonful ( 1 ss.) of strong sulphuric acid diluted one 
third with water. In cold weather the saucer should be 
heated. This will produce enough chlorine to disinfect 
a room thirty-two feet square. 

Calx Chlorata. 
Chlorinated Lime. 

Made by the action of chlorine on slaked lime, con- 
taining 35 per cent, chlorine. Its action as a disinfect- 
ant is that of chlorine, and when so used it should be 
perfectly fresh or it is valueless. To test it, dissolve a 
little in water ; if the solution is clear, it is good, but if 
it has lost its chlorine the solution will be turbid and 
milky. This preparation is sometimes improperly called 
chloride of lime. 

Liquor Sodae Chloratae. 
Solution of Chlorinated Soda. 
Labarraque's Solution. 

Contains sodium carbonate and chlorinated lime. A 
greenish-yellow liquid, with sharp salty taste and very 
slight odor of chlorine. It is a good preparation for 
cleansing purposes in sick-rooms, wards, etc., in weak 
solution. In full strength it removes stains from glass. 
Medicine droppers, douche nozzles, and other small 
articles which are hard to clean may be soaked in it 
until the stains come away. It is sometimes given 
internally, in half a tumblerful of sweetened milk or 
water. 

The antidote, in case of poisoning by any of the 
chlorine compounds, is albumin ; white of egg, milk, 
and flour. Dose, 3 ss.— ii. (2.-8. gm.) 

Bromum (Bromine). 

A liquid element obtained from sea-water and from 
certain mineral springs. A dark, brownish-red, very 



54 MATERIA MEDIC A FOR NURSES. 

volatile liquid, of strong and suffocating odor. When 
brought into contact with organic matter it oxidizes and 
destroys it with great rapidity. Its local action is, there* 
fore, powerfully irritant and escharotic. It is also a 
deodorant and antiseptic. It is never given inter- 
nally, alone, but has been used as a caustic, and the 
vapor has been used medicinally. 

Preparations of Bromine. 

Potassii Bromidum. 
Potassium Bromide. 

Prepared by adding a solution of pure carbonate of 
potash to a solution of bromide of iron, filtering, and 
evaporating. Colorless crystals, soluble in i T 6 -g- parts 
water. 

Physiological Actions. 

Potassium bromide lessens cerebral activity, and the 
tendency to " emotionalism " ; diminishes the sensibility 
and irritability of the mind in various nervous states ; 
such, for instance, as result from excessive mental strain, 
anxiety, or intellectual work ; and produces a condition 
of ansemia of the brain such as is found in natural sleep. 
It is thus an indirect hypnotic, not acting like opium, 
or chloral, but inducing sleep by bringing about a physio- 
logical condition favorable to its advent. Bromide of 
potash is depressing to the heart and respirations, both 
being slowed and weakened by its action. The spinal 
centres, spinal nerves, and the muscles are all depressed, 
and the temperature somewhat lowered, though not to 
any marked extent. Bromide of potassium contains 66 
per cent, of bromine. 

Dose, gr. x.-lx. (0.65-2.6 gm.) 

Ammonii Bromidum. 
Ammonium Bromide. 

Prepared by precipitating the freshly made solution of 
bromide of iron with ammonia water. The salt remain- 



NON-METALLIC ELEMENTS. 55 

ing in solution is crystallized and powdered. It is soluble 
in i \ parts of water. The effects and uses of bromide 
of ammonia are very like those of the bromide of potash, 
and it is said to be, in addition, slightly stimulating. 
It is not much used. 

Dose, gr. x.-lx. (0.65-2.6 gm.) 

Sodii Bromidum. 
Sodium Bromide. 

Colorless crystals, soluble in iy 2 ^ parts of water, and 
containing 78 per cent, of bromine. It resembles potas- 
sium bromide, and has very much the same qualities. 
It is considered less depressing, and the least toxic of 
all the bromide preparations. There is a variety of 
opinions as to its hypnotic power compared with that of 
potassium bromide. 

Dose, 3 ss.-ii. (2.-8. gm.) 

Lithii Bromidum. 
Lithium Bromide. 

A granular, very soluble salt, containing 92 per cent, 
of bromine. In addition to the hypnotic power of the 
bromides in general it is said to have some tonic and 
diuretic action. 

Dose, gr. v.-xx. (0.3-1.3 gm.) 

Incidental Effects, 

In giving a course of the bromides it is very essential 
that the state of the digestion and of the bowels be care- 
fully watched, and the latter strictly regulated, for the 
accumulation of an excess of bromine in the system 
causes a series of symptoms known as " bromism." The 
first is usually a salty taste in the mouth, with salivation 
and fetid breath. Next come drowsiness, heaviness, and 
sluggishness of intellect, loss of memory, partial aphasia, 
depressed spirits, a staggering gait, dull, listless expres- 
sion, sluggish pupils, and sometimes an infrequency of 
winking. 



56 MATERIA ME DIC A FOR NURSES. 

One of the marked features of bromism is the appear- 
ance of eruptions of the skin, in great variety, and of 
varying severity. All manner of skin lesions have been 
described, as resulting from the use of bromine, even to 
one resembling that of smallpox. The most common is 
a simple acne or eruption of pimples. It sometimes 
occurs early, or after the use of small doses, yet is not 
always among the first symptoms. 

The bromides are excreted by the kidneys chiefly, 
^Iso by the salivary and mammary glands, the skin, and 
all mucous surfaces. They are rapidly diffused, appear- 
ing in the secretions a few moments after being taken. 

Iodum (Iodine). 

Iodine is a non-metallic element of bluish color, de- 
rived chiefly from the ashes of sea-weeds ; not readily 
soluble in water ; soluble in ether, alcohol, and glycerine. 
It is never given internally in crude form. 

Physiological Actions. 

Applied externally iodine is an irritant and vesicant, 
and stains the skin yellow, or, in repeated applications, 
deep brown. It causes some pain, with a feeling of 
warmth, and desquamation may follow its use. It is 
absorbed into the blood partly through the skin and 
partly in the form of vapor. 

The vapor of iodine, like that of chlorine but in a 
feebler degree, decomposes sulphuretted and phosphu- 
retted compounds, and is, therefore, antiseptic and 
disinfectant. Internally iodine excites a sensation of 
heat and burning in the stomach. In sufficient quantity 
it is an irritant poison, causing inflammation of the lining 
of the stomach, severe pain in the abdomen, vomiting, 
and purging. The matters vomited have a yellow color, 
except when farinaceous food has been taken ; in this 
case they are blue or purplish. The amount of iodine 
necessary to produce toxic symptoms varies with consti- 
tutional peculiarities and with the kind and amount of 
food in the stomach. Death has been caused in twenty* 



NON-METALLIC ELEMENTS. 5? 

four hours by 3 i. The antidote is starch or flour stirred 
up in water, and emetics should be given afterwards. 

Iodine is rapidly excreted, appearing in the urine, the 
perspiration, saliva, bile, milk, and mucous secretions, 
especially of the air-passages. 

Preparations of Iodine. 

Potassii Iodidum. 
Potassium Iodide. 

Made by dissolving iodine in liquor potassse, evapora- 
ting, and treating the residue with wood charcoal. 

Potassium iodide is extremely diffusible and enters the 
blood with great rapidity. It acts in a general way as a 
tonic and stimulant to nutrition, accelerates tissue- 
changes, and increases the excretion of waste products. 
It has some slight diuretic action, and has the power of 
dislodging from the tissues various poisonous metallic 
substances, notably lead and mercury. 

The lymphatic glands are reduced in size by iodide of 
potash, and, like mercury, it has over some forms of dis- 
ease a marked and positive influence, not thoroughly 
explainable. Its action in these cases is called " specific " 
or " alterative." 

Incidental Effects. 

In giving any of the iodides, and especially the iodide 
of potash, the peculiar set of symptoms known as 
" iodism " must be carefully watched for. There is first 
an inflammation of the mucous membrane of the head 
resembling acute coryza, or catarrh ; running at the eyes 
and nose, salivation, swelling of the eyelids, sneezing, 
and frontal headache ; sore-throat, hoarseness, and trou- 
ble in swallowing, with a feeling of general wretchedness, 
and rise in temperature. 

There are also several varieties of eruptions which may 
appear, said to be more likely to occur in the case of 
patients with diseased kidneys. The most common is an 



$8 MATERIA ME D1C A FOR NURSE a. 

eruption of acne on the face, shoulders, and thighs, and 
eczema is also frequent. 

Debility and pains in the joints are sometimes noticed, 
and in some cases digestive disturbances result, with 
nausea and diarrhoea. 

The solution of i in i (Tit i. = gr. i.), is best given in 
milk ; or it may be given in cinnamon water, or the 
compound syrup of sarsaparilla, to disguise the unpleas- 
ant taste. It is often ordered with bichloride of mercury, 
and they may be given together, but if it is not ordered 
in combination it should never be added to any other 
medicine, but given alone. 

By largely diluting it and giving it on an empty stom- 
ach, symptoms of iodism are in a measure avoided. 

Dose, gr. v.- 3 i. (0.3-4. gm.) 

Liquor Iodi Compositus. 

Lugol's Compound Solution of Iodine. 

Composed of iodine and potassium iodide. Twenty 
minims contain gr. i. of iodine. 

Dose, Tit v.-xv. (TJ[ x. = gtt. x.), well diluted. 
(0.3-1. gm.) 

Tinctura Iodi. 
Tincture of Iodine. 

Contains 8 parts iodine and 92 parts alcohol. It is 
used externally as a counter-irritant ; applied with a 
camel's-hair brush, and in one or more coats as ordered. 
Each coat must dry separately. It cannot be diluted 
with water, as the iodine precipitates in water. If ex- 
treme burning follows the application, and it is desirable 
to wash it off, alcohol, or ether, or a solution of iodide 
of potash will remove it, or, still better, a weak solution 
of aqua ammonia. 

Unguentum Iodi. 
Iodine Ointment. 

Contains 4 parts in 100 of iodine, with one part of 
potassium iodide and benzoinated lard to make up the 
rest. 



NON-METALLIC ELEMENTS. 59 

Iodoformum. 
Iodoform. 
Iodide of Formyl. 

Iodoform is made by heating iodine with potassium 
carbonate, alcohol, and water, and allowing the crystal- 
line deposit to settle. It consists of small, bright-yellow, 
lustrous crystalline scales, with a very strong and clinging 
odor, and sweetish taste. It contains about 97 per cent, ©f 
iodine, and is freely soluble in oils, ether, and chloroform. 
It is slightly volatile at ordinary temperatures, and at 
a temperature above 239 F. emits vapors of iodine. In 
making sterilized iodoform gauze this iodine vapor will 
condense and turn the gauze brown unless free evapora- 
tion is allowed from the mouth of the jar or sterilizer. 

Iodoform was discovered in 1822, but was not used 
for some years. At various times since then its qualities 
have been referred to in medical articles, and within the 
last few years it has become very popular as an an- 
tiseptic in surgical dressings, — so much so that its use 
has been carried to excess and its reputation greatly 
exaggerated. Various cases of poisoning had the effect 
of checking its too lavish use, and its limitations as well 
as its powers are now more clearly known. 

It is no longer considered one of the most active 
germicides, as was claimed for a time, yet it has proper- 
ties sufficient to give it a secure place in surgery. It 
prevents or arrests decomposition, promotes union and 
cicatrization in wounds, and is a deodorizer. It is not 
irritating, but acts rather as a local anodyne. In a 
wound treated with iodoform the secretion is lessened, 
and is serous rather than purulent in character. In 
cases of poisoning by absorption through a wounded 
surface, the following symptoms may occur : 

Rise of temperature as high as 104 F., or higher. 
This may be the only symptom ; or with it there may be 
headache, a rapid and compressible pulse, and loss of 
appetite, the symptoms going off as soon as the iodoform 
is discontinued. Iodine is found in the urine in iodo- 
form poisoning. More serious effects are : a grave de- 
pression of the system, and anxious melancholia ; a 



60 MATERIA MEDIC A FOR NURSES. 

restless mental condition, with very weak and rapid 
pulse, perhaps reaching 180 ; drowsiness, delirium, and 
collapse. Death sometimes occurs quickly, even though 
the application be stopped. The amount capable of 
causing fatal poisoning has been recorded as varying 
from 500 grains upwards. In using iodoform the extent 
of exposed surface through which absorption may take 
place is of more importance than the actual amount ap- 
plied, which may not all be absorbed. 

Iodoform is sometimes given internally, in pill or 
capsule. Dose, gr. i.-ii. (0.06-0.13 gm.) 

Unguentum Iodoformi. 
Iodoform Ointment. 

Iodoform 10 parts, and benzoinated lard 90 parts. 

Iodol. 

Iodol is a new substance which has been chemically 
produced in the attempt to make an equivalent for 
iodoform, which should have its qualities without the 
unpleasant odor. It is obtained by the action of iodine 
on certain constituents of mineral oil, and contains about 
85 per cent, iodine. It is a yellowish-brown powder, 
which darkens on exposure to light. It is odorless, 
soluble in alcohol, ether, and chloroform ; iusoluble in 
water. It is said to be as efficiently antiseptic and 
disinfectant as iodoform, having the same deodorant 
and anaesthetic properties, but it is not much used. 

Other derivations of iodoform are : 

Aristol. Antiseptin. 

Europhen. Losophane. 

Antiseptol. Sozoiodol. 

Sozal. Sulphaminol. 
Thiophene. 

Sulphur (Brimstone). 

Sulphur is found native in volcanic districts as crude 
sulphur, and in combination with metals, as sulphides. 



NON-METALLIC ELEMENTS. 6 1 

Physiological Actions. 

Sulphur is used externally for its action on the skin. 
It has no local action of its own, but by contact with the 
products of the skin it changes into sulphuretted hydro- 
gen and sulphides, which are active substances. In this 
form it is a vascular stimulant, a nerve sedative, a 
stimulant to the skin, and a diaphoretic. 

Taken internally it acts as a laxative, increasing peri- 
stalsis, and it has also probably some power of influencing 
nutrition. 

If taken for a long time it impairs the blood and causes 
emaciation, anaemia, trembling, and debility. It forms 
sulphuretted hydrogen in the intestines, giving an un- 
pleasant odor to the faeces, and the same disagreeable 
odor is imparted to the perspiration, by the excretion of 
sulphur through the skin. Silver jewelry worn by a pa- 
tient taking sulphur becomes discolored by the excretions 
of the skin. 

Preparations of Sulphur. 

Sulphur Sublimatum. 
Sublimed Sulphur. 
Flowers of Sulphur. 

Prepared from crude sulphur (which compressed into 
molds forms the roll sulphur used in fumigating) by sub- 
liming. A yellow powder, tasteless, and odorless until 
heated, and insoluble in water. It always contains a 
little sulphuric acid, and is only used in making other 
preparations. 

Sulphur Lotum. 
Washed Sulphur. 

Sublimed sulphur washed with ammonia water and 
freed from acid. The action is laxative. It is given in 
powder mixed with simple syrup or molasses. Dose, 
3 i.-iii., given at night. (4.-12. gm.) 

Potassa Sulphurata. 
Liver of Sulphur. 



62 MATERIA MEDIC A FOR NURSES. 

Made by fusing sublimed sulphur with carbonate of 
potash. Solid greenish pieces, alkaline, and of very acrid 
taste ; soluble in water, making an orange-colored solu- 
tion. Locally applied, sulphurated potassa is an irritant, 
and taken internally is a violent corrosive poison. 
It is used in ointments and in giving sulphur baths ; in 
the latter case in a strength of from % i.-vi., to 30 gal- 
lons of water. The bath may last from twenty minutes 
to two hours, and has a generally stimulating effect. 

A papular eruption and eczema sometimes follow the 
use of sulphur. 

Unguentum Sulphuris. 

Sulphur in strength of 3 parts in 10, with benzoinated 
lard. 

Ichthyol. 

A preparation obtained from a bitumen ' found in the 
Tyrol, and supposed to be the residue of extinct fishes. 
It contains 10 per cent, of sulphur and is not irritating to 
the skin. It is used externally in an ointment of 10-20 
per cent, strength. 

Carbo (Carbon). 
Charcoal. 

Charcoal is obtained from the combustion of bones, — 
carbo animalis, animal charcoal, or bone black — and of 
wood — carbo ligni, wood charcoal. 

Charcoal absorbs and condenses many gases and vapors, 
coloring matters, alkaloids, and other substances in quan- 
tities many times greater than its own bulk ; and when 
exposed to the air it thus increases rapidly in weight. 
For this reason, when intended for medicinal purposes 
it must be kept carefully covered in well-stopped bottles. 

Externally it is used as an absorbent and deodorant, 
and internally as a carminative. It may be given be- 
tween two slices of bread and butter, or mixed with wine. 
Charcoal does not enter the system, but is entirely ex- 
pelled by the bowels. Dose, 3 i.- ? i (4.-32. gm.) 

1 An inflammable mineral substance. 



INORGANIC ACIDS. 6$ 

Aqua Hydrogenii Dioxidi. 

Solution of Hydrogen Dioxide. 

Peroxide of Hydrogen. 

A slightly acid watery solution of hydrogen dioxide, 
containing, when fresh, about 3 per cent., by weight, of 
the pure dioxide, corresponding to about ten volumes of 
oxygen. 

It is used in the treatment of ulcers, fetid suppura- 
tion, diphtheritic membranes, etc. Its virtues depend on 
its readiness to yield oxygen to all oxidizable substances. 

As it soon loses strength, it should be kept in small 
quantities, in a cool place, not exposed to the light, and 
*s it is an expensive article, should be carefully used. 

INORGANIC ACIDS. 

Acidum Sulphuricum (Sulphuric Acid). 

Oil of Vitriol. 

Sulphuric acid is made from the gas which is produced 
by the combustion of sulphur, by hydration on the action 
of steam. It is a colorless, oily-looking, intensely acid 
liquid, containing 2 per cent, water. On exposure to the 
air it absorbs moisture and becomes less dense. 

Physiological Actions. 

Sulphuric acid is a powerful corrosive, and abstracts 
water from animal and vegetable tissue, leaving carbon. 
It thus blackens organic matter while destroying its 
texture. 

Concentrated and mixed in a paste with charcoal, sul- 
phuric acid has been used as an escharotic. Diluted, 
its special action both externally and internally is that of 
an astringent. 

Symptoms of Poisoning. 

When swallowed in concentrated form it corrodes the 
alimentary canal, causing acute pain of the mouth, throat, 
and epigastrium. The tongue and lining of the mouth 
are whitened, like parchment, afterwards turning brown, 
while brown or blackened spots appear on the lips. 



64 MATERIA MEDICA FOR NURSES. 

There are : violent vomiting, of tarry matters often, 
cold extremities, and clammy skin ; profuse and bloody 
salivation, suppressed voice, and feeble pulse. The 
face expresses great suffering and anxiety. The mind is 
clear. The matters at first vomited are acid, and, if 
they fall on colored articles of dress the color is taken 
out, and the texture destroyed ; while on black material 
brown spots are produced, with an edge of red. 

There is sometimes perforation of the stomach or 
intestines. The symptoms come on immediately after 
the act of swallowing, and death may result in a few 
hours, but usually delays for from 18 to 24 hours ; oc- 
curring, finally, very suddenly. The smallest fatal dose 
recorded is 3 i. Usually f i. or more has been taken. 

Antidotes. 

The antidotes are chalk, magnesia, whitewash, or soap. 
They should be mixed in milk or water and given freely. 

Preparations. 

Acidum Sulphuricum Dilutum. 
Dilute Sulphuric Acid. 

Has a strength of 10 per cent, of the acid. 

Dose, Til x.-xxx. (Tlj, x. = gtt. x.) (0.65-2. gm.) 

Acidum Sulphuricum Aromaticum. 
Aromatic Sulphuric Acid. 

Contains alcohol and aromatics, and acid in a strength 
of 20 per cent. Both these preparations should be given 
well diluted, and through a glass tube, to save the teeth 
from injury. 

Dose, TTj, x.-xx. (TTJ, x. gtt. xxiv.). (0.65-1.3 gm.) 

Acidum Nitricum (Nitric Acid). 
Aqua Fortis. 

Nitric acid is prepared from nitre by distillation with 
water and sulphuric acid. A colorless, intensely acid, 
fuming liquid, containing 70 per cent, acid, the rest 
water. 

r 



INORGANIC ACIDS. 65 

Physiological Actions. 

It is a very powerful caustic, and if used in this way 
the sound tissues should be protected by a coating of oil 
or soap, or sheet-lint wet in a solution of bicarbonate of 
soda, and the spot cauterized be washed with warm soap- 
suds after sufficient effect has been obtained. 

Taken internally in medicinal doses it has stimulant 
and astringent properties. 

Poisoning and Antidotes. 

In concentrated form nitric acid is an exceedingly 
corrosive poison, even more violent than sulphuric 
acid. Like the latter, it destroys the membrane lining 
the mouth, oesophagus, and stomach. The symptoms 
are the same, except that nitric acid stains the tissues 
yellow instead of black. They come on with the same 
severity, and immediately. The antidotes are the same, 
and death occurs on an average in half a day, or a day. 

Preparations. 

Acidum Nitricum Dilutum. 
Dilute Nitric Acid. 

Has a strength of 1 part to 6. It must be well 
diluted and given through a glass tube. 

Dose, TT[ x. (Til x. = gtt. x.). (0.65 gm.) 

Acidum Hydrochloricum. 

Hydrochloric or Muriatic Acid. 

Hydrochloric acid is obtained by the action of sul- 
phuric acid on chloride of sodium, and solution of the 
fumes in water until it has a strength of about 30 per 
cent. An almost colorless, very acid liquid, with pun- 
gent odor. It is one of the natural acids of the stomach, 
and acts as a tonic on the glands of the alimentary 
canal, increasing the normal secretions. Its astringent 
properties are not marked. In concentrated form it is a 
corrosive poison, not as powerful as nitric or sulphuric 
acids. The symptoms and treatment are like the two 
others. 
5 



66 MATERIA MEDIC A EOR NURSES. 

Acidum Hydrochloricum Dilutum. 

Diluted Hydrochloric Acid. 

Has a strength of g iv. of the acid to one pint. 
Dose, TTt x.-xxx. (TT[ x. = gtt. x.), well diluted and given 
after meals. (0.65-2. gm.) 

Acidum Nitro-Hydrochloricum. 
Nitro-Hydrochloric Acid. 

Made by mixing three parts of nitric with five parts of 
hydrochloric acid. An orange-colored liquid, changing 
color in time, and more rapidly on exposure to light, to 
a light yellow. In medicinal doses the physiological 
effects are : stimulation of the liver specially, and also 
of the other glands of the alimentary canal. Besides 
being given internally, it is used in local applications to 
the liver, and in baths. In the former case, for stupes, 
the strength is 3 i.-iii. to O. i. of water ; and in the 
latter, \ i. to C. i. In poisonous doses the effects are 
the same as the other mineral acids. The stains it 
produces are yellow. The same antidotes are used as 
given before. 

In giving any of the mineral acids, the first symptoms 
of intolerance are : griping pains and diarrhoea, with 
strongly acid urine. These points are to be remembered, 
as well as the necessity for protecting the teeth. 
Acidum Nitro-Hydrochloricum Dilutum. 

Dose, TTj, v.-xx. (TT[ x. = gtt. x.), well diluted and 
given through a glass tube. (0.3- [.3 gm.) 

Acidum Phosphoricum. 
Phosphoric Acid. 

A colorless, odorless liquid, made by boiling phos- 
phorus with nitric acid and water, and having a strength 
of 66 per cent. It is very acid, but does not corrode the 
tissues. Its physiological effects are unimportant — 
mildly tonic and astringent. 



INORGANIC ACIDS. 6? 

Acidum Phosphoricum Dilutum. 
Diluted Phosphoric Acid. 

Dose, TTi xv - 3 ss. (tt[ x. = gtt. x.), well diluted. 
(-1.-2. gm.) 

Acidum Sulphurosum (Sulphurous Acid). 

Made by heating sulphuric acid with charcoal. Sul- 
phurous-acid gas results, and is dissolved in water, con- 
stituting 5 per cent, of the solution. A colorless liquid 
with pungent sulphurous odor. Sulphurous-acid gas is 
obtained by the combustion of roll sulphur, and is used 
in disinfecting rooms. Before the day of microscopical 
study this disinfection was believed to be complete ; but 
it is now known to have very little value where patho- 
genic bacteria are concerned. To be at all efficient it 
must be combined with steam. In Germany, sulphur 
fumigation after contagious diseases has been entirely 
discarded. It is, however, of real value in ridding a 
room or ward of bed-bugs, if these pests have lodged in 
the walls or woodwork, and for this purpose steam is not 
necessary. 

Acidum Boricum. 
Boric or Boracic Acid. 

Made by the action of sulphuric acid on borax, or by 
purification of native boric acid, which is a compound of 
the element boron with oxygen, and is obtained from 
certain mineral springs in Italy. White, pearly, glistening 
crystals, soluble in 25 parts of cold and 3 parts of hot 
water. The saturated solution has a strength of 4 per cent. 

Physiological Actions. 

Boric acid is antiseptic, disinfectant, and deodor- 
ant, destroying low organisms, and stopping fermenta- 
tion and putrefactive changes. 

It is not irritating externally, but rather the reverse, 
and when applied to wounds prevents suppuration. In- 
ternally, in large doses, it is a gastro-intestinal irri- 
tant, and poisoning has been caused by washing out 



6$ MATERIA MEDICA FOR NURSES. 

internal cavities with a 5 per cent, solution. The symp- 
toms were : nausea, vomiting, hiccough, disturbed 
respirations, rapid, feeble pulse, erythema and ecchy- 
mosis, subnormal temperature, and collapse. 

As a wash for babies' eyes and mouths, the saturated 
solution is diluted one half with water. 

It is used as the basis of a variety of mouth washes for 
the sick. It constitutes the largest part of Thiersch 
powder, used in making an antiseptic solution. (See 
salicylic acid.) 

Unguentum Acidi Borici. 

Contains white wax, paraffin, almond oil, and boric acid. 
THE ORGANIC ACIDS. 
Acidum Aceticum (Acetic Acid). 

Prepared from wood by destructive distillation and 
purification. A colorless liquid, with pungent odor and 
strong acid taste ; strength 33 per cent. ; the rest water. 

Glacial acetic acid has 99 parts acetic acid to 1 of 
water, and crystallizes at a temperature below 6o°. It 
is not officinal. 

Acidum Aceticum Dilutum. 
Diluted Acetic Acid. 

Has a strength of 1 part acid to 7 parts water. 

Acetum. 
Vinegar. 

An organic liquid containing acetic acid. It corre- 
sponds nearly in strength with the dilute acid. Vinegar is 
obtained from various vegetables and fruits by a process 
of fermentation known as the acetous or sour, as dis- 
tinguished from the vinous fermentation and others. 

Acetous fermentation may be induced in all liquids 
capable of undergoing vinous fermentation. 

The best vinegar is made from cider. It is often 
adulterated with sulphuric acid. 



THE ORGANIC ACIDS. 69 

Locally used acetic acid is a caustic. It is best 
applied with a glass rod, or a splinter of wood and needs 
to be applied with care to avoid injuring the surrounding 
parts. 

Diluted and applied to the skin, it is stimulant, as- 
tringent, and refrigerant, and in the form of vinegar 
is sometimes added to baths for the reduction of tem- 
perature. 

Internally it has a stimulating effect on the appetite 
and digestion ; increases the secretion from the intestines, 
and the flow of urine. It does not neutralize the alka- 
linity of the blood, but decomposes there, and combines 
with part of the alkali of the plasma, forming a car- 
bonate, and in this form passes out of the body, unless 
given in excess, when the excess escapes unchanged 
from the kidneys. In the alimentary canal the acid acts 
directly on its contents, and is given in the form of 
vinegar as an antidote for poisoning by alkalies. 

In concentrated doses acetic acid is a corrosive 
poison, and has caused death in one case known. 

The symptoms are like those of the mineral acids, and 
the treatment is the same, consisting in giving alkalies 
and their carbonates ; warm soapsuds, and milk. 

Acidum Citricum (Citric Acid). 

Citric acid is obtained from the juice of the lemon, 
citrus limonum, or of the lime, citrus bergamia, by 
neutralizing the boiling juice with chalk, and putting it 
through various processes. It is very soluble in water, 
and gr. xx. in 3 ss. of water makes a solution resembling 
lemon juice in strength and acidity. 

Citric acid, like the other free acids, acts directly on 
the contents of the alimentary canal, neutralizing alkalies. 

It is stimulant ; relieves thirst and promotes ap- 
petite ; increases the flow of the saliva and of the gastric 
juice ; and, indirectly, the action of the kidneys and 
skin ; hot lemonade especially being a diaphoretic. 

It is slightly laxative, and counteracts a tendency to 
torpidity of the liver. The juice of half a lemon, mixed 






/O MATERIA MEDIC A FOR NURSES. 

with that of an orange, is a satisfactory laxative drink in 
many cases. It is best taken before breakfast. 

In malarial countries lemon-juice is freely used as an 
article of food, and among sailors and soldiers it is used 
as a prophylactic against scurvy. 

Citric acid has no action on the sound skin ; it is but 
slightly irritating in large quantities internally, and is 
not poisonous. 

It may not be out of place here to refer to a popular 
error regarding a point of diet : that is, that a nursing 
woman may not drink lemonade because it will " sour 
the milk," and "give the baby colic." A nurse will 
probably often be appealed to on this subject. Her 
knowledge of the chemical facts : that citric acid is de- 
composed in the blood, forming a neutral salt ; that it 
does not reach the tissues as an acid, but passes out of 
the body as a carbonate, will at once decide the question. 



Acidum Tartaricum (Tartaric Acid). 

Tartaric acid is the acid of the grape, and is made from 
acid tartrate of potassium by a process similar to that 
used with citric acid. 

Its local action upon abraded surfaces, mucous mem- 
branes, or even the unbroken skin, is that of a decided 
irritant. Taken internally it is diuretic and slightly 
laxative, and somewhat depressing to the heart. 

Tartaric acid does not enter the tissues as an acid, 
but is decomposed in the blood, and passes out of the 
body as a carbonate. 

Poisoning and Antidotes. 

In large doses it is an irritant poison, causing burning 
pain of the oesophagus and stomach, vomiting, and 
gastro-intestinal inflammation, which may prove fatal. A 
dose of | i. has caused death in nine days. The alka- 
lies, magnesia, lime, soapsuds, or the alkaline carbonates 
are antidotes. 

Dose, gr. x.-xx., freely diluted. (0.65-1.3 gm.) 



THE ORGANIC ACIDS. 7 1 

Acidum Tannicum (Tannic Acid). 

There are two kinds of tannic acid, of which the 
official one is the gallo-tannic, and is obtained by treat- 
ing powdered galls with washed ether. (Galls are growths 
of plant tissue caused by parasitic fungi or insects, whose 
excretions stimulate the plant cells to an abnormal de- 
velopment. There are many hundred varieties ; that 
from which tannic acid is made being formed on an oak 
tree, Quercus lusitanica, by the action of the fly Cynips 
gallse tinctorise.) Tannic acid is a light, feathery, yellow- 
white, non-crystalline powder, of faint odor and slightly 
bitter taste. 
Physiological Actions. 

Locally applied it is an active astringent, contracting 
the tissues ; and in the case of mucous membranes, caus- 
ing great dryness. It coagulates albumen readily. It 
has much greater strength than gallic acid. It is used to 
overcome relaxed conditions, and to check excessive se- 
cretions of the skin and mucous membranes. Parts ex- 
posed to friction, as tender feet or sore nipples, may be 
successfully hardened by the use of tannic acid. It is 
also a haemostatic. 

It is the best chemical antidote for the poisonous alka- 
loids, but its administration should be followed by emet- 
ics and purgatives, as the compounds formed are capable 
of being dissolved and absorbed in the alimentary canal. 

When meant to act on the stomach it is usually given 
in powder ; on the bowels, in pill form ; and locally, as 
an ointment or lotion. 

Tannic or gallic acid in some form is contained in 
and gives character to nearly all of the vegetable astrin- 
gents, such as castanea or chestnut, catechu, geranium, 
pomegranate, logwood, hamamelis or witch hazel, kino, 
coto bark, alder, diospyros or persimmon, mango, pinus 
Canadensis, and others. 

Preparations. 

Glyceritum Acidi Tannici. 
Glycerite of Tannic Acid. 

Strength, 20 $. 



72 MATERIA MEDICA FOR NURSES. 

Unguentum Acidi Tannici. 
Tannic Acid Ointment. 

Strength, 20 <f>. 

Trochisci Acidi Tannici. 
Tannic Acid Troches. 

1 gr. each. 

Acidum Gallicum (Gallic Acid). 

Gallic acid is also made from galls, and is an astrin- 
gent similar to but milder than tannic acid. It does not 
coagulate albumen. 

It is given in powder and pill, in doses of from 10-30 
gr. (0.65-2. gm.) 

Acidum Lacticum (Lactic Acid). 

Lactic acid is found in sour milk. It is also produced 
by the action of a special ferment on sugar, and is one 
of the normal constituents of the gastric juice. It is a 
pale-yellow, syrupy, inodorous liquid, with acid taste. 

Lactic acid aids digestion and promotes appetite. 
It is credited with the power of dissolving fibrinous exu- 
dations, but its use as an application is very painful. 
Flatulence and epigastric pain result from its too free 
administration. 

It enters the blood as alkaline lactates, is decomposed, 
and excreted by the urine as carbonic acid. 

Acidum Lacticum Dilutum. 
Dilute Lactic Acid. 

Consists of 15 parts acid to 85 parts water. Dose, 
\ ss.-ii , well diluted. 

Acidum Hydrocyanicum. 
Hydrocyanic or Prussic Acid. 

The pure anhydrous 1 acid is a colorless, transparent, 
volatile, and inflammable liquid, so poisonous that its 
fumes alone will cause death. 

1 Without water. 






THE ORGANIC ACIDS. 73 

Its discoverer, Scheele, is supposed to have died 
from inhaling it. It is not official, and is only kept in 
laboratories. It is found in nature in a number of vege- 
table substances, viz., peach kernels, bitter almonds, 
wild cherry, cherry laurel, etc. 

Acidum Hydrocyanicum Dilutum. 
Diluted Hydrocyanic Acid. 

Made by distilling aqueous solutions of ferro-cyanide 
of potassium and sulphuric acid, and diluting the 
product with the water to the required strength. A 
colorless, watery liquid, containing 2 parts of the pure 
acid to 98 parts of alcohol and water. Its reaction is 
faintly acid ; the taste and odor like those of peach 
kernels and bitter almonds. Under the influence of 
light it has a tendency to decompose, and should be 
kept in dark-colored, well-stopped bottles. 

Physiological Actions. 

Applied to the skin the acid depresses the sensory 
nerves and causes numbness. It is therefore used for 
various local purposes, largely diluted, but should nevei 
be applied to an abraded surface, as, being readily 
absorbed, poisoning might result. 

It enters .the blood very rapidly, especially through 
the lungs, enters the tissues promptly, and acts chiefly 
on the nervous structures as a sedative and depres- 
sant. The respiratory centre is especially affected, the 
respirations weakened and slowed. The vaso-motor 
centre is stimulated temporarily, and then quickly de- 
pressed. The cardiac centre is also depressed, though 
it is the last to be affected. The sedative action of the 
drug is not confined altogether to the nerve-centres, but 
is shown also on the muscular structure of the hearr. 
The motor nerves and muscles are weakened by hydro- 
cyanic acid, the enfeebling action extending downward. 

It is very rapidly eliminated from the system, prob- 
ably by the lungs. This is not, however, a settled point. 
When taken in medicinal doses hydrocyanic acid causes 
a feeling of sleepiness. The first peculiar effects are : 
a bitter taste, an increased flow of saliva, and a feeling 



74 MATERIA MEDIC A FOR NURSES. 

of irritation and constriction of the throat. These effects 
pass off in half an hour or, at most, an hour. 

When the dose is rather larger than medicinal, viz., 
about TT[ xxx. of the weak acid, there may be noticed : 
nausea, transient giddiness, faintness, a feeble pulse, and 
general muscular weakness. Sometimes there is vomiting, 
or foaming and frothing at the mouth, with a suffused or 
bloated appearance of the face and prominent eyes. 

Symptoms of Poisoning. 

The inhalation of the vapor, short of a fatal quantity, 
causes giddiness, faintness, embarrassed breathing, a 
weak, small pulse, and even coma and insensibility, 
followed by recovery. 

If death results from small doses, there are commonly 
present tetanic spasms, lockjaw, and involuntary evacua- 
tions. 

Prussic acid is one of the most powerful poisons 
known, and after a toxic dose the symptoms come on 
instantly, and death may result in a few moments. 
Among its most marked effects are the insensibility and 
loss of muscular power, which are produced much more 
rapidly than by any other poison. 

There is usually loss of consciousness in a few sec- 
onds ; the eyes are protruding and shining, the pupils 
dilated and irresponsive to light ; the limbs relaxed and 
covered with clammy sweat ; the pulse imperceptible \ 
respiration very slow and convulsive, sometimes ster- 
torous, sometimes gasping, or sobbing, the act of expira- 
tion being long and forced, with a pause afterwards 
during which the patient seems dead. 

There is usually an odor of the acid on the breath. 
When the poisonous dose is small, yet still fatal, there 
are often convulsions, spasmodic clinching of the fingers, 
and contraction of the toes. 

The smallest fatal dose recorded was an amount 
equivalent to gr. yV of pure acid. This caused death in 
twenty minutes. Probably the average fatal dose is 
about gr. i. of pure acid, and the average time of death 
from two to ten minutes. It is not an accumulative 
poison. 






THE ORGANIC ACIDS. 75 

Treatment of Poiso?iing. 

There is no chemical antidote which acts quickly 
enough to. be of any service. Cold-water affusions to 
the head and spine, and artificial respirations, are of 
more service than anything else, and should be perse- 
vered in, especially the latter, as long as there is any sign 
of breathing ; as, if the tendency to death from apncea 
be combated until the influence of the poison begins to 
pass off, life may be saved. The stomach may be emptied 
by emetics or the stomach-pump ; inhalations of ammonia 
and chlorine water given ; and injections hypodermically 
of ammonia, ether, and alcoholic stimulants. 

Dose of dilute acid, TT[, i-iii. (TTL i. = gtt. i.). (0.06- 
0.2 gm.) 

Acidum Oxalicum (Oxalic Acid). 

Oxalic acid is never used in medicine, but, as a poison, 
it has caused accidental death so often that it will be 
included here. There are two forms of oxalic acid : 
one, the simple acid, which is found in sorrel and several 
other vegetable substances ; the other, the article known 
as essential salt of lemon, one of the most violent of the 
corrosive poisons, and often mistaken for Epsom salt. 

Symptoms of Poisoning. 

A hot, acrid taste, and burning in the throat and 
stomach ; intense abdominal pain, and vomiting of 
greenish, brown or bloody mucus of very acid reaction ; 
livid, cold skin ; small, irregular pulse ; unconscious- 
ness, stupor, and collapse. In some cases the gastric 
symptoms predominate, in others the nervous symptoms, 
as convulsions, numbness, paralysis, and stupor. 

The smallest fatal dose known is 3 i. An ounce usually 
proves fatal, and the symptoms appear immediately. 
Death may occur within a few minutes, or may be de- 
layed more than a week, and then take place from starva- 
tion resulting from the injuries to the intestinal canal. 

Treatment of Poisoning. 

The immediate administration of an antidote is of the 
greatest importance. Neither potash nor soda can be 
used, as their oxalates are poisonous ; but lime and chalk 



y6 MATERIA MEDIC A FOR NURSES. 

are perfect antidotes, and can be given as precipitated 
chalk or saccharated solution of lime, or they may 
be scraped off the wall, whitewashed fences, or ceilings, 
stirred up in milk, and freely administered. Emetics, 
followed by the soothing and demulcent drinks usual in 
the after-treatment of irritant poisons, are employed, and 
stimulants, with external warmth. 

THE CARBON COMPOUNDS. 
Alcohol. 

Alcohol is a product which results from a process 
of fermentation in substances containing grape-sugar — 
called the vinous fermentation in distinction from the 
acetous or vinegar-forming process. 

At a temperature of 8o° F., the presence and growth 
of the fermenting body (a low vegetable organism called 
the yeast-plant) converts a solution of grape-sugar into 
alcohol and carbonic acid. Starchy substances yield 
alcohol, starch being convertible into grape-sugar. 
From these vinous or fermented liquors alcohol is 
obtained by repeated distillation. It is also made syn- 
thetically, 1 by shaking olefiant gas (a gas composed of 
carbon and hydrogen, which is generally present in coal 
gas, oil gas, and other gaseous mixtures produced by 
the action of heat on organic substances) with strong 
sulphuric acid, diluting and distilling. Alcohol is a 
colorless, volatile liquid, of strong pungent odor and 
burning taste ; it is inflammable, burning without smoke 
and with a blue flame, evaporates on exposure to the air, 
is vaporized by heat, and unites readily with water in all 
proportions. 

There are three important alcohols or varieties of 
alcohol, viz. : 

i. Alcohol Ethylicum, Ethyl Hydrate, Grain 
Spirit. This is the alcohol of common language. 

2. Alcohol Amylicum, Amyl Hydrate, Potato 
Spirit, called fusel oil, and obtained also as an impurity 
in the production of ethylic alcohol by continuing the 
distillation after the pure spirit has ceased to come 
away. Amylic alcohol is not inflammable. 

1 By uniting elements into a compound. 



THE CARBON COMPOUNDS. J*] 

3. Alcohol Methylicum, Methyl Hydrate, 
Wood Spirit. Wood spirit is inflammable, and is 
cheaper than alcohol. 

Physiological Actions. 

Alcohol is locally antiseptic and disinfectant, 
cooling, and astringent. Internally, in medicinal 
doses it is pre-eminently a heart stimulant, and, in 
a lesser degree, a diuretic, diaphoretic, and anti- 
pyretic. 

Under certain conditions, it is a food ; under still 
others, a poison. 

When rubbed into the skin, as for the prevention of 
bed-sores, it disinfects and hardens it, checks the activity 
of the sweat glands, and irritates the cutaneous nerves, 
causing redness, heat, and local anaesthesia. Applied 
and allowed to evaporate, as in sponge baths, it has a 
cooling action. Coming in contact with an abraded 
surface it is very painful. It is absorbed by the un- 
broken skin. In the stomach it produces a sense of 
warmth, and, in moderate amount, stimulates the mucous 
membrane and dilates the small vessels, with the result 
that the blood supply is increased and the gastric secre- 
tions correspondingly abundant. 

When used in doses sufficient to give this result 
simply, alcohol is evidently favorable to digestion, but in 
larger quantities it has another and unfavorable action, 
namely, that of precipitating the pepsin of the stomach. 

Overdoses produce this result ; a small quantity, di- 
luted as it is by the gastric fluids, has not sufficient 
power to act on the pepsin to any marked degree. If 
alcohol is constantly used to excess, an abnormal secre- 
tion of mucus — gastric catarrh — results, with various 
evidences of dyspepsia, viz. : loss of appetite, acidity of 
stomach, heartburn and pyrosis, nausea, and morning 
vomiting. 

Other evidences of the alcohol habit are : constipa- 
tion ; pain on pressure over the stomach ; brown, dry 
tongue with red tip ; chronic pharyngitis ; fat, flabby, 
soft hands. 






78 MATERIA MEDICA FOR NURSES. 

Sleep, for the first part of the night, is sound, but is 
disturbed in the early morning, after which wakefulness 
remains, or broken sleep with bad dreams. 

Confirmed drinkers age fast. The skin becomes dry, 
and feels waxy, soft, and unhealthy. The mind becomes 
sluggish and weak, and cirrhosis of the liver and kid- 
neys, phthisis, epilepsy, paraplegia, insanity, and other 
disorders are among the sequels of alcoholism. 

Symptoms of Poisoning. 

A steady course of alcohol in excess, without taking 
food, will result in delirium tremens. Acute alcoholic 
poisoning presents the following symptoms : a short 
period of excitement, followed by coma ; respirations 
irregular, sometimes sighing but usually stertorous ; 
pupils either dilated or contracted, usually the former ; 
face flushed ; pulse hard, rapid, and strong. 

Acute alcoholic poisoning may be mistaken for opium 
poisoning, apoplexy, and compression of the brain. 

Death results from paralysis of the heart and respira- 
tions. The time at which death may occur varies from 
a few minutes to several days. 

The smallest known fatal dose was between § iii.-iv. of 
brandy swallowed by a child of seven years. 

Treatment of Poisoning. 

The treatment consists in emptying the stomach ; the 
application of heat to the extremities and cold affusions 
to the head ; the inhalation of ammonia, and the use of 
electricity applied to the respiratory muscles. 

Physiological Actions (Continued). 

Alcohol enters the blood unchanged or as aldehyde, 1 
and reaches the tissues and organs, a small portion being 
changed into acetic and carbonic acids. In its passage 
through the tissues it is oxydized, if given in moderate 
amount, and changed into carbonic acid and water, like 
other carbo-hydrates, — thus becoming a food or source 
of heat and force. 

i Alcohol deprived of a certain proportion of its hydrogen. 



THE CARBON COMPOUNDS. ?Q 

In a healthy adult, § iss. of absolute alcohol can be 
thus oxydized in twenty-four hours, and supplies to the 
organism as much heat and energy as is contained in the 
same amount of cod-liver oil or in about § ix. of beef. 

Beyond this, in health, it becomes injurious, and is 
eliminated by the kidneys, skin, and lungs ; though in 
different morbid states large — even excessive — quanti- 
ties can be safely taken. 

Children and old people bear alcohol well. 

Although alcohol is itself oxydized, it interferes with 
the oxidation of other substances, thus saving the tissues 
from wear and retarding the process of waste. 

This, joined to its stimulating action on the circulation 
and on the nervous system, gives it the power of sustain- 
ing life for a time, under the strain of acute exhausting 
disease, or during a period of temporary inability to take 
sufficient food. 

Its stimulant effect is shown on the heart by an in- 
crease in the strength of the contraction or systole. The 
pulse becomes strong and regular, full, and compressible. 
If it had, before, been rapid and weak, it will, under the 
favorable influence of alcohol, become reduced in fre- 
quency to near the normal ; but, if over-stimulated, this 
shortening of the period of rest will in time exhaust the 
heart. 

In giving alcohol as a medicine, it is important to be 
able to recognize the first evidences of over-stimulation 
as given by the pulse. 

The " whiskey pulse " as it is called, is unnaturally 
strong, full, frequent, and bounding. 

On the brain and nervous system alcohol acts as a 
stimulant, up to a certain point ; beyond that, as a de- 
pressant and narcotic. 

On the circulation and bodily heat its action would, at 
first sight, seem to be contradictory. The sense of 
warmth given by a dose of alcohol seems incompatible 
with the well-proved facts that the bodily heat is, on the 
whole, lowered by alcohol, and that the power of resist- 
ance to cold is weakened by its use. 

The physiological explanation is, that the blood-vessels 



80 MATERIA ME DIC A FOR NURSES. 

are dilated by the stimulus of alcohol, — the blood rushes 
to the surface to fill the superficial vessels, and a feeling 
of warmth results, which, in a warm or moderately cool 
atmosphere, remains, and promotes the general comfort ; 
but, in a cold atmosphere, the supply of blood to the sur- 
face being so much larger than ordinary, and perspira- 
tion being also increased, while active tissue-changes are 
checked, heat is abstracted from the body by evaporation 
at a rate which soon affects the vital powers seriously. 

In giving stimulants there are various points to notice 
by which to judge whether it is doing good or not. 

The pulse has been mentioned ; the tongue gives 
another indication. If a dry tongue becomes moist un- 
der the influence of alcohol, it is acting well ; if the dry- 
ness of the tongue be increased, it is not, and the same 
rule applies to the skin. If nervousness is quieted, sleep 
induced, delirium and subsultus lessened by alcohol, it is 
acting favorably ; if restlessness and uneasiness follow, or 
increased delirium, or sleeplessness, — unfavorably. 

In cases of sudden heart failure alcoholic stimulants are 
given hot and concentrated. 

Preparations of Alcohol. 

Spiritus Rectificatus. 
Rectified Spirit. 

Contains 85 per cent, of pure ethyl alcohol with 15 of 
water. 

Absolute Alcohol. 

Made from the rectified spirit by a lengthy chemical 
process. It consists of 99 parts pure alcohol with 1 of 
water, and is not kept for sale but used only for pharma- 
ceutical purposes. 

Spiritus Tenuior. 
Proof Spirit. 

Equal parts of alcohol and water, or, strictly speakings 
49 per cent, alcohol. 



THE CARBON COMPOUNDS. 8 1 

Alcohol Dilutum. 
Dilute Alcohol. 

Equal parts of alcohol and water. 
Alcohol. 

Contains of absolute alcohol 94 parts by volume (91 

parts by weight). 

Alcoholic Beverages. 

Spiritus Frumenti. 
Whiskey. 

Made in the United States from rye and corn, in 
Scotland from barley, and in Ireland from potatoes. 

It has from 44 to 50 per cent, by weight of ethyl alco- 
hol (by volume 50 to 56 per cent.), and contains ethers 
which are developed in the course of its fermentation ; 
and, even in the best varieties, some traces of fusel oil. 
Whiskey should be at least two years old before it is used. 

It is sometimes necessary or convenient to use alcohol 
instead of whiskey. The ordinary dose of § ss. whiskey 
is represented by a little over 3 ii. of alcohol, or by J ss. 
of dilute alcohol. 

Spiritus Vini Gallici. 
Brandy. 

Brandy should be distilled from grapes, but it is also 
made artificially. It has about the same percentage of 
alcohol as whiskey. It may be* either pale or dark ; in 
the former case it is colored by the cask, in the latter it 
contains caramel. It should be at least four years old. 
Brandy has a more sedative action on the stomach than 
whiskey, and is preferable where there is any tendency to 
diarrhoea, as it is slightly constipating, containing a little 
tannin. Both brandy and whiskey are more easily taken, 
as medicines, if poured over a small glassful of cracked 
ice ; or they may be diluted with carbonated or seltzer 
water more acceptably than with plain water. Giving 
them in milk very often causes patients to take a dislike 
to the milk. They are both used hypodermically, and foi 
this purpose should always be filtered. 



82 MATERIA MEDIC A FOR NURSES. 

Rum, 

Made by the distillation of fermented molasses. 

Gin. 

Distilled from rye or barley, and flavored with juniper 
berries. If it is pure, it is an efficient diuretic, owing to 
the oil of juniper, but it is rarely pure. 

Wines. 

Official wines are white wine, vinum album, and 
stronger white wine, vinum album fortius. They are 
used in medicinal preparations. White wine contains 
about jo per cent, of alcohol, and is made from grape 
juice without skins, stems, or seeds. 

All wines contain various acids and traces of mineral 
substances. Those which are free from sugar are called 
" dry " wines. 

The red wines — claret, port, etc., are made from col- 
ored grapes with the skins, and have considerable alco- 
holic strength. Port wine, vinum portense, contains from 
30 to 40 per cent, of alcohol, but is rarely pure. 

As stimulants and in narcotic power these wines 
stand next to brandy and whiskey. They contain some 
tannic acid and are astringent, causing constipation 
and disordering the stomach. They also tend to raise 
the temperature. 

Vinum Xericum, or sherry, belongs to the dry spiritu- 
ous wines. It contains 17 per cent, of alcohol, and is 
usually made artificially. It assists digestion if taken 
during meals. 

Sparkling wines, of which champagne is the most im- 
portant, are bottled before fermentation is complete, and 
are effervescent, being charged with carbonic acid. They 
are more intoxicating" than others in proportion to their 
strength, are less stimulating to the heart, and liable 
to leave headache and sour stomach as after-effects when 
freely taken. In small doses they are gastric seda- 
tives, champagne especially being so. Given ice-cold 
and in teaspoonful doses, at short intervals, it may be 



THE CARBON COMPOUNDS. 83 

retained by an irritable stomach which rejects every 
thing else. In giving champagne in this way care is 
necessary to prevent escape of the gas and flattening of 
the wine. A champagne tap is used, and the bottle held 
head downward. In the intervals it is kept on ice in the 
same position. 

Sweet wines, including Burgundy and Madeira, are 
rather trying to the digestion. They disorder the stom- 
ach and cause headache. They contain 6 or 7 per cent, 
of alcohol. 

Dry acid wines, — the German and some of the French 
wines, are stimulant, and do not cause acid fermentation. 
They contain from 5 to 7 per cent, of alcohol. 

Beer, Ale, Porter, Stout, 

Contain from 2 to 6 per cent, of alcohol ; also extract 
of malt, lactic acid, salts of potash and of soda, and 
aromatics. 

Chloroformum (Chloroform). 

Chloroform is made by the action of chlorine on 
alcohol. 

Physiological Actions. 

Externally applied and allowed to evaporate, chloro- 
form causes a sense of coldness and depresses the termi- 
nations of the sensory nerves, acting as an anodyne and 
producing insensibility to pain. If evaporation is pre- 
vented it irritates, reddens, and blisters the skin. These 
effects are followed by anaesthesia of the part. Given 
by mouth, chloroform has a hot, sweet taste, and in the 
stomach produces a feeling of warmth. In large quanti- 
ties or undiluted it causes violent gastro-enteritis. Me- 
dicinally it is given as an antispasmodic, anodyne, 
and carminative. It enters the circulation through the 
lungs, stomach, and unbroken skin. It reaches the tis- 
sues very rapidly, and exerts its greatest power on the 
central nervous system. It is excreted partly as chloro- 
form by the kidneys, lungs, mammary glands, and skin, 
and part is lost in the system. 



84 MATERIA MEDIC A FOR NURSES. 

Symptoms of Poisoning. 

In poisoning by chloroform taken internally the symp- 
toms are stupor ; cold skin covered with perspiration ; 
pulse slow, thready, sometimes almost imperceptible ; res- 
pirations at first stertorous, afterwards becoming shallow, 
irregular, and infrequent. The symptoms come on almost 
immediately after it has been swallowed, and death may 
result in a few hours, or may result after a longer time 
from gastro-enteritis or from inflammation of the trachea. 

Treatment of Poisoning. 

There is no antidote for chloroform, on account of its 
extremely rapid diffusibility through the system. The 
stomach must be emptied, washed out, if necessary, and 
cold-water affusions applied to the head, and plenty of 
fresh air admitted. Artificial respiration should be prac- 
tised steadily and unremittingly. 

The smallest fatal dose recorded is 3 ii. 

Dose of chloroform, TT], xv.-xxx. (TT[ x. = gtt. lx.). 
(1.-2. gm.) 
Spiritus Chloroformi. 

Strength, 10 <f>. 

Dose, 3 ss.-i., well diluted. (2.-4. gm.) 
Emulsum Chloroformi. 
Chloroform, 8 <f . 
Dose, J ss. (32. gm.) 

Chlorodyne. 

A proprietary medicine containing chloroform, ether, 
morphia, cannabis indica, and hydrocyanic acid. 

Dose, TT1, v.-xxx. ( TTL x. = gtt. xx.), well diluted. 

(0.3-2. gm.) 

Linimentum Chloroformi. 
Chloroform Liniment. 

Composed of soap liniment and chloroform. 

Linimentum Chloroformi Compositum. 
Compound Chloroform Liniment. 

Contains chloroform, oil of turpentine, laudanum, 
tincture of aconite, and soap liniment. 



THE CARBON COMPOUNDS. 85 

In the use of the vapor of chloroform as an anaesthetic 
there are three stages of narcosis : the first, a short 
period of excitement during which the sensibilities are 
blunted, though consciousness is not lost ; second, the 
stage of anaesthesia. Consciousness and sensibility are 
abolished ; the pulse is about normal in frequency and 
slightly weaker ; respiration slow, heavy, and stertorous. 
During this period operations are performed. The third 
stage is a dangerous one, with profound narcosis ; entire 
muscular relaxation ; stertorous breathing, gradually be- 
coming sighing and weak ; and complete abolition of 
reflex actions. 

Chloroform is preferred to ether in some cases because 
it is easier and pleasanter to take ; is more prompt in its 
action ; is not so nauseating, and its after-effects pass 
away more quickly. In obstetrical cases it is preferred 
because by its use a state of insensibility to pain can be 
produced without bringing on complete muscular relax- 
ation, which would delay labor. 

No fatal cases are known to have occurred in parturi- 
ent women, although in surgical cases death has occurred 
quite frequently and with great suddenness, from paraly- 
sis of the respirations and heart, and ordinarily chloro- 
form is considered much less safe than ether. In giving 
chloroform to a patient in labor (which a nurse may be 
required to do), the face must first be oiled with vaseline 
to prevent any possibility of blistering. 

About 3 ss. of chloroform is poured at one time on a 
sponge, or piece of lint, and held before the nose in a 
way that will allow plenty of air to mix with it, as the 
chloroform should only be in a strength of 3 per cent, 
with the inspired air when inhaled. 

It is only to be inhaled during the existence of a pain, 
and not in sufficient quantity to lessen uterine contrac- 
tion. If the pulse weakens, the respirations grow shal- 
low, or the pains become insufficient it is stopped. 

It is well to keep the supply safely out of reach in the 
case of excitable and hysterical patients. 

In the treatment of poisoning by inhalation of chloro- 
form vapor, the head is lowered to an angle of about 40° 



86 MATERIA MEDICA FOR NURSES. 

Plenty of fresh air is needed, and should be warm, about 
8o°-85° F. External heat must be applied, inhalations 
of nitrite of amyl may be used, and artificial respiration 
kept up for several hours. 

iEther (Ether). 
Ethyl Oxide. 

A colorless, volatile liquid, made by the action of sul- 
phuric acid on alcohol, by a very elaborate process. It 
evaporates rapidly on exposure to the air, and is very 
inflammable, as is also the vapor. The odor is very 
strong, heavy, and peculiar. 

Physiological Actions. 

Applied to the skin and allowed to evaporate, ether is 
a refrigerant and local anaesthetic of such power that 
minor surgical operations are sometimes performed 
under its local influence ; the part to be operated on — 
as, for instance, a finger — being sprayed with ether until 
benumbed, a process which only requires a few moments' 
time. 

Internally it has a strong burning taste, is irritant to 
mucous membrane, and causes salivation through reflex 
action. In the stomach it acts as a local stimulant and 
carminative, and also, by reflex action, as a stimulant 
to the heart, respiratory organs, brain, and intestines. 

It is an antispasmodic, anthelmintic, and dia- 
phoretic. When inhaled it first produces a strong 
irritation of the throat, with a strangled feeling. The 
cerebrum is first affected by the use of ether as an anaes- 
thetic ; the sensory and motor nerves next ; the centres 
of respiration and circulation in the medulla are the last 
to become influenced, and continue to act, unless the 
anaesthetic is pushed too far, when the respirations die 
away, the heart continuing to beat after breathing has 
stopped. 

The state of the bladder must be carefully watched in 
all cases after etherization, as there is often retention of 
urine. External heat must be plentifully supplied, and 



THE CARBON COMPOUNDS. 87 

the facility with which an insensible patient may be 
seriously burned by hot-water bottles and bags should be 
constantly kept in mind. The effects of the ether are 
allowed to pass off quietly of themselves, plenty of fresh 
air being secured, any effort at vomiting being best over- 
come by giving a teaspoonful of very hot water at inter- 
vals. If there is no tendency towards collapse, cracked 
ice in small quantities may be used. 

In preparing a patient for etherization, definite orders 
from the surgeon are always received, and it is only 
necessary here to speak of the absolute importance of 
having the stomach, bowels, and bladder entirely empty. 

Death from strangulation may be caused by a fragment 
of vomited food lodging in the windpipe, and the bowels 
and bladder, if not thoroughly attended to, will empty 
themselves spontaneously. 

Ether is excreted like chloroform, and rapidly. The 
anaesthetic mixture of Nussbaum is formed of ether 3 
parts, alcohol and chloroform each 1 part. 

Preparations of Ether. 

Spiritus iEtheris. 
Spirit of Ether. 

Has 30 parts of ether and 70 of alcohol. 

Dose, 3 i., well diluted with cold water. (4. gm.) 

Spiritus iEtheris Compositus. 
Compound Spirit of Ether. 
Hoffman's Anodyne. 

Contains 30 $ ether, with alcohol and ethereal oil. It 
is a carminative, antispasmodic, and stimulant. 
Dose, 3 i.-ii., diluted with very cold or iced water. 
(4.-8. gm.) 

Spiritus Athens Nitrosi. 
Spirits of Nitrous Ether. 
Sweet Spirit of Nitre. 

A solution of nitrous ether in alcohol, made by 
adding sulphuric and nitric acids to stronger alcohol, 



88 MATERIA MEDICA EOR NURSES. 

adding also some copper wire, and distilling. Sweet 
spirit of nitre is volatile and inflammable. It should 
not be kept long, as it becomes acid with age. It 
is a diuretic and diaphoretic, acting by relaxing and 
dilating the renal and cutaneous vessels. It is also a 
nerve sedative and antispasmodic. 

The action on the skin is made more prominent 
by keeping the patient warmly covered in bed, and 
on the kidneys when kept cool, or out of bed. Like 
all preparations of ether it should be largely diluted and 
given very cold, as this lessens the strangling feeling in 
the throat. 

The inhalation of sweet spirit of nitre has caused 
alarming symptoms— viz. : pallor, weak pulse, muscular 
weakness, pain about the heart, and headache. 

Taken internally, in large quantities, it has in one 
or two instances caused death. 

Dose, 3 i.- 1 ss. (4.-16. gm.) 

Preparations of ether are given hypodermically as 
heart stimulants, and should be injected deeply into the 
muscular tissues to avoid irritation and formation of 
abscesses. 



Chloral. 



Chloral is an oily, colorless fluid, made by the action 
of chlorine on alcohol. It is not used in medicine. 
United with water it forms a hydrate which is the 
chloral of the U. S. P. 



Chloral Hydras. 
Chloral Hydrate. 

Colorless, volatile crystals of hot burning taste and 
pungent odor ; readily soluble in water, ether, or al- 
cohol. 



THE CARBON COMPOUNDS. 89 

Physiological Actions. 

Chloral has antiseptic properties and has been so 
used in a strength of gr. v.- 3 i. of water. A concentrated 
solution vesicates and is very painful. 

Given internally it acts on the nerve centres as a 
sedative, its effect on the brain, under suitable con- 
ditions, being that of a pure and perfect hypnotic. The 
sleep it causes resembles natural sleep, coming on quickly 
and lasting for six or seven hours. The patient may be 
aroused from it for medicine or nourishment, and falls 
asleep again, finally awaking refreshed, and without 
headache or the unpleasant after-effects — such as nau- 
sea, giddiness, and constipation — which are commonly 
found after taking opium. Even if given for a long time 
chloral is not apt to cause constipation or disturbance of 
the stomach. 

In the sleep of chloral the pupil is slightly contracted, 
the pulse unaltered or a little slower than normal, the 
respirations regular, full, and quiet. The cases in which 
its beneficial action are best seen are cases of insomnia 
from mental labor, anxiety, or fatigue. It is not an 
anodyne, having no power to overcome pain unless given 
in dangerous doses. If so given the after-effects are bad. 

The action of chloral is not always satisfactory. With 
some persons headache, excitement, and even delirium, 
are caused by medicinal doses. 

Symptoms of Poisoning. 

In larger doses the respiratory centre is depressed and 
the respirations become slow, irregular, and shallow. The 
activity of the vasomotor centre is lessened, so that the 
vessels dilate generally, and the heart is depressed and 
weakened not only through the centre in the medulla 
but also by a direct influence on its own nerve ganglia. 

The pulse becomes weak and slow ; in toxic doses it 
grows rapid and irregular, and in fatal cases feeble and 
thready, while other symptoms are coma, great muscular 
relaxation, pupils at first contracted, afterwards dilated, 
and death results from paralysis of the respirations and 
heart. 



90 MATERIA ME DIC A FOR NURSES. 

Treatment of Poisoning. 

The treatment in chloral poisoning consists in the use 
of alcoholic stimulants, strong coffee, galvanism, and 
artificial respiration. The application of external heat 
is of the utmost importance. Mustard pastes and hot 
mustard foot-baths may be used, avoiding, however, all 
measures which might exhaust the patient. 

Incidental Effects. 

There may be noticed after ordinary doses of chloral, 
dyspnoea ; redness and swelling of the conjunctivae ; and 
eruptions of the skin, most frequently a simple erythema 
which seems to follow preferably the course of the large 
nerve trunks. Sometimes the eruption takes the form 
of wheals, and a papular eruption has also been ob- 
served. These disorders are often attended by some 
rise of temperature, and desquamation sometimes results. 
It is supposed that they, as well as the more alarming ill 
effects of chloral, are greatly, if not altogether, due to 
impurities of the drug. 

The great danger of chloral is the sudden paralysis of 
the heart, which may occur even after ordinary medici- 
nal doses, and without warning. This attaches so much 
uncertainty to its action that it is impossible to express 
caution too strongly in regard to using it without orders. 
The patient may be sleeping quietly, but suddenly be- 
comes restless and passes into a state of syncope. The 
danger cannot be considered past until from 60 to 100 
pulse beats can be counted continuously without any 
irregularity in strength. 

The habitual use of chloral may become a disorder 
almost as grave as the opium habit. Those who have 
formed this habit are usually excitable in manner ; hur- 
ried and voluble in speech ; nervous and wakeful at 
night ; melancholy and low-spirited during the day, and 
subject to vertigo and ringing in the ears. 

The eyes are brilliant and restless ; the appetite capri- 
cious or lacking altogether ; digestion disordered ; the 
heart action weak and irregular, and the secretion of bile 
deficient. 



THE CARBON COMPOUNDS. 9 1 

Dose, gr. v.-xx., diluted only moderately with water 
or a weak syrup. (0.3-1.3 gm.) 

Butyl Chloral Hydrate. 
Croton Chloral. 

A crystalline body formed by the action of chlorine on 
aldehyde ; sparingly soluble in water, readily so in 
glycerine. It is said to resemble chloral in its action, 
but to be more depressing and less efficient. A feebler 
poison, more disagreeable in taste, and having a special 
anaesthetic effect on the fifth nerve. 

Dose, gr. v.-xx., in syrup or glycerine. (0.3-1.3 gm.) 

Metachloral. 

A solid substance prepared by acting on chloral 
hydrate with sulphuric acid, and used as a counter- 
irritant and local anaesthetic. 

Chloral Camphor. 

Equal parts of camphor and chloral, used as an ex- 
ternal application for the relief of pain. 

Paraldehydum (Paraldehyde). 

Paraldehyde is a colorless liquid solidifying below 
50 F., and soluble in ten parts of water. It has 
a strong ethereal odor and unpleasant taste. It is 
a pure hypnotic, like chloral, having about half its 
power and many of its qualities without the dangers 
of chloral. 

In its action the cerebrum is first affected, and 
sleep induced with no primary stage of excitement. 
The medulla is next affected, and next the spinal 
cord. It has little or no control over pain. In 
medicinal doses it is not paralyzing to the heart, and 
does not, as, a rule, leave headache or unpleasant 
after-effects. 

It is irritant to nvucous membrane, and is likely in 



92 MATERIA MEDIC A FOR NURSES. 

time to impair digestion. It gives an unpleasant odor to 
the breath, and if used for a long time it may produce 
nasal ulcers, cerebral congestion, and vasomotor paralysis 
It sometimes causes erythema or reddening of the skin. 

Dose, TTj, xxx -3 i. ( TTL x. = gtt. xxv.), in water, either 
plain or with simple syrup. It must be well diluted. 
(1.3-2. gm.) 

Sulfonal. 

Sulfonal is an alcohol derivative, belonging to what 
are chemically known as the sulphur compounds of 
alcohol. It has hypnotic action. It is a white, odor- 
less, and tasteless powder, almost insoluble in water, 
requiring from 100 to 150 parts of cold, and 18 or 20 of 
boiling, water to dissolve it. 

In favorable instances it produces a physiological 
sleep, which lasts for several hours, with no unpleasant 
after-effects. With susceptible cases sleep has been 
known to come on in an hour or little over, but as a 
usual thing sulfonal is rather slow in action, sometimes 
not taking effect for several hours, sometimes even not 
until the next day ; and in these delayed cases^ sleep, 
when it does come, is prolonged and dull. In a certain 
number of cases sulfonal fails to act satisfactorily, and, 
in these, nausea, mental excitement, vomiting, dizziness 
and staggering, headache and depression have been ob- 
served after its use. 

It may be given dry on the tongue, but is best given 
in hot milk, or soup, or beef-tea, with plenty of salt. 
Large amounts of warm fluids favor its absorption, and 
as it is often slow in action it is better given early in the 
evening. Dose, gr. xx.-xxx. (1.3-2. gm.) 

Hypnone. 

A new hypnotic, produced chemically as a derivative 
of alcohol. A colorless liquid having a strong odor of 
almond or orange. It is not dangerous, and leaves no 
ill after-effects except a disagreeable odor to the breath. 

Dose, TT[ v.-x., in capsule, being insoluble in water. 
(0.3-0.65 gm.) 



THE CARBON COMPOUNDS. 93 

Urethan. 

A combination of carbonic acid and ethylic ether, 
lately introduced as a hypnotic. Its action is rather 
uncertain, and resembles paraldehyde. It has no power 
over pain, is not depressing or irritating to the stomach, 
and under favorable circumstances has induced sleep 
in 15 or 20 minutes, and prolonged it for 6 or 8 hours. 
It is soluble in water, and may be given hypodermically, 
as it is not irritating. 

Dose, gr. x.-lx., best given in pellet, wafer, or capsule. 
(0.65-2.6 gm.) 

Amylene Hydrate. 

An alcohol derivative, with properties as a hypnotic, 
its power being considered intermediate between chloral 
and paraldehyde. It is a clear liquid, soluble in 8 parts 
of water, and readily so in alcohol. It is agreeable to 
the taste and not dangerous, having, in medicinal doses, 
no depressing effect. Very large doses paralyze the 
respiratory centre, and also the heart. 

Dose, 3 i.-iss. (4.-6. gm.) 

Amyl Nitris (Amyl Nitrite.) 

Amyl nitrite is produced by distilling nitric acid with 
amylic alcohol (fusel oil), sulphuric acid, and copper, 
and purifying with alkalies by various intricate pro- 
cesses. An ethereal liquid of yellow color and fruity 
odor. 

It is given by inhalation usually. The vapor enters 
the blood through the lungs with extreme rapidity, 
reaching the tissues and producing its characteristic 
effects almost instantaneously. 

Amyl nitrite is a motor depressant. Its leading 
physiological action is upon the spinal cord and the cir- 
culation, other effects being secondary. The motor 
centres in the cord are directly and strongly depressed v 
and a similar but less powerful action is exerted on the 
motor nerves and muscles. The sensory nerves are but 
little affected. 



94 MATERIA MEDIC A FOR NURSES. 

Two effects are produced on the circulation. First, 
the muscular walls of the arteries are paralyzed ; the 
vessels dilate, and the blood pressure falls. Second, b^ 
this reduction of the blood pressure the resistance which 
was met by the left ventricle in discharging its contents 
disappears, with consequent relief to the heart, which has 
at once less work to do, with the same, or increased 
strength, to do it. The heart-beats are increased in 
number — not always in force, — and the depression of 
the inhibitory apparatus gives the beats an energetic and 
thumping character. 

In this way amyl nitrite acts as a heart Stimu- 
lant, not by actually strengthening the heart itself, but 
by clearing away obstructions to a free circulation which 
increased the work of the heart and exhausted it by com- 
pelling it to put forth abnormal exertions. 

From 2 to 5 drops, inhaled, will give this result, with 
the attendant symptoms of fulness and throbbing of the 
head, amounting sometimes to severe pain. 

If inhalation is carried beyond this there will be ver- 
tigo ; flushing of the face, with visible pulsation of the 
carotids ; deep, labored respiration ; tingling of the sur- 
face ; dilatation of the pupils ; restlessness and anxiety. 
These symptoms disappear rapidly on the withdrawal of 
the drug, and the heart-beats fall to normal. 

It is stated that all objects look yellow to one fully 
under the influence of amyl nitrite. 

Larger doses increase all these symptoms in severity, 
to the point of grave depression, with cold extremities ; 
heavy clammy perspiration ; slow, almost imperceptible 
pulse ; irregular respirations ; and severe persistent head- 
ache. There may sometimes be convulsions. Toxic 
doses paralyze the heart and respiratory centres. In 
cases of poisoning by amyl nitrite all the blood of the 
body becomes a uniform hue, which is described as being 
nearer a chocolate color than ordinary venous blood. 

The poisonous dose is not certainly known. A dessert- 
spoonful taken internally has been recovered from, by 
the aid of emetics, and hypodermically 3 ii. have been 
given in an hour and a half without unpleasant symptoms. 



THE CARBON COMPOUNDS. 95 

In giving inhalations of amyl nitrite, from 3 to 5 
drops are placed on a handkerchief, or piece of lint or 
cotton, held near the nose, and withdrawn as soon as 
fulness in the head or flushing of the face is produced. 
The symptoms usually are a little more prominent for a 
moment or two after the drug has been withdrawn. It 
has been given hypodermically and also by mouth. In 
the latter way the dose is Til ii.-iii. on sugar (t\[ x. = gtt. 
xxx.). (0.1-0.18 gm.) 

Amyl nitrite escapes by the kidneys. The urine is 
increased in amount and in acidity, and may sometimes 
contain sugar. 



Nitro-Glycerinum (Nitro-Glycerin), Trinitrin, 
Glonoin. 

Made by dropping glycerin in a mixture of sulphuric 
and nitric acids kept ice-cold ; separating by pouring 
the product into water, washing, and evaporating to a 
proper density. A colorless, oily liquid, odorless, with 
sweet, pungent taste ; slightly soluble in water and freely 
so in oils, alcohol, and ether. 

If heated in a close vessel, or if subjected to percus- 
sion, it will explode* Mixed with porous silica, nitro- 
glycerin constitutes dynamite. It is never used undiluted 
in medicine. 

Spiritus Glonoini. 

Spirit of Glonoin, or Nitro-Glycerin. 

A one-per-cent alcoholic solution of glonoin. It should 
be kept cool, away from lights or fire. 

Physiological Actions. 

Nitro-glycerin is the most powerful of the nitrites. 
Its physiological actions resemble very strongly those of 



g6 materia medic a for nurses. 

amyl nitrite but in a greater degree, and the effects, 
while less prompt in appearing, are more lasting, being 
developed in from three to five minutes, and continuing 
for about forty-five minutes. 

Depression of the motor centres, dilatation of the 
blood-vessels, and lowering of the blood pressure are the 
chief factors in the action of nitro-glycerin. The first 
signs manifest are perspiration and quickened heart 
action, with, sometimes, a dicrotic pulse ; disturbed 
respiration, flushed face, vertigo, constriction of the head 
and throat, occasional nausea, throbbing of the carotids, 
and headache, which is of a severe frontal type, and lasts 
sometimes for hours after other effects have worn away. 
In some cases albumin in the urine is diminished by 
nitro-glycerin. 

Symptoms of Poisoning. 

Poisonous doses cause heart failure, with slow, inter- 
mittent, and very irregular pulse ; dilated pupils ; a 
feeling of weakness in the epigastrium ; and intense 
headache, with a feeling as of a tight band around the 
head. 

Symptoms of poisoning not resulting in death have 
followed doses of from two to ten drops of the alcoholic 
solution. 

Nitro-glycerin is given in tablets, or in the form 
of the alcoholic solution, strength i per cent. This 
preparation should be constantly renewed, as it decom- 
poses with age. In the case of an unconscious patient it 
may be dropped on the back of the tongue. 

Dose, TTt ss.-ii. ; iii ; in a little glycerin (iU x. = gtt. 
xxv.). (0.03-0.18 gm.) 

Acidum Carbolicum, Carbolic Acid, Phenol. 

Carbolic acid is a product of the distillation of coal tar. 
It may also be obtained by the distillation of other 



THE CARBON COMPOUNDS. 97 

organic substances, and, finally, may be made artificially 
— synthetic carbolic acid. Crude carbolic is an imper- 
fectly purified article, the result of two distillations. 
It is a dark-reddish liquid, useful as a disinfectant, and 
cheap. Further distillations produce the pure acid, 
which is colorless, crystallizes in needles, and, if abso- 
lutely pure, does not absorb water from the air. 

Usually, however, a trace of water is present, by which 
it becomes deliquescent, or, with the addition of a minute 
quantity of water, the melted crystals will remain as an 
oily liquid, and not re-crystallize. It sometimes acquires 
a reddish color on exposure, said to be due to minute 
quantities of metal, probably copper, contained in traces 
of the tar products present. 

Carbolic dissolves in water, 15 parts of water being 
given by the Dispensatory as the dissolving point at 59 
F. The standard solution of ward use is made with 20 
parts. It is not always well understood among nurses 
that carbolic will dissolve in 20 parts of cold water. Hot 
water, of course, makes the mixing easier. The solution 
should be perfectly clear. If it is cloudy or contains 
globules it is not thoroughly dissolved, and needs shak- 
ing. Carbolic is freely soluble in glycerin, alcohol, and 
ether. 



Physiological Effects. 

Carbolic acid applied locally is antiseptic, irritant, 
and anaesthetic. In concentrated form it is a severe 
caustic. The vapor, internally, is stimulant and disin- 
fectant. Taken into the stomach, the acid arrests fer- 
mentative changes, and in large doses is a powerful 
irritant and narcotic poison, acting on the respiratory 
and vasomotor centres, which it quickly paralyzes. It 
is rapidly absorbed by the unbroken skin, the subcuta- 
neous tissues, the mucous surfaces, wounds, the respira- 
tory passages, and the stomach, and is excreted by the 
urine, to which it gives a dark, smoky, or greenish color ; 
also by the saliva, which is increased in quantity. 
7 



98 MATERIA MEDICA FOR NURSES. 

Carbolic acid is a deodorizer and disinfectant as well 
as an antiseptic. It is very destructive to low forms of life 
if used in sufficient strength, but in solutions of a strength 
which may be safely used externally, as in the dressing of 
wounds, or internally, as for vaginal douches, it only pre- 
vents the development of germs, and does not kill their 
spores. 

Symptoms of Poisoning. 

The first signs of poisoning from the use, either ex- 
ternal or internal, of carbolic acid, are : giddiness, tension 
of the head, and, usually, the dark color of the urine. 
More serious evidences of danger are : contracted pupils ; 
pallor ; embarrassed breathing ; a small, slow, feeble pulse ; 
ringing or singing in the ears ; and sudden vertigo. 

When swallowed in poisonous doses there is at once a 
hot burning sensation from mouth to stomach, and the 
symptoms come on immediately. The lips and lining of 
the mouth are white and hardened ; there is nausea, with 
violent pain and vomiting of frothy mucus ; the lips, ears, 
and eyelids are livid ; the pupils contracted and insensible 
to light. The skin is cold and covered with clammy per- 
spiration ; the pulse very feeble and almost always rapid, 
— 1 20— though it has been known to fall to 40 or 50 a 
minute ; the respirations are rapid, irregular, and diffi- 
cult, sometimes stertorous, sometimes gasping, and the 
breath has the odor of the acid. Insensibility, coma, and 
collapse follow quickly in succession, and death may 
occur within a few minutes from paralysis of the respir- 
ation, or, if a very large amount has been taken, from 
paralysis of the heart. The average time of death is be- 
tween one and ten hours, and the fatal dose may range 
from 3 i. to f ss. (4.-16. gm.) 

Treatment of Poisoning. 

In the treatment of this poison emetics are not always 
of use, owing to a paralyzed condition of the stomach, 



THE CARBON COMPOUNDS. 99 

and the stomach-pump should be used. The chemical 
antidotes are sulphate of magnesia or of soda, or syrup 
of lime, and they should be freely given ( 3 iii. of the 
sulphates have been given) as long as the patient can 
swallow, or until there is improvement. Lime water and 
milk in equal parts may be given, and vegetable demul- 
cents — as flaxseed tea, but no oils or glycerin, as they 
dissolve the acid and aid its absorption. Atropine is a 
physiological antagonist, maintaining respiration ; and 
cardiac stimulants may be required, given hypodermi- 
cally. 

Carbolic acid is in general use as an antiseptic and 
disinfectant, though the manner of its employment has 
been greatly modified and changed in some respects from 
that of former years. For the practical work of the 
nurse in cleaning and disinfecting it stands high, and is 
used in a strength of 1 in 20 or 1 in 40. Articles to be 
disinfected, viz.: soiled clothing, sputum cups, etc , must 
soak in it for varying lengths of time, according to the 
nature of the case. 

Carbolic acid may be used for clothing, as it does not 
stain In the sick-room its strong odor makes it un- 
pleasant to many persons, and this odor may be covered 
by using oil of peppermint or cinnamon. 

Dose, "ni i.-iii. (tT[ x. = gtt. xviii.), in glycerin or 
simple syrup — well diluted. 

There is a large and constantly increasing group of 
compounds allied to carbolic acid, called cresols. They 
are derived from coal tar, and possess strong antiseptic 
and germicidal powers. As a rule, they are less poison- 
ous than carbolic acid. Among them may be mentioned 
creolin, lysol, saprol, sozal, chlorphenol, pheno-salyl, 
aseptol, etc. The well-known Dobell's solution contains 
carbolic acid, soda bicarbonate, and glycerin. 

Creosotum (Creasote). 

Creasote is produced by the distillation of wood tar, 
and is a very complex substance, containing many hydro- 



IOO MATERIA MEDIC A FOR NURSES. 

carbons, some of which are closely related to carbolic 
acid. Creosote is not as poisonous as carbolic acid, nor 
so active as a germicide and antiseptic, but many of its 
physiological properties are similar, and its value medic- 
inally is about the same, though it is oftener used. 

It is a stimulant, expectorant, and gastric seda- 
tive. In the stomach it checks fermentation, yet does 
not interfere with digestion. The vapor is disinfectant 
and deodorant. When inhaled it is stimulant, and 
when ordered in this way it is convenient to use a small 
cone, which may be easily improvised. 

Only a few cases of poisoning are recorded. The 
symptoms and treatment are like those of carbolic acid. 

Dose, Til i.-iii. (t\[ x. = gtt. xx.). (0.06-0.2 gm.) 

Aqua Creasoti. 
Creasote Water. 

Strength, 1 per cent. Dose, 3 i.-iv. (4-16. gm.) 
Guaiacolum (Guaiacol). 

Obtained by distilling beechwood-tar creosote, and 
used in the treatment of pulmonary phthisis, etc. 
Derivatives of guaiacol : 

Bonzosal. Guaiacol Carbonate. 
Styracol. " Salicylate. 

Acidum Salicylicum (Salicylic Acid). 

Salicylic acid is prepared synthetically by treating a 
solution of carbolic acid in caustic soda with carbonic 
acid, at a moderate heat. It is also found in nature in 
oil of wintergreen, in sweet birch, and in the bark of 
several varieties of willow. A dull white powder, readily 
soluble in alcohol and glycerin, but almost insoluble in 
cold water. In hot water it is more readily dissolved, 
and borax and boric acid assist the solvent action. 



THE CARBON COMPOUNDS. 10 1 

Physiological Actions. 

Salicylic acid is an antiseptic and disinfectant. It 
is a diaphoretic and antipyretic in fever, but does 
not lower the temperature in health. It is not much 
used in this way, as other antipyretics are more lasting 
in influence and less depressing than salicylic acid. 

After an antipyretic dose there is slight temporary 
stimulation of the heart ; the face and eyes are suffused 
and there is a feeling of warmth, followed by perspira- 
tion. These effects are visible in ten or fifteen minutes, 
and following them there is a reduction of the strength 
of the heart. 

Salicylic acid has a stimulant and disinfectant action 
on the kidneys and urinary apparatus, and increases the 
acidity of the urine. In some cases it irritates the 
kidneys and causes hsematuria or albuminuria. 

In small doses it stimulates digestion, the heart, and 
respiration, but in large doses it depresses the two latter, 
lowers arterial tension, and causes nausea and vomiting. 

Incidental Effects. 

In giving salicylic acid the first evidences of over-dosing 
which are to be looked for, are buzzing and roaring 
in the ear, and fulness of the head. Increased doses 
bring severe headache, perspiration, deafness, and various 
disturbances of vision ; and, if still continued, these 
symptoms are all intensified. The respirations become 
deeper and are labored, rapid, and irregular — sometimes 
the most violent respiratory efforts being made to over- 
come the dyspnoea ; the pulse is slow and weak, and 
there is great restlessness, with a delirium characterized 
by hallucinations of vision, and which is sometimes 
cheerful, sometimes melancholy, and sometimes wildly 
maniacal. The urine may be dark olive-green, and 
involuntary evacuations of the bowels may take place. 

The depression of the circulatory system causes a re- 
laxed state of the skin, and bed-sores are liable to appear 



\02 MATERIA MEDIC A EOR NURSES. 

rapidly. Eruptions of the skin, somewhat resembling 
that of urticaria, may appear even after medicinal doses. 

Salicylic acid is not considered an active poison to 
man. Cases of death from its use have been recorded, 
but they are not all well verified, and poisonous symptoms 
almost always disappear, on the withdrawal of the drug, 
in a few days, or a week. 

Salicylic acid is transformed in the blood into sali- 
cylate of sodium, and is slowly excreted by the urine, 
perspiration, saliva, bile, and mucous secretions. 

Dose, gr. v.- 3 i., moderately diluted. (0.3-4. gm.) 

Sodii Salicylas. 
Sodium Salicylate. 

Made by the action of salicylic acid on carbonate of 
sodium. It is readily soluble in water ; has the same 
physiological actions as salicylic acid, and is less irri- 
tating. It has no antiseptic qualities in external use. It 
is considered a specific in rheumatism, and in giving a 
course of it the same incidental symptoms mentioned 
under salicylic acid are to be looked for. 

Dose, gr. v.- 3 i., moderately diluted. (03.-4. gm.) 

Salol. 

Phenyl Salicylate. 

A preparation composed of two thirds salicylic and 
one third carbolic acids. It is insoluble in water and is 
given in compressed tablets. 

Salol is antiseptic and antipyretic ; sedative to 
the brain and spinal cord, and with some power as an 
analgesic. It is an active diaphoretic, and though 
in some cases it has a somewhat depressing effect, yet its 
action is usually not marked by as much exhaustion as 
that of many of the new antipyretics, and when the 
temperature rises after being reduced by salol, it does so 
without chill or chilly feelings. Its physiological effects 
and medicinal uses are in general very like those of 
salicylic acid. It is not considered poisonous, and is, 
like iodoform, used as a topical application. 

Dose, gr. v.-xv. (0.3-1. gm.) 



THE CARBON COMPOUNDS. 103 

OUuT'caultheri*. \ See ° r S anic Materia Medica ' 
Thiersch Powder. 

A combination of salicylic and boric acids, usually 
ordered in the proportion of 1 ss. of the latter to 3 ss. 
of the former. Added to one quart of water it forms an 
antiseptic solution, of moderate power, which is not 
irritating or poisonous when freely used. The propor- 
tions of a Thiersch powder are not invariable, as Prof. 
Thiersch does not confine himself to one formula. 1 

Sodio-Theobromine Salicylate. 
Diuretin. 

Diuretin is made from theobromine, an alkaloid ob- 
tained from the seeds of Theobroma Cacao, the chocolate 
tree of South America, and sodium salicylate. It is a 
white powder, soluble in half its weight of warm water. 
As the theobromine separates from it on exposure to 
the air, it should not be given as powder, but as freshly 
prepared aqueous solution. 

Physiological Actions. 

It is a reliable diuretic, increasing the amount of 
urine, and the solids excreted by the urine. Its influence 
over the amount of albumin is not constant. However, 
in chronic nephritis the amount of albumin is generally 
diminished. In dropsy, with the increase of urine, there 
is disappearance or marked improvement of the oedema. 
Occasionally a profuse diarrhoea is apparently produced 
by the remedy, and assists in this removal of the 
transudation. 

It is believed that the drug has a marked influence 
on the heart. It strengthens and .regulates it, is not 
depressing, and produces no functional disturbance. It 
does not appear that it causes any irritation either of the 
stomach or kidneys. Its diuretic action depends on a 
direct influence on the renal epithelium. 

Dose for an adult, gr. xv.-xx. (1.-1.3 gm.) 

1 Charles Rice, Ph.D. 



104 MATERIA MEDIC A FOR NURSES. 

Naphthalinum (Naphtalin). 

A coal-tar derivative with the taste and odor of tar ; in- 
soluble in water, soluble in ether, hot alcohol, and benzol. 

It is antiseptic and destructive to low forms of life. 
Internally it is a stimulant expectorant, and acts as 
a disinfectant to the alimentary canal. The latter 
action is a local one, as it is not readily absorbed into 
the system, but is mostly carried away by the faeces ; 
that part of it taken up by the blood being excreted by 
the urine partly unchanged and partly as naphtol. Ex- 
ternally it is used as an antiseptic. 
Naphtol. 

Derived from naphtalin ; soluble in alcohol, ether, 
chloroform, oil, and vaseline. It is more easily absorbed 
than naphtalin, and causes vomiting, haematuria, con- 
vulsions, and unconsciousness. In medicinal doses it is 
an intestinal disinfectant, in doses of from gr. iii.-iv. 
(0.20-0.25 gm.). It is also used as a local application, 
dissolved in alcohol, in from 1 to 50 ^. 

Allied to naphtol are : 
Microcidin. Alumnol. 

Benzonaphtol. Hydronaphtol. 
Betol. Asaprol. 

Chinolin. 

Chinolm is a derivative of cinchona bark, from which 
it is named, and is also found in coal-tar oil. It is 
made synthetically by the action of glycerin on nitro- 
benzol and aniline. It is a colorless, oily liquid, and on 
exposure to the air turns dark. Like an alkaloid, it com- 
bines with acids to form salts. It is antiseptic. 

The taste and odor are very disagreeable. It resembles 
quinine somewhat in its antipyretic action. After a full 
dose there is a short preliminary stage of excitement, 
with increased pulse and a feeling of warmth, followed 
by perspiration, fall of temperature, slow and weak pulse, 
and lessened respirations. In large doses it diminishes 
reflex action and causes dyspnoea, paralysis, and collapse. 
Only one salt, the tartrate, is used medicinally. 



THE CARBON COMPOUNDS. 105 

Chinolin Tartras. 

Dose, gr. v.-xx., may be given with peppermint water. 

Chinolin is not in general use, and is here placed be- 
fore some of the more practically important antipyretics 
in an introductory way. Many of these medicines, 
which are synthetically prepared in laboratories, are the 
results of experiments made in the attempt to produce 
an imitation of quinine, and different ones are derived 
from chinolin. (0.3-1.3 gm.) 

Antipyrin. 

Antipyrin is a coal-tar derivative, being prepared from 
chinolin. It is an alkaloidal body, combining with acids 
to form salts. A whitish, crystalline powder of slightly 
bitter taste, soluble in water in a proportion of ten parts 
to six parts of water. 

Physiological Actions. 

When first introduced it was a proprietary medicine 
and was known principally as an antipyretic. With 
further use and investigation other therapeutic qualities 
have been manifested. 

It is a general nerve sedative and anodyne, having 
a considerable degree of power in the relief of pain in 
various conditions of nervous origin. It is slightly 
antiseptic and disinfectant, diaphoretic, and has 
some diuretic action. It is also credited with being to 
some extent a haemostatic. Antipyrin does not lower 
the normal temperature, but in fever its action is very 
marked. There is a short period of stimulation, with 
flushing of the face, a feeling of heat, and increased 
action of the heart. In about half an hour or more per- 
spiration breaks out and usually becomes very profuse. 
The pulse is then slowed, but not always weakened. 
The skin is cool ; there may be chilly feelings, and the 
temperature falls from one to several degrees, according 
to the amount taken, and remains down for a length of 
time, also proportioned to the dose — usually two or three 
hours, and often longer. 



106 MATERIA MEDIC A FOR NURSES. 

There results very often — especially in subjects weak- 
ened by a long illness — a decided state of depression, 
sometimes so marked as to be alarming, and the pulse, 
though not always weakened, is in some cases seriously 
so. The use of antipyrin in acute illness often causes 
nausea and vomiting, though it is not a gastric irritant 
in any special sense, but in small doses tonic, increasing 
the appetite. Symptoms which indicate danger in giving 
antipyrin are cyanosis, muscular weakness, disturbed 
and rapid respirations, weakened irregular pulse, 
dyspnoea, and sensations of heat over the body. Col- 
lapse may result from its use, and death in one instance 
followed the administration of fifty odd grains. An 
eruption of the skin frequently occurs, with some con- 
stitutional disturbance and considerable suffering and 
annoyance from the itching, which is severe. It lasts for 
several days, and in the majority of cases resembles the 
measles rash ; but sometimes appears as a general and 
intense erythema, with swelling of the face, especially 
about the eyes, burning sensations, and rise of tempera- 
ture. Antipyrin has been given hypodermically, but is 
irritant and liable to cause abscesses. If so given it 
should be injected deeply into the gluteal muscular 
tissue. 

Dose, gr. v.-xx., diluted moderately. It may be given 
in a little wine, or iced brandy and water ; and to chil- 
dren, in syrup. (0.3-1.3 gm.) 

Acetanilidum (Acetanilid) 
Antifebrin. 

A neutral substance derived from anilin by the action 
of glacial acetic acid. A colorless crystalline powder of 
slightly burning taste, soluble in alcohol, but not readily 
so in water. 

Its medicinal qualities are very similar to those of 
antipyrin, it being antipyretic, analgesic, and a ner- 
vous sedative. It has some differences of action. It 
diminishes the irritability of sensory nerves, lessens the 
reflex action of the spinal cord, raises arterial tension to 
some extent, and slows the heart correspondingly. The 



THE CARBON COMPOUNDS. \OJ 

reduction of temperature by acetanilid takes place rather 
more slowly than that caused by antipyrin — sometimes 
twice as much time being required. 

The effects last longer — six or seven hours — and the 
fall is sometimes, though not always, accompanied by 
perspiration rather less profuse than that produced by 
antipyrin. The lowering of the temperature is not sup- 
posed to depend on this diaphoresis, as experiments 
show that one sometimes follows without the other. 

The antipyretic action of acetanilid is occasionally 
followed by cyanosis, and in rare cases by collapse, 
though it is usually considered less apt than antipyrin to 
produce severe depression, and in the majority of cases 
its use leaves no ill after-effects and does not nauseate. 
It has diuretic action and is a cerebral stimulant, while 
antipyrin depresses the brain. A poisonous dose de- 
stroys the ozonizing function of the blood. 

Incide?ital effects noticed sometimes after its use are 
deafness, ringing in the ears, dilatation of the pupils, and 
an eruption similar to that caused by antipyrin. 

Dose, gr. v.-xv. It may be given in dilute alcoholic 
solution, and, like many remedies to-day, is put up in 
compressed tablets. (0.3-1. gm.) 

Allied to acetanilid are : 

Benzanilid. Exodyne. 
Antikamnia. Phenolid. 
Antinervin. 

Resorcin. 

Resorcin is obtained from galbanum, a resin, by 
the action of alkalies. It is also made from carbolic 
acid, thus belonging to the phenol group or derivatives 
of coal tar. It occurs as white crystals with an odor 
resembling carbolic acid, and is soluble in water, and 
also in alcohol. It is antiseptic and disinfectant, 
inferior, however, in these respects to carbolic acid. 
It has considerable antipyretic action, in large doses, 
causing free diaphoresis with reduction of the pulse 



108 MATERIA MEDIC A FOR NURSES. 

and temperature. The pulse may, within an hour, be 
slowed by as much as one third its former number of 
beats, and the temperature fall three or four degrees, 
to remain down for from two to four hours, when it 
rises again rapidly. While rising there may be chilly 
feelings, or a distinct chill. 

Doses which produce these results, viz., gr. xxx.-lx., 
cause also, as preliminary symptoms, dizziness, ringing 
in the ears, frontal headache, trembling, and quickened 
respirations. With the breaking out of perspiration 
these disturbances die away. No fatal case of poisoning 
is known. In one case, where 120 grains were taken, 
giddiness, and a feeling as of the pricking of pins came 
on immediately. Unconsciousness followed, with sub- 
normal temperature and thready pulse. 

The chief action of resorcin is upon the nerve centres, 
and it has been shown experimentally that very large 
doses paralyze the heart. 

Dose, gr. ii.-v. (0.1-0.35 gm.) 

It is used in an ointment, strength from 5 to 30 per 
cent. 

Pheno-Resorcin. 

A mixture of carbolic acid and resorcin, in the pro- 
portion of two thirds of the former and one third of the 
latter. Its qualities have not been thoroughly tested. 

Phenacetine. 

A preparation belonging to the phenol group ; a 
decided antipyretic, being also antiseptic, sedative, 

and analgesic. After large doses profuse sweating is 
the first result, appearing in from thirty to fifty minutes, 
and in one or two hours the temperature begins to fall, 
reaching its lowest point in about four hours. The 
reduction is quite marked, averaging about 3 , while a 
fall of 5 or 6° has been known. Some depression may 
follow — not severe enough usually to be alarming — with 



THE CARBON COMPOUNDS. 1CX) 

weak and chilly feelings and weakened pulse. The rise 
of temperature is more gradual than the fall. In com- 
parison with the activity of other antipyretics, ten grains 
of phenacetine are said to equal fifteen grains of antipy- 
rin or quinine, and thirty grains of salicylate of soda, 
and to be equal in power with antifebrin, though less 
rapid in action and more enduring in its effect. 

An eruption of the skin sometimes occurs in anaemic 
patients. 

Phenacetine is almost insoluble in water, and is given 
dry on the tongue, or in compressed tablets, or capsules. 

Dose, gr. iii.-x. (0.2-0.65 gm.) 

Allied to phenacetine are : 

Iodophenine. Hydracetin. 
Methacetin. Phenocoll Hydrochloride. 

Exalgine. 

A preparation introduced by French physicians, de- 
rived from acetanilid. It has analgesic power, and the 
name was given with reference to this quality, and does 
not describe its chemical constitution, as do many of the 
names of new remedies. It is hypnotic and anodyne, 
and comparatively free from ill after-effects. 

Its action in the relief of pain is rapid. In some cases, 
dizziness, trembling, weakness of the knees, and loss of 
muscular power in the eyelids have appeared almost im- 
mediately after its administration, passing off in a short 
time. 

It is given dry on the tongue, in powder or in tablets. 

Dose, gr. v.-x. (0.3-0.65 gm.) 

Pyridine. 

Pyridine is found in nature as one of the principles of 
tobacco-juice, and is imitated in chemistry, and derived 
from chinolin. It is a volatile liquid with strong aro- 



IIO MATERIA MEDIC A FOR NURSES. 

matic odor. It gives off, at ordinary temperatures, a 
vapor which is used medicinally, having a stimulant 
effect on the respirations and on the spinal cord. On 
the heart it has an influence resembling that of digitalis, 
increasing the strength of the systole. 
Dose, TTj, v.-xx. (0.3-1.3 gm.) 

Saccharin. 

Saccharin is a substance produced by a very complicated 
chemical process from a coal-tar product called toluene. 
It is the sweetest of known substances, being between 
two hundred and three hundred times sweeter than 
sugar, but in chemical constitution it is an acid. 

It is not a food, like sugar, nor a medicine, as it has 
no special effect on the system. It may be used instead 
of sugar in diseases where sugar is forbidden, and may 
also be combined with quinine, the bitter taste of TV hich 
it entirely disguises. 

It has antiseptic power. 

Oleic Acid. 

A fluid fatty acid made from olein, the fluid principle 
of oils and fats, by the action of heated steam. It is 
used in the preparation of medicinal ointments called 
oleates, two of which are officinal, the oleate of veratrum 
viride, strength 2 per cent., and the oleate of mercury, 
-strength 10 per cent. 

The oleate of zinc is also used. 

Petrolatum. 

Vaseline. 

Vaseline is a semi-solid substance obtained from petro- 
leum by distillation and purification, and is used alone 
as an emollient, and also as the basis of various oint- 
ments. 



THE CARBON COMPOUNDS. Ill 

Glycerinum (Glycerin). 
Propenyl Alcohol. 

Glycerin is obtained by the reaction of fats and 
fixed oils with watery alkaline fluids. Chemically it is 
classed with the alcohols. It is always set free in the 
process of soap making as a waste product, and so made 
is purified and sold, though the larger part of the 
glycerin in commerce is manufactured directly by the 
decomposition of fats by heated steam. 

Glycerin absorbs water from the air and mixes with 
water in all proportions. If pure it cannot become rancid. 

Applied externally it is unirritating to the sound skin, 
but painful if there are any abrasions. 

It is slightly stimulant and antiseptic, and tends to 
make the skin dry and brittle. It is readily absorbed 
when applied externally. 

Internally it has no special effect on the stomach, but 
is supposed to have some nutritive power. It is produced 
normally in the intestines during the digestion of oils and 
fats. If administered in free doses it has a laxative 
action, and for this purpose is given alone, or in com- 
bination with castor oil, in doses of | ss.-i. 

The laxative action is very notable when glycerin is 
administered as an enema ; a small amount— 3 ss.— § ii. 
— acts quickly and satisfactorily. 

Glycerin suppositories are also, in most instances, very 
efficacious. 

Preparations. 

Glcyeritum Acidi Carbolici. 
Glycerite of Carbolic Acid. 

Contains 20 parts of carbolic acid to 80 of glycerin. 
Glyceritum Acidi Tannici. 
Glycerite of Tannic Acid. 

The same strength as the above. 
Glyceritum Boroglycerini. 
Glycerite of Boroglycerin. 

Boric acid 3 parts to 7 of glycerin. 



PART II. 

THE ORGANIC MATERIA MEDICA. 

THE VEGETABLE KINGDOM. 



Arranged under Botanical Divisions or Natural Orders. 



Nat. Ord. Ranunculacea. 
Aconitum (Aconite). 

Monk's-hood, Wolfsbane. 

Aconite is a tall perennial plant bearing a spike of 
blue flowers ; found native in Europe, and cultivated in 
the United States. The officinal portion is the root, 
which is from 3 to 4 inches long, about f inch in 
diameter at the base, and tapers to a fine point. It is 
brown in color, externally, and has been mistaken for 
horse-radish, but the latter is whitish, does not taper 
gradually but has almost the same diameter for several 
inches, and has a strong odor when scraped, which 
aconite root has not. 

There are several varieties of the plant, all more or less 
poisonous. 

Physiological Actions. 

Aconite applied locally to the skin or mucous mem- 
brane acts on the terminations first of the sensory and 
8 113 



114 MATERIA MEDICA FOR NURSES. 

next of the motor nerves, as a depressant or sedative, 
and causes tingling followed by numbness and insensi- 
bility. 

Taken internally aconite is sedative to the heart and 
respirations ; is diuretic and diaphoretic, and reduces 
temperature. It has no effect on the brain. Me- 
dicinal doses, given close together, reduce the frequency, 
force, and- tension of the pulse, produce a gentle per- 
spiration, and increase the amount of urine. Respiration 
becomes slower and deeper ; the temperature falls. The 
tendency of the pulse under the influence of aconite is 
to become small, compressible, and weak. 

Larger doses, or a single full medicinal dose, produce a 
tingling feeling, usually first noticeable in the lips or ex- 
tremities : or, if the impression be decided, the tingling 
may be felt over the whole body. 

There may be also a raw, irritable, or constricted feel- 
in the throat, and difficulty in swallowing, caused by 
anaemia of the throat. There is muscular weakness ; 
giddiness and disorders of vision may be produced, 
especially if any exertion is made ; the respirations are 
diminished, and the pulse may fall to 30 or 40 a minute. 

The first effects of medicinal doses are usually shown 
in half an hour, and the symptoms mentioned will pass off 
in three or four hours. After poisonous doses, if large, 
death may occur immediately from instant paralysis of 
the heart-muscles ; or the symptoms may come on in a 
few moments and death occur soon after, the average 
time being between three and four hours. 

Symptoms of Poisoning. 

The first symptom of poisoning is the characteristic 
tingling, which is diagnostic of every variety and prep- 
aration of aconite. 

The pulse fails rapidly, becoming weak, irregular, in- 
termittent, and slow ; the respirations are shallow, weak, 
and sighing, irregular and slow. There is anaesthesia of 
the surface and great muscular weakness ; the tongue 
and breath are cold ; the skin covered with a cold sweat. 



THE VEGETABLE KINGDOM. II 5 

The face has an anxious look and is sunken and livid. 
The eyes are glaring, the eyeballs protruding ; the pupils 
are generally dilated. The voice is suppressed. There 
may be vomiting, although it does not always occur. 
The mind usually remains clear, but there are sometimes 
convulsions, and in these cases stupor and unconscious- 
ness may be present. In the latter stages of collapse the 
special senses may be lost, especially the sight. 

Treatment of Poisoning. 

The first thing necessary is to empty the stomach and 
wash it out with the stomach-pump. Hot and concen- 
trated alcoholic stimulants are given ; external heat ap- 
plied ; the patient's head lowered beneath the line of his 
feet by taking out the pillows and elevating the foot of 
the bed ; and absolute quiet and rest maintained. 
Artificial respiration may be practised, and cardiac 
stimulants given hypodermically. 

Atropine is a physiological antagonist, stimulating 
respiration, and ammonia has the same effect. Digitalis 
counteracts the depression of the heart, but acts slowly, 
while aconite is exceedingly rapid in action. 

Precautions. 

The pulse should always be taken before giving a dose 
of aconite, and respirations and temperature watched. 
Any possibility of cold air or draughts must be guarded 
against, the skin being relaxed, and no exertion on the 
part of the patient — such as sitting up in bed — allowed. 

Preparations of Aconite. 



Extractum Aconiti. 

Made from the leaves. Dose, gr. J-f . (0.015-0.045 gm.) 
Extractum Aconiti Fluidum. 

Dose, TT[ i.-ii. (fT|, x. = gtt. xxv.). (0.06-0.13 g m -) 



Il6 MATERIA MEDIC A EOR NURSES. 

Tinctura Aconiti. 

Made from the root. Strength, 40 $, or J vss. in Oj. 
Dose, TFX i.-iv., in water. (0.06-0.25 gm.) 
Fleming's Tincture of Aconite. 

Made from the root. Strength, 79 $, or | xss. in Oj. 
Dose, TTl ss.-ii., in water. (0.03-0.13 gm.) 

Aconitina. 

An alkaloid or active principle obtained from aconite. 

Dose, gr. ^—fa- (0.0003-0.0013 gm). 
Linimentum Aconiti. 

For external use ; strength, 2 </ . St. Jacob's oil, a 
quack medicine, contains aconite. 

Pulsatilla (Pasque-flower). 

The herb of two varieties of anemone furnishes an 
acrid oil, which is reducible into anemonic acid, and a 
volatile principle called anemonin. This is the active 
ingredient of Pulsatilla, and gives the drug its character- 
istics. It is like aconite in its physiological effects. 

Dose of the tincture, Til i.-x. (0.06-0.65 g m -) Dose 
of anemonin, gr. 3^— ii. (0.06-0.13 gm.) 

Staphisagria (Stavesacre). 

The dried ripe seeds of Delphinium Staphisagria. 
They possess four alkaloids, one of which, delphinine, 
is closely allied to aconitine, resembling it strongly in 
action. It is even more depressing. The only use of 
staphisagria is as a parasiticide. The preparation for 
this purpose is called delphine. 

Podophyllum (May Apple ; Mandrake). 

The dried rhizome * and rootlets of the May apple, a 
perennial herb of the Northern and Middle United 
States. An alkaloid, berberine, and two resins, are the 
active principles. 

1 Root stock. 



THE VEGETABLE KINGDOM. \lj 

Physiological Actions. 

Podophyllum is an active cathartic with chola- 
gogue properties. Its actions are shown not only when 
taken internally, but also when applied to a broken sur- 
face or given hypodermically. It has a bitter acrid taste, 
and causes slight salivation, irritation of the stomach, 
nausea, and griping pains. In large doses it causes 
severe colic. The purgative action is very slow, requir- 
ing ten hours or more, and is due to stimulation of the 
intestinal glands and of the muscular coats of the in- 
testine ; also to a stimulant action on the liver, with a 
decided increase in the flow of bile. 

In large quantities it may cause poisoning. Cases of 
poisoning in children have happened, with vomiting, 
purging, epileptiform convulsions, coma, and collapse. 

Preparations. 

Extractum Podophylli. 

Dose, gr. i.-iii. (0.06-0.2 gm.) 

Resina Podophylli. 

Dose, as a laxative, gr. T V (0.005 g m -) 
As a purgative, gr. \-\. (0.01-0.015 gm.) 

Extractum Podophylli Fl. 

Dose, HI v.-xv. (TTL x. = gtt. xii.). (0.3-1. gm.) 
Podophyllum used externally is irritant, and may 
inflame the eyes if carelessly handled. 

Cimicifuga (Black Snakeroot). 

The dried rhizome and rootlets of Cimicifuga race- 
mosa, an indigenous plant, containing a volatile oil, two 
resins, and tannin. 

Cimicifuga has antispasmodic action. In moderate 
doses it has been used as a stomachic and cardiac 
tonic, and it increases somewhat the action of the skin 
and kidneys. In large doses it slows the heart, and'raises 
blood-pressure, acting like digitalis, and in excessive 
doses it produces giddiness, severe headache, and pros- 



Il8 MATERIA MEDIC A FOR NURSES. 

tration. No cases of poisoning are known. The prep- 
arations should not be kept long, as they spoil with age. 

Preparations. 

Extractum Cimicifugae Fl. 

Dose, TTi xx- 3 i. (nx x. = gtt. xii.). (0.3-1. gm.) 
Tinctura Cimicifugae. 

Dose, 3 i.-ii. (4.-8. gm.) 

Adonis Vernalis. 

The root of Adonis vernalis contains a glucoside 
named adonidin. It is allied in action to digitoxin, one 
of the principles of digitalis, but is more powerful and 
irritating to the digestive organs. 

Physiological Actions. 

Adonidin stimulates the heart and vaso-motor cen- 
tres, acting more promptly than digitalis. It is not cumu- 
lative in tendency. It has no special power as a diuretic, 
though there may be some slight action resulting from 
the effect upon circulation in the kidneys. 

In overdoses adonidin produces vomiting and diar- 
rhoea. 

Preparations. 

Adonidin. 

Dose, gr. J. (0.02 gm.) 
Infusion of Adonis Vernalis. 

Strength, 3 ss.-ii. of the root to § vi. 

Hydrastis (Golden Seal). 

The roots and root stocks of Hydrastis Canadensis yield 
the alkaloids verberine, xanthopuccine, and hydrastine, 
of which the latter is the active principle. 

Physiological Actions. 

Hydrastis is an astringent bitter. It stimulates the 
gastro-intestinal tract, creates appetite, and promotes the 



THE VEGETABLE KINGDOM. 119 

functions of the liver. It is also an anti-periodic. It is 
ecbolic, causing uterine contractions. Applied locally 
to mucous membranes it is tonic. 

In poisonous doses it has caused salivation, vomiting, 
muscular tremblings, loss of voluntary movement, rise of 
temperature, feeble, rapid pulse, convulsions, and death 
from failure of the respirations. 

Preparations. 

Tinctura Hydrastis. 
Tincture of Hydrastis. 

Dose, 3 i. 
Extractum Hydrastis Fluidum. 
Fluid Extract of Hydrastis. 

Dose, 3 ss. 
Hydrastininae Hydrochloras. 
Hydrastinine Hydrochlorate. 

A synthetic alkaloid obtained by oxidizing hydrastine. 
It is an oxytocic and muscular stimulant. In over- 
doses a depressant to the whole motor tract. 

Dose, gr. \-\. (0.03-0.06 gm.) 

Nat. Ord. Menispermacea. 
Calumba. 

The root of Jateorhiza palmata, of Eastern Africa, 
contains an alkaloid, berberine ; a bitter neutral principle, 
colombin ; and colombic acid. It contains no tannin, 
and may be given with iron. 

Calumba is a bitter tonic and stomachic, stimulating 
the flow of saliva, the glands and blood-vessels of the 
stomach, and also the gastric nerves, causing a sensation 
of hunger. Calumba, like bitters in general, has some 
power to overcome fermentation or decomposition in the 
stomach and intestines ; promotes peristalsis ; (bitters 
containing tannin have not this property) removes flatu- 
lence and tends to regulate the evacuation of the bowels. 

Bitters if given in excess or for a long time, irritate 



120 MATERIA MEDIC A FOR NURSES. 

the stomach and bring on indigestion. Calumba is one 
of the least irritating of this class of medicines. 

Like all bitter stomachics it must be given well diluted, 
and about half an hour before meals. 
Tinctura Calumbae. 

Strength, i to 9. Dose, 3 i.-ii. (4-8. gm.) 
Extractum Calumbae Fluidum. 

Dose, TTi xv- 3 ss. (TTl x. = gtt. xiv.). (1.-2. gm.) 

Picrotoxinum (Picrotoxin). 

The fruit (called fish berries) of Anamirta paniculata, 
an Asiatic plant, yields an active principle, picrotoxin, a 
bitter neutral substance. 

It is an active excitant of the brain and spinal cord ; 
stimulates secretions, especially of the intestines ; causes 
nausea and vomiting, and slows the heart and respira- 
tions. In overdoses it produces muscular twitchings, 
stupor, delirium, convulsions, and coma ; and may cause 
death by paralysis of the heart. 

The temperature is slightly raised by picrotoxin. 

It has been used externally in an ointment, and con- 
vulsions and death have followed its use in this way. 

Preparations. 

Picrotoxin. 

Dose, gr. fa-fa, in pill. (0.0016-0.003 gm.) 

JVat. Ord. Papaveracecz. 
Opium. 

Opium is the juice of the unripe capsules of the 
Papaver somniferum or white poppy, thickened by evap- 
oration (inspissated), and is obtained by incising the 
capsules with a small sharp knife, when the juice flows 
forth, and hardens into a semi-solid mass. It is produced 
chiefly in Turkey, Asia Minor, Persia, and India. 

That used in the United States is almost all brought 
from Asia Minor and called Smyrna or Turkey opium. 
Official dried opium should contain from 13 to 15 <? of 
morphine. 



THE VEGETABLE KINGDOM. 121 

When dried and powdered, opium is yellow brown in 
color, and dissolves in water, alcohol, and dilute acids. 

Opium is an exceedingly complex substance, contain- 
ing the alkaloids morphine, codeine, narceine, narcotine, 
thebaine, papaverine, porphyroxine, cryptopine, meco- 
nine, opianine, and paramorphine ; meconic, thebolactic, 
and sulphuric acids ; fixed oils, odorous principles, ex- 
tractives, gum, resin, salts, glucose, and other unim- 
portant substances, with about 16 per cent, of water. 

Physiological Actions. 

Opium is generally considered to be anodyne and 
anaesthetic when applied to the unbroken skin, yet some 
authorities consider this doubtful, and attribute any good 
effect from such application to the moist heat or to the 
resins and spirits of the liquid preparations. Mucous 
surfaces, wounds, ulcers, etc., readily absorb opium. 
The local action of the drug is astringent. In the 
mouth the mucous lining is dried, the tongue coated, 
and a sensation of thirst produced. In the stomach 
opium may cause a short period of irritation of the 
nerves, with nausea, but soon sensibility is diminished, 
the secretions checked, sensations of appetite and hunger 
are lost, the digestive powers fail, and the afferent nerves 
are depressed, so that the act of vomiting is produced 
with difficulty, and direct emetics may fail altogether. 

In the intestines opium is sedative and astringent. 
All impressions given to the nerves from the mucous 
membrane are weakened ; the secretions are diminished, 
peristaltic action is checked, and pain relieved. 

Given by the rectum, as in enemata or suppositories, 
opium allays local pain, checks diarrhoea, and acts as an 
antispasmodic, keeping the parts at rest, and preventing 
irritability of the mucous membrane. 

The secretion of bile is diminished and the urine les- 
sened in quantity. The bowels are constipated. The 
skin is the only organ whose action is not decreased by 
opium. Perspiration, instead of being lessened, is ex- 
cited, especially by some preparations, which are de- 
cidedly diaphoretic. 



122 MATERIA MEDIC A FOR NURSES. 

Opium is eliminated by the breath, perspiration, urine, 
and milk. The latter is to be remembered in giving 
opium to a nursing mother. 

The pre-eminent influence of opium is upon the brain 
as a stimulant, hypnotic, and narcotic. These actions 
are more prominent in man than in animals, and in 
highly civilized than in lower races. 

The stimulant effect is noticeable sometimes after a 
medicinal dose, and precedes the hypnotic action by a 
short variable period. In persons who are accustomed 
to large doses of opium the period of stimulation is more 
marked. The nerve centres which preside over the 
imagination are specially affected. The imaginative 
powers are heightened and the will power weakened. 

Opium als ) acts upon the heart as a stimulant, sustain- 
ing and strengthening it. The opium pulse resembles 
the healthy pulse, being strong, moderately slow, and 
regular ; full, compressible, and of moderate length, and 
is not disturbed by change of position, exercise, or men- 
tal agitation — an important difference between the action 
of opium and other cardiac stimulants. 

The anodyne effects of opium depend chiefly on 
morphine, its most important alkaloid. There are some 
differences of action between opium and morphine alone, 
as follows : opium is less soluble than morphine, is more 
slowly absorbed, and the effects last longer ; its local 
action on the intestines is more pronounced ; it reaches 
the bowels directly and is more constipating. For 
this reason it is preferred in many cases of intestinal 
trouble. 

Opium is not as powerful a narcotic as morphine, as 
several of its other alkaloids (thebaine, codeine, and nar- 
cotine) have a more or less e»xciting or convulsant action 
which modifies the whole drug. 

Opium disorders the digestion more than morphine 
and has greater power as a diaphoretic. 

Finally, opium, being of variable strength, is not as 
reliable as morphine, the quantity of which in a given 
dose may be accurately determined. The relative 
strength of opium to morphine is about as \ or J to i. 



THE VEGETABLE KINGDOM. 1 23 

Symptoms of Poisoning. 



The mildest manifestation of opium on the brain is a 
quiet, dreamy state, ending after a short time in sleep, 
either light and natural or heavy, and passing into stupor, 
according to the size of the dose. There is hyperemia 
of the brain in the sleep caused by opium. On awaken- 
ing there may be slight depression with headache and 
languor, caused by imperfect aeration of blood — which is 
in turn the result of diminished respirations — and lasting 
several hours. There may be nausea, or even vomiting, 
or the patient may return at once to the normal condi- 
tion. This is the first stage of opium narcosis. After 
large doses the second stage comes on quickly, or at 
once. The symptoms of this condition are very like 
those of congestion of the brain. 

The pupils are contracted, the face flushed, often 
cyanosed ; the pulse is full, slow, and strong ; the respi- 
rations slow and deep, sometimes stertorous ; the skin is 
usually dry and warm, and unconsciousness is apparently 
complete, though the patient can usually be roused, and 
if so, the breathing becomes more rapid and the face 
regains its natural color. There is usually retention of 
urine. Death does not often occur in this stage of opium 
narcosis. 

The third stage is that of prostration with profound 
coma, from which it may be impossible to rouse the 
patient ; but, if he can be roused and made to speak, his 
answer, though it may not be complete, will be rational, 
and there will be no thickness or indistinctness of artic- 
ulation, as there is in alcoholic poisoning. This is 
characteristic of opium poisoning. The respirations are 
weak, shallow, irregular, and slow ; they may fall to one 
or two in a minute, while in the second stage they may 
frequently be found as low as four or five. The face is 
pallid and cyanosed ; the skin cold and covered with 
perspiration ; the pupils are absolutely contracted, and 
just before death they dilate widely. The pulse becomes 



124 MATERIA MEDIC A FOR NURSES. 

more and more rapid and weak, and death results from 
failure of the respirations. 

Treatment of Poisoning. 

The treatment of opium poisoning is mainly directed 
toward maintaining respiration, and in those cases where 
symptoms of narcotism arise gradually after the giving of 
medicinal doses, it is enough simply to work toward this 
one object, by rousing the patient and trying to keep 
him roused until the effects wear away of themselves. 
Naturally, in the case of narcotism after hypodermic 
injections, emetics would be useless. Black coffee, as 
strong as possible, is given through a tube into the 
stomach, if necessary, or by rectum, as it will sometimes 
be difficult to make the patient swallow. 

In those cases where a large dose has been taken by 
mouth, the stomach must be emptied. A tablespoonful 
of mustard in a glass of warm water may be given, and 
repeated in ten minutes, and gr. xxx. each of ipecac 
and sulphate of zinc may be afterwards given and re- 
peated once or twice at intervals of fifteen minutes, 
with plenty of warm water. If emetics refuse to act 
on the torpid stomach, the stomach-pump must be used, 
but, though it acts better than emetics when fluid prep- 
arations have been taken, it is useless if the solid drug 
has been used. 

After washing out the stomach respiration must be 
supported in every possible way, yet measures which may 
exhaust the patient's strength are to be avoided. Black 
coffee is given as before mentioned. Cold or alternate 
hot and cold douches may be applied to the head and 
chest. Artificial respiration should be kept up untir- 
ingly, for hours if necessary, or the battery may be used. 

The bladder must be emptied by the catheter, to 
prevent re-absorption, and the temperature kept up by 
the application of external heat. 

Various cardiac and respiratory stimulants are given 
hypodermically ; atropine is a physiological antagonist to 
the action of opium on respiration, being the most active 



THE VEGETABLE KINGDOM. 1 25 

known respiratory stimulant ; but it is necessary to regu- 
late the amount given with great precision and with a 
thorough understanding of the entire physiological rela- 
tion of one to the other. Lacking this, it would probably 
be given rashly, and atropine poisoning be added to the 
opium narcosis. For this reason the administration of 
atropine should not be undertaken except under direc- 
tions from a physician. 

There are usually no sequels to opium poisoning. 
The amount which may cause death varies greatly with 
idiosyncrasy or the habits of the patient. Recovery has 
taken place after 55 grains of solid opium and again after 
6 ounces of laudanum had been taken, while 4 grains of 
crude opium have caused death. 

Incidental Effects of Opium. 

Idiosyncrasies are very common in regard to opium, 
especially among delicate nervous women. Severe de- 
pression sometimes follows ordinary doses, marked espe- 
cially by excessive vomiting. In these cases, nausea is 
not felt while the patient is lying down, but recommences 
on rising. Delirium sometimes follows, or retention 
of urine. A common result, noticed when the effects of 
a dose are wearing off, is an itching, sometimes general, 
sometimes confined to the face and especially the nose ; 
and erythema — red stains or blotches, appear on the 
face. Children and old people bear opium badly. With 
children this is accounted for by the disproportionately 
large size of brain ; and women are more susceptible to 
its action than men. 

In conditions where there is severe suffering, much 
larger doses than ordinary can be safely taken, for the 
power of the drug then seems to be spent in overcoming 
the pain. 

Preparations of Opium. 

According to the Pharmacopoeia all the liquid prepa- 
rations of opium, except paregoric, are required to be 
made in a strength cf 10 per cent, opium. 



126 MATERIA MEDIC A FOR NURSES. 

Solid Preparations. 
Extractum Opii. 

Double strength. Dose, gr. J-i. (0.015-0.06 gin.) 
Pilulae Opii. 

Strength, about one grain to one pill. 

It is to be remembered that opium pills, if old, are dry 
and hard to dissolve, and if given in succession may pro- 
duce alarming symptoms by accumulating in the alimen- 
tary canal and dissolving all at once. 

Liquid Preparations. 
Tinctura Opii Camphorata. 
Camphorated Tincture of Opium. 
Paregoric. 

Contains gr. ii. of opium to f i. ; also benzoic acid, 
oil of anise, and camphor. Owing to the camphor it is 
more constipating than the other preparations. 

Dose for an adult, \ i- § ss ; for a baby under one 
year, TTL i.-v. ; for a child under two years, TT[ v.-xv. ; 
under three years, TT], v.-xx. ; under four and five years, 
TTj, v.-xxv. ; under ten years, TT[xx.-xxx. ; under fifteen 
years, Tli xxx.-3i.-ii. 1 

(iT[ x. of paregoric equal gtt. xx. and gr. ^ of opium.) 

Tinctura Opii Deodorati. 
Deodorized Tincture of Opium. 
McMunn's Elixir. 

Contains no narcotine and none of the odorous prin- 
ciples, and is therefore less nauseating than laudanum. 
Dose, TTj, x.-xv. (TT[ x.-gtt. xvii. One grain is represented 
by twelve minims). The strength is 10 <f . 

Tinctura Opii. 
Tincture of Opium. 
Laudanum. 

Dose, TTj, x.-xv. (f\[ x. = gtt. xx.). Strength, 10 <f . 

1 TTL i . = 0.06 gm. ttl v. = o 3 gm. TTJ, x. = 0.65 gm. TTl xv. 
= I. gm. TTJ, xx. = 1.3 gm. TTj, xxv. = 1.5 gm. 



THE VEGETABLE KINGDOM. \2j 

Other Preparations Containing Opium. 

Pulvis Ipecacuanhae et Opii. 
Ipecac and Opium Powder. 
Dover's Powder. 

One powder of ten grains contains gr. i. of opium, gr. i. 
of ipecac, and gr. viii. of sugar of milk. An excellent 
diaphoretic, though somewhat nauseating. 

To be taken at night. Dose, gr. v.-x. (0.3-.65 gm.) 

Tinctura Ipecacuanhae et Opii. 
Tincture of Ipecac and Opium. 

Dover's powder in a liquid form. Strength, 10 f opium. 

Dose, the same as the tincture of opium. 
Tinctura Opii Composita. 
Compound Tincture of Opium. 
Squibb's Diarrhoea Mixture. 

Contains tincture of opium, tincture of capsicum, 
spirits^of camphor, chloroform, and alcohol. 

Dose, 3 i. (4- g m -) 

Alkaloids of Opium. 
Morphina (Morphine). 

The official salts of morphine in dry form are as 
follows : 

Morphinae Acetas. 
Morphine Acetate. 

A white bitter powder, soluble in water in a strength of 
1 to 12 ; made from the hydrochlorate of morphine by 
the action of acetic acid. 

Morphinae Hydrochloras. 
Morphine Hydrochlorate. 

Made by the action of hydrochloric acid ; soluble 1 
part in 24 parts of water. 

Morphinae Sulphas. 
Morphine Sulphate. 

Made by the action of sulphuric acid. Soluble 1 part 
in 24 parts of water. 



128 MATERIA MEDIC A FOR NURSES. 

The dose of all these salts in solution is gr. \-\. 
(0.015-0.008 gm.) 

The present Pharmacopoeia gives no standard solution 
of any morphine salt. The old familiar solution of the 
strength of one v grain to the ounce, called among nurses 
and doctors " U. S.," is no longer official. 

Pulvis Morphinae Compositus. 
Compound Morphine Powder. 
Tully's Powder. 

Ten grains contain gr. -J- of morphine, with camphor, 
liquorice, and calcium carbonate. 
Tinctura Chloroformi et Morphinae. 
Tincture of Chloroform and Morphine. 

Contains a small amount of morphine, with ether, al- 
cohol, oil of peppermint, liquorice, and syrup. 
Dose, Til x. (0.65 gm.) 

Magendie's Solution of Morphine. 

This preparation is not official ; it contains gr. xvi. of 
morphine to § i., and it is used almost entirely hypo- 
dermically. If it is old, or exposed to the air, it develops 
a fungus which unfits it for use. It is not irritating to 
the tissues. 

The analgesic and narcotic action of morphine is 
quickly manifested, coming on usually within half an 
hour after an ordinary dose, sometimes in a few moments. 
The length of time during which these effects last varies 
much with the condition of the patient, the degree of 
pain present, and the extent of toleration of the drug 
which has been established. The average may be put at 
four or five hours. (TTj, x. = gtt. x.) 

Codeina (Codeine). 

Codeine has slightly exciting action on the spinal cord. 
Its hypnotic action is feeble and uncertain. It is not 
constipating, 

Dose, gr. J— i., usually in pill. 

The other alkaloids of opium resemble morphine some- 
what, but are not used in medicine. 






THE VEGETABLE KINGDOM. 1 29 

Narcotine is wrongly named, as it has no narcotic 
power, and on animals acts as a tetanizer. 

Thebaine is a convulsant, almost like strychnine. 

Apomorphinae Hydrochloras. 

Prepared from morphine by the action of hydro- 
chloric acid. An active and certain emetic, which 
acts indirectly or through the vomiting centre in the 
medulla. It may therefore be given hypodermically if 
the patient is unable to swallow. In from five to twenty 
minutes it causes nausea and repeated vomiting. 

If taken by the stomach it does not irritate, and leaves 
no ill after-effects. Very large doses cause prostration 
and paralysis of the voluntary muscles and depression of 
the respiratory centre. 

Small doses are expectorant, but it is not much used 
in this way. 

Expectorant dose, gr. yV~tV- (0.006-0.004 gm.) 

Emetic dose, gr. -J-. (0.012 gm.) 

Emetic dose, hypodermically, gr. t 1 q every 10 minutes. 

Emetic dose, hypodermically, for an infant, gr. ^""tV ', 
and for a child of 10 years, gr. ^. (0.002-0.004-0.003 
gm. 

Nat. Ord. Crucifera. 

Sinapis (Mustard.) 

The mixed and powdered dried ripe seeds of Brassica 
alba and Brassica nigra, grown in temperate regions. 

Black mustard seeds contain various principles, the 
most important one being a volatile oil, oleum sinapis, 
which is set free when water is added. 

It is a pale-yellow or colorless fluid, of intensely pun- 
gent and penetrating odor, burning taste, and a blister- 
ing and corrosive action on the skin. 

White mustard seeds do not possess this volatile oil, 
but contain a rubefacient principle which resembles it, and 
which is set free in the same way on the addition of water. 

Physiological Actions. 

Applied externally, as in poultices, baths, etc., mus- 
tard is a nerve stimulant, rubefacient, and vesicant, 



130 MATERIA MEDIC A FOR NURSES. 

causing redness, heat, and severe burning pain, and, if 
long applied, blistering. Relief of previous pain and 
loss of sensibility to other impressions follow the action 
of mustard. The heart, blood-pressure, respirations, and 
nerve centres generally are first simulated, then quieted, 
and, if vesication has resulted, depressed, even seriously. 
In baths, mustard dilates the vessels of the skin and re- 
lieves the blocd-pressure in congested organs. 

The principles of counter-irritation are, first : that, by 
causing dilatation of the vessels of that part to which ap- 
plication is made, there is contraction of the vessels in 
other parts of the body, especially if there is nervous 
connection between the two ; and following this principle, 
counter-irritants are usually applied at some distance 
from the congested part, as in the use of foot-baths ; 
second, that, by increasing the activity of the circulation, 
counter-irritants promote the re-absorption of inflamma- 
tory products, and for this purpose they are sometimes 
applied directly over the affected region. 

In making mustard paste, the addition of the white of 
an egg modifies the local irritant action, making it more 
easily borne by the skin, and less liable to injure its 
structure, while it does not interfere with the physiologi- 
cal effect. The paste should be mixed only with tepid 
water, as hot water dissipates the volatile oil, vinegar 
destroys it, and alcohol prevents its formation. In- 
ternally, mustard in small amount, as taken with food, 
Stimulates the appetite and gastric circulation. In 
large doses it is a rapidly acting stimulant emetic, 
leaving little or no depression. 

The action of mustard externally must always be 
specially watched with comatose patients, as injury to 
the skin does not show at first in a state of sluggish 
circulation, and may become serious before it is noticed. 
Emetic dose, f ss., in warm water. 

Nat. Ord. Polygalacece. 
Senega (Snake-Root). 

The dried root of Polygala Senega, of the Middle and 
Southern United States. The acti\ e principle is saponin, 



THE VEGETABLE KINGDOM. \$\ 

a glucoside, allied to digitonin, one of the active princi- 
ples of digitalis. 

Senega acts upon the bronchial mucous membrane as 
a stimulant expectorant and also stimulates the skin 
and kidneys, increasing the amount of urine and its solid 
constituents. It is not readily absorbed by the stomach. 
Small doses impair digestion, and large ones irritate the 
stomach and intestines, causing nausea, vomiting, and 
diarrhoea. 

Preparations of Senega. 

Extractum Senegae. 

Dose, gr. v.-x. (0.3-0.65 gm.) 
Abstractum Senegae Fl. 

Dose, TTL x.-xv. 
Syrupus Senegas. 

Dose, 3 i- 

Nat. Ord. Sapindacece. 

Guarana (Brazilian Cocoa). 

The seeds^ of Paulhnia sorbilis. They contain an 
active principle, guaranine, which is similar to caffeine. 

Extractum Guaranae Fl. 

Dose, 3 l.-ii. (4.-8. gm.) 

Nat. Ord. Erythroxylacea. 

Coca. 

The coca tree (Erythroxylon Coca) is cultivated in 
South America. The dried leaves have a bitter, aromatic 
taste, and an odor like tea. They are extensively used 
by the natives, who chew them as a stimulant during 
hard labor, scarcity of food, etc. They contain an alka- 
loid, cocaine, the active principle. 

Coca in small doses is stimulant, tonic, and restora- 
tive. It strengthens the heart and respirations, raises 
arterial tension, increases the supply of blood to the 
brain, producing wakefulness, and lessens the sensations 



132 MATERIA MEDIC A FOR NURSES. 

of hunger and fatigue. It has diuretic action, and de- 
creases the amount of urea by checking tissue waste. 
Under the influence of coca, or cocaine, the skin is 
flushed, the circulation excited, and a sense of heat and 
perspiration result. 

Cocaine in solution has decided action as a local 
anaesthetic. If applied to a mucous surface, as the 
tongue or conjunctiva, or if given hypodermically, it 
quickly paralyzes the sensory nerves and contracts the 
small vessels, producing a state of local anaemia and 
anaesthesia, which lasts for fifteen minutes, or longer, in 
proportion to the strength of the application. It is often 
used in this way for minor surgical operations (amputa- 
tion of a finger ; opening of an abscess, etc.). Applied 
to the eye it causes dilatation of the pupil, which begins in 
a few minutes, reaches its height in about an hour, and 
returns to the normal state in twenty-four hours. 

Symptoms of Poisoning. 

Overdoses weaken the heart and the pulse becomes 
small, rapid, and intermittent. There is a feeling of 
tightness about the chest ; the respirations are slow and 
shallow, and the skin cold and clammy. There are 
sometimes hallucinations and delirium. Poisonous doses 
paralyze the sensory nerves and the respiratory centre. 
This has been shown by experiments on animals, no 
fatal cases in man being known. 

Five grains taken by mouth have caused alarming 
symptoms : loss of sight, nausea, incoherent speech, 
cyanosis, rapid intermittent pulse, and a feeling of suffo- 
cation. In treating severe depression from the use of 
cocaine, alcohol, opium, and nitrite of amyl are used as 
antagonists. 

The habit of constantly taking large doses of cocaine 
is readily formed, and produces emaciation, insomnia, 
and disordered digestion. If carried to excess the intel- 
lect is weakened, even to insanity. The victim has an 
uncertain gait, an apathetic air, eyes sunken and sur- 
rounded with a deep purple ring, trembling lips, teeth 
crusted with a greenish deposit, a peculiar blackness 



THE VEGETABLE KINGDOM. 1 33 

around the corners of the mouth, and excessive fetor of 
the breath. Ascites sometimes appears, and death may 
result from a general wasting of the vital powers. 

Preparations of Coca. 

Extractum Cocae Fluidum. 
Fluid Extract of Coca. 

Dose, 3 ss.-ii., moderately diluted. (2.-8. gm.) 

Cocainae Hydrochloras. 
Cocaine Hydrochlorate. 

The solution of the hydrochlorate of cocaine is the 
familiar one, and is put up in varying strength, 2 per 
cent., 4 per cent., and 8 per cent., approximately. The 
2-per-cent. solution has gr. x. to § i. ; therefore 3 i. 
equals gr. i\. The 4-per-cent. solution, the most com- 
mon one, contains gr. 2 J in 3 i, gr ij- in TTj, xxx., gr. 
\ in TTt xv. One grain is represented by TT[ xxiv., and 
the minims and drops are equal. Cocaine is used hypo- 
dermically as a heart stimulant. 

Dose, gr. -J-i. (0.008-0.06 gm.) 

Nat. Ord. Linacea. 
Linseed (Flaxseed). 

The dried ripe seeds of the flax. They contain a fixed 
oil and a quantity of mucilage. The whole seeds are 
used to make a demulcent drink, flaxseed tea ; ground 
into meal, they are used for poultices ; and the oil, mixed 
with equal parts of lime-water, is called Carron oil, and 
is used as a dressing for burns. 
Flaxseed Tea. 

Pour one quart of boiling water over four ounces of 
flaxseed (whole). Let it boil for half an hour, and after- 
wards stand near the fire for fifteen or twenty minutes. 
Strain and sweeten it, and flavor with lemon-juice. 
Flaxseed Poultice. 

A flaxseed poultice must be made over a fire, or alco- 
hol lamp. The water must be boiling actively when 
the meal is added, and must continue to boil until the 



134 MATERIA MEDIC A FOR NURSES. 

poultice is done. Flaxseed bubbles and seethes at a 
point of heat below the boiling point of water, and is 
thus deceptive if it is added to the water in the first 
place. It must be sprinkled in with the left hand and 
stirred constantly with the right. If added in handfuls 
the poultice will be lumpy. When it has reached a 
proper consistency, not thick enough to be stiff, nor 
thin enough to run, it must be taken off the fire and 
thoroughly beaten for several minutes. This makes it 
light and spongy. A perfect poultice will leave the 
spoon and vessel clean, and reaches this point by being 
sufficiently boiled. 

Flaxseed poultices are sedative. They relieve pain 
and relax spasm. In the early stages of an inflamma- 
tion they draw the blood to the surface and relieve con- 
gestion. Resolution may thus be brought about and the 
formation of pus avoided. 

If suppuration has begun, the action of poultices 
favors the process. It is, therefore, not considered well 
to use them in the later stages of an acute inflammation, 
as is often seen done in the home treatment of abscesses, 
etc. Such cases should be brought to a physician for 
proper treatment, and this is the more important if the 
inflammation is near a joint. 

Poultices, if kept up too long, give the tissues a 
flabby, water-soaked appearance ; make granulations 
pale, flabby, and unhealthy ; depress the circulation and 
the vaso-motor system, and may impair seriously the 
vitality of the part. 

Nat. Ord. Malvacecz. 

Gossypium (Cotton-Wool ; Cotton). 

Cotton-wool is too familiar to need description, and 
is introduced here as the first step in making collodion. 

Pyroxylinum (Gun-Cotton). 

Made by treating cotton-wool with sulphuric and nitric 
acids. It is explosive, and~ is soluble in a mixture ot 
ether and alcohol. 



THE VEGETABLE KINGDOM. 135 

Collodium (Collodion). 

Made by dissolving pyroxylin in a mixture of stronger 
ether and stronger alcohol. When applied to the skin, 
after evaporation of the ether and alcohol, a colorless, 
transparent, contractile film is deposited, impervious (o 
air and moisture. The vapor of collodion is inflammable. 

Collodium Flexile. 
Flexible Collodion. 

Contains Canada turpentine and a small proportion of 
castor oil. The oil renders the film pliable, and prevents 
its contraction. 

Collodium Cantharidatum. 
Vesicating Collodion. 

Collodion containing a solution of cantharides, and 
used as a vesicant. The skin must be washed with the 
same precautions used in applying cantharides, and from 
three to five coats painted on with a brush, letting each 
dry separately. The action of the vesicating collodion is 
hastened by spraying with ether after application. 

Collodium Stypticum. 
Styptic Collodion. 

Contains tannic acid, ether, alcohol, and collodion. 

Nat. Ord. Byttneriacecz. 

Oleum Theobromatis (Oil of Theobroma). 
Cacao Butter. 

An oil expressed from the seeds of Theobroma Cacao, 
the chocolate tree. It has the consistency of tallow, and 
melts at the temperature of the body. It does not be- 
come rancid, and is used as an unguent and in the pre- 
paration of suppositories. 



136 MATERIA MEDICA FOR NURSES. 

Nat. Ord. Rutacea. 
Buchu. 

The leaves of Barosma crenulata and other species of 
the same family, from Southern Africa. They contain 
volatile oil and a bitter extract. 

Buchu is slightly tonic, owing to its bitter principle. 
It is also a stimulating diuretic, and has some alter- 
ative power. 

Extractum Buchu Fluidum. 

Dose, 3 i., well diluted. (4. gm.) 

Ruta (Rue). 

The leaves of Ruta graveolens, or garden rue. The 
active principle is a volatile oil, of hot and bitter taste. 
Rue is "a carminative and emmenagogue. In large 
doses it is irritant and will cause abortion. It is less 
powerful than savine. 

Dose of the oil, Oleum Rutse, TTJ, i.-iii. (0.06-0.2 gm). 

Pilocarpus (Jaborandi.) 

Jaborandi, if applied to the conjunctiva, causes con- 
traction of the pupil, with disturbances of vision. The 
effect is shown in about ten minutes, and in an hour or 
two after begins to pass off, disappearing entirely within 
twenty-four hours. Pilocarpine, or the preparations of 
jaborandi, enter the blood rapidly, and pass into the tis- 
sues. The most prominent action of the drug is that of 
a prompt and powerful diaphoretic and sialogogue. 
It is also a cardiac and motor depressant. 

When 60 to 90 grains of the infusion of jaborandi are 
given to an adult, after about ten minutes the face and 
neck are flushed, and salivation and perspiration set in. 
These symptoms may appear in five or six minutes after 
a hypodermic injection of the alkaloid. 

Perspiration begins on the face, and extends down- 
ward, lasts from three to five hours, and is profuse in the 



THE VEGETABLE KINGDOM. 1 37 

extreme, amounting to f ix -xv., and becomes alkaline in 
reaction, if it is not so at first. The flow of saliva may 
equal \ x.-xxv. It is sometimes the case that with pro- 
fusion of one secretion there will be scantiness of the 
other. The secretions of the eyes and nose are stimu- 
lated. Sometimes nausea and vomiting are caused. The 
pulse is at first stimulated and quickened, but as dia- 
phoresis goes on it becomes slow and weak. The 
respirations are lowered, and apncea may result from 
an increase in the mucus of the bronchial tubes. The 
temperature falls from i° to 4 , and a depressed condi- 
tion results, with pallor, chilliness, and general weakness, 
lasting for several hours. 

The pupils are contracted, and vision impaired. 

Jaborandi, in small doses, is diuretic, and increases 
the elimination of urea. 

The patient undergoing the diaphoretic action of 
jaborandi should be placed between blankets, and the 
depression is to be combated by external heat, which 
also assists the diaphoretic action of the drug. Within 
three to six hours the effects have passed away. 

Children bear relatively larger doses without harm than 
do adults. 

Preparations. 

Extractum Pilocarpi Fl. 

More certain in action, less nauseating and disagree- 
able to take than the infusion of jaborandi, which was 
formerly used. Dose, V\ xv- 3 i. (TT[ x. = gtt. xx.). 

Pilocarpine Hydrochloras. 
Pilocarpine Hydrochlorate. 

A solution for hypodermic use. Dose, gr. -J— J-. 
(0.008-0.02 gm.) 

Nat. Ord. Simarubacece. 

Quassia. 

The wood of Picraena excelsa, a tree of Jamaica. 



138 MATERIA ME DIC A EOR NURSES. 

The active principle, quassin, is an intensely bitter 
neutral substance. 

Quassia is one of the most active of simple bitters 
and Stomachics. It contains no tannin, and is there- 
fore not incompatible with iron. 

An infusion of quassia used as an enema is anthel- 
mintic. 

Preparations. 

Tinctura Quassiae. 
Tincture of Quassia. 

Strength, 1 to 9. Dose, TT^, xx.-3i. (1.3-4. gm.) 

Extractum Quassiae Fl. 
Fluid Ext. of Quassia. 

Dose, TTX v.-x. Both preparations to be diluted rather 
freely and given before meals. (0.3-0.65 gm.) 

Nat. Ord. Rkamnacecz. 
Cascara Sagrada. 
Sacred Bark; California Buckthorn. 

The bark of Rhamnus purshiana. 

Cascara in small doses is tonic and stomachic ; in 
large dose, laxative or cathartic, with active and 
certain effect. It sometimes causes griping pain. 

Ext. Cascara Sagradae Fl. 
Fluid Ext. of Cascara. 

May be given at night, or one or two hours after meals. 
Dose, at night, 3 ss. ; after meals, TT[ x.-xv., well diluted. 
(0.65-2. gm.) 

Nat. Ord. Amyridacece. 

Myrrha (Myrrh). 

A gum resin which exudes from the stem of a species 
of balsam. Tincture of myrrh, like other oleo-resins, is 



THE VEGETABLE KINGDOM. 1 39 

mildy stimulant and disinfectant, and is useful in 
making mouth washes for the sick. 

It has some action as a stomachic, and in certain 
cases aids the action of purgatives. It is also a uterine 
stimulant and emmenagogue. 

Nat. Ord. Leguminosa. 

Tragacantha (Tragacanth). 

A gum resin which exudes from the stem of astragalus 
gummifera ; used to make a demulcent drink. 

Scoparius (Broom-Tops). 

The fresh and dried tops of Cystisus Scoparius, of 
Europe and the United States. They contain two active 
principles, scoparine and sparteine. Scoparius is an 
excellent diuretic. 

Dose of the infusion, | i. 

Sparteinae Sulphas. 
Sparteine Sulphate. 

A liquid alkaloid obtained from Scoparius. It is 
colorless, with bitter taste, and with sulphuric acid 
forms a crystalline salt, which is soluble in water. 

Physiological Actions. 

Sparteine is slightly hypnotic, but is more important 
as a cardiac stimulant, increasing the force and regu- 
larity of the pulse. It acts very quickly, its influence 
over a weak, failing heart being shown within half an 
hour to one hour, but it does not last long, wearing off 
in four or five hours. 

It is not considered equal to digitalis, but it is often 
given with it and with other more enduring but slowly 
acting stimulants. It is not accumulative, and does not 
disturb digestion nor impair the appetite. 

It has not the diuretic action of scoparius. In larger 



I4O MATERIA MEDIC A FOR NURSES. 

doses it is a depressant to the brain and spinal cord, and 
causes death by paralysis of the respiratory centre. Doses 
of four to six grains produce vertigo, headache, palpi- 
tations, and a feeling of formication in the extremities ; 
and larger doses have caused loss of power in the legs, 
sensations of heat, with flushed face and severe pain 
about the heart, the symptoms beginning in about twenty 
minutes and reaching their climax in four or five hours. 
Dose, gr. g V-ii- (0.003-0.1 gm.) 

Copaiba (Copaiba). 

The oleo-resin of a species of Brazilian tree. It is 
stimulating to mucous membranes, as those of the 
bronchi and alimentary canal. It is also a Stimulant 
diuretic of somewhat irritating character. It is stated 
that its use has been followed in some instances by 
strangury and in others by suppression of urine. 

Dose, TTl x.-xx. (0.65-1.3 gm.), on sugar, or made into 
an emulsion with syrup and gum arabic. 

Glycyrrhiza (Liquorice-Root). 

The root of Glycyrrhiza glabra, cultivated in England. 
Licorice is demulcent. It contains grape-sugar, 
starch, resin, and a glucoside named glycyrrhizin. 

Pulvis Glycyrrhizae Compositus. 
Compound Licorice Powder. 

A laxative preparation containing senna, licorice- 
root, fennel, sugar, and sulphur. Its action resembles 
that of castor oil. It is not a hydragogue cathartic, and 
given in moderate doses causes no griping, and acts 
gently — in the morning if given at night ; in from three 
to six hours if given early on an empty stomach. Many 
patients find it nauseous ; it is therefore best to make 
the dose small as possible by diluting it only a little and 
giving afterwards a larger quantity of water. 

Dose, 3 i.-iv. (4.-16. gm.) 



THE VEGETABLE KINGDOM. 141 

Balsamum Peruvianum (Balsam of Peru). 

A balsam exuded from the trunk of Toluifera Pereirse. 
It is a reddish-brown or nearly black liquid, thick and 
syrupy, and insoluble in water. It contains benzoic 
acid, a number of resinous principles, a volatile oil, and 
other constituents. 

It is a vascular stimulant and nerve sedative, 
antiseptic, and disinfectant, and is used externally as 
an application to granulating surfaces. It is not used 
internally, though it has mild action as a carminative 
and as a stimulant and disinfectant expectorant. 

Balsamum Tolutanum (Balsam of Tolu). 

Balsam of tolu is obtained from the trunk of Toluifera 
Balsamum. It is a reddish-yellow, soft, and sticky sub- 
stance of fragrant odor, soluble in alcohol. It yields 
benzoic and cinnamic acids, various resins, etc. Its prop- 
erties are the same as those of balsam of Peru ; but it is 
only used internally as an ingredient of cough mixtures. 

Physostigma (Calabar Bean). 

The dried seeds of Physostigma venenosum, an African 
plant. They contain two alkaloids : calabarine, the less 
important one ; and physostigmine, or eserine, the active 
principle. 

Physiological Actions. 

Applied to the eye, physostigmine is absorbed by the 
conjunctiva, and causes contraction of the pupil, with 
slight twitching of the eyelids, dimness of vision, and 
pain over the eyes. 

Calabar bean acts as a depressant on the medulla and 
spinal cord, but does not affect the cerebrum, the mind 
remaining clear in cases of poisoning. In moderate 
doses it sometimes produces nausea, colic, and increased 
peristaltic motion, resulting in diarrhoea. 

The heart is first stimulated, and then weakened, and 
the same contraction of the pupil takes place after its 
internal use. 



142 MATERIA MEDICA FOR NURSES. 

Symptoms of Poisoning. 

The first symptoms of poisoning are : giddiness, weak 
pulse, muscular feebleness, vomiting, and free purging. 
The respirations become slow and irregular, and death 
results from paralysis of the respiratory centre. 

The poison is treated by emptying the stomach, apply- 
ing external heat, and using' artificial respiration. 
Atropine is a physiological antagonist, and is given in 
doses not larger than gr. T V- 

Recovery has taken place, by means of prompt emesis, 
after a dose of gr. xii. 

Preparations. 

Extractum Physostigmatis. 

Dose, gr. T 1 o~i- (0.006-0.012 gm.) 
Tinctura Physostigmatis. 

Dose, TTl xx.-xl. (% x. = gtt. xiv.) (1.3-2.6 gm.) 
Physostigmine. 

Dose, gr. T V, (0.004 gm.) 

Tamarindus (Tamarinds). 

The preserved pulp of the fruit of Tamarindus Indica. 
Tamarinds are laxative, and are taken like preserves, 
or made into confections with senna. 

Senna. 

The dried leaflets of two varieties of Cassia, from 
Africa and Arabia. The active principle is cathartic 
acid, and there are other unimportant principles. 

Senna is a simple cathartic, and acts as a stimulant to 
the muscular coat of the intestines, producing local reflex 
action, active peristalsis, and free evacuations within four 
or five hours. It acts especially on the colon, and does 
not cause constipation after its action is over. Griping 



THE VEGETABLE KINGDOM. 143 

pains are caused by full doses, but it is usually given in 
combination for the purpose of avoiding this. 

Senna is excreted by the kidneys and the mammary 
glands. Nursing infants in this way feel its action as a 
laxative. 

Preparations. 

Extractum Sennae Fl. 

Dose, 3 ii- 1 ss. (8.-32. gm.) 

Confectio Sennae. 

Tamar-Indien. 

Tropical Fruit Laxative. 

This preparation tends to disorder the digestion. 
Dose, 3 i -ii. (4.-8. gm.). 

Infusum Sennae Compositus. 
Black Draught. 

Contains manna and sulphate of magnesium, and is an 
active hydragogue purgative. Dose, § iv. (256. gm.) 

Syrupus Sennae. 

Dose, 3 i.-iv. (4.-16. gm.) 

Nat. Ord. Rosacea. 

Amygdala Amara (Bitter Almond). 

The ripe seeds of Prunus amygdalus, the bitter almond 
tree. The important principle of the bitter almond is 
a volatile oil, which contains from 4 to 8 $ of hydrocy- 
anic acid, and is highly poisonous. 

The artificial oil of bitter almonds, nitro-benzene, or 
nitro-benzol, is poisonous, and has caused death. 

Rubus (Blackberry). 

The bark of the root of Rubus villosus and other 
varieties of rubus. An astringent, containing 10 $ of 
tannin. 



144 MATERIA MEDIC A FOR NURSES. 

Dose of the fluid extract, V\ x- 3 i. (0.65-4. gm.) •, 
of the syrup, 3 i.- § i. (4- _ 3 2 . g m -) 

Prunus Virginiana (Wild Cherry). 

The bark obtained from Prunus serotina, or wild 
cherry tree, contains tannic acid, a bitter extractive 
amygdalin, and emulsin, and these two latter principles, 
when brought into contact in watery solution, produce 
hydrocyanic acid. 

The effect of cherry bark, as administered, is due to 
the tannic and hydrocyanic acids and the bitter extrac- 
tive. None of these, however, are present in sufficient 
amount to make a strong impression, and the only physio- 
logical action is that of a mild astringent and tonic. 
The syrup of wild cherry bark is much used as the basis 
of cough mixtures. There is also a fluid extract given 
in doses of 3 ss- 3 i. (2.-4. gm.) 

Nat. Ord. Myrtacece. 
Eucalyptus (Blue Gum Tree). 

The blue gum tree, Eucalyptus globulus, is found in 
southern countries. From a hygienic point of view it is 
unusually interesting. It has an enormous capacity for 
absorbing water from the soil. One tree, it is said, will 
absorb in twenty-four hours ten times its weight of 
water. Swamps are therefore drained and transformed 
into dry land by planting the eucalyptus. It is also 
believed that it purifies the air of malarial districts by 
absorbing poisonous emanations and by giving forth 
balsamic principles. 

It is largely cultivated in southern malarial localities ; 
for instance, in the Roman Campagna, portions of which 
it has transformed into habitable regions. 

The leaves only are official. They yield tannic acid, 
the principles turpene, cymol, eucalyptol, and others. 

Physiological Actions. 

It is tonic to appetite and digestion, and stimulates 



THE VEGETABLE KINGDOM. 1 45 

all the juices of the alimentary tract. It is destructive 
to low forms of life, antimalarial, diaphoretic, and a 
Stimulant expectorant. It is eliminated by the skin, 
mucous membranes, and kidneys. It is given when qui- 
nine cannot be administered, its effect being much the 
same. In excessive doses, symptoms similar to those 
caused by overdosing with quinine appear, as headache, 
palpitations, and numbness of the limbs. 



Preparations. 

Oleum Eucalypti. 
Oil of Eucalyptus. 

The essential oil, which is the active principle of the 
drug. Dose, TT[ v.-x., in emulsion or capsule. 

Extractum Eucalypti Fluidum. 
Fluid Extract of Eucalyptus. 

Dose, TIj, x.-3i. (0.65-4. gm.) 

Granatum (Pomegranate Rind). 

The bark of the pomegranate root contains four alka- 
loids, of which the two most important are pelletierine 
and isopelletierine. The drug is an efficient taenia- 
cide, or remedy for tapeworm. It is capable of causing 
symptoms of some severity, such as muscular depression 
almost amounting to paralysis, and is not considered a 
safe drug for children. The taste is very unpleasant. 
In administration the patient fasts for twelve or eighteen 
hours previously to taking the dose. The decoction of 
the fresh root is used in a strength of two ounces to a 
pint of water. This quantity is divided into several 
doses, and taken at intervals of an hour. Pelletierine is 
given in the same way. A cathartic is given afterwards, 
no food being allowed until the treatment is over. 

Dose of pelletierine, gr. x.-xx. (0.65-1.3 gm.) 



I46 MATERIA MEDICA FOR NURSES. 

Caryophyllus (Cloves). 

The unopened flowers of Eugenia aromatica, a tree of 
the Molucca Islands. The spice made from them con- 
tains oleum caryophyllag, or oil or cloves, a pungent, 
volatile oil. It is aromatic and carminative, and 
locally to some extent anaesthetic, as shown by its 
popular use in the cavity of an aching tooth. Clove tea 
is made with spice and boiling water, 3 ii.-Oi. 

Jambul. 

The drug obtained from the bark of Eugenia jambo- 
lana, an East Indian tree, is used in India as a stom- 
achic astringent, and also as a specific in diabetes. 

Dose of the fluid extract, TT[ x.-xxx. (0.65-2. gm.) 

Nat. Ord. Cucurbitacece. 
Colocynthis (Colocynth). 

The dried, peeled, and seeded fruit of Citrullus colo- 
cynthis, or bitter cucumber, from Eastern countries. 
The active principle is colocynthin. 

Colocynth is a powerful hydragogue and drastic 
cathartic, irritant, and quickly acting, causing large 
watery evacuations, with griping pains and general de- 
pression. Besides acting as a stimulant to the muscular 
coat of the intestines, it also acts on the intestinal glands 
and on the liver. To avoid the severity of its effects, it 
is always given in combination, and is not suitable as an 
habitual purgative, being irritant to the stomach as well 
as to the bowels. 

Gastro-enteritis is caused by colocynth in poisonous 
quantity, and death has resulted in twenty-four hours 
from a dose of 3 i.- 3 iii- of the powder. 

Preparations. 

Extractum Colocynthidis. 

Purgative dose, gr. iii.-v. (0.2-0.3 & m -) 



THE VEGETABLE KINGDOM. 1 47 

Extractum Colocynthidis Compositus. 
Compound Ext. of Colocynth. 

Contains extract of colocynth, aloes, scammony, and 
cardamom. 

Laxative dose, gr. i.-iii. (0.06-0.2 gm.) 
Purgative dose, gr. v.-xx. (0.3-1.3 gm.) 

Pilulae Catharticae Compositae. 
Compound Cathartic Pills. 

Contains extract of colocynth, mild mercurous chlo- 
ride, extract of jalap, and gamboge. 

Pilulae Catharticae Vegetabiles. 
Vegetable Cathartic Pills. 

Contain compound extract of colocynth, extract of 
hyoscyamus, jalap, leptandra, and resin of podophyllum. 

Elaterinum (Elaterium ; Squirting Cucumber). 

Elaterium is a sediment obtained from the juice of 
Ecballium elaterium, from Greece, and cultivated in 
England. It contains a neutral active principle, elaterin, 
which is the officinal preparation, elaterium being of 
variable strength. 

The most active hydragogue cathartic known, pro- 
ducing excessive watery evacuations in a very short time. 
If the dose is not too large there is little or no pain or 
irritation, although in excess it is a gastro-intestinal 
irritant It is also irritant if applied to the skin. The 
purgative action of elaterium is exhausting, and the con- 
dition of the patient must be watched. Catharsis is also 
produced when it is injected hypodermically, but it can- 
not be safely used in this way, as it is very irritant to 
the tissues, and has been followed by tetanus. 

Preparations. 

Elaterium. 

Dose, gr. f (0.01 gm.) 



I48 MATERIA MEDIC A FOR NURSES. 

Elaterin. 

Dose, gr. ¥ V- (°-°°3 g m -) 
Trituratio Elaterini. 

Strength, 1 to 10. Dose, gr. \. (0.03 gm.) 

Pepo (Pumpkin Seeds). 

The seeds of Cucurbita pepo, or ordinary pumpkin, 
are useful as a remedy for tapeworm, being considered 
more efficient than Felix mas, and quite harmless. The 
dose of the expressed oil is half an ounce, given in three 
doses on an empty stomach, the patient having fasted 
on the day before ; or two ounces of the seeds may be 
beaten into an emulsion with sugar and water and taken 
with the same precaution. A cathartic follows. 

Bryonia (Bryony). 

The roots of two European vines furnish the drug 
bryonia, whose active principle is a bitter glucoside, 
bryonin. 

Physiological Actions. 

Bryonia is very irritating to mucous and serous mem- 
branes. It is an active diuretic, a drastic purgative, 
and cardiac depressant. In large doses it has caused 
severe inflammation of the linings of the stomach and 
intestines, vesical tenesmus, and congestions of the liver 
and kidneys. Poisonous doses cause cerebral symptoms 
like those of meningitis, and small doses may cause 
headache and flushing of the face. 

Preparations. 

Tinctura Bryoniae. 
Tincture of Bryonia. 

Dose, TTi v.- 3 i. (0.3-4. gm.) 
Bryonin. 

Dose, gr. \-%. (0.01-0.03 gm.) 



THE VEGETABLE KINGDOM. 1 49 

Nat. Ord. Umbelliferce. 

Conium (Spotted Hemlock). 

The fruit and flowers of Conium maculatum, belonging 
to Europe and naturalized in the United States. They 
have an odor resembling that of mice. The active 
principle is conine, a very volatile alkaloid, freely soluble 
in alcohol and ether, and slightly so in water. On ex- 
posure to the air it decomposes, and this change is 
assisted by heat. 

Physiological Actions. 

Conium is a motor depressant, paralyzing the motor 
nerves from below upward. It affects the respiratory 
centre, paralyzing it. The cardiac and vascular centres 
are not specially influenced. The brain is not affected 
but remains clear. 

When conium is taken in doses just large enough to 
make an impression, the first effect noticed is muscular 
weakness in the legs. The feet feel weighed down, or 
as if made of lead ; the knees weak and unable to bear 
the body, giving an intense desire to lie down, and the 
patient cannot walk, but staggers and falls. 

The eyelids are affected and drop over the eyes ; the 
vision is disordered, and there is frontal headache, with 
a feeling of heat, or of weight and pressure, in the head. 

Conium is used as an antispasmodic ; also some- 
times as an analgesic, and as a calmative in conditions 
of hysterical and maniacal excitement. It is well borne 
by children. 

Symptoms of Poisoning. 

In serious poisoning the symptoms mentioned above 
are all intensified. The pupils dilate ; the pulse, at first 
diminished, afterwards becomes more rapid. The res- 
piratory centre is paralyzed, and death results from 
asphyxia in a very short time — in one case in a few 
moments. There are but few recorded cases of fatal 



150 MATERIA MEDICA FOR NURSES. 

poisoning. Hemlock was the state poison of Athens in 
the time of Socrates, and the means of his death. 

Treatment of Poisoning. 

No physiological antidote to conium is known. The 
stomach must be emptied and tannic acid given, 
stimulants employed and external heat applied, and 
artificial respiration practised as long as there is any 
heart action. 

Preparations. 

Extractum Conii Fluidum. 

The best preparation. Dose, TTl i.-ii. (0.06-0.12 gm.) 
Conine. 

Dose, TTl T 1 o - iii- 5 or g r - tV _ iV (0.001-0.006 gm). 

Asafcetida. 

A gum resin obtained by incising the root of different 
species of Ferula, of Afghanistan. It contains a volatile 
oil, a resin, and gum. The oil is complex, but consists 
largely of the essential oil of garlic, to which it owes its 
unpleasant odor. The resin also yields sulphur. 

Physiological Actions. 

Asafcetida has, in the stomach and alimentary canal, 
the stimulant and disinfectant action belonging to 
volatile oils and resins ; but while most others are pleas- 
ant to the taste, it is exceedingly nauseous and disagree- 
able. The mental influence of this nauseous impression, 
combined with its physiological action, renders asafcetida 
a nerve stimulant, antispasmodic, and calmative 
in hysterical conditions. 

It is a carminative, and in enemata dispels gas, stops 
convulsions, and relieves constipation. It has some 
slight action as a stimulant and disinfectant ex- 
pectorant. The volatile oil is excreted by the urine, 
perspiration, and breath. 



THE VEGETABLE KINGDOM. 151 

Preparations. 

Pilulae Asafoetidae. 

Gr. iii! in each. Dose, ii.-iv., pills. 

Mistura Asafoetidae. 
Milk of Asafoetida. 

Dose, 1 ss.-i. For use in enemata, § i.-iii. 

Tinctura Asafoetidae. 

Strength, § ii.-Oj. Dose, J ss.-i. (16.-32. gm.) 

Ammoniacum (Ammoniac). 

A gum resin exuded from the stem of Dorema Ammo- 
niacum, of Persia. 

The physiological actions are unimportant. It is a local 
irritant and in large doses produces vomiting and purg- 
ing. It is a disinfectant expectorant, being excreted 
by the bronchial mucous membrane, and is used ex- 
ternally as a mild counter-irritant and local stimulant, 
to promote circulation in the skin and aid absorption. 

Preparations. 

Mistura Ammoniaci. 

Dose, § ss. (t6. gm.) 

Emplastrum Ammoniaci. 
Ammoniac Plaster. 

Nat. Ord. Caprifoliacece, 
Viburnum Prunifolium (Black Haw). 

Viburnum acts upon the nerve centres of the uterus 
and ovaries as a sedative and tonic, and is given to 
correct pain and irritation arising from these sources. 

Viburnum opulus is useful in the same way. 

Dose of the fluid extract, "fil xx- 3 i. (1.3-4. gm.) 



152 MATERIA MEDIC A FOR NURSES. 

Nat. Ord. Rubiacea. 
Cinchona. 

The trees belonging to the genus Cinchona are found 
native in South America, on mountains at a height of 
5000 to 10,000 feet, and they are being successfully cul- 
tivated in other countries. The bark is the part used in 
medicine. 

There are many varieties of the tree, the most impor- 
tant being Cinchona succirubra, from which ' v red bark" 
is obtained, and Cinchona Calisaya, from which comes 
the " yellow " or " calisaya bark." A bark called " pale 
bark " is obtained from two minor varieties, and, finally, 
under the general name " cinchona " or " Peruvian 
bark " are included all other varieties of the tree yield- 
ing two or three per cent, of the alkaloids which contain 
crystallizable salts. 

Cinchona contains four principal alkaloids : quinine, 
the most important ; quinidine, the strongest anti-peri- 
odic, but existing in very small quantities ; cinchonine, 
about half the strength of quinine ; and cinchonidine, 
a little stronger than cinchonine. 

The yellow bark contains most quinine, the pale bark 
most cinchonine, and the red bark about equal quantities 
of each. Beside these important alkaloids and a number 
of unimportant ones, cinchona bark contains tannic and 
other acids, a resinous substance, coloring matter, etc. 

Physiological Actions. 

The preparations of cinchona bark as a whole are used 
as bitter stomachics and tonics. 

They are too bulky to be used as antipyretics or anti- 
periodics if quinine can be obtained. They have some 
astringent action, due to the tannin they contain. 

Preparations. 

Infusum Cinchonae. 
Infusion of Cinchona. 

Strength, 1 to 16.6. Dose, § i. (32. gm.) 



THE VEGETABLE KINGDOM. 1 53 

Tinctura Cinchonae. 

Strength, 1 to 5. Dose, 3 i- — ii- (4.-8. gm.) 
Tinctura Cinchonae Compositus. 
Huxham's Tincture. 

Contains cinchona, glycerine, bitter orange-peel, ser- 
pentaria, and alcohol. Dose, 3 i- 1 ss. (4.-16. gm.) 
Extractum Cinchonae Fluidum. 

Dose, TTl v.-xv. (TT[ x. = gtt. xx.). (0.3-1. gm.) 
The preparations of cinchona are given half an hour 
before meals. 

Quinina (Quinine). 

Quinine is prepared from the powdered cinchona bark 
by various chemical processes, in the course of which an 
alkali and sulphuric acid are both used. 

Alkalies, and their carbonates, and tannic acid are in- 
compatible with quinine and the other alkaloids of cin- 
chona. The alkalies precipitate them from solution, and 
tannin forms with them insoluble compounds. 

One grain of dilute sulphuric acid will dissolve one 
grain of quinine. 

Physiological Actions. 

Quinine arrests some processes of fermentation and 
decomposition, and might, except for its cost, be used ac 
a local antiseptic and disinfectant. It is readily 
absorbed, and is frequently given by rectum ; it is also 
used hypodermically, though it is very irritating and 
liable to produce abscesses. 

In small doses it is a powerful bitter stomachic and 
general tonic, stimulating digestion and increasing appe- 
tite. In large doses it may irritate and cause nausea and 
vomiting, or even gastritis. 

Quinine may be found in the blood a few minutes after 
being taken, and retards oxygenation. It enters the tis- 
sues quickly and is excreted slowly, several days being 
required. The maximum effect of a large dose is reached 
in about five hours. Small doses quicken the heart a^ad 



154 MATERIA MEDIC A FOR NURSES. 

raise the blood pressure. Large ones depress the heart, 
diminish the force and frequency of its contractions, and 
lower blood pressure. The respirations are also depressed 
by large doses. 

Quinine acts strikingly on the nerve centres. Small 
doses stimulate the brain and increase the activity of the 
mind, while slight overdoses produce headache and 
ringing in the ears, with deafness, more or less pro- 
nounced. This deafness usually passes off quickly, but 
may be permanent. Full doses intensify these symp- 
toms, and cause severe pain, constriction, and fullness in 
the head, confusion of the mental faculties, intense 
nervous irritability, giddiness, disorders of vision, and 
general prostration from depression of the spinal cord 
and circulation. 

The pre-eminent power of quinine is shown in its 
control over malarial poisoning as a specific, anti- 
periodic, and prophylactic. (A medicine to be pro- 
phylactic must belong either to the class of restoratives, 
supplying a deficiency of some natural and essential con- 
dition of the body, or to the class of germicides, prevent- 
ing disease by destroying the injurious agent.) 

Quinine has some power as an oxytocic, contracting 
the uterus. In times past it was taught that it was capa- 
ble of producing abortion, but the weight of evidence is 
believed by most authorities to be against this theory. 

Incidental Effects. 

Eruptions of the skin are sometimes observed after the 
use of quinine, even in small doses. A rash resembling 
that of scarlet-fever may appear, followed by severe itch- 
ing and smarting, and desquamating finally. More rarely 
the eruption resembles urticaria, popularly known as 
"hives" or "nettle-rash." Occasionally irritaiion of the 
urinary organs is caused, with pain, congestion of the 
kidneys, or even hemorrhage. This is more liable to 
occur with old people. Idiosyncrasy exists in a marked 
degree with some persons, in regard to quinine, forbid- 
ding the use of even the smallest doses. 

If much prostration follows the administration of qui- 
nine, strong black coffee with brandy is the best antidote. 



THE VEGETABLE KINGDOM. I 55 

In giving quinine, ringing in the ears and deafness are 
the first symptoms to be looked for. 

Quininae Sulphas. 
Quinine Sulphate. 

Usually given in pills or capsules on account of the 
bitter taste. Sometimes, when rapid action is desired, it 
is given in solution. The taste is very persistent and is 
better removed by a piece of dry bread, or an olive, than 
anything else. The powdered sulphate may be given in 
sherry wine. 

Quinine pills should not be more than ten days old, as 
then they become so dry and hard as to be useless, pass- 
ing through the alimentary canal without dissolving. 
Quinine should be given on an empty stomach, or after 
the process of digestion is partly over. If a patient is 
on milk diet quinine should not be given in solution 
near the milk, as it is very liable to cause vomiting. 
Otherwise there is no incompatibility between quinine 
and milk. 

Tonic dose, gr. i -v. (0.06-0.3 g m -) 

Antipyretic or antiperiodic dose, gr. x.-xxx. (0.6- 
2. gm.) 

Warburg's Tincture. 

A preparation with an exceedingly long formula, 
containing over a dozen drugs of vegetable origin, with 
a certain proportion of quinine, the most active ingredi- 
ent (between 9 and 10 grains to the ounce). It is used 
as a diaphoretic, and is best given at night. 

Dose, § ss. (16. gm.) 



Ipecacuanha (Ipecac). 

The dried root of Cephaelis Ipecacuanha, of Brazil. 
Ipecac contains from J to 1 ^ of the active principle, 
emetine, and also a glucoside, starch, gum, etc. 



I56 MATERIA MEDIC A FOR NURSES. 

Physiological Actions. 

Externally, powdered ipecac irritates the skin, causing 
a pustular eruption. Mucous membranes are similarly 
irritated, and an increased bronchial and nasal secretion, 
sneezing, etc., follows its local application. Taken in- 
ternally, it tends to soften and liquefy hard and tenacious 
mucous secretions. 

In the stomach ipecac in very small doses (gr. J) is a 
gastric Stimulant, increasing local circulation and 
secretion. In these minute doses it checks vomiting. 

In large doses it is a familiar emetic, safe and prompt, 
and non-depressing. Its action is partly direct and 
partly indirect, the act of vomiting being promoted both 
by local action on the stomach walls, and by stimulation 
through the influence of emetine of the vomiting centre 
in the medulla. 

The emesis caused by ipecac takes place in from 
twenty to thirty minutes after administration, and occurs 
usually only once. There is but very little nausea before 
or with the act of vomiting, nor is it followed by ex- 
haustion. It is accompanied by a decided increase in the 
secretions of the gastric and bronchial mucous mem- 
branes, and the sputum thus being made more fluid, with 
the expulsive act there is a general clearing out of the 
bronchial tubes, the trachea, and the nasal cavities. 

Ipecac, as an emetic, is between sulphate of zinc and 
tartar emetic, not being as prompt as the first, nor as 
nauseating as the second. It is not powerful enough to 
give alone in cases of poisoning, but is then used as 
an aid to other emetics. It is very suitable for children, 
and they bear it in relatively large doses. 

Ipecac is a sedative expectorant, a direct chola- 
gogue, increasing the flow of bile, and a diaphoretic. 



Preparations. 

llvis Ipecacuat 
>wdered Ipecac 

Dose, gr. xx. (1.3 gm.) 



Pulvis Ipecacuanhae. 
Powdered Ipecac. 



THE VEGETABLE KINGDOM. I $7 

Syrupus Ipecacuanhae. 

Strength, 5 parts fluid ext. to 100. Dose for infant, 
3 ss.-ii. - (2.-8. gm.) 

Vinum Ipecacuanhae. 

Strength, 1 part fluid ext. to 7 white wine. Dose, 3 ss.-ii. 
Extractum Ipecacuanhas Fluidum. 

Emetic dose for adult, TT[ xxx. (TT1 x. = gtt. xx.). (2. gm.) 
Emetine. 

Dose, gr. f-J. (0.01-0.03 gm.) 

All these preparations are best given with plenty of 
warm water, in cases of poisoning ; with croupy children, 
however, swallowing being difficult, it is best not to di- 
lute the dose, or but very little. 

Catechu. 

An extract from the wood of Acacia Catechu, from the 
East Indies. It contains kino-tannic and catechinic 
acids, and is a strong astringent. 

Tinctura Catechu Compositus. 

Dose, 3 i.-iii. (4.-12. gm.) 

Coffea Arabica (Coffee Plant). 

The seeds of the coffee plant, grown m Arabia, yield 
the alkaloid caffeine (which is also obtained from plants 
belonging to different families, viz., Paullinia sorbilis, 
guarana). The coffee seeds also contain sugar, tannic 
acid, caffeic acid, a volatile oil, etc. 

The qualities of coffee as a beverage are too familiar 
to need mention. In moderation, and when well made, 
it aids digestion and has laxative effect. In excess, or 
when improperly made and allowed to boil, it causes 
dyspepsia by the astringent action of its tannic acid. 



158 MATERIA MEDICA FOR NURSES. 

Caffeine. 

Caffeine is distinguished by containing more nitrogen 
than almost any other vegetable principle. It is absorbed 
unchanged into the circulation, and is a stimulant to 
the brain and heart, producing wakefulness, with a clear, 
vigorous state of the intellect, and strengthening the 
contraction of the heart. 

It resembles digitalis in its action as a cardiac stimu- 
lant, but acts more promptly and is more transitory in 
its effects. 

It has no decided cumulative tendency, and does not 
disagree with the stomach. It acts as a diuretic by 
stimulating the cells of the kidneys, as well as by its 
action on the heart and circulation. 

It has been known to cause, after doses of moderate 
size, nervous wakefulness and restlessness, tremulousness, 
frequent pulse, confused thought, and visions passing in 
a constant train. These symptoms have lasted for several 
hours. 

In large doses it has caused poisonous though never 
fatal symptoms, such as muscular tremor, a burning 
feeling in the throat, • palpitations with rapid, violent 
pulse and short, quick respirations ; giddiness, nausea, 
disordered vision, and marked diuresis. 

Dose of caffeine, gr. v.-xx. (0.3-1.3 gm.) 

Nat. Ord. Ternstromiacece. 
Camellia Thea (Tea Plant). 

The leaves of the tea plant, grown in China, contain 
theine, the active principle ; tannic acid, and a volatile 
oil. Theine was formerly considered to be identical 
with caffeine, but investigators have recently pronounced 
them to be different. 

Tea is stimulating" and refreshing. Used to excess 
it weakens the digestive system and causes constipation, 
depresses the heart and vaso-motor nerves, producing 
neuralgic pains. In cases of poisoning, when tannin is 
needed, it may sometimes be most quickly procured in 



THE VEGETABLE KINGDOM. 1 59 

the form of strong, rank tea. By boiling it hard and 
squeezing dry the leaves, the tannin is extracted as 
thoroughly as possible, and the tea is given, without 
sugar or milk, in large quantities. 

Nat. Ord. Valerianacetz. 
Valeriana (Valerian). 

The dried rhizome and roots of Valeriana officinalis. 
The active principles are a volatile oil and valerianic 
acid. The latter is found in many other plants, in cod- 
liver oil, and may be derived from amylic alcohol. 

Valerian is a carminative, circulatory stimulant, 
and anti-spasmodic. In nervous cases it sometimes 
acts successfully as an hypnotic. Large doses ( 3 ii.-iv.) 
may cause nausea, vomiting, and colic, a quickened 
pulse, and a feeling of formication in hands and feet. 

Preparations. 

Tinctura Valerianae. 

Strength, I ii. to Oj. Dose, 3i.-iiL (4.-12. gm.) 
Extractum Valerianae Fluidum. 

Dose, 3 i. (4. g m -) 

Tinctura Valerianae Ammoniata. 
Ammoniated Tincture. 

Strength, § ii. to Oj. Dose, 3 i.-iii. (4.-12. gm.) 

Nat. Ord. Composite. 
Santonica (Levant Wormseed). 

The dried flower-heads of Artemisia pauciflora, of 
Asia Minor. The active principle is santonin, and there 
is also a compound volatile oil resembling camphor in 
its action. 



160 MATERIA MEDIC A EOR NURSES. 

Santonin is an anthelmintic, acting especially on the 
ascaris lumbricoides, or round worm. In overdoses it 
produces disturbances of vision and of consciousness. 
Objects appear at first to be blue, then yellow. There 
are tremors, aphasia, and sometimes convulsions. The 
respirations become feeble, and the pulse is reduced. 

It is necessary, in giving it, to watch its action, that 
these symptoms may be avoided. 

It is excreted by the bowels and by the kidneys, and 
discolors the urine, making it saffron or reddish. There 
have been numerous cases of fatal poisoning among 
children from santonin. Alarming symptoms have been 
caused by gr. ii in a child eight years old, and a dose of 
gr. ii. to a child of five years caused death. 

Dose, gr. J-v. (0.015-0.3 gm.) 

Eupatorium (Thoroughwort). 

The herbal parts of a coarse plant yield this drug, 
whose chief action is as a sudorific. The infusion is 
given very hot, in doses of one-half or one tumbler full, 
the patient being warmly covered in bed, and free dia- 
phoresis results. The taste is very unpleasant. 

Taraxacum (Dandelion). 

The root of the dandelion is a simple bitter and 
mild laxative. 

Extractum Taraxaci Fluidum. 

Dose, 3 i.-ii., after meals. (4.-8. gm.) 

Tanacetum (Tansy). 

The common tansy contains a volatile oil, its active 
principle. It is a stimulant emmenagogue and is 
capable of producing abortion. It is a dangerous drug, 
one teaspoonful of the oil having produced severe symp- 
toms of poisoning, such as abdominal pain, unconscious- 
ness, convulsions, and in one instance death. 

Dose of the oil, Oleum Tanaceti, TT[ i.-iii. (0.06-0.2 gm.) 



THE VEGETABLE KINGDOM. l6l 

Arnicae Flores ; Arnicae Radix. 

The Arnica montana, or leopard's bane, grows in 
Northern Europe and Asia and in the Northwestern 
United States. The root and flowers contain two alka- 
loids and the ammonia compound, trimethylamine, 
which is found in cod-liver oil and in ergot, and may 
also be obtained from various decomposing albuminous 
substances. 

Externally arnica is Stimulating and irritant, in- 
creasing the circulation of the skin. It sometimes 
causes excessive redness and eczema, and must be used 
with care. 

The diluted tincture promotes the absorption of blood 
which has effused into the tissues, as after a blow, and 
prevents swelling. 

Internally, in small doses, arnica is slightly stimulating 
to the heart, the skin, and kidneys. 

In larger doses it is a cardiac depressant, and in 
doses equal to f i. of the tincture it has caused the pois- 
onous symptoms of gastro-intestinal irritation ; cold dry 
skin ; feeble fluttering pulse, lowered sometimes to 60 ; 
and occasionally vomiting and purging, with final col- 
lapse. It should never be applied to an open wound. 

Preparations. 

Tinctura Arnicae Flores. 
Tincture of Arnica Flowers. 

Strength, 20 %. 

Tinctura Arnicae Radix. 
Tincture of Arnica Root. 

Strength, 10 <f . 

Both preparations used externally must be diluted, 
applied on a piece of flannel to the inflamed part, and 
covered with a bandage. 

Dose, TT[v.-xxx. (fTl x. = gtt. xv.). (0.3-2. gm.) 



1 62 MATERIA MEDIC A FOR NURSES. 

Extractum Arnicae Fluidum. 

Dose, Tf[ v.-xv. (0.3-1. gm.) 

Emplastrum Arnicae. 
Arnica Plaster. 

Strength, one third of the extract. 

Grindelia (Grindelia). 

The leaves and flowering tops of a California plant. 
It is a stimulant expectorant and a diuretic ; in 

large doses depressant, causing nausea and vomiting, 
and lowering the rate of the heart, temperature, and res- 
pirations. It is used in asthma and whooping-cough. 

In cases of poisoning by Rhus toxicodendron, or poison 
ivy, it is said to be an excellent remedy, the fluid extract 
being applied locally. 

Dose of the fluid extract, TTj, v.- 3 i. (0.3-4. gm.) 

Nat. Ord. Lobeliacea. 
Lobelia (Indian Tobacco). 

The leaves and tops of Lobelia inflata, of the United 
States. The active principle is called lobeline. 

Lobelia is a motor-depressant and anti-spas- 
modic. In small doses it stimulates the alimentary 
canal, and in full doses irritates it, causing pain, vomit- 
ing, purging, and general depression. 

Large doses cause, in addition, cold sweats, muscular 
tremors, feeble pulse, and stupor, with coma and col- 
lapse. It has frequently caused death, which occurs by 
paralysis of the respiratory centre. It is very seldom 
used, on account of its very depressing action. 

The treatment of poisoning consists in washing out 
the stomach with a warm solution of tannic acid (or 
warm, strong tea), the application of external heat, 
and stimulation by mustard, friction, etc. ; and the use 
of alcoholic stimulants, ammonia, and opium. 



THE VEGETABLE KINGDOM. 1 63 

Preparations. 

Tinctura Lobeliae. 

Strength, 20 <f . Dose, TT[ x.-xx. (0.65-1.3 gm.) 
Extractum Lobeliae Fluidum. 

Dose, TT[ i.-v. (TTj, i. = gtt. i.). (0.06-0.3 g m -) 

Nat. Ord. Styracacecz. 
Benzoinum (Benzoin). 

The thickened juice of Styrax benzoin, a tree of Peru. 
It is soluble in alcohol ; not readily soluble in water. 
Benzoin is a balsamic resin, containing from 12 to 15 ^ 
of benzoic acid. It is antiseptic and disinfectant, and 
is said to have more power than salicylic acid to destroy 
bacteria and prevent putrefaction. 

Applied to the skin, it has a stimulating and heal- 
ing action. Inhaled, or applied in solid form to the 
nose, it irritates the nasal and bronchial mucous mem- 
branes, but in proper solution acts on them only as 
a gentle stimulant. Taken internally it is diaphoretic, 
increases the urine and makes it more acid, and raises 
the pulse rate. It is excreted by the kidneys, partly as 
hippuric acid, and partly unchanged. 

Preparations. 

Acidum Benzoicum. 
Benzoic Acid. 

Dose, gr. x.-xxx. (0.65-2. gm.) 

Tinctura Benzoini. 

Strength, 20 <f>. Dose, 3 ss.-i. (2.-4. gm.) 

Tinctura Benzoini Composita. 
Friar's Balsam. 

For external use ; it contains benzoin, aloes, styrax, 
balsam of tolu, and alcohol. 



164 MATERIA MEDIC A FOR NURSES. 

Ammonii \ 

Lithii v Benzoas. 

Sodii ) 

Dose, gr. v.-xxx. (0.3-2. gm.) 

Nat. Ord. Oleacece. 
Oleum Olivae (Olive Oil). 

The oil expressed from the fruit of Olea Europaea. 
Olive oil is composed of a fluid oil, olein ; a solid oil, 
palmitin ; with oleic and palmitic acids. 

Used externally by inunction, it is absorbed by the 
lymphatics, and has some nutritive value. 

As a mechanical application it is used both externally 
and internally in the treatment of burns and corrosive 
poisons. It acts as a laxative, and is used for this pur- 
pose in enemata, tending to soften the faecal mass and 
assist in its expulsion. Oils in general are changed into 
carbonic acid and water in the system, and so excreted, 
but an excess will appear unchanged in the urine. 

Nat. Ord. Loganiacece. 
Spigelia (Pink-Root). 

Spigelia is an anthelmintic and purgative, and acts on 
the round worm. 

Extractum Spigeliae Fluidum. 

Dose, TTJ, x - 3 ii. (0.65-8. gm.) 

Gelsemium (Yellow Jessamine). 

The root of Gelsemium sempervirens, of the Southern 
United States. The alkaloid gelsemium and gelseminic 
acid are the important constituents. 



THE VEGETABLE KINGDOM. 1 65 

Physiological Actions. 

Gelsemium is a motor depressant and anti- 
spasmodic, acting by direct influence on the spinal 
cord. In medicinal doses it is sedative and dia- 
phoretic. 

The smallest active quantity (TTJ, v.-xv.) causes a 
languid feeling, with slight reduction of the strength and 
frequency of the pulse. If the amount be increased, 
pain over the eyes, some disturbance of vision, and diz- 
ziness result, with increased perspiration It has a 
peculiar nervous effect on some people, making them cry 
without knowing why. 

Symptoms of Poisoning. 

Poisonous doses ( 3 i. of the fluid extract) produce, in 
addition to these symptoms, great muscular weakness, 
affecting especially the flexors of the arms. 

The gait also is affected, and becomes staggering. The 
jaw drops, and articulation fails. There is marked 
effect on the sight : double vision, partial or complete 
blindness may develop ; sometimes a squint is produced; 
the eyelid droops ; the pupil dilates. 

There is profuse perspiration, cold surface and sub- 
normal temperature, and a condition of general anaesthe- 
sia. The pulse is thready and feeble, and death finally 
results from paralysis of the respiratory muscles. Con- 
sciousness remains until carbonic-acid narcosis begins as 
the result of asphyxia. 

Gelsemium is rapidly diffused, and the effects appear 
within half an hour, and, after medicinal doses, disap- 
pear within two or three hours. 

Death, when it occurs, may do so in a few hours, and 
has been known to result from taking one sixth of a 
grain. 

Treatment of Poisoning. 

Poisonous symptoms are treated by emetics, alcoholic 
stimulants, external heat, electricity, and artificial respi- 
ration, if necessary. 



1 66 MATERIA MEDIC A FOR NURSES. 

Preparations. 

Extractum Gelsemii Fluidum. 

Dose, TT[ v. (TT1 x. = gtt. xxv.). (0.3 gm.) 
Tinctura Gelsemii. 

Strength, 1 to 6.6. Dose, TT], x.-xxx. (0.65-2. gm.) 

Nux Vomica (Poison Nut ; Quaker Buttons). 

The seeds of Strychnos Nux-vomica, an East Indian 
tree. The active principle is the alkaloid, strychnine, an 
important poison. Two other important principles are 
brucine and igasuric acid. Brucine is of half the strength 
of strychnine. 

Physiological Actions. 

Nux vomica in medicinal doses is tonic, with the 
qualities of bitter stomachics ; it increases appetite, 
aids digestion, and promotes peristalsis. It also stimu- 
lates respiration, the heart, and vaso-motor centres. 
These actions are largely due to the presence and in- 
fluence of strychnine. Strychnine enters the system 
rapidly, especially the nervous tissues, on which its pre- 
eminent action, that of a motor excitant, is shown. It 
is excreted very slowly, not disappearing from the 
tissues for several days, and therefore accumulates in the 
system when given in continuous doses, even small ones. 

The power of strychnine in regard to the nervous sys- 
tem is exerted on the motor centres of the spinal cord 
and all the important nerve centres in the medulla. 

The first constitutional symptoms are a feeling of 
restlessness, with slight trembling of the extremities. 
After a full dose (gr. yV), there are noticeable muscular 
twitching and jerking of the limbs, slight stiffness of the 
jaw, a tense feeling about the head, stricture of the 
throat and chest, shuddering, and a feeling of anxiety. 

Symptoms of Poisoning. 

After poisonous doses (gr. \ for an adult) violent 
symptoms come on very suddenly, probably within 



THE VEGETABLE KINGDOM. 1 67 

fifteen minutes, with tonic convulsions resembling the 
spasm of tetanus. The legs are rigid, extended, and the 
feet everted, or the body may be bent backward until the 
head and heels meet (opisthotonos). The arms are bent, 
and hands clinched ; the eyes open and staring. The 
corners of the mouth are drawn up by the muscles in a 
mechanical grin, the " risus sardonicus," which gives a 
ghastly unmeaning expression, and the face — at first 
pale — presently becomes livid from asphyxia. 

Between the paroxysms there is a period of relaxation 
and quiet, but the slightest sound, or touch, or breath of 
air brings on the spasms again instantly by reflex action, 
owing to the condition of intense irritability. 

In cases which terminate fatally the spasms succeed 
each other quickly, and death takes place in two or three 
hours from paralysis of the respiratory muscles. The 
mind usually remains clear up to the last. Sometimes 
asphyxia produces insensibility just before death. 

Strychnine convulsions resemble tetanic and hysterical 
convulsions in some particulars. The special points of 
difference are as follows : 

Strychnine. 

The convulsions begin with a restless, excited state ; 
the special senses are sharpened. Muscular symptoms 
come on very rapidly, either beginning in the extremities 
or appearing simultaneously over the body. The jaw is 
the last part affected and the first relaxed. The eyes are 
open, and the muscles are relaxed between the con- 
vulsions. 

Tetanus. 

The symptoms come on gradually, with pain and stiff- 
ness of the back of the neck and occasional slight mus- 
cular twitchings. The jaw is the first part affected, and 
is rigid (trismus, or lock-jaw). There is a permanent 
state of general muscular rigidity. 

Hysteria. 

Begins with weakness and blindness. The muscular 
symptoms begin with stiffness of the neck. The extrem- 



1 68 MATERIA MEDIC A FOR NURSES. 

ities are affected last. The jaw is set before a convul- 
sion and remains fixed between them. The eyes are 
closed 

Treatment of Poisoning. 

In treating strychnine poisoning, tannic acid or a 
soluble iodine salt is given as an antidote, followed 
quickly by emetics, as the compounds thus formed are 
not permanent. The bladder must be emptied to prevent 
re-absorption ; then absolute quiet is of the greatest 
importance. Inhalations of chloroform are used, with 
full doses of chloral and bromide of potassium given 
internally. 

Precautions. 

In giving strychnine, the possibility of its cumulative 
action must always be kept in mind as a grave feature. 
It is more likely to develop if the medicine is in pill 
form than if in solution. With the liquid preparation 
of iron, strychnine, and quinine, the danger exists also, 
as the strychnine is apt to precipitate. It must always 
therefore be well shaken. Strychnine is more effective 
with old people. 

The first constitutional symptoms are to be looked for 
with care : twitching, trembling, starting, or stiffness of 
the muscles. It is of great importance to know exactly 
when they begin, especially when, as is often the case, 
the orders received are to push the medicine to the 
utmost limit. 

Preparations of Nux Vomica. 

Abstractum Nucis Vomicae. 
Abstract of Nux Vomica. 

Dose, gr. i.-ii. (0.06-0.12 gm.) " 

Tinctura Nucis Vomicae. 
Tincture of Nux Vomica. 

Strength, 20 per cent. Five minims of the tincture 
represent 2 -J-g- grain of strychnine. 

Dose, TT[ x.-xxv. (fTj, x. = gtt. xxv.). (0.65-1.6 gm.) 



THE VEGETABLE KINGDOM. 1 69 

Extractum Nucis Vomicae Fluidum. 
Fl. Ext. of Nux Vomica. 

Dose, Til ii.-iii. (TIj, x. = gtt. xxv.). (0.13-0.2 gm.) 

Extractum Nucis Vomicae, in pill. 

Dose, gr. J- J. (0.015-0.03 gm.) 

All preparations of nux vomica are given before meals. 

Preparations of Strychnine. 

Strychninae Sulphas. 
Strychnine Sulphate. 

Dose, gr. -gVsV (^ x - = gtt. x.). (0.001-0.003 gm.) 
Ferri et Strychninae Citras. 
Iron and Strychnine Citrate. 

Dose, gr. i.-iii. (0.06-2. gm.) 
Syrupus Ferri, Quininae, et Strychninae Phosphatum. 
Syrup of the Phosphate of Iron, Quinine, and Strychnine. 

One part strychnine to 2,500. Dose, 3 i.-ii. (4.-8. gm.) 

Nat. Ord. Gentianacece. 

Gentiana (Gentian). 

The root of Gentiana lutea, the yellow gentian of the 
Alps, furnishes an efficient simple bitter and stom- 
achic tonic. 

Preparations. 

Tinctura Gentianae Composita. 
Compound Tincture of Gentian 

Strength, 10 $. Dose, 3i.-3iv. (4.-16. gm.) 
Extractum Gentianae Fluidum. 
Fluid Extract of Gentian. 

Dose, HI x.-xxx. (0.65-2. gm.) 

Mistura Gentianae Alkalina. 
Alkaline Mixture of Gentian. 

Contains soda bicarb., dilute hydrocyanic acid, and 
gentian. 



170 MATERIA MEDIC A FOR NURSES. 

Nat. Ord. Convolvulacece. 
Scammonium (Scammony). 

The root of Convolvulus scammonia yields an exudate 
from which is obtained a resin, having properties as a 
drastic purgative. The chief ingredient of the resin 
is called jalapin, and is probably the same as the con- 
volvulin of jalap. 

The dose of the resin of scammony is gr. ii.-x. (0.13 
-0.65 gm.) 

Jalapa (Jalap). 

Obtained from the tuber of Ipomsea jalapa, a vine 
growing in Mexico. The active principle is a double 
resin, or one separable into two, called jalapin and con- 
volvulin, the latter being the most important. Jalap is a 
hydragogue cathartic, and creates a feeling of nausea. 
In overdoses it causes severe vomiting and purging. The 
stools produced by its action are large and watery. It is 
seldom used alone, but is often combined with calomel. 

The compound powder, Pulvis Jalapse Compositus, 
contains jalap and cream of tartar. 

Nat. Ord. Afiocynacecz. 

Strophanthus (Arrow-Poison). 

The seeds of Strophanthus hispidus, of Africa. The 
active principle is a glucoside named strophanthin. It 
exists in the seeds in a strength of 8 or 10 </ . 
Physiological Actions. 

Strophanthus enters the blood and acts directly on 
muscular tissue as a tonic, increasing its contractile, 
power, and, in poisonous doses, paralyzing and leaving 
it in a state of tetanic-like spasm, — not through the 
agency of the nervous mechanism, but by direct influ- 
ence on the muscle itself. This tonic and Stimulant 
action is quickly felt by the heart, receiving as it does in 
a short time all the blood of the body, and thus feeling 
the action of the whole amount of strophanthus con- 
tained in it. The beats become less frequent and the 
cardiac contractions strengthened. 



THE VEGETABLE KINGDOM. \J \ 

Strophanthus resembles digitalis in its action on the 
heart, but it is not as lasting a stimulant, though acting 
more quickly. It differs from it also in not affecting the 
vaso-motor nerves. It is not irritating to the alimentary 
canal, and is not cumulative. It acts as a diuretic by 
increasing the supply of blood to the kidneys. 

Preparations. 

Tinctura Strophanthi. 

Dose, TTj, v.-x. (TT[ x. = gtt. xx.). (0.3-0.6 gm.) 
Strophanthin, for hypodermic use. 

Dose, gr. gWo- (0.003-0.001 gm.) 

Nat. Ord. Solanacea. 
Belladonnas Foiia ; Belladonnas Radix. 
Deadly Nightshade. 

The leaves and root of Atropa Belladonna, a perennial 
plant, native of Great Britain, and cultivated in this 
country. Belladonna contains two alkaloids : bellado- 
nine, of no special importance ; and atropine, the active 
principle, to which the medicinal and poisonous proper- 
ties of the drug are owing. 

Physiological Actions. 

Alone or in a watery solution belladonna (or atropine) 
is not absorbed by the skin, but when combined with 
alcohol, glycerine, or camphor, it is readily so absorbed, 
and even more quickly by mucous membranes and in- 
flamed surfaces ; so that physiological symptoms, from 
the first slight dryness of the throat to evidence of severe 
poisoning, may be produced by external applications. 

Used in this way, belladonna acts upon the ends of 
the sensory nerves as an anaesthetic, relieving pain, as 
is seen in the action of belladonna plasters. This seda- 
tive power, exerted over the nerves which control the 
sweat glands, produces the familiar effect of drying up 
the secretion of milk and checking the action of the skin. 



172 MATERIA ME DIC A FOR NURSES. 

Taken internally, belladonna enters the blood and 
reaches the tissues with rapidity ; and in the case of 
atropine alone absorption is even more quickly accom- 
plished. Elimination takes place by the urine, and 
quickly, atropine appearing unchanged in from ten to 
twenty hours. 

The Stimulant and tonic powers of belladonna, 
which are very strong, are exerted over the whole sym- 
pathetic system and unstriped or involuntary muscular 
fibre ; and its sedative, anodyne actions are directed 
toward the motor system. It is a mydriatic, dilating 
the pupils ; an anti-spasmodic, and the most important 
respiratory stimulant known, keeping up the activity 
of the respiratory centre while at the same time allaying 
the irritability of the respiratory nerves. 

It has but little control over severe pain, and is not, 
strictly speaking, an hypnotic, though it sometimes acts as 
one indirectly by removing conditions which prevented 
sleep. It has a peculiar effect on the brain, causing ex- 
citability and in large doses narcotism. 

As a cardiac stimulant it weakens the force of the 
inhibitory apparatus, derived from the cerebro-spinal 
system, which retards the heart ; and promotes the 
activity of the accelerator apparatus, derived from the 
sympathetic system, which excites the heart. 

The secretion of saliva is checked by belladonna, and 
this causes a dryness of the mouth and throat which is 
diagnostic and is watched for as one of the first signs of 
constitutional impression. 

When small doses of belladonna or atropia are given, 
the respirations become deeper and more frequent. 
The pulse, at first slowed for a short time, afterwards 
becomes strong and rapid, its rapidity being somewhat 
out of proportion to the rate of the respirations. 

After full doses it may rise as high as twice its former 
number of beats. The small vessels are more energeti- 
cally contracted, and with the impetus to the circulation 
the temperature rises \° or i°. The pupils are dilated 
and vision disordered ; the face flushed ; the mouth 
and throat are dry ; the tongue is red ; swallowing is 



THE VEGETABLE KINGDOM. 1 73 

difficult ; thirst is present, and a feeling as of sore 
throat. 

Symptoms of Poisoning. 

With larger doses the flush becomes a uniform bright 
red, and resembles the rash of scarlet-fever, except that 
it is not punctated. 1 It spreads first over face and neck, 
extending perhaps over the whole body, and is due to a 
reaction and paralysis of the vaso-motor nerves follow- 
ing the primary stimulation. 

The pupils are bright and widely staring. Headache 
and vertigo, restlessness, illusions, and delirium appear. 
The delirium of belladonna is of a peculiarly active, 
talkative, busy type, accompanied frequently by laughter 
and gayety and associated with physical lassitude. The 
patient is sometimes absorbed with spectral illusions and 
visions, without showing any fear. Occasionally he 
becomes furious, quarrelsome, and maniacal. 

With larger poisonous doses there is loss of muscular 
power, beginning in the lower extremities and becoming 
complete. Sensation is not lost. With excessive pois- 
onous doses convulsions may appear, and shortly before 
death stupor and paralysis develop, and the temperature 
becomes subnormal. The urine, at first increased, 
diminishes and may be entirely suppressed. Death 
results from asphyxia, from the failure of the respiratory 
organs, and there is heart failure as well. 

The smallest fatal dose is not positively known. 
Alarming symptoms have been produced by gr. ^ — fa 
of atropine, and death in fatal cases has occurred as 
early as five hours after taking the poison. 

Treatment of Poisoning. 

The first necessity is to use emetics or the stomach- 
pump. The bladder must be emptied at regular intervals 
to prevent re-absorption. Tannic acid is given ; and 

1 Having the appearance of being formed by exceedingly minute 
dots or points of red. 



174 MATERIA MEDICA FOR NURSES. 

external heat, mustard baths, hot and cold affusions to 
the head, and artificial respiration used. 

Incidental Effects. 

Medicinal doses sometimes produce mild delirium, or 
a feeling of thirst and feverishness. The local applica- 
tion of the drug to the eye sometimes causes an inflam- 
mation on the face about the eyelids. The rash of 
belladonna may appear after small doses, and may 
desquamate ; and a bluish color may be noticed on the 
lips. The dryness of the throat is always to be looked 
for. Children bear belladonna well. 



Preparations of Belladonna. 

Tinctura Belladonnae Foliorum. 
Tincture of Belladonna. 

From the leaves. Strength i in 6.66. Dose, TT], x.-xxx. 
(V\ x. = gtt. xxv.) (0.6-2. gm.) 
Extractum Belladonnae Foliorum Alcoholicum. 
Alcoholic Extract of Belladonna. 

Dose, gr. J-J. (0.008-0.03 gm.) 

Extractum Belladonnae Radicis Fluidum. 
Fluid Extract of Belladonna. 

From the root. Dose, TTJ, i -ii. (0.06-0.13 g m -) 

Emplastrum Belladonnae. 
Belladonna Plaster. 

Equals in strength its weight of belladonna root. 

Atropina. 
Atropine. 

Dose, gr. -fa. (0.001 gm.) 

Atropinae Sulphas. 
Atropine Sulphate. 

Usually given hypodermically, being very soluble in 
water. Dose, gr. y^-^V (m x. = gtt; x.) (0.0005- 
0.0011 gm.) 



THE VEGETABLE KINGDOM. 17$ 

Stramonii Folia ; Stramonii Semen. 
Thorn Apple ; Jamestown Weed. 

The leaves and seeds of Daturia stramonium, a weed 
of this country and Great Britain. The active principle 
is an alkaloid named daturine, which is said to be a com- 
bination of atropine and hyoscyamine. 

Physiological Actions. 

Stramonium resembles belladonna very closely in its 
actions. By small doses the pulse rate is increased, ar- 
terial tension raised, and the respiration quickened. It 
is a mydriatic, and has some power to relieve pain. One 
difference between them is that stramonium is more de- 
pressing to the bronchial nerves. 

The action on the intestinal muscular fibre is the same 
in both ; small doses increasing, and large ones diminish- 
ing, peristalsis. By large doses the tension of the ves- 
sels is relaxed, the pulse still remaining frequent, and 
showing a tendency to intermit. 

Symptoms of Poisoning. 

The symptoms of poisoning are much alike — dilated 
pupils, heightened temperature, rapid pulse, scarlet rash, 
restlessness, delirium, and convulsions, with the fatal 
termination preceded by stupor, paralysis, and asphyxia. 
The pulse in stramonium poisoning is much more in 
clined to irregularity than in atropine poisoning. The 
treatment is the same. Accidental cases are common 
among children. 

Preparations of Stramonium. 

Extractum Stramonii Seminis. 

Dose, gr. J-J". (0.015-0.03 gm.) 

Extractum Stramonii Seminis Fluidum. 
Fluid Extract of Stramonium. 

Dose, TT[ i.-ii. (0.06-0.13 g m -) 



I 76 MA TERTA MED1CA FOR NURSES. 

Tinctura Stramonii Seminis. 
Tincture of Stramonium. 

Strength, 10 percent. Dose, TT[ x.-xx. (0.65-1.3 gm.) 

Stramonii Folia. 
Stramonium Leaves. 

Prepared in the form of cigarettes. They are smoked and 
•the smoke inhaled, having an anti-spasmodic influence 

Hyoscyamus (Henbane). 

The leaves of the second year's growth of Hyoscyamus 
niger, a coarse plant native in Great Britain and natural- 
ized in the United States. The active principles are two in 
number — hyoscyamine, a crystalline, and hyoscine, an 
amorphous, alkaloid. These principles have the same 
chemical formula as atropine, yet are not identical with it. 

Physiological Actions. 

Hyoscyamus is a mydriatic, and has very much the same 
physiological actions as belladonna and stramonium. It 
has greater calmative and hypnotic powers than either 
of the others, due, it is stated, to its hyoscine, which is 
supposed to be much stronger than hyoscyamine, and to 
have marked qualities as a cerebral sedative. 

Like the two former drugs, it is a cardiac and respi- 
ratory stimulant, the pulse under its influence being 
more regular than the pulse of daturine. It has the same 
stimulant action on the muscular fibres of the intestines, 
thus being somewhat laxative. In poisoning, the dry 
mouth, flushed face, dilated pupils, and busy delirium are 
the same as with belladonna and stramonium, "and the 
treatment is the same. Hyoscyamine is rapidly excreted 
by the urine. 

Preparations of Hyoscyamus. 

Tinctura Hyoscyami. 
Tincture of Hyoscyamus. 

Made in a strength of 1 in 6.66. Dose, 3 ss.-ii. (2.-8. gm.) 

Extractum Hyoscyami Fluidum. 
Fluid Extract of Hyoscyamus. 

Dose, gr. i.-iii. (0.06-0.2 gm.) 



THE VEGETABLE KINGDOM. 177 

Hyoscyaminae Sulphas. 
Hyoscyamine Sulphate. 

Dose,.gr. Jq-'i. (0.0016-0.06 gm.) 

Hyoscinae Hydrobromas. 
Hyoscine Hydrobromate. 

Hyoscine is a powerful hypnotic, and differs from 
atropine in reducing the pulse rate. This is the first 
evidence of its action, and is shown in a few moments. 
The fall may be from 8 to 20 beats in a moment, and this 
effect is the last to disappear. Hyoscine does not always 
dilate the pupils. It is eliminated by the urine. 

Dose, gr. T fa-io. (0.0006-0.001 gm.) 

Capsicum (Cayenne Pepper.) 

The fruit of Capsicum fastigiatum, the African pepper. 
The active principle is a very acrid oleoresin which is 
powerfully irritant, being capable of destroying the skin 
if applied to it. Capsicum is a Stimulant stomachic, 
giving, in moderate doses, a pleasant feeling of warmth. 
In overdose it may cause severe pain and inflammation, 
with vomiting and purging. It is useful as a corrective 
in flatulence and slight diarrhoea. 

Preparations. 

Tinctura Capsici. 
Tincture of Capsicum. 

Strength, 5 <f>. Dose, TU 10-30. 

Emplastrum Capsici. 
Capsicum Plaster. 

Tabacum (Tobacco). 

The leaves of Nicotiana Tabacum, a native of tropical 
countries cultivated in the North. 

They contain an exceedingly powerful alkaloid, nico- 
tine ; a volatile oil, nicotiana ; and, in slight propor- 
tions, the following alkaloids, some of which are familiar 



178 MATERIA MEDIC A FOR NURSES. 

as being found in other plants : lupuline, coniine, lobe- 
line, piperidine, pyridine, muscarine, and sparteine ; also 
the alkaloidal compound trimethylamine. 

Tobacco smoke contains but little nicotine, if any, and 
a large proportion of pyridine. 

Nicotine is one of the most violent poisons known, 
acting almost as rapidly as prussic acid. 

Death has followed a toxic dose in three minutes. 
Emetics, tannin, and artificial respiration are to be em- 
ployed in treating the poisoning. Tobacco is no longer 
used in medicine, being seriously depressing in its effects. 

Nat. Ord. Scrophnlariaceoz. 

Digitalis (Purple Foxglove). 

The leaves of the second year's growth of Digitalis 
purpurea, native of Great Britain, and cultivated in this 
country. 

The active principle, digitalin, occurs in two forms, 
one amorphous and the other crystalline, and is com- 
posed of four glucosides. Digitalin is no longer offi- 
cinal, the preparations made from the whole leaf being 
considered more trustworthy. 

Physiological Actions. 

The most important action of digitalis is as a heart 
stimulant and tonic, and is shown in the slowing and 
strengthening of the pulse. This is partly brought about 
by a direct action on the heart-muscle, by which the 
circulation in the organ itself is more efficiently carried 
on ; partly by a strengthening of the inhibitory apparatus, 
which tends to slow the heart ; and partly by a stimulant 
action on the vaso-motor system, by which the arteries 
are more strongly contracted, and, by offering some 
resistance to the force of the heart, excite it to greater 
effort. The result of all this is, that the diastole is 
lengthened, and the systole becomes more energetic. 
Thus the ventricles are better filled and more thoroughly 
emptied, and the beats, reduced in number, gain in 
firmness and strength. 



THE VEGETABLE KINGDOM. Ijg 

When an excessive amount is taken, signs of over- 
stimulation appear, marked by intermittency of the 
pulse or by a fall below normal ; it may be to 40 or 
50 in a minute. In this condition any sudden exertion, 
such as sitting upright, may bring to a climax the grow- 
ing exhaustion of the heart, and the pulse may run up 
to 150 or more, becoming small, weak, and irregular. 
For this reason patients taking digitalis continuously 
must be kept quietly in bed and not allowed to sit up or 
to make any sudden exertion. 

In taking it only occasionally or for a short time there 
is not the same danger. 

Digitalis is also a diuretic, acting through an influ- 
ence on the renal as well as on the general circulation, 
and for this purpose it is also used locally in the form, of 
poultices applied over the kidneys, and made from the 
leaves or with the fluid preparations. Digitalis is elimi- 
nated by the urine, and much more slowly than it is 
absorbed into the system. For this reason, if doses are 
given close together, part of the influence of one may be 
added to that of the next, and the action is intensified 
by so much. But except conditionally in this way, a 
cumulative action of the drug is not acknowledged by 
all authorities. 

Symptoms of Poisoning. 

In cases of poisoning the symptoms begin with violent 
and repeated vomiting of mucus and bile. There is a 
feeling of vertigo, pain, and heat in the head, and dis- 
turbance of vision, fringes of color with a vibratory motion 
being sometimes seen around objects. 

The face is pale, the eyes staring and prominent, 
with dilated pupils and a blue color of the sclerotics. 

There is sometimes salivation, and usually diarrhoea. 
The un'ne may be suppressed. The vomiting continues, 
and great prostration follows. The pulse is irregular, 
small, and weak, yet the beat of the heart may be hard 
and strong. The respirations become rapid and feeble. 
Pains in the limbs and back may be present, There are, 
usually before the end, delirium and stupor, or convul- 



l8o MATERIA ME D1C A FOR NURSES, 

sions. Death occurs from general failure of the circula- 
tion with final paralysis of the heart, and has taken 
place as soon as three quarters of an hour after taking 
the poison. The average time, however, is one or two 
days. Digitalis poisoning of an acute form is not com- 
mon, and in the majority of cases the patient recovers. 
The smallest fatal dose is not known. Twenty grains 
of the extract are known to have caused death in ten 
days. 

Treatment of Poisoning. 

Emetics and cathartics must be given, and tannin in 
large quantities. Alcoholic stimulants are used, but with 
great care, and the most perfect rest and quiet, with a 
perfectly horizontal position, maintained. 

Incidental Effects. 

Digitalis is very bitter, nauseating, and irritant to the 
stomach, and is apt to interfere with digestion, and to 
cause vomiting, with occasional diarrhoea, marked by 
green discharges. These two latter symptoms may also 
be produced by hypodermic administration of the drug. 

Headache and vertigo, fainting, sneezing, and buzzing 
in the ears, are caused by overdoses ; also sparks before 
the eyes and other disturbances of sight ; sleeplessness ; 
fall of temperature ; and irregularity or threadiness of the 
pulse. 

Preparations of Digitalis. 

Infusum Digitalis. 
Infusion of Digitalis. 

Strength, i to 66.6. Dose, 3 i.- § ss. More diuretic 
than stimulant. To be largely diluted. (4.-16. gm.) 

Tinctura Digitalis. 
Tincture of Digitalis. 

Strength, t to 6.66. Dose, TTj, v.-xx. (0.3-1.3 gm.) 



THE VEGETABLE KINGDOM. l8l 

Extractum Digitalis Fluidum. 
Fluid Extract of Digitalis. 

Dose, TT[ i.-ii. (Til i. — gtt. ii.). The tincture and fluid 
extract are more stimulant than diuretic, and are only 
slightly diluted when given. (0.06-0.13 gm.) 

Digitaline. 

Dose, gr. -£$. It has been used hypodermically, but is 
irritating and much more liable to cause abscesses than 
either the tincture or the fluid extract given in the same 
way. (0.0013 gm.) 

Nat. Ord. Labialce. 

Oleum Lavandulae Florum (Oil of Lavender 
Flowers). 

An oil obtained from the flowers of Lavandula offici- 
nalis. 

Tinctura Lavandulae. 
Tincture of Lavender. 

May be pleasantly used, in small quantity, added to 
water for bathing. 

Spiritus Lavandulae Compositus. 
Compound Spirits of Lavender. 

A stomachic and cordial. Dose, 3 ss -ii. (2- 
8. gm.) 

Oleum Menthae Piperita (Oil of Peppermint). 

The oil of the fresh flowering Peppermint. 

Aqua Menthae Piperitae. 

Used as a carminative. Dose, TT[ x -xx., in water 
(TT[ x. = gtt. x.). (0.65-1.3 gm.) 

Menthol. 
Peppermint Camphor. 

A stearoptene obtained from peppermint oil. Used as 
a local anaesthetic in headache, in the form of a pencil. 



1 82 MATERIA MEDIC A FOR NURSES. 

Thymol. 

A stearoptene from the volatile oils of thymus vulgaris 
and other herbs. It is an antiseptic and germicide, 
resembling carbolic acid and oil of turpentine in action. 

Nat. Ord. Polygonacecz. 
Rheum (Rhubarb). 

The root of Rheum officinale, from China. 

Rhubarb contains cathartic acid, a peculiar tannic 
acid, a yellow coloring matter, etc. 

Rhubarb acts entirely on the alimentary canal. In 
small doses it is Stomachic, strengthening appetite and 
digestion. In large doses it is a cathartic, with as- 
tringent after-effects. 

In its purgative action the liver is stimulated as well 
as the intestinal glands, and evacuation takes place in 
six or eight hours, accompanied by some griping pain. 

Preparations of Rhubarb. 

Extractum Rhei Fluidum. 
Fluid Extract of Rhubarb. 

Dose, TT[ xv.-xxx. (fU x. = gtt. xx.) (1.-2. gm.) 

Syrupus Rhei. 
Syrup of Rhubarb. 

Dose, for infants, 3 i. (4. gm.) 

Tinctura Rhei. 
Tincture of Rhubarb. 

Dose, 3 i-ii. (4.-8. gm.) 

Nat. Ord. Lauracece. 

Camphora (Camphor). 

A stearoptene obtained from the wood of Cinnamomum 
Camphora, of China and other Eastern countries. 



THE VEGETABLE KINGDOM. 1 83 

Camphor is one of the most widely diffused of all 
vegetable substances. It is found in pennyroyal, hemp- 
tops, and numbers of other plants. 

Physiological Actions. 

Externally applied, camphor is irritant, stimulating 
the local circulation. It has feeble antiseptic power, 
and is sedative to the nerves after first stimulating them. 
Internally, it acts as a carminative and anti-spas- 
modic, gives increased force and fulness to the pulse, 
and stimulates the cerebro-spinal nerves. When large 
doses (gr. xx.-xxx.) are given, the pulse falls, and a feel- 
ing of lassitude and giddiness is produced. 

Symptoms of Poisoning. 

After poisonous doses (gr. xxx.-lx.) there are faintness 
and headache, vertigo, confused ideas, burning pain in 
the stomach, delirium, convulsions, and insensibility. 
The pulse is small, sometimes slow, again accelerated. 
The skin is pale, cold, and covered with perspiration. 
No death of an adult has occurred with camphor. 

Preparations. 

Aqua Camphorae. 

Strength, 1 to 125. Dose, § ss.-ii. (16.-64. g m -) 
Spiritus Camphorae. 

Strength, 1 to 10. Dose, 3 ss.-i. (2.-4. gm.) 
Linimentum Camphorae. 

Olive oil, 6 parts ; camphor, 1 part. 

Linimentum Saponis. 
Soap Liniment. 

Soap, 10 parts ; camphor, 5 ; alcohol, 70 ; oil of rose- 
mary and water to 100 parts. 

Oleum Camphorae. 

More stimulating than the other preparations. Dose, 
TTL v.-x. (TTL x. = gtt. xx.). (0.3-0.65 gm.) 



1 84 MATERIA MEDIC A FOR NURSES. 

Cinnamomum (Cinnamon). 

The bark of different varieties of the genus cinnamon. 
It contains tannic acid and a yellowish volatile oil, oleum 
cinnamomi. This has a fragrant and pleasant taste, and 
is used to mitigate that of disagreeable drugs. The 
preparations of cinnamon are used as carminatives. 

Pulvis Aromaticus. 
Aromatic Powder. 

Is composed of cinnamon, ginger, cardamom, and nut- 
meg. It is given in doses of gr. x.-xx. (0.65-1.3 gm.) 

Nat. Ord. Aristolochice. 
Serpentaria (Snakeroot). 

The dried rhizome and rootlets of two or three 
varieties of Aristolochise, found in North America. The 
taste and odor resemble camphor. It contains a resin, 
a volatile oil, bitter principle, etc., and is a Stimulant 
tonic. 

Preparations. 

Tinctura Serpentarise. 

Strength, 10 </ . Dose, 3 i. — ii- (4-8. gm.) 
Extractum Serpentaria^ Fluidum. 

Dose, TT[ xx. (1.3 gm.) 

To be given half an hour before meals. 

Coto Bark. 

The bark of trees found in South America, somewhat 
similar to the Cinchona, having an aromatic resinous odor 
and pungent taste. It contains a bitter principle, cotoin, 



THE VEGETABLE KINGDOM. 1 85 

and has astringent action. It is irritant to the .skin and 

mucous membranes. 

Extractum Coto Fluidum. 

Dose, fix i.-xv. (fT[ x . = gtt. xx.). (0.06-1. gm.) 
Should be given in wine or other dilute alcohol, as it 

does not combine with water, but forms a precipitate. 

Cotoin. 

Dose, gr. J-ii. (0.03-0.13 gm.) 

Nat. Ord. Euphorbiacecz. 

Cascarilla. 

The dried bark of Croton Eleuteria, from the Bahamas. 
It contains resins, volatile oils, tannin, a bitter principle, 
named cascarillin, etc. It is an aromatic bitter. 
Infusum Cascarillae. 
Infusion of Cascarilla. 

Strength, § i.-Oj. Dose, a wineglassful before meals. 

Oleum Tiglii (Croton Oil). 

A fixed oil, obtained from the seeds of Croton Tiglium, 
a shrub of Asia. The oil is quite thick and becomes 
more so with age ; deteriorates rapidly in quality and 
should not be kept long, but, if possible, always obtained 
fresh. In color it may vary from a pale yellow to a dark 
reddish-brown. The taste is acid and hot. 

It is a very complex substance, containing several fixed 
oils and volatile acids. It is supposed to contain a vesi- 
cating principle and a distinctly purgative one, but the 
latter has not yet been obtained separate from the others. 
Croton oil is soluble in alcohol. 

Physiological Actions. 

It is a very powerful irritant and vesicant when ex- 
ternally applied, causing burning and redness of the skin 
and an eruption of papules, which in a short time be- 
come pustular. Taken internally it irritates actively ; 



1 86 MATERIA MEDIC A FOR NURSES. 

causes burning in the throat and epigastrium, and has 
a very rapid action as a drastic and hydragogue 
cathartic. 

The bowels are first opened in one or two hours after 
it is taken, and catharsis re-occurs several times within 
twelve hours or more, with great thoroughness, some 
pain, and, usually, a decided degree of prostration. 

The dose, which is usually one or two drops — -some- 
times three or four — may be given on bread-crumbs, or in 
a little glycerine, or on a lump of sugar. 

With unconscious or delirious patients it maybe pi'aced 
directly on the back of the tongue. 

In applying it externally, the amount ordered is taken 
on a bit of flannel, and rubbed into the prescribed spot 
on the skin until there is well-marked redness. The 
eruption appears usually in about four hours ; if it does 
not, the application is repeated. 

It may also be mixed with olive oil or turpentine, 
or combined with liniments, alcohol, or ether. 

The eruption remains for several days, and may, on 
disappearing, leave small cicatrices behind it. 



Symptoms of JPoisoning. 

Though so active in small doses there have not been 
many known instances of fatal poisoning by croton oil. 
Large doses usually provoke immediate vomiting, but 
symptoms when developed are those of gastro-enteritis, 
with violent catharsis and great prostration. 

In some instances, instead of acting in the usual way it 
seems to be absorbed into the blood, and produces nerv- 
ous symptoms, such as palpitation and restlessness, head- 
ache, giddiness, and confusion of ideas. 

Oleum Ricini (Castor Oil). 

The oil expressed from the seeds of Ricinus communis, 
of Calcutta. Castor oil contains several fatty acids, of 
which ricinoleic acid is peculiar to itself. 



THE VEGETABLE KINGDOM. 1 87 

Physiological Actions. 

Externally castor oil is very soothing, and may be 
applied to the eye, or the surface, as a sedative and 
protective. 

Internally it is unirritating to the stomach, if pure, but 
if impure or rancid it may cause nausea and vomiting. 
Aside from this, the odor may provoke nausea even be- 
fore the drug is swallowed, and all pains should be taken 
to avoid this possibility, bypreparingit carefully and hold- 
ing it at the side — not under the patient's nose — until the 
moment comes for swallowing it. 

In the intestines it acts as a simple purgative, and 
here the oil which is not perfectly pure is more efficient. 
It is painless, with sedative and somewhat constipating 
after-effects. 

The muscular coat and the glands of the intestines are 
stimulated, and evacuation results in from three to six 
hours — sometimes sooner. 

It is not a hydragogue cathartic, as it does not appreci- 
ably increase the intestinal secretions. It does not act on 
the liver. 

Ricinoleic acid enters the blood and tissues and is 
removed by all secretions, including the milk, and in 
this way purgation may be produced in a nursing infant. 

Castor oil is very nauseous, and needs to be carefully 
administered, in order that it may be as little offensive 
as possible. To children it is best given in hot sweet- 
ened milk, and adults may take it well in this way ; or 
it may be poured into the centre of an equal quantity of 
glycerine, or given in a little hot coffee, or in brandy ; 
first wetting the sides of the glass, and pouring the oil 
carefully in the centre of 3 ss. brandy, then covering it 
with as much more. In all cases it will be more easily 
taken if the mouth be first rinsed out with brandy or 
peppermint, or any thing pungent which will blunt the 
sense of taste. A little carbonated water afterwards is 
gratefully received, or, to those who like olives, nothing 
is more acceptable after nauseating, or bitter medicines, 
than an olive, when it may be given. 



1 88 MATERIA ME DIC A FOR NURSES. 

Castor oil can be had put up in soft flexible capsules, 
which, though large, are easily swallowed. 

Dose, | ss.-i. (16.-32. gm.) 

Dose for infant one year old, 3 i- — ii- (4.-8. gm.) 

The castor bean is very poisonous. The leaves are 
used as a poultice, applied to the breasts to increase the 
flow of milk. 

Nat. Ord. Salicacece. 
Salicinum (Salicin). 

A glucoside, obtained from the bark of various species 
of Salix or willow tree ; and from Gaultheria procum- 
bens or wintergreen. 

Salicin is a bitter tonic, and to some extent an anti- 
pyretic and antiseptic. Its qualities resemble, though 
in a very mild degree, those of salicylic acid, which is 
derived from it. Salicin is not poisonous. It is very 
insoluble, and is given dry on the tongue or in capsules. 

Dose, gr. xx. (1.3 gm.) 

Oleum Gaultheriae (Oil of Gaultheria). 
Oil of Wintergreen. 

A volatile liquid of penetrating odor. It is composed 
of methyl salicylate, 90 $, and gaultherilene, a hydro 
carbon, 10 </ . In nature it is found in the wintergreen, 
Gaultheria procumbens, called the teaberry. Another 
natural oil almost, if not quite, identical with it, is the 
oil of sweet birch, oleum Betulae volatile, and it is also 
practically the same substance as the synthetically pre- 
pared methyl salicylate. The artificial oil is now largely 
used instead of the natural oil. 

The physiological actions of the oil of gaultheria are 
the same as those of salicylic acid. 

It is given in emulsion or capsules. 

Dose, Tl{ v.-x. (0.3-0.65 gm.) 



THE VEGETABLE KINGDOM. 1 89 

Nat. Ord. Zingiberacece. 
Zingiber (Ginger). 

The dried root stock of Zingiber officinale of the East 
and West Indies. The active principles are an aromatic 
resin and a volatile oil. Ginger is a Stimulant and 
carminative, and is given for colic or cramp. The 
tincture is used in doses of from 3 ss.- 3 i- (2.-4. gm.) in 
hot water ; the fluid extract, ~R[ v.-x. (0.3-0.65 gm.). 

Cardamomum (Cardamoms). 

The fruit of Elettaria repens of the East Indies. The 
seeds contain a fixed and also a volatile aromatic oil. 

Cardamom is a pleasant Stomachic, less heating and 
stimulating than others of its class. 

The tincture is given in doses of 3 i. (4. gm.), and is 
also used as an ingredient in tonic mixtures. 

Cannabis Indica (Indian Hemp). 

Various forms of hemp are sold and used in the East 
as narcotic stimulants. The dried plant is sold in 
Calcutta for smoking, and is called Gunjah. Churrus is 
the resinous exudation with scrapings of the leaves, and 
Hashish is an Arabian preparation. The resin, which 
represents the active principle of hemp, is obtained by 
precipitating the saturated tincture with water containing 
an alkali. 

Physiological Actions. 

Cannabis indica in full doses causes a mental state of 
joyous exhilaration. The subject may fall into a revery, 
while beautiful visions pass before the eyes, or he may 
laugh loudly and give other manifestations of being in 
an ecstatic state. The pupils dilate and the pulse rate 
rises. Partial anaesthesia, local spasms, and convulsions 
may be noticed. After the first stage the subject falls 
into a heavy sleep. The Hindoos are said to induce a 
state of catalepsy by the use of hemp. 



I90 MATERIA MEDIC A FOR NURSES. 

It is not an acute poison, and does not endanger life, 
even when the symptoms produced by it are of an alarm- 
ing character. There are not the unpleasant after-effects 
of opium. The stomach is not affected, nor is there con- 
stipation. The urine, rather than decreasing, is in- 
creased by this drug. 

It has been used to some extent in the treatment of 
insanity, and, aside from that, for the relief of pain and 
as a hypnotic. Various quack medicines advertised as 
" pain killers " contain cannabis. 

The action of the different preparations is variable, 
and it is supposed that much of the supply loses its 
strength during the ocean voyage, and becomes inert. 

Preparations. 

nctura Cannabi 
ncture of Cann, 

Strength, 15 </ . 

ctractum Cannat 
uid Extract of C 

Dose, TTi i.-xxx. (0.06-2. gm.) 



Tinctura Cannabis Indicae. 
Tincture of Cannabis Indica. 



Extractum Cannabis Indicae Fluidum. 
Fluid Extract of Cannabis Indica. 



Nat. Ord. Urticacece. 
Lupulus (Hops). 

The dried strobiles J of Humulus Lupulus, or hop vine, 
cultivated in England. They contain an aromatic vola- 
tile oil, valerol ; a bitter principle, lupulinic acid, etc. 

The former gives a Stimulant action, with after- 
effects that are sedative and sleep-producing. The 
latter gives Stomachic and tonic qualities. Hops are 
also slightly astringent. These various characteristics 
are shown in ales and beers, which are made from hops. 
The heart action is somewhat strengthened and quick- 
ened by hops, and diaphoresis produced. 

Hops are used externally for the relief of pain, either 
as a means of applying moist heat, when they are put 

1 Cones ; from the Latin word, meaning a pine cone. 



THE VEGETABLE KINGDOM. 191 

into bags and wrung out of hot water ; or as dry heat, 
when — also in bags — they are heated through. 
Tinctura Humuli. 

Dose, 1 ss.-ii. (16.-64. g m -) 
Extractum Lupulini Fluidum. 

. Dose, 3 ss.-ii. (2.-8. gm.) 

Hop pillows may be used as a means of inducing 
sleep. The crackling of the hops, which may annoy, 
may be stopped by sprinkling them with alcohol. 

Nat. Ord. Coniferce. 

Pix Burgundica (Burgundy Pitch). 

The exudation from a variety of Norway spruce con- 
tains a resin, oil of turpentine, with other oils, and abi- 
etic acid. 

Burgundy Plaster has 80 <f> of Burgundy pitch. 

Cantharidal Pitch Plaster has 8 parts of cerate of can- 
tharides to 92 of Burgundy pitch. 

Pix Liquida (Tar). 

Tar is an oleoresin distilled from the wood of several 
varieties of pine. It contains pyroligneous acid, methy- 
lic alcohol, acetic acid, creosote, and several hydrocar- 
bons, one of which is called toluene, also oil of tar, with 
other oily bodies, and pyrocatechin. 

The oil of tar, oleum picis liquidse, is used locally and 
by inhalation. It contains a large number of compounds, 
among which are creosote and carbolic acid. 

Tar ointment has 50 </ of tar. The syrup of tar has 
7^- % of tar. 

Oleum Terebinthinae (Oil of Turpentine). 

The oil distilled from turpentine, which is obtained 
from several varieties of pines, chiefly those growing in 
the Southern United States. 

Turpentine, as such, is not used in medicine. It may 



I92 MATERIA MEDIC A. FOR NURSES. 

be separated into the oil and a resin, which, combined 
with lead plaster, forms adhesive plaster. 

Physiological Actions. 

Externally oil of turpentine is Stimulating and very 
irritant, causing redness and heat followed by vesica- 
tion. Its action as a counter-irritant needs to be watched 
with much care, as severe blistering, with depression of 
the general system, may result if its application be too 
long continued. Turpentine is absorbed by the whole 
skin, and enters the blood unchanged. 

Internally in moderate doses its immediate action is 
slightly antiseptic and stimulant to the blood-vessels. 
On the nerves it acts locally as a sedative, and in the 
intestines stimulates the muscular coat, and is, in larger 
doses, a purgative. 

It is a carminative, expelling gas from the intestines, 
and this result is produced as well by outward applica- 
tions and by enemata as when given by mouth. It 
is also an anthelmintic, and is given in enemata for 
thread-worm. 

It is a stimulant diuretic, producing in large doses 
active irritation or congestion of the urinary organs, 
with pain, or it may be strangury or hematuria. The 
strength and rapidity of the pulse are increased by 
turpentine. 

In large doses it has a sedative effect on the brain and 
spinal cord, shown by heaviness and drowsiness, an un- 
steady gait, and debility. The temperature is lowered 
slightly. It is eliminated by the kidneys and lungs, 
giving its own odor to the breath, and the odor of 
violets to the urine. 

Turpentine is capable of causing death, but fatal cases 
are very rare, and there are but few instances even of 
serious poisoning. 

Symptoms of Poisoning. 

The symptoms recorded in such cases include usually 
vomiting and purging, though they do not always exist. 
The pupils are dilated ; the pulse rapid, weak, and 



THE VEGETABLE KINGDOM. 1 93 

irregular. The skin may be either dry or moist ; the 
urine diminished or suppressed altogether, or containing 
blood. In most cases unconsciousness is complete. 

Death in one instance was supposed to have followed 
a dose of § vi., but recovery has taken place in other 
cases after doses nearly as large. 

Oleum Terebinthinae. 
Oil of Turpentine. 

Dose, TT[ x.-xx. (0.65-1.3 gm.) 

It may be given on a lump of sugar. The oil and 
spirits of turpentine are the same, the only difference 
being that spirits have been redistilled. 

Sanitas. 

A disinfectant fluid, put up for use in sick-rooms. It 
is made with oxydized turpentine, and contains per- 
oxide of hydrogen as active principle. It does not stain 
clothing. 

Oleum Juniperi (Oil of Juniper). 

The oil from the full-grown unripe fruit of Juniperus 
communis. 

Juniper resembles turpentine in many of its actions, 
but it is less powerful and also less disagreeable. It is a 
stomachic stimulant and diuretic. In large doses 
it inflames the kidneys and produces strangury. 

Dose, TTL v.-xv. (Til x. = gtt. xx.). (0.3-1. gm.) 

Sabina (Savine). 

The dried tops of a juniper tree of the East. The 
active principle is a volatile oil which is highly stimulat- 
ing when applied locally or given internally. Savine is 
an emmenagogue. In large doses it causes all the 
symptoms of poisoning of the gastro-intestinal irritants, 
and is capable of producing abortion. 



194 MATERIA MEDICA FOR NURSES. 

Preparations. 

Oleum Sabinae. 
Oil of Savine. 

Dose, TTt v.-x. (0.3-0.65 gm.) 

Nat. Ord. Liliacecz. 

Scilla (Squill ; Sea-Onion). 

The bulb of Urginea maritima, a plant of Southern 
Europe. 

Squill increases the strength and reduces the frequency 
of the heart action ; contracts the arterial system and 
raises blood pressure. It is diuretic by means of its 
action on the circulation in the kidneys, and a stimulant 
expectorant, increasing the bronchial secretion by im- 
proving the local circulation and aiding in the expulsion 
of the mucus. 

In overdoses it is irritant, and may cause inflamma- 
tion of the kidneys, with strangury and bloody urine, or 
suppression. It is also irritant to the stomach and intes- 
tines, and even in medicinal doses may disorder diges- 
tion. Full doses cause nausea, vomiting, and diarrhoea. 

Symptoms of Poisoning. 

Fatal poisoning has been caused by squill, in which 
these symptoms were present in an aggravated form, with 
marked depression of the pulse, convulsions and collapse. 
Death has resulted from a dose of 24 grains. 

Treatment of Poisoning. 

The stomach and bowels must be emptied by ipecac 
and castor oil. Large quantities of water should be given 
to overcome the suppression of urine, and the usual 
methods of treating gastro-enteritis and collapse em- 
ployed. 

Preparations. 

Tinctura Scillae. 

Strength, 1 to 6.6. Dose, TTL x.-xx. (0.65-1.3 gm.) 



THE VEGETABLE KINGDOM. 1 95 

Extractum Scillae Fluidum. 

Dose, TT[ i -iii. (TTL i. = gtt. ii.). (0.06-0.2 gm.) 
Syrupus Scillae. 

Dose, 3 ss.-i. (2.-4. gm.) 

Syrupus Scillae Compositus. 

Contains squill, senega, and tartar emetic. Dose, 
TTL x.-xxx. (TT[ x. = gtt. x.). (0.6-2. gm.) 

Sarsaparilla (Sarsaparilla). 

The two varieties of Sarsaparilla used in medicine 
come from Honduras and Brazil, and are obtained from 
the root of Smilax officinalis and other varieties of 
smilax. The drug contains three glucosides, parillin, 
saponin, and sarsaponin. 

Sarsaparilla is widely used, yet no definite physiologi- 
cal actions can be claimed for it. Whatever value it 
may have is as an alterative. The syrup is sometimes 
used to disguise the taste of potassium iodide. 

Preparations. 

Syrupus Sarsaparillae Compositus. 
Compound Syrup of Sarsaparilla. 

Contains sarsaparilla, liquorice root, senna, oil of sas- 
safras, oil of anise, and oil of gaultheria. 
Dose, 1 ss- 3 i. (16.-32. gm.) 

Extractum Sarsaparillae Fluidum Compositum. 
Compound Fluid Extract of Sarsaparilla. 

Contains sarsaparilla, liquorice root, sassafras, and 
mezereum. 

Dose, 3 i. (4- gm-) 

Aloe Barbadensis and Aloe Socotrina. 
Barbadoes and Socotrine Aloes. 

The thickened juice of the leaves of Aloe socotrina, 
from an island in the Indian Ocean, and Arabia. It has 



I96 MATERIA ME DIC A FOR NURSES. 

a very nauseous and bitter taste, and contains an active 
principle, aloin, which has cathartic qualities. 

Aloes is a bitter Stomachic, and as a cathartic acts 
principally on the colon, and with extreme slowness ; 
ten or fifteen hours being required for a result if it is 
given alone. It stimulates the flow of bile to some ex- 
tent, and excites the circulation of all the pelvic organs 
Aloes is rarely used alone, but is an ingredient of many 
well-known laxative preparations in liquid and in pill 
form, usually in strength of 2 or 3 grains. It does not 
cause constipation as an after-effect, but on the contrary, 
makes the intestines more sensitive. 
Tinctura Aloes. 
Tincture of Aloes. 

Strength, § ss.-Oj. Dose, 3 i.-iii. (4.-12. gm.) 
Tinctura Aloes et Myrrhae. 
Tincture of Aloes and Myrrh. 

Strength, § iss. of each in Oj. Dose, 3 i.-ii. (4.-8. gm.) 
Pilulae Aloes et Mastiches. 
Lady Webster's Dinner Pills. 

Each contains 2 grains of aloes. 

Nat. Ord. Labiatcz. 
Convallaria (Lily of the Valley). 

The entire plant of the Convallaria majalis, the lily of 
the valley. It contains two glucosides : one, convallarin, 
is crystalline, and has special qualities as a gastrointes- 
tinal irritant ; and the other, convallamarin, is amor- 
phous, and acts as a stimulant to the circulation. 

Physiological Actions. 

Convallaria slows and strengthens the heart, and 
raises the blood pressure ; makes the respirations a little 
more full and less frequent than ordinary, and is a very 
decided diuretic. In excessive doses the heart is dis- 
turbed and the pulse becomes irregular ; the breathing 
is forced ; deep and prolonged inspiration being pro- 
duced by spasm of the inspiratory muscles. 



THE VEGETABLE KINGDOM. iqj 

When a poisonous quantity is taken, arterial pressure 
rises very high, and the pulse is correspondingly rapid, 
until shortly before death, when the pressure falls, respi- 
ration grows slow and deep, and the heart stops in sys- 
tole. Convallaria does not affect the brain. 

Preparations. 

Extractum Convallariae. 

Dose, gr. v.-xv. (0.3-1. gm.) 
Extractum Convallariae Fluidum. 

Dose, TT[ ii.-x. (til x. — gtt. xxv.). (0.1-0.65 g m -) 
Convallarinum. 
Convallarin. 

Dose, gr. ss.-ii. (0.03-0.13 gm.) 

Nat. Ord. Phytolaccacecz. 

Phytolacca (Poke). 

The berry and root of Phytolacca decandra. Phyto- 
lacca is depressing to the heart and respirations, and is 
to some extent narcotic. It is an alterative, and pro- 
motes absorption of fatty tissue. "Anti-fat" remedies 
sometimes contain phytolacca. It is useful as a local 
medicament, and is used in various skin disorders. 

The dose of the fluid extract is TT{, v.-xxx. (0.3-2. gm.) 

Nat. Ord. Melanthacea. 

Veratrum Viride. 
Indian Poke ; American Hellebore. 

The dried root-stock of Veratrum viride, a plant be- 
longing to the Northern States of the United States. It 
yields two alkaloids, jervine and veratroidine. 

Physiological Actions. 

Veratrum viride is a powerful cardiac depressant. 
When taken in small doses the pulse is at first reduced 



I98 MATERIA MEDIC A EOR NURSES. 

in strength and later in frequency, being sometimes 
lowered to 35 or 40 a minute. The fall of the pulse is in 
constant proportion to dose taken. It is then soft, com- 
pressible, and may be moderately full, but any exertion 
may change its character and it becomes rapid, thready, 
small, and weak, being at times almost imperceptible. 
Nausea and vomiting may also be produced at this 
stage, with excessive muscular depression and weakness. 
The depressing action on the heart is the result of direct 
influence over the heart muscle, and also over the 
inhibitory apparatus. The brain is not affected. 

Symptoms of Poisoning. 

Excessive doses of veratrum viride produce violent 
and alarming symptoms, but fatal results from it are 
rare, as vomiting is usually set up immediately. The 
nausea is intense and the emesis violent ; the skin cold 
and clammy and the pulse thread-like. 

Hiccough, faintness, and vertigo, partial unconscious- 
ness, and loss of sight may be noticed among the symp- 
toms of poisoning. Recovery has taken place after a 
teaspoonful dose of the fluid extract, and, in another 
case, the same amount caused death. 

Treatment of Poisoning. 

Emesis must be encouraged, and the stomach well 
washed out with warm water. The patient should not 
be allowed to rise during the act of vomiting, but to turn 
to the side, and afterwards, lying on his back, with the 
feet higher than the head, must maintain perfect rest. 

Alcoholic stimulants are used, and external heat is of 
importance, with gentle friction to excite the capillary 
circulation. 

Incide?ital Effects. 

The action of the skin is increased in an indirect way 
by veratrum viride, and the secretion of bile is also stim- 
ulated. The temperature is quite markedly lowered by 
full doses, and various incidental effects, such as a feel- 
ing of heat and prickling, restlessness, anxiety, dizziness, 



THE VEGETABLE KINGDOM. 1 99 

dimness of vision, unsteady gait, a dryness of the mouth, 
with thirst, choking, nausea, and vomiting, may appear 
after medicinal doses. 

An eruption attended with itching is sometimes pro- 
duced, appearing on the face and especially round the 
mouth. With suspension of the drug this soon dis- 
appears. 

In giving veratrum, if no special orders about the 
pulse have been given, it should not be allowed to fall 
below 70. A fall below 55 is dangerous. 

Preparations. 

Tinctura Veratri Viridis. 
Tincture of Veratrum Viride. 

Strength, 50 </ . Dose, TH, iii.-vi. {V\, x. = gtt. xxv.). 
(0.2-0.4 gm.)' 
Extractum Veratri Viridis Fluidum. 

Dose, 1U i.-iii. (TT|, i. = gtt. ii.). (0.06-0.2 gm.) 
Norwood's Tincture is a saturated tincture and is unofficial. 

Veratrina (Veratrine). 

A compound of alkaloids contained in the seed of 
Asagrcea officinalis. 

It is exceedingly poisonous, and is little used internally. 
Poisonous doses cause convulsions and tetanus, with 
death from asphyxia. Externally it is irritant, causing 
prickling and tingling, redness of the skin, numbness, 
and vesication. The unguent is a powerful counter- 
irritant, but needs to be used with care, special pains 
being taken not to get it near the eyes, as it may cause 
violent irritation of the conjunctivae. 

The official ointment usually requires dilution. 

Preparations. 

Unguentum Veratrinae. 

Strength, 4 <f . 



200 MATERIA MEDICA FOR NURSES. 

Ointment of Veratrine. 

For external use. 

Oleatum Veratrinae. 
Oleate of Veratrine. 

Strength, 2 <f>. For external use. 

Colchici Semen (Colchicum Seed). 

Colchici Radix (Colchicum Root). 

Meadow Saffron. 

The dried ripe seeds and corm * of Colchicum autum- 
nale, found in Europe. The active principle is called 
colchicine. 

Physiological Actions. 

Colchicum is a sedative to the central nervous sys- 
tem ; a diuretic ; and an irritant cathartic. It stim- 
ulates the liver, and excites the action of the skin. The 
urine, urea, and uric acid are increased in amount by 
moderate doses of colchicum. The pulse is slightly re- 
duced in frequency — about 12 beats less to the minute 
being noticed while the impression lasts. 

Symptoms of Poisoning. 

Colchicum in poisonous doses is an acro-narcotic, 2 
producing a combination of nervous and gastro-intestinal 
symptoms. 

Nausea, violent and persistent vomiting and retching 
appear first, with purging of serous, mucous, and bloody 
matters, attended with griping pain. 

1 A part of the stem which is underground, yet not the actual root 
— a bulb. 

2 A poison which is irritant, and which also acts on the brain and 
spinal cord. 



THE VEGETABLE KINGDOM. 201 

Tenderness and burning are felt in the abdomen and 
stomach ; the urine may be diminished or suppressed, 
while in some cases it is increased, and in others the 
kidneys seem unaffected almost to the last. 

Spasms occur frequently, and there may be fatal con- 
vulsions. The circulation fails, the pulse becomes rapid 
and grows feeble and thready, the skin is cold, livid, and 
covered with perspiration. 

Consciousness remains, and death results from col- 
lapse. 

The fatal dose is small, death having been caused by 
3 ii.-ss. of the wine. 

Treatment of Poisoning. 

The only chemical antidote is tannin, though it is not 
always sure in its action. Emetics, with plenty of warm 
water, and castor oil must be given ; albuminous drinks 
— milk, white of egg, etc. — and demulcents freely given, 
and stimulation used as the need arises. 

Incidental Effects. 

Colchicum, even in small doses, may produce un- 
pleasant secondary symptoms : dizziness, fulness and 
pain in the head ; pains over the body ; numbness, red- 
ness, prickling or smarting sensations ; sneezing ; running 
at the eyes ; irritated fauces ; coated tongue ; loss of 
appetite or nausea ; abdominal uneasiness or pain ; 
flatulence or borborygmi ; or rectal tenesmus may be 
observed. 



Preparations of Colchicum. 

Tinctura Colchici Seminis. 
Tincture of Colchicum Seeds. 

Strength, seeds, 15 parts in 100. Dose, 3 ss.-iss. 
(2-6. gm.) 



202 MATERIA MEDICA FOR NURSES. 

Vinum Colchici Seminis. 
Wine of Colchicum Seeds. 

Same strength. Dose, 3 ss.-iss. (2.-6. gm.) 

Extractum Colchici Seminis Fluidum. 
Fluid Extract Colchicum Seeds. 

Dose, TT[ ii.-vi. (t\[ x. = gtt. xxv.). (0.1-0.35 g m -) 

Vinum Colchici Radicis. 
Wine of Colchicum Root. 

Strength, 40 f . 

Dose, TT|, x.-xv. (TT[ x. = gtt. xx.). (0.6-0.1 gm.) 

Purgative dose, 3 ss. 

Extractum Colchici Radicis Fluidum. 
Fluid Extract of Colchicum Root. 

Dose, Tli ii.-iv. (fT[ i. = gtt. ii.). (0.1-0.3 g m -) 

Nat. Ord. Graminacece. 
Ergota (Ergot). 

Ergot is a parasite which developes in rye, taking the 
place of the grain, and having the appearance of a black- 
ish fungus. It is a complex substance, containing various 
alkaloids and acids ; a fixed oil, etc. 

Three of the alkaloids are named ecboline, ergotine, 
and ergotinum ; and the watery extract ergotin contains 
all the important constituents, and may be considered to 
represent the active principles of ergot. 

Physiological actions. 

Ergot is specially known as an oxytocic, exciting or 
increasing uterine contractions ; and as a haemostatic. 

In the latter capacity it acts by contracting the small 
vessels, thus promoting coagulation. The frequency of 
the pulse is lessened by ergot, and very large doses 



THE VEGETABLE KINGDOM. 203 

depress the heart and vaso-motor centres and lower 
arterial pressure. 

It is not an active poison, and an ounce of the fluid 
extract has been given without producing serious symp- 
toms. 

Symptoms of Poisoning. 

In cases where poisoning has occurred the symptoms 
were thirst ; gastric irritation and diarrhoea ; a small 
pulse ; burning pain in the feet ; and sometimes tingling 
and cramps, dizziness, dilated pupils, and a feeling 
of cold. Before death there are convulsions. In Euro- 
pean countries, where the poorer classes live largely on 
rye bread, chronic ergot-poisoning is familiar, and has at 
times prevailed as a scourge. There are two varieties of 
this chronic poisoning — the gangrenous and the spas- 
modic, — but it is unknown in this country, and need not 
be described here. 

Incidental Effects. 

The urine, perspiration, and milk are reduced in quan- 
tity by ergot. After taking medicinal doses, one or more 
of the following symptoms may be observed : an un- 
pleasant taste in the mouth ; tickling in the throat ; 
nausea ; burning pain in the stomach or abdomen, with 
eructations of gas or diarrhoea ; headache ; lassitude ; 
giddiness ; specks before the eyes ; unsteady gait ; 
irregular pulse ; chilly feelings. 

Extractum Ergotae Fluidum. 
Fluid Extract of Ergot. 

Dose, 3 i.-ii. (4.-8. gm.) 
Ergotin. 

Bonjean's preparation of ergotin is about ten or twelve 
times as strong as ergot — gr. v. or vi. representing 3 i. of 
the drug. It is used hypodermically. 

It is irritant to the tissues and may produce abscesses, 
even when deeply given. 

Preparations of ergot lose their strength if kept for 
any length of time. 



204 MATERIA MEDICA FOR NURSES. 

Nat. Ord. Filices. 
Aspidium ; Filix Mas (Male Fern). 

The root-stock of Aspidium filix mas, an European 
fern. The medicinal principle of fern is an oleo-resin of 
a bitter, nauseous taste. 

It is an anthelmintic, specially destructive to the 
tape-worm. Although less irritating than some others 
of its class, it may, in overdoses, produce severe intesti- 
nal irritation, and death has been caused in an adult by 
taking six ounces. 

Nat. Ord Fungi. 
Agaricus. 

A fungus, called polyporus officinalis, white or purging 
agaric, which grows on the larch. 

In small doses it checks perspiration, the secretions of 
the bronchial tubes, the mammary glands, and the bowels. 
In large doses it is purgative. 
Agaricin. 

Dose, gr. -£-£, in pill. (0.01-0.03 gm.) 

Nat. Ord. Lycopodiacece. 

Lycopodium. 

The dust, or sporules, which fills the spikes of a 
European moss. Collected in Switzerland and Ger- 
many, and used as a dusting powder for infants especially; 
also for bed-sores, etc., either alone or mixed with bis- 
muth. Locopodium is inflammable, and is sometimes 
called vegetable sulphur. It is a very soft, fine powder, 
and is used in rolling and packing pills and suppositories. 

THE ANIMAL KINGDOM. 
Lanolin. 

A combination of fats obtained from sheep's wool. It 
does not become rancid, nor form soaps, and is rapidly 
absorbed by the skin. 

It is used as a simple emollient, and as a means of 
introducing medicine into the system. 



THE ANIMAL KINGDOM. 20$ 

Saccharum Lactis (Sugar of Milk). 

A crystallized sugar obtained by evaporation from the 
whey of milk, and specially suitable for use in preparing 
baby foods. It is soluble in one part boiling and seven 
parts cold water. 

Pepsin. 

Pepsin is one of the normal constituents of the 
gastric juice, and, with the aid of hydrochloric acid, 
changes albumins into peptones, in which form they are 
readily diffusible and capable of being absorbed into 
the blood. 

Pepsin, as used in medicine, is a preparation made 
from the mucous membrane which lines the stomach of 
the calf, sheep, or pig. 

It is made by cleaning the mucous lining, scraping it, 
drying the pulp at a temperature of ioo° F., and pulver- 
izing it. The powder is a light yellow-brown, almost 
insoluble in water, and of slightly salty taste. It may be 
taken dry on the tongue or given in milk. 

Dose, gr. ii.-v., with meals or immediately after. 
(0.13-0.3 gm.) 

Pancreatin. 

A preparation made from the pancreas of the pig. 
Pancreatic extract digests starchy and proteid sub- 
stances, and pancreatin, while not given alone as a 
medicine, is very largely used in preparing artificially 
digested foods, viz. : pancreatized milk, eggs, oysters, 
soups, broths, etc. 

The principle followed in making pancreatized food 
is that by subjecting it to the action of pancreatin in the 
presence of moderate heat, the process of digestion takes 
place, and may be made complete or only partly so, 
according to the length of time during which they are in 
contact. 



206 MATERIA MEDIC A FOR NURSES. 

The digestive process is stopped by heat at the boiling 
point, or by extreme cold. For this reason artificially 
digested foods, having reached the point desired, are 
either brought quickly to a boil or else are put on ice. 

Milk, if thoroughly digested, has a slightly bitter taste, 
which is not noticeable if the process has been short of 
complete. 

Adeps Praeparatus (Prepared Lard). 

Lard consists of a fluid oil, olein, with stearin and 
palmitin, which are solid oils. 

It is used as the basis of various officinal ointments. 

Benzoinated Lard. 

One part of benzoin to fifty parts of lard. 

Cetaceum Spermaceti. 

A fatty substance obtained from the head of the sperm 
whale, and resembling white wax. 
It is used as an emollient. 

Oleum Morrhuse (Cod-Liver Oil). 

The oil obtained from the liver of gadus morrhua, and 
other species of cod fish. An exceedingly complex sub- 
stance, containing glycerine, acetic acid, and several 
fatty acids, iodine, chlorine, and traces of bromine, 
phosphorus and phosphoric acid, and various other con- 
stituents. There are three varieties : the pale yellow, 
light brown, and dark. The pale oil is the purest, being 
prepared by forcing steam at high pressure through the 
livers, and is less nauseous than the dark oil. 

Physiological Actions. 

Cod-liver oil is an alterative to the general nutrition 
in various diseased conditions, and is more truly a food 



THE ANIMAL KINGDOM. 207 

than a medicine, as it supplies the need of the tissues for 
fat. Fat produces force, and is utilized by every part of 
the body in quantities directly proportioned to the 
activity of the different tissues. The nervous system 
needs the largest amount ; the muscular, the next largest. 
Having been elaborated by the liver of the fish, cod-liver 
oil is more easily digested than other fats. 

The smell of cod-liver oil is unpleasant and sometimes 
causes nausea. This may be avoided by taking some 
peppermint into the mouth just before taking the oil, 
and by avoiding bringing it into direct line with the 
nose. All patients do not know how to take oil ; by 
tossing it into the mouth and not allowing the lips to 
touch it, it is less disagreeable. 

It is best to mix no other medicines with cod-liver oil, 
except hypophosphites. If other medicines come at the 
same time they should be given separately. It may be 
given in any of the ways in which castor oil is given ; it 
is almost always well taken if floated in a little brandy or 
wine, or lemon juice. These precautions about giving it 
do not necessarily apply to" the various emulsions of oil, 
which are usually not at all hard to take. The proper 
time to administer cod-liver oil is when digestion is at its 
height. 

In overdoses, or when first taken, it may disorder the 
stomach, or cause temporary relaxation of the bowels. 
It sometimes causes an eczema. 

Emulsions of cod-liver oil spoil in a short time, and 
patients should not be encouraged to buy the ready- 
made preparations in the shops. 

In giving cod-liver oil the faeces must be watched, to 
see if any is carried away undigested. 

Dose, 3 i.- 1 ss., from three quarters of an hour to an 
hour after meals. (4.-16. gm.) 

Cantharis (Cantharides ; Spanish Flies). 

The dried and powdered bodies of the cantharis vesi- 
catoria, a beetle of Southern Europe. The powder is 
grayish-brown and specked with minute greenish span- 



2o8 MATERIA MEDIC A FOR NURSES. 

gles from the wing-cases of heads. It has a strong 
unpleasant odor. The active principle is cantharidin, 
an active irritant, besides which it contains a volatile 
oil and fatty substances. 

Physiological Actions. 

Externally cantharides is vesicant. When applied to 
the skin a feeling of heat and burning is felt in a few 
hours, and small vesicles form which unite in one large 
blister. 

The average time required for this result is about 
eight hours. The action of cantharides is attended with 
less injury to the skin than that of any other vesicant. 
No pus is formed during the healing process, and no scar 
is left by the blister. 

Internally cantharides is irritant to mucous mem- 
brane, and if given medicinally must be largely diluted. 
It enters the blood from the stomach and also from 
blistered surfaces, and is slowly excreted by the kidneys. 
In small doses it causes diuresis with some irritation of 
the urinary organs, and larger doses produce strangury. 

Symptoms of Poisoning. 

When a poisonous dose of cantharides is taken the 
first symptoms are burning in the oesophagus and stom- 
ach, a constricted feeling about the throat, gastric and 
abdominal pain, with vomiting and in most cases 
diarrhoea. 

If the powder has been taken the small green specks 
may be seen in the matter vomited, which is at first 
mucous, then bilious, and finally serous. The discharges 
from the bowels have the same characteristics and are 
scanty, frequent, and accompanied by tenesmus. There 
is frequently salivation with swelling of the salivary 
glands. The pulse is weak and rapid, and death usually 
occurs quickly from collapse caused by the gastrointes- 
tinal inflammation, but if it is delayed for a few hours the 
symptoms of irritation of the urinary apparatus appear, 



THE ANIMAL KINGDOM. 20Q 

beginning with pains in the back, and ending in stran- 
gury, with scanty, albuminous, or bloody urine, and 
tenesmus of the bladder. 

Treatment of Poisoning. 

There is no antidote to cantharides, and the stomach 
must be at once emptied, and as thoroughly as possible 
washed out ; large quantities of albuminous and mucila- 
ginous drinks given ; warm baths to relieve the strangury, 
and stimulant? 'f necessary. No oils or glycerine must 
be given, as they aid in the absorption of the poison. 

It is to be remembered that constitutional effects are 
sometimes produced by even a moderate blister, and if 
necessary, the blister must be removed and the part 
washed with soap and water. 

Cautions. 

Before applying a blister the spot should be washed 
with soap and water ; dried ; washed again with alcohol 
or ether, and briskly rubbed for a moment or two. 
Absorption then takes place more quickly. A blister 
should never be applied over a bony prominence, as 
sloughing may follow, the circulation in such parts being 
sluggish. On tender skins vesication is soon produced 
and the blister must be carefully watched lest the action 
be too severe. On coarse skins, or in places where it is 
thick, as on the scalp or at the knee-joint, more time is 
needed. 

Hairs must be cut away, or shaved. A blister should 
not be left on a child's skin long enough to rise, but 
should be rejnoved when redness appears, and poultices 
be applied to finish the process. 



MISCELLANEOUS LIST OF NEW DRUGS 
ARRANGED ALPHABETICALLY. 



Acetal. 

A derivative of alcohol, employed as a sedative and 
hypnotic. It is usually given as an emulsion. 
Dose, gr. 75-150. (5.-10. gm.) 

Agathin. 

Agathin is obtained from the salicylates, and is used 
as an anti-neuralgic and anti-rheumatic. 
Dose, gr. ii.-viii. (0.12-0.5 S m «) 

Analgen. 

A remedy used as an anti-neuralgic, antipyretic, and 
analgesic, and considered efficient. 

Dose, gr. x.-xv. (0.65-1. gm.), repeated in three hours. 

Antinervin. 

This drug contains ammonium bromide, salicylic acid, 
and acetanilid. It is used as an anodyne and anti- 
neuralgic. 

Dose, gr. xv. (1. gm.) 

Antisepsin. 

This is also called asepsin. It is produced from bro- 
mine and acetanilid. It is soluble in alcohol and ether. 



212 MATERIA MEDIC A FOR NURSES. 

but insoluble in water. It is used as an antipyretic, 
analgesic, and antiseptic. Unpleasant symptoms that 
may be caused by it are cyanosis, a depressed pulse, and 
tremors. 

Dose, gr. \-\. (0.03-0.06 gm.) 

Antiseptol. 

Antiseptol is a reddish-brown powder made from 
iodine and cinchonine, and used as a substitute for 
iodoform. 

Antispasmin. 

A combination of narcein, sodium, and salicylate of 
sodium. It is a whitish powder, and absorbs water from 
the air. It is soluble in water. It is used as a sedative 
and hypnotic, and given usually in syrup. 

Dose, gr. \- \\. (0.01-0.10 gm.) 

Apolysin. 

Apolysin resembles phenacetine in its actions, lowering 
fever, and diminishing pain and hyperesthesia. It is 
used as an anti-neuralgic. It is readily absorbed and 
acts quickly. It is not poisonous, and there are usually 
no unpleasant after-effects. It should not be given on 
an empty stomach. 

Dose, gr. v.-xxx. (0.3-2. gm.) 

Aristol (Annidalin). 

The essential constituent of aristol is iodine, of which 
it contains about 45 $., other substances entering into its 
composition being thymol and sodium. It is odorless, 
and is used as a substitute for iodoform. As an antisep- 
tic it is not strong and has no poisonous qualities. It is 
used in dusting powders, ointments, and solutions in oil, 
ether, or collodion, usually in a strength of from 5-10 <f . 

Asaprol. 

Asaprol has analgesic properties. It also checks 



MISCELLANEOUS LIST OF NEW DRUGS. 213 

hemorrhage, lowers temperature, and lessens nervousness 
and insomnia. It increases the amount of urine, and 
sometimes gives rise to profuse perspiration. Internally 
from gr. v.-xl. (0.3-2.65 gm.) may be given in a day. It 
is soluble in water and in alcohol, and is incompatible 
with quinine, iodide of potassium, and the soluble sul- 
phates. For lotions or irrigation it is prepared in a 
strength of 1-5 f . 

Benzosol. 

This is a compound of guaiacol. A colorless, inodor- 
ous, tasteless powder, insoluble in water. It contains 
about 50 </ of guaiacol. It is used as an antiseptic in 
the treatment of phthisis. 

Dose, gr. iv.-viii. (0.25-0.5 gm.) 

Betol or Naphtalol. 

A compound analogous to salol, but containing 10 $ 
less of salicylic acid, and being correspondingly less 
active and less effective. In the intestines it decom- 
poses into naphthol and salicylic acid. It is used in the 
same way as salol. It is best given in pill or emulsion. 

Dose, gr. ii.-v. (0.15-0.3 gm.) 

Bromal Hydrate. 

Made by the action of bromine on alcohol. It is sim- 
ilar to chloral hydrate in its actions, being antispasmodic 
and hypnotic, but is more powerful than chloral and 
more direct and dangerous in its influence over cardiac 
muscle. Large quantities may cause death, preceded by 
anaesthesia and convulsions. 

Dose, gr. ii.-v. (0.12-0.3 g m -) 

Bromoform. 

An analogue of chloroform, made from methylic alco- 
hol and caustic potash. It is soluble in alcohol ; only 
slightly so in water. It is quite powerful in its actions, 



214 MATERIA MEDIC A FOR NURSES. 

which are antispasmodic, analgesic, and antiseptic. It 
has been used with success in whooping cough. 
Dose, TT[ i.-v. (0.06-0.30 gm.) 

Carvacrol. 

A phenol which is contained in the essential oil of the 
origanum species. A thick, oily fluid, used as a local 
disinfectant in treating wounds, ulcers, and skin diseases. 
It is strongly antiseptic. 

Creolin. 

Creolin is an emulsion of cresol, a derivative of car- 
bolic acid. It mixes in all proportions with chloroform, 
ether, and alcohol, and with water forms a milky solu- 
tion. It is claimed that creolin is germicidal but not 
poisonous. It is used locally in a variety of ways : as 
an ointment, in a strength of 5 </ ; in solution, 1 </ , or 
one half of one, for douches or vesical irrigation, etc. 
For surgical dressings creolin gauze is made in a strength 
of 5-10 </o. 

Dermatol (Bismuth Subgallate). 

Dermatol contains about 55 <f of the oxide of bismuth. 
It is a yellow, odorless powder, insoluble. It is an ex- 
cellent antiseptic, used in place of iodoform. It is also 
successfully used internally in some diseases of the ali- 
mentary canal. 

Dose, by mouth, gr. xxx. (2. gm.) 

Locally it is used as a powder, in gauze, emulsion, or 
ointment. Strength, 10-20 $. 

Diphtheria Antitoxin. 

The antitoxin used in the treatment of diphtheria is 
the blood-serum of animals which has been immunized 
by the injection of the diphtheria toxine. To prepare it 
the bacilli of diphtheria are cultivated under favorable 



MISCELLANEOUS LIST OF NEW DRUGS. 21$ 

conditions, and, as they grow, their peculiar poison or 
toxine is formed. When sufficient has been produced it 
is separated from the bacilli, which are previously killed, 
and a small portion is injected into the blood of a 
healthy horse, producing a slight attack of diphtheria. 
This proceeding is repeated for several months until the 
horse is habituated to the poison. The blood-serum of 
the horse then contains the antitoxine. A quantity of 
blood is drawn from the horse and the serum carefully 
separated. There are several preparations : Behring's, 
Gibier's, Roux's, and Schering-Aronson's. The anti- 
toxine is used hypodermically, and the amount given 
varies from 5-15CC 

Eucaine. 

Eucaine may be used as a local anaesthetic in strength 
of ^ of 1 io in place of cocaine, but is less satisfactory. 
It is irritant and must be used with care. 

Europhen. 

A powder containing about 27 <f> of iodine, and used 
as a substitute for iodoform. It is soluble in alcohol, 
ether, chloroform, and oil. As a dusting powder it is 
used in a strength of from 5-10 $, and hypodermically 
solutions in olive oil are used in from 3-10 </ strength. 

Haemogallol. 

Haemogallol is obtained by oxydizing the haemoglobin 
of the blood by the action of pyrogallol (a derivative of 
gallic acid). It is a reddish-brown powder, easily assim- 
ilated, and is used in chlorosis and anaemia. It is insol- 
uble in water, and is given in tablets or in wine. 

Dose, gr. iii.-viii. (0.2-0.5 gm.) 

Haemoglobin. 

The red coloring matter of the blood corpuscles. It 



2l6 MATERIA MEDICA FOR NURSES. 

forms a red powder, soluble in water. It has been used 
in the treatment of anaemia and chlorosis. 
Dose, gr. iss.-iii. (0.09-0.18 gm.) 

Hypnal. 

A combination of antipyrin and chloral. Its action is 
hypnotic and analgesic. It is soluble in water. 
Dose, gr. xv.-xxx. (1.-3. gm.) 

Izal. 

A disinfectant produced in making coke. It is said to 
have some advantages over carbolic acid. It does not 
hurt instruments, and may be used internally, externally, 
and hypodermically. It is used in a strength of 1 or -§-$. 

Kola. 

Kola contains the alkaloids theobromine and caffeine, 
and a principle known as kolanin. It is used internally 
as an astringent. It lessens tissue waste, is a tonic stim- 
ulant to the circulation, and aids the alcoholic subject in 
resisting the craving for liquor. 

Loretin. 

A yellow, crystalline, odorless powder. It is con- 
sidered a good antiseptic and deodorant. It is used as 
a dusting powder T also as an ointment, strength 5-10 $ ; 
combined with collodion, strength 2-10 f ; and in pen- 
cils of cocoa butter, 5-10 #. 

Losophan. 

Losophan is a preparation containing about 78 </ of 
iodine. It is used in powder, ointment, and solution, in 
from 10-20 <f 0y in the treatment. of skin diseases. 



MISCELLANEOUS LIST OF NEW DRUGS. 2\J 

Lycetol. 

A diuretic. 

Dose, gr. xv.-xxx. (1.-2. gm.), dissolved in water. 

Lysol. 

A derivative of carbolic acid, containing 50 <f of cre- 
sols. It forms a soapy liquid with water, and combines 
with alcohol and glycerine. It is used as a disinfectant 
for the skin, in 1 % solution, and for wounds and abscesses 
in from 1-3 f . 

Malakin. 

A mild antipyretic and anodyne. It acts slowly and 
gently, and has no unpleasant effect on the stomach. 
Neither does it produce cerebral symptoms. It some- 
times, but not always, causes sweating. 

Dose, gr. xv.-lxv. (1.-4.3 gm.) per day, in capsules. 

Methacetin. 

A compound analogous to phenacetin. It is tasteless 
and colorless, soluble in alcohol, glycerin, and oil ; also 
slightly soluble in water. It has been used as an anti- 
septic, analgesic, and antipyretic, and has been some- 
what popular in the treatment of fevers in children. It 
is rather depressing, and has sometimes caused collapse. 
Large doses may bring on convulsions, followed by death. 

Dose, gr. ii.-v. (0.12-0.3 gm.) 

Methylal. 

A local anaesthetic and hypnotic, derived from alco- 
hol. It is soluble in water and alcohol, and has an aro- 
matic odor and taste. The sleep produced by it is sound 
but of short duration. It is depressing in large doses. 
It has been used in cases of insanity and delirium tremens. 

Dose, TT[ v. (0.3 gm.), repeated once or twice. 



2i8 MATERIA MEDIC A FOR NURSES. 

Methylene Blue. 

Methylene Blue is one of the " aniline dyes." It is 
slightly soluble in water. It is a bluish powder, and has 
been largely used in treating rheumatic and neuralgic 
disorders, and in phthisis. It is also considered a good 
antiperiodic. It is given in wafers or capsules, and hypo- 
dermically. 

Dose, gr. iss.-viii. (0.09-0.52 gm). 

Microcidin. 

This is a compound of naphthol with sodium hydrate. 
It is soluble in water, and is used as an antiseptic in so- 
lutions of from 1-5 <f . 

Migranin. 

An antipyrin preparation containing antipyrin, caffeine, 
and citric acid. It is used in the treatment of migraine 
and influenza. 

Dose, gr. xv. (1. gm.) 

Orexin. 

Orexin is a derivative of chinolin. It is a gray powder, 
of bitter taste, soluble in water and alcohol. It is used 
as an appetizer and stomachic tonic, but is somewhat ir- 
ritating, and should not be given on an empty stomach. 

Dose, gr. iii. (0.2 gm.), in capsule, at meal-time, or ac- 
companied by food or some nourishing drink. 

Phenosalyl. 

A solution of carbolic, salicylic, and benzoic acids in 
lactic acid. It is used externally as an antiseptic, being 
considered superior to carbolic acid and less poisonous. 
It is a thick syrup liquid, soluble in cold water in a 
strength of 7 $. It is used in solutions of 1 ^ and 2 $. 



MISCELLANEOUS LIST OF NEW DRUGS. 219 

Piperazine. 

A drug formed by the action of ammonia upon ethylene 
bromide. It is used as a diuretic, its active properties 
arising from its capacity for dissolving uric acid. This 
solvent power is much greater than that of other drugs 
known. Gouty deposits are said to be neutralized and 
dissolved by piperazine. 

Dose, gr. v.-x. (0.3-0.65 gm.), in carbonated water. 

Salipyrin. 

This drug is the salicylate of antipyrin. It is con- 
sidered an efficient antipyretic, and is also used in sci- 
atica and rheumatism, influenza, and the dysmenorrhoea 
accompanying the menopause. 

Dose, gr. xv. (1. gm.), and this may be repeated several 
times. 

Salophen. 

A derivative of salol, introduced as a substitute for the 
latter in order to avoid effects arising from the liberation 
of phenol in the organism, which occurs when salol is 
used. Its physiological actions are similar to those of 
salol. 

Dose, gr. viii. (0.5 gm.) 

Somnal. 

Somnal is made by the combination of chloral, alcohol, 
and urethan. It is a colorless liquid which will not mix 
with cold water, but dissolves in alcohol or hot water. 
It is quite an efficient hypnotic, and usually prompt in its 
action. Its effects are considered less depressing than 
those of chloral, and more active than those of urethan. 

Dose, Til, xv.-xxx. (1.-2. gm.), taken in syrup or 
whisky. 

Sozoiodol. 

This drug contains iodine, about 50 $, and sulphur, 7 $. 



220 MATERIA MEDICA FOR NURSES. 

It is soluble in alcohol, glycerin, and water. It is used 
as an antiseptic powder in a strength of from 5-20 $. 

Stypticin. 

Stypticin is obtained from narcotin, one of the alka- 
loids of opium, and may be used as a styptic in gyneco- 
logical cases. It is given in solution, or in powder, 
wrapped in wafers, or best, in gelatine pearls. It may 
also be used hypodermically. 

Dose, gr. -f-i. (0.025-0.06 gin.) repeated frequently. 

Terebenum (Terebene). 

A colorless liquid, of hot taste, obtained by chemical 
process from oil of turpentine. It is used as a stimulant 
expectorant. 

Dose, gr. v.-xx. (0.3-1.3 gm.), in an emulsion or in 
capsule. 

Terpin Hydrate. 

Made from turpentine and nitric acid. It is used as 
an expectorant in bronchitis, whooping cough, and 
chronic nephritis 

Dose, gr. iii.-vi. (0.2-0.4 g m -) given in tablets or syrup. 

Terpinol. 

An oily liquid, obtained by combining terpine and 
hydrochloric acid. It has the same stimulant and expec- 
torant properties as terpin hydrate, and is used under 
similar circumstances. 

Dose, Tlj, x.-xv. (0.6-1. gm.), given in capsule or pill. 

Tetronal. 

A compound allied to sulfonal, and in all points simi- 
lar to trional. 

Dose, gr. x.-xx. (0.65-1.3 gm.) 



MISCELLANEOUS LIST OE NEW DRUGS. 221 

Thymacetin. 

A derivative of thymol, and related to phenacetin. It 
is used as an analgesic and hypnotic in nervous cases. 
The after-effects are sometimes unpleasant. 

Dose, gr. iii.-xv. (0.25-1. gm.) 

Trional. 

Trional is chemically allied to sulfonal, and is given 
as a hypnotic in nervous cases, and also as an antihydro- 
tic in night sweats. When it is successfully given it pro- 
duces a quiet sleep and a natural awakening, but if, after 
being given twice in succession no results follow, it is 
useless to try it further. When it acts it acts quickly, 
and sleep comes on within a short time. It should not 
be given for more than five or six nights in succession, 
as it sometimes causes prostration. It is apt to accumu- 
late in the blood, and to avoid this, mineral waters are 
taken in conjunction with it. It causes constipation, 
and this must be watched for and overcome. It is given 
in hot milk just before retiring. 

Dose, gr. xv.-xxx. (1.-2. gm.) 

Tuberculin. 

The extract known as " Koch's lymph " is obtained 
from pure cultures of the tubercle bacillus. Its chemi- 
cal nature is not precisely known. It is used hypoder- 
mically, the dose at the beginning of treatment being 
usually gr. -%\-§-^\-§ (0.0003-0.0005 gm.), and gradually 
increased. 

Uricedin. 

A diuretic, which may be given in doses as large as 
gr. 150 daily without bad results. It may, however, in 
such doses act as a purgative, though not to an unpleas- 
ant or painful degree. 



222 MATERIA MEDIC A FOR NURSES. 

Urotropin. 

A diuretic, given usually in a large single dose in the 
morning. It dissolves uric acid calculi, and may be 
given in amount as large as 90 grains (6. gm.) daily 
without bad results. 



APPENDIX. 



RELATION OF MINIMS TO DROPS IN 
CERTAIN MEDICINAL LIQUIDS 

(see note at end.) 

Acetum Opii ttj, 10 = gtt. 15 

Acidum Aceticum TT|, 10 = gtt. 18 

Dilutum . . . . HI 10 = gtt. 10 

" Carbolicum Liquefactum . . . TTJ, 10 = gtt. 18 

" Hydrochloricum til 10 = gtt. 10 

" " Dilutum . . . in, 10 = gtt. 10 

" Hydrocyanicum " . . TT[ 10 = gtt. 10 

" Nitricum tq, 10 = gtt. 17 

" " Dilutum . . . .. 1T1 10 = gtt. 10 

Nitrohydrochlor. Dilutum . . . itl 10 = gtt. 10 

" Phosphoricum " . . TTJ, 10 = gtt. 10 

" Sulphuricum Aromaticum . . TT|, 10 = gtt. 24 

" " Dilutum . . . . TU 10 = gtt. 10 

<Ether Fortior m 10 = gtt. 30 

Alcohol ttl 10 = gtt. 24 

Amyl Nitrite ^l ro — gtt. 30 

Aqua Ammonias TTj, 10 = gtt. 10 

Chloroform TTj, 10 = gtt. 40 

Copaiba ^l 10 = gtt. 18 

Creasotum ^ 10 = gtt. 20 

Extractum Aconiti Fluidum . . , . "Hi 10 = gtt. 25 

223 



224 



APPENDIX. 



Extractum Belladonna? Fluidum 
Buchu 
" Cinchonae 

Colchici Sem. " 
Conii(Fructus) " 
Convallarise " 
Digitalis 
Ergotae 

Gelsemii ' ' 

Hyoscyami " 
Ipecacuanhas " 
Nucis Vomicae ' ' 
Pilocarpi " 

Rhei 

' Scillae, U. S. (with alcohol), Fluidum 

Veratri Viridis Fluidum 
Liquor Acidi Arseniosi 

" Arsenii et Hydrargyri Iodidi 
" Ferri Chloridi 
" Ferri Nitratis 
" Potassii Arsenitis . 
" Sodii Arseniatis . . 
Oleum Amygdalae Amarae 
" Anisi .... 
" Caryophylli ... 
" Cinnamomi . . . 
" Camphoras (Japonicum) 
" Copaibae ... 
" Fceniculi . . . 
" Gaultheriae . 
" Juniperi 

Menthae Piperitae . 
" Phosphoratum 
" Tiglii .... 
Paraldehydum .... 
Solutio Atropines (not safe to trust 
" Cocainae I % " " " " 
" Strychninae " " " 
Spiritus ^Etheris Compositus . 



to " drops") 



TTl io 

TTl IO 
TIL TO 
TIL io 
til io 
TIL io 
TIL IO 
TTL IO 
TIL io 
TIL IO 
TIL io 
TTL IO 
TIL IO 
.TTL IO 
TTL IO 
TTL IO : 
TTL IO 
TIL IO : 
TTL IO : 
TIL IO : 
TIL IO 
TIL IO 
TTL IO : 
TTL IO : 
TTL IO : 
TTL IO : 
TTL IO : 
TTL IO : 
TTL IO : 
TTL IO = 
TTL IO ■ 
TTL IO : 
TTL IO : 
TTL IO : 
TTL IO : 
TTL IO : 
TTL IO : 
TIL IO : 
TTL IO : 



: gtt. 25 

: gtt. 25 

: gtt. 20 

: gtt. 25 

: gtt. 20 

: gtt. 25 

: gtt. 20 

: gtt. 20 

: gtt. 25 

: gtt. 25 

: gtt. 20 

: gtt. 25 

' gtt. 20 

: gtt. 20 

gtt. 20 

gtt. 25 

gtt. IO 

gtt. IO 

gtt. 12 

gtt. IO 

gtt. 10 

gtt. 10 

gtt. 20 

gtt. 20 

gtt. 20 

gtt. 20 

gtt. 20 

gtt. 20 

gtt. 20 

gtt. 20 

gtt. 20 

gtt. 20 : 

gtt. 15 

gtt. 15 : 

gtt. 25 

gtt. IO 

gtt. IO 

gtt. IO 

gtt. 25 



APPENDIX. 



22 



Spiritus ^Etheris Nitrosi . 

" Ammonias Aromaticus 
" '" Chloroformi 

11 " Glonoini I % 

Tinctura Aconiti 

" Fleming's 
" Belladonnas 
" Digitalis . 

Ferri Chloridi . 
" Nucis Vomicae . 

Opii . 
" Opii Camphorata 

" Opii Deodorata . 
'* Stramonii . 
" Veratri Viridis . 
Vinum Colchici Radicis . 
" Seminis . 
Opii . 



m, 10 = gtt. 25 

TTi IO = gtt. 25 
TTi IO = gtt. 25 
TTI, IO = gtt. 25 
TTj, IO = gtt 25 
TTI, IO = gtt. 25 
TTL IO = gtt. 25 
TU IO = gtt. 20 
TTi IO = gtt. 25 
TTt IO = gtt. 25 
TTL IO = gtt. 20 
TTL IO = gtt. 20 
TTL IO = gtt. 2C 
TTL IO = gtt. 20 
TTL IO = gtt. 25 
TTL IO = gtt. 20 
TTL IO = gtt. 20 
TTL IO = gtt. l8 



Note. — The ratio of drops to minims here given is only approxi- 
mate, and refers to drops as dropped from the edge of a bottle-neck 
of the style kept in the shops. It does not refer to drops such as are 
delivered from the fine point of an eye- or medicine-dropper. The 
sizes of the drops delivered by the latter are so varying that no 
reliable ratio to minims can be established. 

Charles Rice. 

New York, Feb. 14, 1890. 



INDEX. 



Note. — The names of the drugs in the index which are set in 
italics do not belong to the Pharmacopeia. The others are official 
and are found in the U. S. P. of 1800. 





PAGE 




PAGE 


Absolute Alcohol 


80 


Acidum Sulphurosum . 


• 67 


Abstraction Nucis Vomica . 


168 


" Tannicum 


71 


Acetanilidum 


106 


" Tartaricum 


70 


Acetic Acid 


68 


Aconite 


113 


Acetum . 


68 


Aconitina . 


Il6 


Acidum Aceticum Dilutum . 


68 


Adeps Pr<zparatus 


206 


" Arsenosum 


42 


Adhesive Plaster 


22 


" Benzoicum 


163 


Adonidin . 


118 


" Boricum 


67 


Adonis Vemalis 


Il8 


" Carbolicum . 


96 


^Ether 


86 


" Citricum 


69 


Agaricin 


204 


" Gallicum 


72 


Agaric us . 


204 


' ' Hydrochloricum 


65 


Alcohol * 


6-81 


' ' Dilutum 


66 


" Amylicum 


76 


' ' Hydrocyanicum 


72 


" Dilutum 


81 


Di- 




" Ethylicum 


76 


lutum 


73 


' ' Methylicum . 


77 


" Lacticum 


72 


Alcoholic Extract of Bella 




" Nitricum 


64 


donna 


m 


" Dilutum . 


65 


Ale . 


?3 


" Nitro- Hydrochlori- 




Aloes .... 


195 


cum . 


66 


Aloin .... 


196 


" Nitro-Hydrochlori- 




Alum .... 


29 


cum Dilutum 


66 


Alumen 


29 


" Oxalicum 


75 


" Exsiccatum . 


30 


" Phosphoricum 


66 


Alumini Sulphas 


30 


" Salicylicum . 


100 


Aluminum Sulphate . 


30 


" Sulphuricum . 


63 


Alumnol 


104 


" " Aro- 




American Hellebore . 


197 


maticum . 


64 


Ammonia . 


12 


" Sulphuricum Dilu- 




Ammoniac . 


151 


tum . 


64 


Plaster 


151 



227 



228 


INDEX. 








PAGE 




PAGE 


Ammoniated Tincture of 


Aromatic Spirit of Ammo- 


Valerian . 


• 159 


nia . 


. 14 


Ammonii Bromidum . 


54 


" Sulphuric Acid . 64 


" Carbonas 


. 14 


Arrow Poison 


. I70 


" Chloridum . 


• 13 


Arsenic 




. 42 


Ammonium Bromide . 


54 


Arseni Iodidum 




• 45 


Carbonate 


. 14 


Ar senium . 




. 42 


Chloride . 


• 13 


Arsenous Acid 




42-45 


Liniment 


• 15 


Asafcetida . 




. 150 


Amygdala Amara 


143 


Aseptol 




. 99 


Amygdalin 


. 144 


Aspidium . 




. 204 


Amy I Hydrate 


76 


Atropinae Sulphas 


• 174 


Amylene Hydrate 


93 


Atropine 


• 174 


Amyl Nitris 


93 


Sulphate 


. 174 


" Nitrite 


93 


Auri Chloridum 


. 25 


Anemonin . 


116 


" et Potassii Bromidum 25 


Antifebrin . 


106 


" " Sodii Chloridum . 24 


Antikamnia 


107 


Aurum 


. 24 


Antimonii et Potassii Tar 








tras 


46 


Balsam of Peru . 


. 141 


Antimonium 


46 


" " Tolu . 


. 141 


Antimony . 


46 


Balsamum Peruvianum . 141 


and Potassiun 


t 


Tolutanum 


. 141 


Tartrate 


46 


Basham's Mixture 


• 33 


Antipyrin ... 


105 


Beer . 


. 83 


Antiseptin . 


60 


Belladonna 


• 171 


Apomorphinae Ilydrochlo 




" Plaster 


. 174 


ras . 


129 


Benzanilid . 


. 107 


Apomorphine Hydrochlo 




Benzoin 


. 163 


rate 


129 


Benzoinated Lard 


. 206 


Aqua Ammonise . 


14 


Benzoinum 


. 163 


Fortior 


14 


Benzonaphthol . 


. 104 


" Camphorse . 


183 


Biniodide of Mercury 


. 40 


' ' Creosoti 


100 


Bismuth 


• 48 


" Fortis 


64 


Bismuth i Subnitras 


. 49 


" Hydrogenii Dioxidi . 


63 


Bismuthum 


• 48 


" Menthae Piperita? 


181 


Bitter Almond . 


. 143 


Argenti Nitras . 


23 


Blackberry . 


• 143 


" " Dilutus 


24 


Black Draught . 


. 143 


" Fusus . 


24 


" Haw 


• 151 


Argentitm .... 


23 


1 ' Snakeroot 


. 117 


Arnica Flowers . 


161 


" Wash 


. 42 


" Plaster . 


162 


Blaud's Pills 


• 34 


" Root 


161 


Blue Gum Tree . 


. 144 


Arnicoe Flores 


161 


" Mass . 


. 41 


" Radix . 


161 


" Ointment 


• 4i 


Aromatic Powder 


184 


" Vitriol 




. 28 





INDEX. 


229 


• 


PAGE 




PAGE 


Borax 


12 


Caryophyllus 


I46 


Boric Acid . 


6 7 


Cascara Sagrada 


138 


Brandy 


8l 


Cascarilla . 


185 


Brazilian Cocoa . 


131 


Castor Oil . 


186 


Brimstone . 


6O 


Catechu 


157 


Bromine 


53 


Cathartic Vegetable Pills 


147 


Bromum 


53 


Caustic Potash . 


4 


Broom Tops 


139 


Cayenne Pepper . 


177 


Brucine 


166 


Cerate of Lead Subacetate 


22 


Bryonia 


148 


Ceratum Plumbi Subacetati 


3 22 


Bryonin 


148 


Cerii Oxalis 


18 


Bryony 


148 


Cerium 


18 


Buchu 


136 


•' Oxalate . 


18 


Burgundy Wine 


83 


Cetaceum . 


206 


Pitch. 


191 


Chalk Mixture . 


17 


Plaster 


191 


Champagne 


82 


Butyl Chloral Hydrate 


91 


Charcoal 


62 






Chinolin 


104 


Cacao Butter 


135 


' ' Tartras 


105 


Caffeine 


158 


Chloral 


88 


Calabar Bean 


141 


" Camphor 


9i 


Calcium 


15 


" Hydras . 


88 


California Buckthorn . 


138 


" Hydrate. 


88 


C a lis ay a 


152 


Chlorinated Lime 


53 


Calomel 


40 


Chlorine 


52 


Calumba 


119 


Chlorodyne . 


84 


Calx .... 


15 


Chloroform 


83 


" Chlorata 


53 


" Liniment 


84 


Camellia Thea . 


158 


Chloroformum 


83 


Camphor . 


182 


Chlorphenol 


99 


" Liniment 


183 


Chlorum 


52 


Water. 


183 


Churrus 


189 


Camphora . 


182 


Cimicifuga . 


117 


Camphorated Tincture o 




Cinchona . 


152 


Opium 


126 


Cinnamomum 


184 


Cannabis Indica . 


189 


Cinnamon . 


184 


Cantharidal Collodion 


135 


Citrate of Magnesia . 


18 


Pitch Plaster 


191 


Citric Acid 


69 


Cantharides 


207 


Citrine Ointment 


4i 


Capsicum . 


177 


Claret 


82 


Plaster 


177 


Cloves 


146 


Carbo 


62 


Coca .... 


131 


Carbolic Acid 


96 


Cocaine Hydrochlorate 


133 


Carbon 


62 


Codeine 


128 


Cardamoms 


189 


•Cod Liver Oil 


206 


Cardamom um 


189 


Coffea Arabica . 


157 


Carron Oil . 


16 


Coffee Plant 


*57 



230 




INDEX. 






PAGE 




Colchici Radix . 


. 20O 


Corrosive Sublimate . 


" . S 


emen . 


. 200 


Colo Bark . 


Colchicum 


. 


. 200 


Cotoin 


" 


Root 


200 


Cotton Wool 


" 


Seed 


200 


Cream Tartar 


Collodion 


. • 


• 135 


Creasote 


Collodium 




135 


Water . 


" 


Cantharidatum 


135 


Creosotum . 


" 


Flexile 


135 


Creta Praeparata . 


" 


Stypticum . 


135 


Croton Chloral . 


Colocynth 




146 


" Oil . 


Colocynthus 


146 


Cupri A rsenis 


Compound Cathartic Pills 


147 


Sulphas 


" 


Chloroform Lin 




Cuprum 




iment 


84 


Cymol . 


" 


Effervescent 








Powder . 


11 


Dandelion . 


" 


Extract of Colo 




Daturine . 




cynth 


146 


Deadly Nightshade 


" 


Infusion of Sen 




Delphine . 




na . 


143 


Deodorized Tincture 


" 


Iron Mixture 


33 


Opium . 


" 


Liquorice Pow 




Diachylon Plaster 




der 


140 


Dialyzed Iron 


" 


Morphine Pow 




Digitaline . 




der 


128 


Digitalis . 


" 


Pills of Anti 




Dilute Acetic Acid 




mony 


48 


" Alcohol . 


" 


Spirit of Ether 


87 


" Hydrochloric Acid . 


" 


Syrup of Sarsa 




" Nitric Acid 




parilla . 


195 


" Silver Nitrate . 


" 


Syrup of Squill; 


5 195 


" Sulphuric Acid 


" 


Tincture of Gen 




Diuretin . 




tian 


169 


DobelVs Solution 


" 


Tincture of Opi 




Donovan's " . 




■um 


127 


Dover's Powder . 


Confectio 


Sennse 


143 


Dried Alum 


Conine 




ISO 




Conium 




149 


Effervescent Magnesium Cit 


Convallaria 


I96 


rate . 


Convallarin 


197 


Elaterin . 


Convallarinum . 


197 


Elaterinum 


Copaiba 




I40 


Elaterium . 


Copper 




27 


Emetine . 


" Arsenite . 


46' 


Emplastrum Ammoniaci 


" Sul 


ihate . 


28 


" Arnicae . 


Corrosive Mercuric Chloride 


- 38 


" Belladonnas 







INDEX. 


231 






PAGE 




PAGE 


Emplastrum Capsici . 


177 


Extractum Gentianas Flui- 




' ' 


Plumbi . 


22 


dum 


169 


" 


Resinas . 


22 


Guaranas Flui- 




" 


Saponis . 


22 


dum 


131 


Emulsum Chloroformi 


84 


" Hydrastis Flui- 




Epsom Salt 


17 


dum 


119 


Ergot 


. 


202 


Hyoscyami Flui- 




Ergo tine 


. 


203 


dum 


176 


Ether 




86 


Ipecacuanhas 




Ethyl Hydrate . 


76 


Fluidum 


157 


Eucalyptol . 


144 


Lobelia? Fluidum 


163 


Eucalyptus . 


144 


Lupulini " 


191 


Eupatorium 


160 


" Nucis Vomicas 




Exalgine 
Exodyne 




109 
107 


Fluidum 
Physostigmatis 


169 


Extractum Aconiti Fluidum 


115 


Fluidum 


142 


" 


Arnicas " 


162 


" Podophylli Flui- 




" 


Belladonnas Rad. 




dum 


117 




Fluidum 


174 


Quassias Fluidum 


138 


" 


Calumbas Flui- 




Rhei 


182 




dum 


120 


" Sarsaparil las Flu- 




" 


Cannabis Indicce 




idum Comp. . 


J 95 




Fluidum 


190 


" Scillas Fluidum . 


195 


" 


Cascara Sagradas 




Senegas " 


131 




Fluidum 


138 


" Sennas " 


143 


" 


Cimieifugas Flui- 




Serpentarias Flu- 






dum 


118 


idum 


184 


" 


Cinchonas Flui- 




" Spigelias Flui- 






dum 


153 


dum 


164 


i ^ 


Cocas Fluidum . 


133 


" Stramonii Semi- 




" 


Colchici Radicis 




nis Fluidum . 


175 




Fluidum 


202 


" Taraxaci Flui- 




" 


Colchici Seminis 




dum 


160 




Fluidum 


202 


" Valerianas " 


159 


" 


Colocynthidis' 




" Veratri Viridis 






Compositus 


147 


Fluidum 


199 


" 


Conii Fluidum . 


150 


Viburni Prunifol. 




" 


Convallarias Flu- 




Fluidum 


151 




idum 


197 


Extract of Aconite 


115 


" 


Colo Fluidum 


185 


' " Colocynth . 


146 


" 


Digitalis Flui- 




" " Convallaria 


197 




dum 


181 


" " Nux Vomica 


169 


" 


Ergotas Fluidum 


203 


" Opium 


126 


" 


Eucalypti Flui- 




" " Physostigma 


142 




dum 


145 


" " Podophyllum 


117 


" 


Gelsemii Flui- 




" " Senega 


131 




dum 


166 


" " Stramonium Seeds 


175 



232 




INDEX. 














PAGE 




PAGE 


Ferr 


et Strychninae Citras 


. I69 


Fluid Ext. of Rhubarb 


182 


" 


" Hypophosphis 


• 52 


" " " Sarsaparilla . 


IQ5 


" 


" Oxidum Hydratum 34 


" " " Senega . 


131 


" 


" " " 




" " " Senna 


143 




cum Magnesia 


• 35 


" " " Serpentaria . 


I84 


Ferri 


c Hydrate . 


• 34 


" " " Spigelia 


I64 


Ferrum 


• 30 


" " " Squill . 


195 


" 


Reductum 


• 34 


" " " Stramonium 




Filix Mas . 


. 204 


Seeds . 


175 


Flaxseed 


• 133 


" " " Taraxacum . 


l60 


Flan 


ing's Tr. of Aconite 


116 


" " " Valerian 


159 


Flexi 


ble Collodion 


• 135 


" " " Veratrum Vi- 




Flowers of Sulphur 


. 6r 


ride . 


199 


Fluid Ext. of Aconite 


115 


" " " Viburnum 




" 


" " Arnica . 


162 


Prunifol. 


151 


" 


" " Belladonna 




Fowler's Solution of Arsenic 


45 




Root . 


174 






" 


" " Calumba 


120 


Gallic Acid 


72 


" 


" " Cannabis In 




Gaultherilene 






188 




dica . 


190 


Gelsemium . 




. 


164 


t < 


" " Cascara Sa 




Gentian 








169 




grada . 


138 


Gentiana 








169 


" 


" " Cimicifuga 


118 


Gin 








82 


" 


" " Cinchona 


153 


Ginger 








189 


" 


" " Coca 


133 


Glonoin 








95 


" 


" " Colchicum 




Glycerine 








in 




Root . 


202 


Glycerinum 






HI 


" 


" " Colchicum 




Glycerite of Boroglycerin . 


in 




Seeds . 


202 


' " Carbolic Acid . 


hi 


" 


" " Conium . 


150 


" " Tannic " 


hi 


'« 


" " Convallaria 


197 


Glycyrrhiza 


140 


" 


" " Coto 


185 


Gold 


24 


" 


" " Digitalis 


181 


" and Potassium Bro- 




" 


" " Ergot . 


203 


mide 


25 


" 


" " Eucalyptus 


145 


" "- Sodium Chloride 


24 


" 


" " Gelsemium 


166 


" Chloride 


25 


" 


" " Gentian 


169 


Golden Seal 


118 


" 


" " Guarana 


131 


Gossypium . 


134 


" 


" " Hops 


191 


Goulard's Cerate 


22 


" 


" " Hydrastis 


119 


" Extract 


22 


" 


" " Hyoscyamus 


176 


Grain Spirit 


76 


" 


" " Ipecac . 


157 


Gran arum . 


145 


" 


" " Lobelia . 


163 


Green Iodide of Mercury . 


40 


" 


" " Nux Vomica 


169 


Griffith's Mixture 


33 


" 


" " Physostigma 


142 


Grindelia . 


162 


" 


" " Podophyllum 


117 


Guaiacol .... 


100 


" 


" " Quassia . 


138 


Ca 


rboni 


ite . 




100 





INDEX. 




233 




PAGE 




PAGE 


Guaiacol Salicylate 


IOO 


Iodoform Ointment 


. GO 


Guaiacoluffi 


IOO 


Iodoformum 


• 59 


Guarana . 


I3T 


lodol .... 


. 60 


Gun Cotton 


134 


Iodophenine 


. iog 


Gtinjah . 


189 


Iodum 


• 56 






Ipecac 


• 155 


Hashish . 


189 


" and Opium Powder 


• 127 


Henbane . 


176 


Ipecacuanha 


• 155 


Hoffman's Anodyne . 


87 


Iron .... 


• 30 


Hops . 


1 go 


Isopelletierine 


• 145 


Huxham^s Tincture . 


153 






Hydracetin .... 


log 


Jaborandi . 


. 136 


Hydrargyri Chloridum Cor- 




Jalap .... 


. 170 


rosivum 


38 


Jalapin 


. 170 


" Chloridum Mite 


40 


Jambul 


. 146 


' ' Cyanidum 


40 


Jamestown Weed 


, 175 


Iodidum Rub- 








rum 


40 


Labarraque's Solution 


• 53 


" Iodidum Viride 


40 


Lactic Acid 


72 


Oxidum Flavum 


40 


Lady Webster Dinner Pills ig6 


Hydrargyrum 


37 


lanolin 


204 


" cum Creta 


4i 


Laudanum . 




. 126 


Hydrastis . 


118 


Lead . 




. 18 


Hydrastininae Hydrochloras 


ng 


" Acetate 




21 


Hydrated Oxide of Iron 


34 


" Plaster 




22 


Hydrochloric Acid 


65 


Levant Wormseed 




159 


Hydrocyanic " 


72 


Lily of the Valley 




ig6 


Hydronaphtol 


104 


Lime . 




15 


Hyoscine Hydrobromate 


177 


" Liniment . 




16 


Hyoscyamine Sulphate 


177 


" Water 




16 


Hyoscyamus 


176 


linimentum Aconiti 




116 


Hypnone .... 


92 


" Ammonise 


15 






Calcis 


16 


Ichthyol .... 


62 


Camphorse 


183 


Indian Hemp . . - . 


i8g 


" Chloroformi 


84 


" Poke 


197 


" " 




" Tobacco . 


162 


Composituir 


L 84 


Infusion of Adonis Vernalis 


118 


Saponis . 


I83 


" " Cascarilla . 


185 


Linseed 


133 


" " Cinchona . 


152 


Liquor Acidi Arsenosi 


45 


" " Digitalis* . 


180 


" Ammonii Acetatis . 


15 


". " Senna 


143 


" Arseni et Hydrar 




Iodide of Arsenic 


45 


gyri Iodidi . 


45 


" " Formyl 


59 


" Calcis 


16 


Iodine .... 


56 


" Ferri Acetatis . 


33 


" Ointment. 


58 


" " et Ammonia 




Iodoform .... 


59 


Acetat 


is 


33 



2 34 


INDEX. 






PAGE 




PAGE 


Liquor Ferri Subsulphatis 


• 33 * 


Iistura Ammoniaci . 


• 151 


Iodi Compositus 


. ss 


Asafcetidas 


• 151 


" Magnesii Citratis 


. 18 


" Cretse 


• 17 


" Plumbi Subacetatis 


. 22 


Ferri Composita 


• 33 


" Potassae . 


• 4 


1 ' Gentiance A Ikalina 


. 169 


" Potassii Arsenitis 


• 45 * 


litigated Caustic 


• 24 


Sodse Chlorata? 


• 53 a 


lonk's Hood 


• 113 


Liquorice Root . 


. 140 IS 


lonsel's Solution 


• 33 


Lithium 


. 12 \ 


lorphina . 


127 


" Benzoate 


12 A 


lorphina; Acetas 


. 127 


" Bromide 


• 55 


" Hydrochloras 


127 


" Carbonate . 


12 


" Sulphas 


127 


" Citrate 


12 IS 


lorphine . 


127 


" Salicylate 


12 IS 


lorphine Acetate 


127 


Lobelia 


162 


" Hydrochlorate 


127 


Lugol's Compound Sol. o 




Sulphate 


127 


Iodine 


- 58 is 


Luriatic Acid 


65 


Lunar Caustic 


24 IS 


lustard 


129 


Lupulus 


. 190 IS 


lyrrh 


138 


Lycopodium 


. 204 JV 


lyrrha 


138 


Madeira 


83 > 


aphtalin . 


104 


Magendies Solution of Mor- 


]S 


"aphthalinum 


104 


phine 


128 IS 


aphtol 


104 


Magnesia . 


17 A 


Hcotine . 


177 


" Citras Effervescent 


; 18 IS 


itrate of Silver 


24 


" Sulphas 


17 > 


itric Acid 


64 


Magnesium Sulphate . 


17 is 


itroglycerin 


95 


Male Fern . 


204 IS 


itrohydrochloric Acid 


66 


Mandrake . 


116 A 


Tor wood' s Tincture . 


199 


Manganese Sulphate . 


36 > 


ux Vomica 


166 


Manganesium 


35 






Mangani Sulphas 


36 C 


il of Camphor . 


183 


Massa Hydrargyri 


41 


' " Eucalyptus 


145 


May Apple 


116 


1 " Garlic 


150 


McMunn s Elixir 


126 ' 


4 " Gaultheria 


1S8 


Meadow Saffron . 


200 


' " Juniper . 


193 


Menthol 


181 


' " Lavender Flowers . 


181 


Mercurial Ointment 


41 


' " Peppermint 


181 


Mercuric Cyanide 


40 


' " Savine 


194 


Mercury 


37 


' " Sweet Birch 


188 


" with Chalk . 


41 


' " Tansy 


160 


Metachloral 


9 1 


1 '.' Tar . 


191 


Methyl Hydrate . 


77 


' " Theobroma , 


135 


" Salicylate 


188 


' " Turpentine 


191 


Mild Mercurous Chloride . 


40 


' " Vitriol . 


63 


Milk of Lime 


16 


intment of Boric Acid 


68 





INDEX. 


235 




PAGE 




PAGE 


Ointment of Mercury . 


41 


Phenolid . 


. I07 


" Nitrate 


4 1 


Phenol 


. 96 


" " Red Oxide o: 




Pheno Resorcin . 


. 108 


Mercury 


41 


Phenyl Salicylate 


. I02 


" " Yellow Oxide 




Phosphorated Oil 


• 51 


of Mercury . 


41 


Phosphoric Acid 


. 66 


" " Veratrine 


199 


Phosphorus 


. 49 


Oleate of Veratrum Viride . 


200 


Physostigma 


. 141 


Oleic Acid . 


no 


Physostigmine 


. 142 


Oleum Betulae Volatile 


188 


Phytolacca . 


. 197 


" Ca??iphorce 


183 


Pi cro toxin . 


. 120 


" Eucalypti 


145 


Picrotoxinum 


. 120 


" Gaultheriae 


188 


Pills of Ferrous Carbonate . 34 


Juniperi . 


193 


" " " Iodide 


• 34 


" Lavandulae Florum . 


181 


" " Phosphorus 


• 51 


" Menthae Piperitae 


181 


Pilocarpinae Hydrochloras . 137 


" Morrhuae 


206 


Pilocarpine Hydrochlorate . 137 


" Olivae 


164 


Pilocarpus . 


. 136 


" Phosphoratum 


51 


Pilulae Aloes et Mastiches . 196 


" Picis Liquidae . 


191 


" AntimoniiCompositae 48 


" Ricini 


186 


" Asafcetidae 


• 151 


" Sabinae . 


194 


" Catharticae Compositae 147 


" Tanaceti 


160 


" Vegetabiles 147 


" Terebinthinae . 


191 


" Ferri Carbonatis . 34 


Theobromatis . 


135 


" Opii 


. 126 


Tiglii 


185 


" Phosphori 


• 51 


Olive Oil . 


164 


Pink Root . 


. 164 


Opium . 


120 


Pix Burgundica . 


. 191 


Oxalic Acid 


75 


" Liquida 


. 191 


Oxide of Zinc 


27 


Plumbi Acetas 


. 21 






Plumbum . 


. 18 


Pancreatin . 


205 


Plummer's Pills . 


• 48 


Paraldehyde 


91 


Podophyllum 


. 116 


Paraldehydum . 


9i 


Porter 


• 83 


Paregoric . 


126 


Port Wine . 


. 82 


Parillin . 


*95 


Poison Nut 


. 166 


Paris Green 


46 


Poke .... 


. 197 


Pasque Flower . 


116 


Pomegranate Rind 


• 145 


Pelletierine .... 


145 


Potassa 


.* 2 


Pepo . 


148 


' ' Sulphurata 


. 61 


Peppermint Camphor . 


181 


Potassii Acetas . 


• 5 


Pepsin . 


205 


" Bicarhonas 


• 3 


Peroxide of Hydrogen 


63 


" Bitartras 


• 7 


Peruvian Bark . 


152 


" Bromidum 


• 54 


Petrolatum 


no 


' ' Carbonas 


• 3 


Phenacetine 


108 


" Chloras . 


. 5 


Phenocoll Hydrochloride 


109 | 


" Citras 


. 5 



236 


INDEX. 






PAGE 






Potassii Cyanidum 


7 


Quinine 




" et Sodii Tartras 


8 


Quinine Sulphate 




" Hypophosphis 


52 






" Iodium . 


57 


Raspail 's Sedative Water . 


" Nitras . 


8 


Rectified Spirit . 




" Permanganas . 


36 


Red Iodide of Mercury 


Potassium Acetate 


5 


Reduced Iron 




" and Sodium Tart 




Resin Plaster 




rate 


8 


Resina Podophylli 




" Bicarbonate 


3 


Resorcin 




" Bitartrate . 


7 


Rincinoleic Acid 




" Bromide 


54 


Rheum 




" Carbonate . 


3 


Rhubarb 




" Citrate 


5 


Rhus Toxicodendron 




" Cyanide 


7 


Rochelle Salt 




11 Hypophosphite 


52 


Rubus 




'* Iodide 


57 


Rue . 




" Nitrate 


8 


Pum . 




" Permanganate 


36 


Ruta Graveolens . 




Potato Spirit 


76 






Prepared Chalk . 


17 


Sabina . - . 




" Lard . 


206 


Saccharin . 




Proof Spirit 


80 


Saccharum Lactis 




Propeny I Alcohol 


in 


Sacred Bark 




Prot iodide of Mercury 


40 


Saleratus . 




Prunus Virginiana 


144 


Salicin 


103 


Prussic Acid 


72 


Salicinum . 




Pulsatilla . 


116 


Salicylic Acid 




Pulvis Aromaticus 


184 


Salol . . • . 




" Effervescens Compos 




Salt. . 




itus 


11 


Saltpetre . 




' ' Ipecacuanha 


156 


Sanitas 




" " et Opii 


127 


Santonica . 




Jalapae Composi- 




Santonin 




tiis 


170 


Saponin 




" Morphinae " 


128 


Saprol 




Pumpkin Seeds . 


148 


Sarsaparilla 




Purple Foxglove 


178 


Sarsaponin . 




Pyridine 


109 


Savin e 




Pyroxylinum 


134 


Scammonium 
Scammony . 




Quaker Buttons . 


166 


Scilla .... 




Quassia 


137 


Scoparius . 




Quevenne's Iron . 


34 


Sea Onion . 




Quicksilver 


37 


Seidlitz Powder . 




Quinina 


153 


Senega 




Quininae Sulphas 


155 


Senna 







INDEX. 


237 




PAGE 




PAGE 


Serpentaria 


I84 


Spigelia 


I64 


Sherry 


82 


Spirit of Camphor 


183 


Silver 


23 


44 44 Ether . 


87 


Nitrate . 


23 


44 4< Mindererus . 


15 


Sinapis 


129 


14 4l Nitrous Ether 


87 


Snake Root 


I84 


Spiritus Athens 


87 


Soap Liniment , 


183 


44 Compositu. 


J 87 


44 Plaster 


22 


Nitrosi 


87 


Soda .... 


9 


" Ammonise Aromati 




Sodii Bicarbonas 


II 


cus 


14 


" Boras 


12 


" Cam phone 


183 


44 Bromidum . 


55 


Chloroformi . 


84 


44 Carbonas . 


10 


44 Frumenti 


8l 


44 Chloridum . 


9 


44 Glonoini 


95 


Hypophosphis . 


52 


44 Lavandula Compos 




44 Salicylas 


102 


itus 


181 


Sodio Theobromine Salicy 




4 ' Rectificatus 


80 


late 


103 


44 Tenuior 


80 


Sodium Bicarbonate . 


11 


44 Vini Gallici . 


81 


44 Borate . 


12 


Spotted Hemlock 


149 


44 Bromide 


55 


Squib V s Mixture 


127 


4 ' Carbonate 


10 


Squill 


194 


4 4 Chloride 


9 


Squirting Cucumber . 


147 


' ' Hypophosphite 


52 


Staphisagria 


116 


44 Salicylate 


102 


Staves Acre 


116 


Solution of Ammonium Ace 




St. Jacob's Oil . 


116 


tate 


15 


Stout .... 


83 


44 ' 4 Arsenic and Mer 




Stramonii Folia . 


175 


curie Iodide 


45 


Stramonium Leaves . 


175 


44 44 Arsenous Acid 


45 


Strophanthin 


171 


44 44 Chlorinated Sods 


1 53 


Strophanthus 


170 


44 44 Ferric Acetate 


33 


Strychnine . 


167 


44 44 44 Subsulphate 


- 33 


Sulphate . 


169 


44 44 Hydrogen Diox 




Styptic Collodion 


135 


ide 


63 


Styracol 


100 


44 44 Iron and Ammo 




Sublimated Sulphur . 


61 


nium Acetate 


33 


Subnitrate of Bismuth 


49 


44 <4 Lead Subacetate 


22 


Sugar of Lead 


21 


44 44 Magnesium Cit 




44 " Milk ' . 


205 


rate 


18 


Sulfonal .... 


92 


44 ' 4 Potassa 


4 


Sulphaminol 


60 


44 44 Porassium Ar 




Sulphur 


60 


senite 


45 


Lotum . 


61 


Sozal .... 


60 


44 Sublimatum . 


61 


Spanish Flies 


207 


Sulphuric Acid . 


63 


Sparteine Sulphate 


139 


Sulphurous Acid 


67 


Spermaceti . 


206 


Sweet Spirit of Nitre . 


87 



2 3 8 



INDEX. 



Syrup of Ferrous Iodide 


• 33 


Tinctura Aloes . 


. 196 


" Ipecac . 


157 


" et Myrrhae 


. 196 


" " Hypophosphites 


• 52 


" Arnicae Flores 


. 161 


" " Iron, Quinine, and 


' ' Radix 


. 161 


Strychnia Phos 




" Asafcetidae 


• 151 


phate 


. 169 


" Belladonnas Folio 




" " Lime . 


. 16 


rum . 


t/4 


" " Rhubarb 


. 182 


" Benzoini 


. 163 


" " Sarsaparilla, Com 




" Composita 163 


pound 


. 195 


' ' Bryoniae 


148 


" " Senega 


• 131 


'" Calumbae 


. 120 


" " Senna . 


• 143 


" Cannabis Indicas 


. 190 


" '* Squill . 


• 195 


" Capsici . 


177 


" " Tar . 


191 


" Catechu Composita 157 


Syrupus Calcis . 


16 


" Chloroformi et 




" Ferri Iodidi . 


33 


Morphines , 


128 


" Ferri - Quininae e 


t 


" Cinicifugae . 


118 


Strychninae Phos 




' ' Cinchonae 


153 


phatum 


169 


Compos 




" Hypophosphitum 


52 


ita . 


153 


" Ipecacuanhas 


157 


" Colchici Seminis 


201 


" Rhei 


182 


" Digitalis 


180 


" Sarsaparillae Com 




" Ferri Chloridi 


32 


posit us 


195 


" Gelsemii 


166 


" Scillae . 


J 95 


" Gentianae Compos 




" Compositus 


195 


ita . 


169 






" Humuli 


191 


Tabacum . 


177 


Hydrastis 


119 


7a??iar Jndien 




143 


" Hyoscyami . 


176 


Tamarinds . 




142 


Iodi . 


58 


Tanacetum 




160 


" Ipecacuanhas et 




Tannic Acid 




7i 


Opii . 


127 


" " Ointment 




72 


" Lavandulce . 


181 


" " Troches 




72 


" Lobeliae 


163 


Tansy 




160 


Opii . 


126 


'Jar . 




191 


" Camphorata 


126 


" Ointment 




191 


' ' C omposita 


127 


Taraxacum 




160 


" Deodorata 


126 


Tartar Emetic . 




46 


" Physostigmatis 


142 


Tartaric Acid 




70 


" Quassias 


138 


Tea Plant . 




158 


" Rhei 


1S2 


Thiersch Powder 




103 


Scillae . 


194 


Thiophene . 




60 


" Serpentarias . 


184 


Thorn Apple 




175 


" Stramonii Seminis 


176 


Thorough wort 




160 


" Strophanthi . 


171 


Thymol 




182 


" Valerianae 


159 


Tinctura Aconiti 




116 


" Veratrum Viridis . 


199 







INDEX. 




239 






PAGE 






PAGE 


Tinctura Zingiberis 


189 


Trinitrin 




95 


Tincture of Aconite . 


Il6 


Trituratio Elaterini 


. I48 


" 


' Aloes 


I96 


Trochisci Acidi Tannici 


72 


" 


' " and Myrrl 


1 I96 


Tropical Fruit Laxative 


143 


" 


' Arnica Flowers 


l6l 


Tully's Powder . 


128 


" 


Root 


l6l 


Turpene 




144 


" 


' Asafcetida 


• 151 








" 


' Belladonna 




Unguentum Acidi Borici 


68 




Leaves . 


174 


" 


" Tannici 


72 


" 


' Benzoin . 


I63 


" 


Diachylon 


22 


" 


' Bryonia 


148 


" 


Hydrargyri 


41 


41 


1 Calumba . 


T20 


" 


" Nitratis 


41 


" 


' Cannabis Indict 


I I9O 


* < 


" Oxidi 




" 


' Capsicum . 


177 




Flav 


1 41 


" 


' Chlo7-oform anc 


i 


" 


" Oxidi 






Morphine 


128 




Rubr 


i 41 


" 


' Cimicifuga 


Il8 


" 


Iodi 


58 


" 


' Cinchona . 


153 


" 


Iodoforrai 


60 


" 


' Colchicum Seec 


L 201 


" 


Sulphuris 


62 


" 


' Digitalis . 


180 


" 


Veratrinae 


199 


" 


' Ferric Chloride 


; 32 


" 


Zinci Oxidi 


27 


" 


' Gelsemium 


166 


Urethan 




93 


" 


' Ginger 


189 








" 


' Hops 


191 


Valerian 




J 59 


" 


' Hydrastis . 


119 


Valerianic Acid . 


x 59 


" 


' Hyoscyamus 


176 


Valero I 




190 


" 


' Iodine 


58 


Vaseline 




no 


< i 


' Ipecac and 




Veratrina 




199 




Opium . 


127 


Veratrum Viride . 


197 


" 


' Lavender . 


181 


Vesicating 


Collodion . 


135 


" • 


' Lobelia 


163 


Viburnum 


Opulus 


151 


" 


' Opium 


126 


" 


Prunifolium 


151 


" 


' Physostigma 


142 


Vinegar 




68 


" 


' Quassia 


138 


Vinum Album 


82 


" 


' Rhubarb . 


182 


" Antimonii 


48 


" 


' Serpentaria 


184 


" Colchici Radix 


202 


" 


' Squill 


194 


" 


" Seminis 


202 


" 


1 Stramonium 




" Ipecacuanhse . 


157 




Seed 


176 


" Porlense . 


82 


" 


' Strophanthus 


171 


" Xe 


'icum . 


82 


1 ' 


' Valerian . 


159 








•« 


' Veratrum Viride 


199 


Warburg 


r Tincture . 


155 


Tobacco 




177 


Washed Sulphur 


61 


Toluene 




191 


Whiskey 




81 


Tragacanl 


h' '. '. 


139 


White Arsenic 


42 


Tragacan 


ha 


139 


Whitewash 


16 


Trimethy 


1 amine , 


161 


White Wine 


82 



240 


INDEX. 






PAGE 




PAGE 


Wild Cherry 


M4 


Yellow Wash 


42 


Wine of Antimony 


48 






" " Colchicum Root 


202 


Zinc .... 


25 


" Seed 


202 


" Chloride 


26 


" Ipecac . 


157 


" Ointment . 


27 


Wines 


82 


" Sulphate 


26 


Wolfsbane . 


113 


Zi.nci Chloridum 


26 


Wood Spirit 


77 


" Oxidum 


27 






" Sulphas 


26 


Yellow Jessamine 


164 


Zincum 


24 


" Mercuric Oxide 


40 


Zingiber 


189 



NOTES ON NEW DRUGS. 



NOTES ON NEW DRUGS. 



NOTES ON NEW DRUGS. 



NOTES ON NEW DRUGS. 



NOTES ON NEW DRUGS. 



NOTES ON NEW DRUGS. 



NOTES ON NEW DRUGS. 



NOTES ON NEW DRUGS. 



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